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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12371 scientific papers returned from the database with the search filters currently being used below.
There are 12371 scientific papers returned from the database with the search filters currently being used below.
Microsomal Triglyceride Transfer Protein Is Required for Yolk Lipid Utilization and Absorption of Dietary Lipids in Zebrafish Larvae
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Citation:
Biochemistry. 2006 Dec 26;45(51):15179-15187 Epub:
Not Epub Abstract:
Although the absorption, transport, and catabolism of dietary lipids have been studied extensively in great detail in mammals... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Schlegel A, Stainier DY. Microsomal Triglyceride Transfer Protein Is Required for Yolk Lipid Utilization and Absorption of Dietary Lipids in Zebrafish Larvae. Biochemistry. 2006 Dec 26;45(51):15179-15187. |
Mutant-specific gene expression profiling identifies SRY-related HMG box 11b (SOX11b) as a novel regulator of vascular development in zebrafish
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Citation:
Mol Cells. 2013 Feb;35(2):166-72. doi: 10.1007/s10059-013-2307-8. Epub 2013 Feb 21 Epub:
Not Epub Abstract:
Previous studies have identified two zebrafish mutants, cloche and groom of cloche, which lack the majority of the endothelial... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Schmitt CE, Woolls MJ, Jin SW. Mutant-specific gene expression profiling identifies SRY-related HMG box 11b (SOX11b) as a novel regulator of vascular development in zebrafish. Mol Cells. 2013 Feb;35(2):166-72. doi: 10.1007/s10059-013-2307-8. Epub 2013 Feb 21. |
Mutation of zebrafish Snapc4 is associated with loss of the intrahepatic biliary network
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Citation:
Dev Biol. 2012 Mar 1;363(1):128-37. doi: 10.1016/j.ydbio.2011.12.025. Epub 2011 Dec 23 Epub:
Not Epub Abstract:
Biliary epithelial cells line the intrahepatic biliary network, a complex three-dimensional network of conduits. The loss of... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Schaub M, Nussbaum J, Verkade H, Ober EA, Stainier DY, Sakaguchi TF. Mutation of zebrafish Snapc4 is associated with loss of the intrahepatic biliary network. Dev Biol. 2012 Mar 1;363(1):128-37. doi: 10.1016/j.ydbio.2011.12.025. Epub 2011 Dec 23. |
Nuclear antisense effects of neutral, anionic and cationic oligonucleotide analogs
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Citation:
Nucleic Acids Res. 2001 Oct 1;29(19):3965-74 Epub:
Not Epub Abstract:
The antisense activity of oligomers with 2'-O-methyl (2'-O-Me) phosphorothioate, 2'-O-methoxyethyl (2'-O-... Delivery Method:
scrape loading and free uptake Organism or Cell Type:
cell culture: HeLa cells Citation Extract: Sazani P, Kang SH, Maier MA, Wei C, Dillman J, Summerton J, Manoharan M, Kole R. Nuclear antisense effects of neutral, anionic and cationic oligonucleotide analogs. Nucleic Acids Res. 2001 Oct 1;29(19):3965-74. |
olig1 expression identifies developing oligodendrocytes in zebrafish and requires hedgehog and notch signaling
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Citation:
Dev Dyn. 2009 Feb 27. [Epub ahead of print] Epub:
Not Epub Abstract:
Myelin, the isolating sheath around large diameter axons, is formed in the central nervous system (CNS) by oligodendrocytes. We... Organism or Cell Type:
zebrafish Citation Extract: Schebesta M, Serluca FC. olig1 expression identifies developing oligodendrocytes in zebrafish and requires hedgehog and notch signaling. Dev Dyn. 2009 Feb 27. [Epub ahead of print]. |
Prohibitin1 acts as a neural crest specifier in Xenopus development by repressing the transcription factor E2F1
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Citation:
Development. 2010 Dec;137(23):4073-81 Epub:
Not Epub Abstract:
Prohibitin 1 (phb1), which was initially described as an inhibitor of cell proliferation, is a highly conserved protein found... Delivery Method:
Microinjection Organism or Cell Type:
Xenopus Citation Extract: Schneider M, Schambony A, Wedlich D. Prohibitin1 acts as a neural crest specifier in Xenopus development by repressing the transcription factor E2F1. Development. 2010 Dec;137(23):4073-81. |
Quantitative evaluation of morpholino-mediated protein knockdown of GFP, MSX1, and PAX7 during tail regeneration in Ambystoma mexicanum
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Citation:
Dev Dyn. 2005 Jan;232(1):162-70. Epub:
Not Epub Abstract:
Vertebrate regeneration is a fascinating but poorly understood biological phenomena. Urodele amphibians such as Ambystoma... Delivery Method:
Electroporation Organism or Cell Type:
Ambystoma mexicanum (axolotl) Citation Extract: Schnapp E, Tamaka EM. Quantitative evaluation of morpholino-mediated protein knockdown of GFP, MSX1, and PAX7 during tail regeneration in Ambystoma mexicanum. Dev Dyn. 2005 Jan;232(1):162-70.. |
Repeat-Dose Toxicology Evaluation in Cynomolgus Monkeys of AVI-4658, a Phosphorodiamidate Morpholino Oligomer (PMO) Drug for the Treatment of Duchenne Muscular Dystrophy
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Citation:
Int J Toxicol. 2011 May 3. [Epub ahead of print] Epub:
Not Epub Abstract:
AVI-4658 is a phosphorodiamidate morpholino oligomer (PMO) drug designed to restore dystrophin expression in a subset of... Delivery Method:
Intravenous (i.v.) or subcutaneous (s.c.) injection Organism or Cell Type:
monkey, cynomolgus Citation Extract: Sazani P, Van Ness KP, Weller DL, Poage DW, Palyada K, Shrewsbury SB. Repeat-Dose Toxicology Evaluation in Cynomolgus Monkeys of AVI-4658, a Phosphorodiamidate Morpholino Oligomer (PMO) Drug for the Treatment of Duchenne Muscular Dystrophy. Int J Toxicol. 2011 May 3. [Epub ahead of print]. |
Reversal of the cellular phenotype in the premature aging disease Hutchinson-Gilford progeria syndrome
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Citation:
Nat Med. 2005 Apr;11(4):440-5. Epub 2005 Mar 6 Epub:
Not Epub Abstract:
Hutchinson-Gilford progeria syndrome (HGPS) is a childhood premature aging disease caused by a spontaneous point mutation in... Delivery Method:
Electroporation Organism or Cell Type:
cell culture: primary human fibroblast, lymphoblastoid lines Citation Extract: Scaffidi P, Misteli T. Reversal of the cellular phenotype in the premature aging disease Hutchinson-Gilford progeria syndrome. Nat Med. 2005 Apr;11(4):440-5. Epub 2005 Mar 6. |
Safety Pharmacology and Genotoxicity Evaluation of AVI-4658
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Citation:
Int J Toxicol. 2010 Jan 28. [Epub ahead of print] Epub:
Not Epub Abstract:
Duchenne muscular dystrophy (DMD) is caused by dystrophin gene mutations. Restoration of dystrophin by exon skipping was... Organism or Cell Type:
Mouse, cynomolgus monkey Citation Extract: Sazani P, Weller DL, Shrewsbury SB. Safety Pharmacology and Genotoxicity Evaluation of AVI-4658. Int J Toxicol. 2010 Jan 28. [Epub ahead of print]. |