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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12371 scientific papers returned from the database with the search filters currently being used below.

Knock-down of the Zebrafish Orthologue of the Retinitis Pigmentosa 2 (RP2) Gene Results in Retinal Degeneration

Authors:
Shu X, Zeng Z, Gautier P, Lennon A, Gakovic M, Cheetham ME, Patton EE, Wright AF
Citation:
Invest Ophthalmol Vis Sci. 2011 Jan 31. [Epub ahead of print]
Epub:
Not Epub
Abstract:
PURPOSE The present study investigates the expression and function of the zebrafish orthologue of the Retinitis Pigmentosa 2 (...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Shu X, Zeng Z, Gautier P, Lennon A, Gakovic M, Cheetham ME, Patton EE, Wright AF. Knock-down of the Zebrafish Orthologue of the Retinitis Pigmentosa 2 (RP2) Gene Results in Retinal Degeneration. Invest Ophthalmol Vis Sci. 2011 Jan 31. [Epub ahead of print].

Knocked down and out: PACAP in development, reproduction and feeding

Authors:
Sherwood NM, Adams BA, Isaac ER, Wu S, Fradinger EA
Citation:
Peptides. 2007 Sep;28(9):1680-7. Epub 2007 Mar 24.
Epub:
Not Epub
Abstract:
One approach to understanding the role of PACAP in vivo is to knockdown the translation of PACAP mRNA to protein or to knock...
Organism or Cell Type:
zebrafish
Citation Extract:
Sherwood NM, Adams BA, Isaac ER, Wu S, Fradinger EA. Knocked down and out: PACAP in development, reproduction and feeding. Peptides. 2007 Sep;28(9):1680-7. Epub 2007 Mar 24..

Light-controlled gene silencing in zebrafish embryos

Authors:
Shestopalov IA, Sinha S, Chen JK
Citation:
Nat Chem Biol. 2007 Oct;3(10):650-1. Epub 2007 Aug 23.
Epub:
Not Epub
Abstract:
Functional genomic studies in zebrafish frequently use synthetic oligonucleotides called morpholinos that block RNA splicing or...
Organism or Cell Type:
zebrafish
Citation Extract:
Shestopalov IA, Sinha S, Chen JK. Light-controlled gene silencing in zebrafish embryos. Nat Chem Biol. 2007 Oct;3(10):650-1. Epub 2007 Aug 23..

Long-Range Ca2+ Waves Transmit Brain-Damage Signals to Microglia

Authors:
Sieger D, Moritz C, Ziegenhals T, Prykhozhij S, Peri F
Citation:
Dev Cell. 2012;[Epub ahead of print] doi:10.1016/j.devcel.2012.04.012
Epub:
Not Epub
Abstract:
Microglia are the resident phagocytes of the brain that are responsible for the clearance of injured neurons, an essential step...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sieger D, Moritz C, Ziegenhals T, Prykhozhij S, Peri F. Long-Range Ca2+ Waves Transmit Brain-Damage Signals to Microglia. Dev Cell. 2012;[Epub ahead of print] doi:10.1016/j.devcel.2012.04.012.

Maternal induction of ventral fate by zebrafish radar

Authors:
Sidi S, Goutel C, Peyrieras N, Rosa FM
Citation:
Proc Natl Acad Sci U S A 2003 Feb 24; [epub ahead of print]- get citation 100(6):3315-3320
Epub:
Not Epub
Abstract:
In vertebrate embryos, maternal determinants are thought to preestablish the dorsoventral axis by locally activating zygotic...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sidi S, Goutel C, Peyrieras N, Rosa FM. Maternal induction of ventral fate by zebrafish radar. Proc Natl Acad Sci U S A 2003 Feb 24; [epub ahead of print]- get citation 100(6):3315-3320.

Maternal-zygotic medaka mutants for fgfr1 reveal its essential role in the migration of the axial mesoderm but not the lateral mesoderm

Authors:
Shimada A, Yabusaki M, Niwa H, Yokoi H, Hatta K, Kobayashi D, Takeda H
Citation:
Development. 2008 Jan;135(2):281-90
Epub:
Not Epub
Abstract:
The medaka fish (Oryzias latipes) is an emerging model organism for which a variety of unique developmental mutants have now...
Organism or Cell Type:
medaka
Citation Extract:
Shimada A, Yabusaki M, Niwa H, Yokoi H, Hatta K, Kobayashi D, Takeda H. Maternal-zygotic medaka mutants for fgfr1 reveal its essential role in the migration of the axial mesoderm but not the lateral mesoderm. Development. 2008 Jan;135(2):281-90.

Modelling a ciliopathy: Ahi1 knockdown in model systems reveals an essential role in brain, retinal, and renal development

Authors:
Simms RJ, Hynes AM, Eley L, Inglis D, Chaudhry B, Dawe HR, Sayer JA
Citation:
Cell Mol Life Sci. 2011 Sep 29. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Joubert syndrome and related diseases (JSRD) are cerebello-oculo-renal syndromes with phenotypes including cerebellar...
Organism or Cell Type:
zebrafish
Citation Extract:
Simms RJ, Hynes AM, Eley L, Inglis D, Chaudhry B, Dawe HR, Sayer JA. Modelling a ciliopathy: Ahi1 knockdown in model systems reveals an essential role in brain, retinal, and renal development. Cell Mol Life Sci. 2011 Sep 29. [Epub ahead of print].

Modification of Alternative Splicing of Mcl-1 Pre-mRNA Using Antisense Morpholino Oligonucleotides Induces Apoptosis in Basal Cell Carcinoma Cells

Authors:
Shieh JJ, Liu KT, Huang SW, Chen YJ, Hsieh TY
Citation:
J Invest Dermatol. 2009 Oct;129(10):2497-506. doi: 10.1038/jid.2009.83. Epub 2009 Apr 16.
Epub:
Not Epub
Abstract:
Myeloid cell leukemia-1 (Mcl-1, Mcl-1L) is an anti-apoptotic protein of the Bcl-2 family that acts as a critical molecule in...
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: human basal skin cell carcinoma line
Citation Extract:
Shieh JJ, Liu KT, Huang SW, Chen YJ, Hsieh TY. Modification of Alternative Splicing of Mcl-1 Pre-mRNA Using Antisense Morpholino Oligonucleotides Induces Apoptosis in Basal Cell Carcinoma Cells. J Invest Dermatol. 2009 Oct;129(10):2497-506. doi: 10.1038/jid.2009.83. Epub 2009 Apr 16..

Multiple roles for Med12 in vertebrate endoderm development

Authors:
Shin CH, Chung WS, Hong SK, Ober EA, Verkade H, Field HA, Huisken J, Stainier DY
Citation:
Dev Biol. 2008 May 15;317(2):467-79. Epub 2008 Mar 4
Epub:
Not Epub
Abstract:
In zebrafish, the endoderm originates at the blastula stage from the most marginal blastomeres. Through a series of complex...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Shin CH, Chung WS, Hong SK, Ober EA, Verkade H, Field HA, Huisken J, Stainier DY. Multiple roles for Med12 in vertebrate endoderm development. Dev Biol. 2008 May 15;317(2):467-79. Epub 2008 Mar 4.

Muscle contraction controls skeletal morphogenesis through regulation of chondrocyte convergent extension

Authors:
Shwartz Y, Farkas Z, Stern T, Aszódi A, Zelzer E
Citation:
Dev Biol. 2012;[Epub ahead of print] doi: 10.1016/j.ydbio.2012.07.026
Epub:
Not Epub
Abstract:
Convergent extension driven by mediolateral intercalation of chondrocytes is a key process that contributes to skeletal growth...
Organism or Cell Type:
zebrafish
Citation Extract:
Shwartz Y, Farkas Z, Stern T, Aszódi A, Zelzer E. Muscle contraction controls skeletal morphogenesis through regulation of chondrocyte convergent extension. Dev Biol. 2012;[Epub ahead of print] doi: 10.1016/j.ydbio.2012.07.026.

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