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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12371 scientific papers returned from the database with the search filters currently being used below.

Dynamics of two key maternal factors that initiate zygotic regulatory programs in ascidian embryos

Authors:
Oda-Ishii I, Abe T, Satou Y
Citation:
Dev Biol. 2018 Mar 14. pii: S0012-1606(18)30031-9. doi: 10.1016/j.ydbio.2018.03.009. [Epub ahead of print]
Epub:
Yes
Abstract:
In animal embryos, transcription is repressed for a definite period of time after fertilization. In the embryo of the ascidian...
Link:
https://www.sciencedirect.com/science/article/pii/S0012160618300319
Delivery Method:
microinjection
Organism or Cell Type:
Ciona intestinalis (ascidian)
Citation Extract:
Oda-Ishii I, Abe T, Satou Y. Dynamics of two key maternal factors that initiate zygotic regulatory programs in ascidian embryos. Dev Biol. 2018 Mar 14. pii: S0012-1606(18)30031-9. doi: 10.1016/j.ydbio.2018.03.009. [Epub ahead of print].

Motor axon navigation relies on Fidgetin-like 1-driven microtubule plus end dynamics

Authors:
Fassier C, Fréal A, Gasmi L, Delphin C, Ten Martin D, De Gois S, Tambalo M, Bosc C, Mailly P, Revenu C, Peris L, Bolte S, Schneider-Maunoury S, Houart C, Nothias F, Larcher JC, Andrieux A, Hazan J
Citation:
J Cell Biol. 2018 Mar 13. pii: jcb.201604108. doi: 10.1083/jcb.201604108. [Epub ahead of print]
Epub:
Yes
Abstract:
During neural circuit assembly, extrinsic signals are integrated into changes in growth cone (GC) cytoskeleton underlying axon...
Link:
http://jcb.rupress.org/content/early/2018/03/12/jcb.201604108
Organism or Cell Type:
zebrafish
Citation Extract:
Fassier C, Fréal A, Gasmi L, Delphin C, Ten Martin D, De Gois S, Tambalo M, Bosc C, Mailly P, Revenu C, Peris L, Bolte S, Schneider-Maunoury S, Houart C, Nothias F, Larcher JC, Andrieux A, Hazan J. Motor axon navigation relies on Fidgetin-like 1-driven microtubule plus end dynamics. J Cell Biol. 2018 Mar 13. pii: jcb.201604108. doi: 10.1083/jcb.201604108. [Epub ahead of print].

TGF-ß Regulates Cathepsin Activation during Normal and Pathogenic Development

Authors:
Flanagan-Steet H, Christian C, Lu PN, Aarnio-Peterson M, Sanman L, Archer-Hartmann S, Azadi P, Bogyo M, Steet RA
Citation:
Cell Rep. 2018 Mar 13;22(11):2964-2977. doi: 10.1016/j.celrep.2018.02.066
Epub:
Not Epub
Abstract:
Cysteine cathepsins play roles during development and disease beyond their function in lysosomal protein turnover. Here, we...
Link:
http://www.cell.com/cell-reports/fulltext/S2211-1247(18)30260-2
Organism or Cell Type:
zebrafish
Citation Extract:
Flanagan-Steet H, Christian C, Lu PN, Aarnio-Peterson M, Sanman L, Archer-Hartmann S, Azadi P, Bogyo M, Steet RA. TGF-ß Regulates Cathepsin Activation during Normal and Pathogenic Development. Cell Rep. 2018 Mar 13;22(11):2964-2977. doi: 10.1016/j.celrep.2018.02.066.

Mir-126 is a conserved modulator of lymphatic development

Authors:
Kontarakis Z, Rossi A, Ramas S, Dellinger MT, Stainier DYR
Citation:
Dev Biol. 2018 Mar 14. pii: S0012-1606(18)30138-6. doi: 10.1016/j.ydbio.2018.03.006. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Organ homeostasis relies upon cellular and molecular processes that restore tissue structure and function in a timely fashion....
Link:
https://www.sciencedirect.com/science/article/pii/S0012160618301386
Organism or Cell Type:
zebrafish
Citation Extract:
Kontarakis Z, Rossi A, Ramas S, Dellinger MT, Stainier DYR. Mir-126 is a conserved modulator of lymphatic development. Dev Biol. 2018 Mar 14. pii: S0012-1606(18)30138-6. doi: 10.1016/j.ydbio.2018.03.006. [Epub ahead of print].

Analysis of hpf1 expression and function in early embryonic development of zebrafish

Authors:
Zhang Z, Sun H, Chen Y, Cao T, Songyang Z, Huang J, Huang Y
Citation:
Dev Genes Evol. 2018 Mar 17. doi: 10.1007/s00427-018-0608-9. [Epub ahead of print]
Epub:
Yes
Abstract:
About 70% of zebrafish (Danio rerio) genes are orthologues of the human's, which are of great interests, but still largely...
Link:
https://link.springer.com/article/10.1007/s00427-018-0608-9
Organism or Cell Type:
zebrafish
Citation Extract:
Zhang Z, Sun H, Chen Y, Cao T, Songyang Z, Huang J, Huang Y. Analysis of hpf1 expression and function in early embryonic development of zebrafish. Dev Genes Evol. 2018 Mar 17. doi: 10.1007/s00427-018-0608-9. [Epub ahead of print].

Phosphorylation states change Otx2 activity for cell proliferation and patterning in the Xenopus embryo

Authors:
Satou Y, Minami K, Hosono E, Okada H, Yasuoka Y, Shibano T, Tanaka T, Taira M
Citation:
Development. 2018 Mar 12;145(5). pii: dev159640. doi: 10.1242/dev.159640
Epub:
Not Epub
Abstract:
The homeodomain transcription factor Otx2 has essential roles in head and eye formation via the negative and positive...
Link:
http://dev.biologists.org/content/145/5/dev159640.full
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Satou Y, Minami K, Hosono E, Okada H, Yasuoka Y, Shibano T, Tanaka T, Taira M. Phosphorylation states change Otx2 activity for cell proliferation and patterning in the Xenopus embryo. Development. 2018 Mar 12;145(5). pii: dev159640. doi: 10.1242/dev.159640.

Time-lapse observation of stepwise regression of Erk activity in zebrafish presomitic mesoderm

Authors:
Sari DWK, Akiyama R, Naoki H, Ishijima H, Bessho Y, Matsui T
Citation:
Sci Rep. 2018 Mar 12;8(1):4335. doi: 10.1038/s41598-018-22619-9
Epub:
Not Epub
Abstract:
During somite segmentation, clock genes oscillate within the posterior presomitic mesoderm (PSM). The temporal information ties...
Link:
https://www.nature.com/articles/s41598-018-22619-9
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sari DWK, Akiyama R, Naoki H, Ishijima H, Bessho Y, Matsui T. Time-lapse observation of stepwise regression of Erk activity in zebrafish presomitic mesoderm. Sci Rep. 2018 Mar 12;8(1):4335. doi: 10.1038/s41598-018-22619-9.

GABA promotes survival and axonal regeneration in identifiable descending neurons after spinal cord injury in larval lampreys

Authors:
Romaus-Sanjurjo D, Ledo-Garcia R, Fernandez-Lopez B, Hanslik K, Morgan JR, Barreiro-Iglesias A, Rodicio MC
Citation:
bioRxiv. 2018:[preprint] doi:10.1101/280891
Epub:
Yes
Abstract:
In mammals, spinal cord injury (SCI) causes permanent disability. The poor regenerative capacity of descending neurons is one...
Link:
https://www.biorxiv.org/content/early/2018/03/12/280891
Delivery Method:
Gelfoam at lesion
Organism or Cell Type:
Petromyzon marinus (lamprey)
Citation Extract:
Romaus-Sanjurjo D, Ledo-Garcia R, Fernandez-Lopez B, Hanslik K, Morgan JR, Barreiro-Iglesias A, Rodicio MC. GABA promotes survival and axonal regeneration in identifiable descending neurons after spinal cord injury in larval lampreys. bioRxiv. 2018:[preprint] doi:10.1101/280891 .

Polycystin-1 loss-of-function is directly linked to an imbalance in G-Protein signaling in the kidney

Authors:
Zhang B, Tran U, Wessely O
Citation:
Development. 2018 Mar 12. pii: dev.158931. doi: 10.1242/dev.158931. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The development of the kidney relies on the establishment and maintenance of a precise tubular diameter of its functional units...
Link:
dev.biologists.org/content/early/2018/03/08/dev.158931
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Zhang B, Tran U, Wessely O. Polycystin-1 loss-of-function is directly linked to an imbalance in G-Protein signaling in the kidney. Development. 2018 Mar 12. pii: dev.158931. doi: 10.1242/dev.158931. [Epub ahead of print].

A zebrafish model for FHL1-opathy reveals loss-of-function effects of human FHL1 mutations

Authors:
Keßler M, Kieltsch A, Kayvanpour E, Katus HA, Schoser B, Schessl J, Just S, Rottbauer W
Citation:
Neuromusc Disord. 2018;[Epub ahead of print] doi:10.1016/j.nmd.2018.03.001
Epub:
Yes
Abstract:
Missense mutations in the four and a half LIM domain 1 (FHL1) gene were found to cause X-linked inherited myopathies of both...
Link:
https://www.sciencedirect.com/science/article/pii/S0960896617312658
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Keßler M, Kieltsch A, Kayvanpour E, Katus HA, Schoser B, Schessl J, Just S, Rottbauer W. A zebrafish model for FHL1-opathy reveals loss-of-function effects of human FHL1 mutations. Neuromusc Disord. 2018;[Epub ahead of print] doi:10.1016/j.nmd.2018.03.001.

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