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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12419 scientific papers returned from the database with the search filters currently being used below.
There are 12419 scientific papers returned from the database with the search filters currently being used below.
Correction of Clcn1 alternative splicing reverses muscle fiber type transition in mice with myotonic dystrophy
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Citation:
Nat Commun. 2023 Apr 7;14(1):1956. doi: 10.1038/s41467-023-37619-1 Epub:
Not Epub Abstract:
In myotonic dystrophy type 1 (DM1), deregulated alternative splicing of the muscle chloride channel Clcn1 causes myotonia, a... Delivery Method:
intramuscular injection (i.m.) then electroporation Organism or Cell Type:
mice Citation Extract: Hu N, Kim E, Antoury L, Wheeler TM. Correction of Clcn1 alternative splicing reverses muscle fiber type transition in mice with myotonic dystrophy. Nat Commun. 2023 Apr 7;14(1):1956. doi: 10.1038/s41467-023-37619-1. |
Pleiotropic role of TRAF7 in skull-base meningiomas and congenital heart disease
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Citation:
Proc Natl Acad Sci U S A. 2023 Apr 18;120(16):e2214997120. doi: 10.1073/pnas.2214997120. Epub 2023 Apr 12 Epub:
Not Epub Abstract:
While somatic variants of TRAF7 (Tumor necrosis factor receptor-associated factor 7) underlie anterior skull-base meningiomas,... Delivery Method:
microinjection Organism or Cell Type:
Xenopus tropicalis and zebrafish Citation Extract: Mishra-Gorur K, Barak T, Kaulen LD, Henegariu O, Jin SC, Aguilera SM, Yalbir E, Goles G, Nishimura S, Miyagishima D, Djenoune L, Altinok S, Rai DK, Viviano S, Prendergast A, Zerillo C, Ozcan K, Baran B, Sencar L, Goc N, Yarman Y, Ercan-Sencicek AG, Bilguvar K, Lifton RP, Moliterno J, Louvi A, Yuan S, Deniz E, Brueckner M, Gunel M. Pleiotropic role of TRAF7 in skull-base meningiomas and congenital heart disease. Proc Natl Acad Sci U S A. 2023 Apr 18;120(16):e2214997120. doi: 10.1073/pnas.2214997120. Epub 2023 Apr 12. |
The RhoGEF protein Plekhg5 regulates medioapical and junctional actomyosin dynamics of apical constriction during Xenopus gastrulation
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Citation:
Mol Biol Cell. 2023 Apr 12:mbcE22090411. doi: 10.1091/mbc.E22-09-0411. Online ahead of print Epub:
Not Epub Abstract:
Apical constriction results in apical surface reduction in epithelial cells and is a widely used mechanism for epithelial... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Baldwin A, Popov IK, Keller R, Wallingford J, Chang C. The RhoGEF protein Plekhg5 regulates medioapical and junctional actomyosin dynamics of apical constriction during Xenopus gastrulation. Mol Biol Cell. 2023 Apr 12:mbcE22090411. doi: 10.1091/mbc.E22-09-0411. Online ahead of print. |
Monitoring Nrf2/ARE Pathway Activity with a New Zebrafish Reporter System
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Citation:
Int J Mol Sci. 2023 Apr 6;24(7):6804. doi: 10.3390/ijms24076804 Epub:
Not Epub Abstract:
Among multiple cytoprotective mechanisms, eukaryotic cells exhibit a complex transcriptional program relying on the Nrf2... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Badenetti L, Manzoli R, Rubin M, Cozza G, Moro E. Monitoring Nrf2/ARE Pathway Activity with a New Zebrafish Reporter System. Int J Mol Sci. 2023 Apr 6;24(7):6804. doi: 10.3390/ijms24076804. |
Long noncoding RNA HIKER regulates erythropoiesis in Monge's disease via CSNK2B
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Citation:
J Clin Invest. 2023 Apr 6:e165831. doi: 10.1172/JCI165831. Online ahead of print Epub:
Not Epub Abstract:
Excessive Erythrocytosis (EE) is a major hallmark of patients suffering from chronic mountain sickness (CMS, Monge's... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Azad P, Zhou D, Tu HC, Villafuerte FC, Traver D, Rana TM, Haddad GG. Long noncoding RNA HIKER regulates erythropoiesis in Monge's disease via CSNK2B. J Clin Invest. 2023 Apr 6:e165831. doi: 10.1172/JCI165831. Online ahead of print. |
Nodal coordinates the anterior-posterior patterning of germ layers and induces head formation in zebrafish explants
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Citation:
Cell Rep. 2023 Apr 4;42(4):112351. doi: 10.1016/j.celrep.2023.112351. Online ahead of print Epub:
Not Epub Abstract:
Much progress has been made toward generating analogs of early embryos, such as gastruloids and embryoids, in vitro. However,... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Cheng T, Xing YY, Liu C, Li YF, Huang Y, Liu X, Zhang YJ, Zhao GQ, Dong Y, Fu XX, Tian YM, Shu LP, Megason SG, Xu PF. Nodal coordinates the anterior-posterior patterning of germ layers and induces head formation in zebrafish explants. Cell Rep. 2023 Apr 4;42(4):112351. doi: 10.1016/j.celrep.2023.112351. Online ahead of print. |
Activation of lineage competence in hemogenic endothelium precedes the formation of hematopoietic stem cell heterogeneity
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Citation:
Cell Res. 2023 Apr 4. doi: 10.1038/s41422-023-00797-0. Online ahead of print Epub:
Yes Abstract:
Hematopoietic stem and progenitor cells (HSPCs) are considered as a heterogeneous population, but precisely when, where and how... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Xia J, Liu M, Zhu C, Liu S, Ai L, Ma D, Zhu P, Wang L, Liu F. Activation of lineage competence in hemogenic endothelium precedes the formation of hematopoietic stem cell heterogeneity. Cell Res. 2023 Apr 4. doi: 10.1038/s41422-023-00797-0. Online ahead of print. |
Characterization of regeneration initiating cells during Xenopus laevis tail regeneration
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Citation:
bioRxiv. 2023;[preprint] doi:10.1101/2023.03.30.534908 Epub:
Not Epub Abstract:
Embryos are regeneration and wound healing masters. They not only rapidly close their wounds, remodel injured tissue without a... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Radek S, Pavel A, Daniel Z, Ravindra N, Daniel K, Jiri N, Karel Jr. S, Lacina L, Beduya EB, Jiri N, Martin P, Mikael K. Characterization of regeneration initiating cells during Xenopus laevis tail regeneration. bioRxiv. 2023;[preprint] doi:10.1101/2023.03.30.534908 . |
Colec12 and Trail signaling confine cranial neural crest cell trajectories and promote collective cell migration
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Citation:
Dev Dyn. 2023 Jan 24. doi:10.1002/dvdy.569. Online ahead of print Epub:
Yes Abstract:
Background: Collective and discrete neural crest cell (NCC) migratory streams are crucial to vertebrate head patterning.... Delivery Method:
microinjection then electroporation Organism or Cell Type:
Gallus gallus (chick) Citation Extract: McLennan R, Giniunaite R, Hildebrand K, Teddy JM, Kasemeier-Kulesa JC, Bolanos L, Baker RE, Maini PK, Kulesa PM. Colec12 and Trail signaling confine cranial neural crest cell trajectories and promote collective cell migration. Dev Dyn. 2023 Jan 24. doi:10.1002/dvdy.569. Online ahead of print. |
Mutations in VWA8 cause autosomal-dominant retinitis pigmentosa via aberrant mitophagy activation
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Citation:
J Med Genet. 2023 Apr 3:jmg-2022-108888. doi: 10.1136/jmg-2022-108888. Online ahead of print Epub:
Not Epub Abstract:
Background: Although retinitis pigmentosa (RP) is the most common type of hereditary retinal dystrophy, approximately 25%-45%... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Kong L, Chu G, Ma W, Liang J, Liu D, Liu Q, Wei X, Jia S, Gu H, He Y, Luo W, Cao S, Zhou X, He R, Yuan Z. Mutations in VWA8 cause autosomal-dominant retinitis pigmentosa via aberrant mitophagy activation. J Med Genet. 2023 Apr 3:jmg-2022-108888. doi: 10.1136/jmg-2022-108888. Online ahead of print. |