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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12371 scientific papers returned from the database with the search filters currently being used below.

Intraciliary calcium oscillations initiate vertebrate left-right asymmetry

Authors:
Yuan S, Zhao L, Brueckner M, Sun Z
Citation:
Curr Biol. 2015 Mar 2;25(5):556-67. doi: 10.1016/j.cub.2014.12.051. Epub 2015 Feb 5
Epub:
Not Epub
Abstract:
BACKGROUND: Bilateral symmetry during vertebrate development is broken at the left-right organizer (LRO) by ciliary motility...
Link:
http://www.cell.com/current-biology/abstract/S0960-9822%2814%2901654-6
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Yuan S, Zhao L, Brueckner M, Sun Z. Intraciliary calcium oscillations initiate vertebrate left-right asymmetry. Curr Biol. 2015 Mar 2;25(5):556-67. doi: 10.1016/j.cub.2014.12.051. Epub 2015 Feb 5.

A novel role for Ascl1 in the regulation of mesendoderm formation via HDAC-dependent antagonism of VegT

Authors:
Gao L, Zhu X, Chen G, Ma X, Zhang Y, Khand AA, Shi H, Gu F, Lin H, Chen Y, Zhang H, He L, Tao Q
Citation:
Development. 2016 Feb 1;143(3):492-503. doi: 10.1242/dev.126292. Epub 2015 Dec 23
Epub:
Not Epub
Abstract:
Maternally expressed proteins function in vertebrates to establish the major body axes of the embryo and to establish a pre-...
Link:
http://dev.biologists.org/content/143/3/492.long
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Gao L, Zhu X, Chen G, Ma X, Zhang Y, Khand AA, Shi H, Gu F, Lin H, Chen Y, Zhang H, He L, Tao Q. A novel role for Ascl1 in the regulation of mesendoderm formation via HDAC-dependent antagonism of VegT. Development. 2016 Feb 1;143(3):492-503. doi: 10.1242/dev.126292. Epub 2015 Dec 23.

Cannabinoid Receptor-2 Regulates Embryonic Hematopoietic Stem Cell Development via Prostaglandin E2 and P-Selectin Activity

Authors:
Esain V, Kwan W, Carroll KJ, Cortes M, Liu SY, Frechette GM, Sheward LM, Nissim S, Goessling W, North TE
Citation:
Stem Cells. 2015 Aug;33(8):2596-612. doi: 10.1002/stem.2044. Epub 2015 May 26
Epub:
Not Epub
Abstract:
Cannabinoids (CB) modulate adult hematopoietic stem and progenitor cell (HSPCs) function, however, impact on the production,...
Link:
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4781665/
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Esain V, Kwan W, Carroll KJ, Cortes M, Liu SY, Frechette GM, Sheward LM, Nissim S, Goessling W, North TE. Cannabinoid Receptor-2 Regulates Embryonic Hematopoietic Stem Cell Development via Prostaglandin E2 and P-Selectin Activity. Stem Cells. 2015 Aug;33(8):2596-612. doi: 10.1002/stem.2044. Epub 2015 May 26.

Opposing Nodal/Vg1 and BMP signals mediate axial patterning in embryos of the basal chordate amphioxus

Authors:
Onai T, Yu JK, Blitz IL, Cho KW, Holland LZ
Citation:
Dev Biol. 2010 Aug 1;344(1):377-89. doi: 10.1016/j.ydbio.2010.05.016. Epub 2010 May 19. Erratum in: Dev Biol. 2011 Apr 1;352(1):179
Epub:
Not Epub
Abstract:
The basal chordate amphioxus resembles vertebrates in having a dorsal, hollow nerve cord, a notochord and somites. However, it...
Link:
http://www.sciencedirect.com/science/article/pii/S0012160610003027
Delivery Method:
microinjection
Organism or Cell Type:
Branchiostoma floridae (amphioxis)
Citation Extract:
Onai T, Yu JK, Blitz IL, Cho KW, Holland LZ. Opposing Nodal/Vg1 and BMP signals mediate axial patterning in embryos of the basal chordate amphioxus. Dev Biol. 2010 Aug 1;344(1):377-89. doi: 10.1016/j.ydbio.2010.05.016. Epub 2010 May 19. Erratum in: Dev Biol. 2011 Apr 1;352(1):179.

Bruton's tyrosine kinase revealed as a negative regulator of Wnt-beta-catenin signaling

Authors:
James RG, Biechele TL, Conrad WH, Camp ND, Fass DM, Major MB, Sommer K, Yi X, Roberts BS, Cleary MA, Arthur WT, MacCoss M, Rawlings DJ, Haggarty SJ, Moon RT
Citation:
Sci Signal. 2009 May 26;2(72):ra25. doi: 10.1126/scisignal.2000230
Epub:
Not Epub
Abstract:
Wnts are secreted ligands that activate several receptor-mediated signal transduction cascades. Homeostatic Wnt signaling...
Link:
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4790753/
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
James RG, Biechele TL, Conrad WH, Camp ND, Fass DM, Major MB, Sommer K, Yi X, Roberts BS, Cleary MA, Arthur WT, MacCoss M, Rawlings DJ, Haggarty SJ, Moon RT . Bruton's tyrosine kinase revealed as a negative regulator of Wnt-beta-catenin signaling. Sci Signal. 2009 May 26;2(72):ra25. doi: 10.1126/scisignal.2000230.

Atrogin-1 Deficiency Leads to Myopathy and Heart Failure in Zebrafish

Authors:
Bühler A, Kustermann M, Bummer T, Rottbauer W, Sandri M, Just S
Citation:
Int J Mol Sci. 2016 Jan 30;17(2). pii: E187. doi: 10.3390/ijms17020187
Epub:
Not Epub
Abstract:
Orchestrated protein synthesis and degradation is fundamental for proper cell function. In muscle, impairment of proteostasis...
Link:
http://www.mdpi.com/1422-0067/17/2/187/htm
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bühler A, Kustermann M, Bummer T, Rottbauer W, Sandri M, Just S. Atrogin-1 Deficiency Leads to Myopathy and Heart Failure in Zebrafish. Int J Mol Sci. 2016 Jan 30;17(2). pii: E187. doi: 10.3390/ijms17020187.

mRNA and microRNA transcriptomics analyses in a murine model of dystrophin loss and therapeutic restoration

Authors:
Roberts TC, Blomberg KE, Smith CI, El Andaloussi S, Wood MJ
Citation:
Genom Data. 2015 Dec 2;7:88-9. doi: 10.1016/j.gdata.2015.11.025. eCollection 2016 Mar
Epub:
Not Epub
Abstract:
Duchenne muscular dystrophy (DMD) is a pediatric, X-linked, progressive muscle-wasting disorder caused by loss of function...
Link:
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4778658/
Delivery Method:
peptide-linked
Organism or Cell Type:
mice, mdx
Citation Extract:
Roberts TC, Blomberg KE, Smith CI, El Andaloussi S, Wood MJ. mRNA and microRNA transcriptomics analyses in a murine model of dystrophin loss and therapeutic restoration. Genom Data. 2015 Dec 2;7:88-9. doi: 10.1016/j.gdata.2015.11.025. eCollection 2016 Mar.

A ligand-independent integrin β1 mechanosensory complex guides spindle orientation

Authors:
Petridou NI, Skourides PA
Citation:
Nat Commun. 2016 Mar 8;7:10899. doi: 10.1038/ncomms10899
Epub:
Not Epub
Abstract:
Control of spindle orientation is a fundamental process for embryonic development, morphogenesis and tissue homeostasis, while...
Link:
http://www.nature.com/ncomms/2016/160308/ncomms10899/full/ncomms10899.html
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Petridou NI, Skourides PA. A ligand-independent integrin β1 mechanosensory complex guides spindle orientation. Nat Commun. 2016 Mar 8;7:10899. doi: 10.1038/ncomms10899.

The Wnt receptor Frizzled-4 modulates ADAM13 metalloprotease activity

Authors:
Abbruzzese G, Gorny AK, Kaufmann LT, Cousin H, Kleino I, Steinbeisser H, Alfandari D
Citation:
J Cell Sci. 2015 Mar 15;128(6):1139-49. doi: 10.1242/jcs.163063. Epub 2015 Jan 22
Epub:
Not Epub
Abstract:
Cranial neural crest (CNC) cells are a transient population of stem cells that originate at the border of the neural plate and...
Link:
http://jcs.biologists.org/content/128/6/1139.long
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Abbruzzese G, Gorny AK, Kaufmann LT, Cousin H, Kleino I, Steinbeisser H, Alfandari D. The Wnt receptor Frizzled-4 modulates ADAM13 metalloprotease activity. J Cell Sci. 2015 Mar 15;128(6):1139-49. doi: 10.1242/jcs.163063. Epub 2015 Jan 22.

Quantitative optical coherence tomography imaging of intermediate flow defect phenotypes in ciliary physiology and pathophysiology

Authors:
Huang BK, Gamm UA, Jonas S, Khokha MK, Choma MA
Citation:
J Biomed Opt. 2015 Mar;20(3):030502. doi: 10.1117/1.JBO.20.3.030502
Epub:
Not Epub
Abstract:
Cilia-driven fluid flow is a critical yet poorly understood aspect of pulmonary physiology. Here, we demonstrate that optical...
Link:
http://biomedicaloptics.spiedigitallibrary.org/article.aspx?articleid=2196507
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis, zebrafish
Citation Extract:
Huang BK, Gamm UA, Jonas S, Khokha MK, Choma MA. Quantitative optical coherence tomography imaging of intermediate flow defect phenotypes in ciliary physiology and pathophysiology. J Biomed Opt. 2015 Mar;20(3):030502. doi: 10.1117/1.JBO.20.3.030502.

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