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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

VEGF: A modifier of the del22q11 (DiGeorge) syndrome?

Authors:
Stalmans I, Lambrechts D, De Smet F, Jansen S, Wang J, Maity S, Kneer P, Von Der Ohe M, Swillen A, Maes C, Gewillig M, Molin DG, Hellings P, Boetel T, Haardt M, Compernolle V, Dewerchin M, Plaisance S, Vlietinck R, Emanuel B, Gittenberger-De Groot AC, Scambler P, Morrow B, Driscol DA, Moons L, Esguerra CV, Carmeliet G, Behn-Krappa A, Devriendt K, Collen D, Conway SJ, Carmeliet P
Citation:
Nat Med. 2003 Feb;9(2):173-82
Epub:
Not Epub
Abstract:
Hemizygous deletion of chromosome 22q11 (del22q11) causes thymic, parathyroid, craniofacial and life-threatening...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Stalmans I, Lambrechts D, De Smet F, Jansen S, Wang J, Maity S, Kneer P, Von Der Ohe M, Swillen A, Maes C, Gewillig M, Molin DG, Hellings P, Boetel T, Haardt M, Compernolle V, Dewerchin M, Plaisance S, Vlietinck R, Emanuel B, Gittenberger-De Groot AC, Scambler P, Morrow B, Driscol DA, Moons L, Esguerra CV, Carmeliet G, Behn-Krappa A, Devriendt K, Collen D, Conway SJ, Carmeliet P. VEGF: A modifier of the del22q11 (DiGeorge) syndrome?. Nat Med. 2003 Feb;9(2):173-82.

15-Zinc finger protein Bloody Fingers is required for zebrafish morphogenetic movements during neurulation

Authors:
Sumanas S, Zhang B, Dai R, Lin S
Citation:
Dev Biol. 2005 Jul 1;283(1):85-96.
Epub:
Not Epub
Abstract:
A novel zebrafish gene bloody fingers (blf) encoding a 478 amino acid protein containing fifteen C(2)H(2) type zinc fingers was...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sumanas S, Zhang B, Dai R, Lin S. 15-Zinc finger protein Bloody Fingers is required for zebrafish morphogenetic movements during neurulation. Dev Biol. 2005 Jul 1;283(1):85-96..

A conserved mechanism for vertebrate mesoderm specification in urodele amphibians and mammals

Authors:
Swiers G, Chen YH, Johnson AD, Loose M
Citation:
Dev Biol. 2010 Apr 13. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Understanding how mesoderm is specified during development is a fundamental issue in biology, and it has been studied...
Delivery Method:
Microinjection
Organism or Cell Type:
Axolotl
Citation Extract:
Swiers G, Chen YH, Johnson AD, Loose M. A conserved mechanism for vertebrate mesoderm specification in urodele amphibians and mammals. Dev Biol. 2010 Apr 13. [Epub ahead of print].

A conserved molecular pathway mediates myoblast fusion in insects and vertebrates

Authors:
Srinivas BP, Woo J, Leong WY, Roy S
Citation:
Nat Genet. 2007 Jun;39(6):781-6. Epub 2007 May 27
Epub:
Not Epub
Abstract:
Skeletal muscles arise by fusion of precursor cells, myoblasts, into multinucleated fibers. In vertebrates, mechanisms...
Organism or Cell Type:
zebrafish
Citation Extract:
Srinivas BP, Woo J, Leong WY, Roy S. A conserved molecular pathway mediates myoblast fusion in insects and vertebrates. Nat Genet. 2007 Jun;39(6):781-6. Epub 2007 May 27.

A Developmental Requirement for HIRA-Dependent H3.3 Deposition Revealed at Gastrulation in Xenopus

Authors:
Szenker E, Lacoste N, Almouzni G
Citation:
Cell Reports. 2012;[Epub ahead of print] doi:10.1016/j.celrep.2012.05.006
Epub:
Not Epub
Abstract:
Discovering how histone variants that mark distinct chromatin regions affect a developmental program is a major challenge in...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Szenker E, Lacoste N, Almouzni G. A Developmental Requirement for HIRA-Dependent H3.3 Deposition Revealed at Gastrulation in Xenopus. Cell Reports. 2012;[Epub ahead of print] doi:10.1016/j.celrep.2012.05.006 .

A genetic screen in zebrafish identifies cilia genes as a principal cause of cystic kidney

Authors:
Sun Z, Amsterdam A, Pazour GJ, Cole DG, Miller MS, Hopkins N
Citation:
Development. 2004 Aug;131(16):4085-93. Epub 2004 Jul 21
Epub:
Not Epub
Abstract:
Polycystic kidney disease (PKD) is a common human genetic illness. It is characterized by the formation of multiple kidney...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sun Z, Amsterdam A, Pazour GJ, Cole DG, Miller MS, Hopkins N. A genetic screen in zebrafish identifies cilia genes as a principal cause of cystic kidney. Development. 2004 Aug;131(16):4085-93. Epub 2004 Jul 21.

A histone demethylase is necessary for regeneration in zebrafish

Authors:
Stewart S, Tsun ZY, Izpisua Belmonte JC
Citation:
Proc Natl Acad Sci U S A. 2009 Nov 24;106(47):19889-94. Epub 2009 Nov 6
Epub:
Not Epub
Abstract:
Urodele amphibians and teleost fish regenerate amputated body parts via a process called epimorphic regeneration. A hallmark of...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Stewart S, Tsun ZY, Izpisua Belmonte JC. A histone demethylase is necessary for regeneration in zebrafish. Proc Natl Acad Sci U S A. 2009 Nov 24;106(47):19889-94. Epub 2009 Nov 6.

A morpholino oligomer targeting highly conserved internal ribosome entry site sequence is able to inhibit multiple species of picornavirus

Authors:
Stone JK, Rijnbrand R, Stein DA, Ma Y, Yang Y, Iversen PL, Andino R
Citation:
Antimicrob Agents Chemother. 2008 Jun;52(6):1970-81. Epub 2008 Mar 17.
Epub:
Not Epub
Abstract:
Members of the genera Enterovirus and Rhinovirus (family Picornaviridae) cause a wide range of human diseases. An established...
Delivery Method:
peptide-coupled
Organism or Cell Type:
mice, cell cultures
Citation Extract:
Stone JK, Rijnbrand R, Stein DA, Ma Y, Yang Y, Iversen PL, Andino R. A morpholino oligomer targeting highly conserved internal ribosome entry site sequence is able to inhibit multiple species of picornavirus. Antimicrob Agents Chemother. 2008 Jun;52(6):1970-81. Epub 2008 Mar 17..

A mutant form of MeCP2 protein associated with human Rett syndrome cannot be displaced from methylated DNA by notch in Xenopus embryos

Authors:
Stancheva I, Collins AL, Van den Veyver IB, Zoghbi H, Meehan RR
Citation:
Mol Cell. 2003 Aug;12(2):425-35
Epub:
Not Epub
Abstract:
MeCP2 is a DNA binding protein that represses transcription of methylated genes in vitro, but the endogenous function of MeCP2...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Stancheva I, Collins AL, Van den Veyver IB, Zoghbi H, Meehan RR. A mutant form of MeCP2 protein associated with human Rett syndrome cannot be displaced from methylated DNA by notch in Xenopus embryos. Mol Cell. 2003 Aug;12(2):425-35.

A perturbation model of the gene regulatory network for oral and aboral ectoderm specification in the sea urchin embryo

Authors:
Su YH, Li E, Geiss GK, Longabaugh WJ, Krämer A, Davidson EH
Citation:
Dev Biol. 2009 Mar 4. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The current gene regulatory network (GRN) for the sea urchin embryo pertains to pregastrular specification functions in the...
Organism or Cell Type:
sea urchin
Citation Extract:
Su YH, Li E, Geiss GK, Longabaugh WJ, Krämer A, Davidson EH. A perturbation model of the gene regulatory network for oral and aboral ectoderm specification in the sea urchin embryo. Dev Biol. 2009 Mar 4. [Epub ahead of print].

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