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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12371 scientific papers returned from the database with the search filters currently being used below.

Dendritic Nanoconjugates for Intracellular Delivery of Neutral Oligonucleotides

Authors:
Ming X, Wu L, Carver K, Yuan A, Min Y
Citation:
Nanoscale. 2015;[Epub ahead of print] doi:10.1039/C5NR01665G
Epub:
Yes
Abstract:
Dendrimer-based gene delivery has been constrained by intrinsic toxicity and suboptimal nanostructure. Conjugation of neutral...
Delivery Method:
PAMAM-linked
Organism or Cell Type:
cell culture: cancer cells
Citation Extract:
Ming X, Wu L, Carver K, Yuan A, Min Y. Dendritic Nanoconjugates for Intracellular Delivery of Neutral Oligonucleotides. Nanoscale. 2015;[Epub ahead of print] doi:10.1039/C5NR01665G.

Zdhhc15b Regulates Differentiation of Diencephalic Dopaminergic Neurons in Zebrafish

Authors:
Wang F, Chen X, Shi W, Yao L, Gao M, Yang Y, Hao A
Citation:
J Cell Biochem. 2015 Jun 11. doi: 10.1002/jcb.25256. [Epub ahead of print]
Epub:
Yes
Abstract:
The aspartate-histidine-histidine-cysteine (DHHC) protein family shares a 50-amino acid cysteine-rich domain with a conserved...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wang F, Chen X, Shi W, Yao L, Gao M, Yang Y, Hao A. Zdhhc15b Regulates Differentiation of Diencephalic Dopaminergic Neurons in Zebrafish. J Cell Biochem. 2015 Jun 11. doi: 10.1002/jcb.25256. [Epub ahead of print].

Ca2+ enrichment in culture medium potentiates effect of oligonucleotides

Authors:
Hori S-i, Yamamoto T, Waki R, Wada S, Wada F, Noda M, Obika S
Citation:
Nucl Acids Res. 2015;[Epub ahead of print] doi:10.1093/nar/gkv626
Epub:
Yes
Abstract:
Antisense and RNAi-related oligonucleotides have gained attention as laboratory tools and therapeutic agents based on their...
Delivery Method:
CaCl2, Endo-Porter
Organism or Cell Type:
cell culture: Huh-7 cells
Citation Extract:
Hori S-i, Yamamoto T, Waki R, Wada S, Wada F, Noda M, Obika S. Ca2+ enrichment in culture medium potentiates effect of oligonucleotides. Nucl Acids Res. 2015;[Epub ahead of print] doi:10.1093/nar/gkv626.

The use of urinary and kidney SILAM proteomics to monitor kidney response to high dose morpholino oligonucleotides in the mdx mouse

Authors:
Zhang A, Uaesoontrachoon K, Shaughnessy C, Das JR, Rayavarapu S, Brown KJ, Ray PE, Nagaraju K, van den Anker JN, Hoffman EP, Hathout Y
Citation:
Tox Rep. 2015;2:838-49. doi:10.1016/j.toxrep.2015.05.008
Epub:
Not Epub
Abstract:
Phosphorodiamidate morpholino oligonucleotides (PMO) are used as a promising exon-skipping gene therapy for Duchenne muscular...
Delivery Method:
injection
Organism or Cell Type:
mice, mdx
Citation Extract:
Zhang A, Uaesoontrachoon K, Shaughnessy C, Das JR, Rayavarapu S, Brown KJ, Ray PE, Nagaraju K, van den Anker JN, Hoffman EP, Hathout Y. The use of urinary and kidney SILAM proteomics to monitor kidney response to high dose morpholino oligonucleotides in the mdx mouse. Tox Rep. 2015;2:838-49. doi:10.1016/j.toxrep.2015.05.008.

miR-181a/b control the assembly of visual circuitry by regulating retinal axon specification and growth

Authors:
Carrella S, D'Agostino Y, Barbato S, Huber-Reggi SP, Salierno FG, Manfredi A, Neuhauss SC, Banfi S, Conte I
Citation:
Dev Neurobiol. 2015 Feb 27. doi: 10.1002/dneu.22282. [Epub ahead of print]
Epub:
Yes
Abstract:
Connectivity and function of neuronal circuitry require the correct specification and growth of axons and dendrites. Here we...
Delivery Method:
microinjection
Organism or Cell Type:
Oryzias latipes (medaka)
Citation Extract:
Carrella S, D'Agostino Y, Barbato S, Huber-Reggi SP, Salierno FG, Manfredi A, Neuhauss SC, Banfi S, Conte I. miR-181a/b control the assembly of visual circuitry by regulating retinal axon specification and growth. Dev Neurobiol. 2015 Feb 27. doi: 10.1002/dneu.22282. [Epub ahead of print].

Cross-Scale Integrin Regulation Organizes ECM and Tissue Topology

Authors:
Jülich D, Cobb G, Melo AM, McMillen P, Lawton AK, Mochrie SGJ, Rhoades E, Holley SA
Citation:
Dev Cell. 2015;[Epub ahead of print] doi:10.1016/j.devcel.2015.05.005
Epub:
Yes
Abstract:
The diverse morphologies of animal tissues are underlain by different configurations of adherent cells and extracellular matrix...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Jülich D, Cobb G, Melo AM, McMillen P, Lawton AK, Mochrie SGJ, Rhoades E, Holley SA. Cross-Scale Integrin Regulation Organizes ECM and Tissue Topology. Dev Cell. 2015;[Epub ahead of print] doi:10.1016/j.devcel.2015.05.005.

The chromatin remodeler chd5 is necessary for proper head development during embryogenesis of Danio rerio

Authors:
Bishop B, Ho KK, Tyler K, Smith A, Bonilla S, Leung YF, Ogas J
Citation:
Biochim Biophys Acta. 2015 Jun 16. pii: S1874-9399(15)00129-7. doi: 10.1016/j.bbagrm.2015.06.006. [Epub ahead of print]
Epub:
Yes
Abstract:
The chromatin remodeler CHD5 plays a critical role in tumor suppression and neurogenesis in mammals. CHD5 contributes to gene...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bishop B, Ho KK, Tyler K, Smith A, Bonilla S, Leung YF, Ogas J. The chromatin remodeler chd5 is necessary for proper head development during embryogenesis of Danio rerio. Biochim Biophys Acta. 2015 Jun 16. pii: S1874-9399(15)00129-7. doi: 10.1016/j.bbagrm.2015.06.006. [Epub ahead of print].

Human Kidney Disease-causing INF2 Mutations Perturb Rho/Dia Signaling in the Glomerulus

Authors:
Sun H, Al-Romaih KI, MacRae CA, Pollak MR
Citation:
EBioMedicine. 2014 Nov 13;1(2-3):107-15. doi: 10.1016/j.ebiom.2014.11.009. eCollection 2014 Dec
Epub:
Not Epub
Abstract:
Mutations in Inverted Formin 2 (INF2), a diaphanous formin family protein that regulates actin cytoskeleton dynamics, cause...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sun H, Al-Romaih KI, MacRae CA, Pollak MR. Human Kidney Disease-causing INF2 Mutations Perturb Rho/Dia Signaling in the Glomerulus. EBioMedicine. 2014 Nov 13;1(2-3):107-15. doi: 10.1016/j.ebiom.2014.11.009. eCollection 2014 Dec.

E2F8 as a Novel Therapeutic Target for Lung Cancer

Authors:
Park SA, Platt J, Lee JW, López-Giráldez F, Herbst RS, Koo JS
Citation:
J Natl Cancer Inst. 2015 Jun 18;107(9). pii: djv151. doi: 10.1093/jnci/djv151. Print 2015 Sep
Epub:
Not Epub
Abstract:
BACKGROUND: The E2F members have been divided into transcription activators (E2F1-E2F3) and repressors (E2F4-E2F8). E2F8 with...
Organism or Cell Type:
cell culture: human lung cancer (LC) cells, xenograft models Vivo-Morpholino
Citation Extract:
Park SA, Platt J, Lee JW, López-Giráldez F, Herbst RS, Koo JS. E2F8 as a Novel Therapeutic Target for Lung Cancer. J Natl Cancer Inst. 2015 Jun 18;107(9). pii: djv151. doi: 10.1093/jnci/djv151. Print 2015 Sep.

The Warsaw breakage syndrome-related protein DDX11 is required for ribosomal RNA synthesis and embryonic development

Authors:
Sun X, Chen H, Deng Z, Hu B, Luo H, Zeng X, Han L, Cai G, Ma L
Citation:
Hum Mol Genet. 2015 Jun 18. pii: ddv213. [Epub ahead of print]
Epub:
Yes
Abstract:
DDX11 was recently identified as a cause of Warsaw breakage syndrome (WABS). However, the functional mechanism of DDX11 and the...
Organism or Cell Type:
zebrafish
Citation Extract:
Sun X, Chen H, Deng Z, Hu B, Luo H, Zeng X, Han L, Cai G, Ma L. The Warsaw breakage syndrome-related protein DDX11 is required for ribosomal RNA synthesis and embryonic development. Hum Mol Genet. 2015 Jun 18. pii: ddv213. [Epub ahead of print].

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