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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
hrT is required for cardiovascular development in zebrafish
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Citation:
Development. 2002 Nov 1;129(21):5093-5101 Epub:
Not Epub Abstract:
The recently identified zebrafish T-box gene hrT is expressed in the developing heart and in the endothelial cells forming the... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Szeto DP, Griffin KJ, Kimelman D. hrT is required for cardiovascular development in zebrafish. Development. 2002 Nov 1;129(21):5093-5101. |
Hypoxia Disruption of Vertebrate CNS Pathfinding through EphrinB2 Is Rescued by Magnesium
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Citation:
PLoS Genet. 2012;8(4):e1002638. doi:10.1371/journal.pgen.1002638 Epub:
Not Epub Abstract:
The mechanisms of hypoxic injury to the developing human brain are poorly understood, despite being a major cause of chronic... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Stevenson TJ, Trinh T, Kogelschatz C, Fujimoto E, Lush ME, Piotrowski C, Brimley CJ, Bonkowsky JL. Hypoxia Disruption of Vertebrate CNS Pathfinding through EphrinB2 Is Rescued by Magnesium. PLoS Genet. 2012;8(4):e1002638. doi:10.1371/journal.pgen.1002638. |
Identification of a Novel BBS Gene (BBS12) Highlights the Major Role of a Vertebrate-Specific Branch of Chaperonin-Related Proteins in Bardet-Biedl Syndrome
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Citation:
Am J Hum Genet. 2007 Jan;80(1):1-11. Epub 2006 Nov 15 Epub:
Not Epub Abstract:
Bardet-Biedl syndrome (BBS) is primarily an autosomal recessive ciliopathy characterized by progressive retinal degeneration,... Organism or Cell Type:
zebrafish Citation Extract: Stoetzel C, Muller J, Laurier V, Davis EE, Zaghloul NA, Vicaire S, Jacquelin C, Plewniak F, Leitch CC, Sarda P, Hamel C, de Ravel TJ, Lewis RA, Friederich E, Thibault C, Danse JM, Verloes A, Bonneau D, Katsanis N, Poch O, Mandel JL, Dollfus H. Identification of a Novel BBS Gene (BBS12) Highlights the Major Role of a Vertebrate-Specific Branch of Chaperonin-Related Proteins in Bardet-Biedl Syndrome. Am J Hum Genet. 2007 Jan;80(1):1-11. Epub 2006 Nov 15. |
Identification of an N-terminal glycogen synthase kinase 3 phosphorylation site which regulates the functional localisation of polycystin-2 in vivo and in vitro
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Citation:
Hum Mol Genet. 2006 May 1;15(9):1465-73. Epub 2006 Mar 21. Epub:
Not Epub Abstract:
PKD2 is mutated in 15% of patients with autosomal dominant polycystic kidney disease (ADPKD). Polycystin-2 (PC2), the PKD2... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Streets AJ, Moon DJ, Kane ME, Obara T, Ong AC. Identification of an N-terminal glycogen synthase kinase 3 phosphorylation site which regulates the functional localisation of polycystin-2 in vivo and in vitro. Hum Mol Genet. 2006 May 1;15(9):1465-73. Epub 2006 Mar 21.. |
IFATS Series: Stem Cell Antigen-1 Positive Ear Mesenchymal Stem Cells (EMSC) Display Enhanced Adipogenic Potential
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Citation:
Stem Cells. 2008 Jul 3. [Epub ahead of print] Epub:
Not Epub Abstract:
Hyperplasia is a major contributor to the increase in adipose tissue mass that is characteristic of obesity. However, the... Organism or Cell Type:
Ear mesenchymal stem cells (EMSC) Citation Extract: Staszkiewicz J, Gimble J, Manuel JA, Gawronska-Kozak B. IFATS Series: Stem Cell Antigen-1 Positive Ear Mesenchymal Stem Cells (EMSC) Display Enhanced Adipogenic Potential. Stem Cells. 2008 Jul 3. [Epub ahead of print]. |
In vivo and in vitro assessment of cardiac beta-adrenergic receptors in larval zebrafish (Danio rerio)
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Citation:
J Exp Biol. 2011 May 1;214(Pt 9):1445-1457 Epub:
Not Epub Abstract:
β-Adrenergic receptors (βARs) are crucial for maintaining the rate and force of cardiac muscle contraction in vertebrates.... Organism or Cell Type:
zebrafish Citation Extract: Steele SL, Yang X, Debiais-Thibaud M, Schwerte T, Pelster B, Ekker M, Tiberi M, Perry SF. In vivo and in vitro assessment of cardiac beta-adrenergic receptors in larval zebrafish (Danio rerio). J Exp Biol. 2011 May 1;214(Pt 9):1445-1457. |
Inhibition of Muscle Differentiation by the Novel Muscleblind-Related Protein CHCR
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Citation:
Dev Biol. 2002 Oct 1;250(1):218 Epub:
Not Epub Abstract:
Growth factor withdrawal from proliferating myoblasts induces the expression of muscle-specific genes essential for myogenesis... Delivery Method:
Scrape Delivery Organism or Cell Type:
cell culture: C2C12 cells Citation Extract: Squillace R, Chenault D, Wang E. Inhibition of Muscle Differentiation by the Novel Muscleblind-Related Protein CHCR. Dev Biol. 2002 Oct 1;250(1):218. |
Inhibition of RNA virus infections with peptide-conjugated morpholino oligomers
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Citation:
Curr Pharm Des. 2008;14(25):2619-34 Epub:
Not Epub Abstract:
RNA virus infections cause immense human disease burdens globally, and few effective antiviral drugs are available for their... Delivery Method:
peptide-coupled Citation Extract: Stein DA. Inhibition of RNA virus infections with peptide-conjugated morpholino oligomers. Curr Pharm Des. 2008;14(25):2619-34. |
Inhibition of Vesivirus infections in mammalian tissue culture with antisense morpholino oligomers
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Citation:
Antisense Nucleic Acid Drug Dev. 2001 Oct;11(5):317-25 Epub:
Not Epub Abstract:
Caliciviruses infect and cause disease in animals and humans. They are nonenveloped, positive-stranded RNA viruses with a... Delivery Method:
Scrape Delivery Organism or Cell Type:
cell culture: PK-15 and Vero cells Citation Extract: Stein DA, Skilling DE, Iversen PL, Smith AW. Inhibition of Vesivirus infections in mammalian tissue culture with antisense morpholino oligomers. Antisense Nucleic Acid Drug Dev. 2001 Oct;11(5):317-25. |
Initiation of DNA replication after fertilization is regulated by p90Rsk at pre-RC/pre-IC transition in starfish eggs
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Citation:
Proc Natl Acad Sci U S A. 2010 Mar 16;107(11):5006-11. Epub 2010 Feb 25 Epub:
Not Epub Abstract:
Initiation of DNA replication in eukaryotic cells is controlled through an ordered assembly of protein complexes at replication... Delivery Method:
Microinjection Organism or Cell Type:
Starfish Asterina pectinifera Citation Extract: Tachibana K, Mori M, Matsuhira T, Karino T, Inagaki T, Nagayama A, Nishiyama A, Hara M, Kishimoto T. Initiation of DNA replication after fertilization is regulated by p90Rsk at pre-RC/pre-IC transition in starfish eggs. Proc Natl Acad Sci U S A. 2010 Mar 16;107(11):5006-11. Epub 2010 Feb 25. |