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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12371 scientific papers returned from the database with the search filters currently being used below.

The ascidian Mesp gene specifies heart precursor cells

Authors:
Satou Y, Imai KS, Satoh N
Citation:
Development. 2004 Jun;131(11):2533-41. Epub 2004 Apr 28.
Epub:
Not Epub
Abstract:
Understanding the molecular basis of heart development is an important research area, because malformation of the...
Delivery Method:
Microinjection
Organism or Cell Type:
Ciona savignyi
Citation Extract:
Satou Y, Imai KS, Satoh N. The ascidian Mesp gene specifies heart precursor cells. Development. 2004 Jun;131(11):2533-41. Epub 2004 Apr 28..

The opposing homeobox genes Goosecoid and Vent1/2 self-regulate Xenopus patterning

Authors:
Sander V, Reversade B, De Robertis EM
Citation:
EMBO J. 2007 Jun 20;26(12):2955-65. Epub 2007 May 24.
Epub:
Not Epub
Abstract:
We present a loss-of-function study using antisense morpholino (MO) reagents for the organizer-specific gene Goosecoid (Gsc)...
Organism or Cell Type:
Xenopus
Citation Extract:
Sander V, Reversade B, De Robertis EM. The opposing homeobox genes Goosecoid and Vent1/2 self-regulate Xenopus patterning. EMBO J. 2007 Jun 20;26(12):2955-65. Epub 2007 May 24..

Traf2- and Nck-interacting kinase is essential for canonical Wnt signaling in Xenopus axis formation

Authors:
Satow R, Shitashige M, Jigami T, Honda K, Ono M, Hirohashi S, Yamada T
Citation:
J Biol Chem. 2010 Jun 21. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Wnt signaling pathways play important roles in various stages of developmental events and several aspects of adult homeostasis...
Organism or Cell Type:
Xenopus
Citation Extract:
Satow R, Shitashige M, Jigami T, Honda K, Ono M, Hirohashi S, Yamada T. Traf2- and Nck-interacting kinase is essential for canonical Wnt signaling in Xenopus axis formation. J Biol Chem. 2010 Jun 21. [Epub ahead of print].

Transposon-mediated insertional mutagenesis revealed the functions of animal cellulose synthase in the ascidian Ciona intestinalis

Authors:
Sasakura Y, Nakashima K, Awazu S, Matsuoka T, Nakayama A, Azuma J, Satoh N
Citation:
Proc Natl Acad Sci U S A. 2005 Oct 18;102(42):15134-9. Epub 2005 Oct 7
Epub:
Not Epub
Abstract:
Tunicates are the only animals that perform cellulose biosynthesis. The tunicate gene for cellulose synthase, Ci-CesA, was...
Organism or Cell Type:
Ciona intestinalis
Citation Extract:
Sasakura Y, Nakashima K, Awazu S, Matsuoka T, Nakayama A, Azuma J, Satoh N. Transposon-mediated insertional mutagenesis revealed the functions of animal cellulose synthase in the ascidian Ciona intestinalis. Proc Natl Acad Sci U S A. 2005 Oct 18;102(42):15134-9. Epub 2005 Oct 7.

Zebrafish zic2a patterns the forebrain through modulation of Hedgehog-activated gene expression

Authors:
Sanek NA, Taylor AA, Nyholm MK, Grinblat Y
Citation:
Development. 2009 Nov;136(22):3791-800
Epub:
Not Epub
Abstract:
Holoprosencephaly (HPE) is the most common congenital malformation of the forebrain in human. Several genes with essential...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sanek NA, Taylor AA, Nyholm MK, Grinblat Y. Zebrafish zic2a patterns the forebrain through modulation of Hedgehog-activated gene expression. Development. 2009 Nov;136(22):3791-800.

A combinatorial code of maternal GATA, Ets and beta-catenin-TCF transcription factors specifies and patterns the early ascidian ectoderm

Authors:
Rothbächer U, Bertrand V, Lamy C, Lemaire P
Citation:
Development. 2007 Nov;134(22):4023-32
Epub:
Not Epub
Abstract:
Our understanding of the maternal factors that initiate early chordate development, and of their direct zygotic targets, is...
Organism or Cell Type:
Ciona intestinalis
Citation Extract:
Rothbächer U, Bertrand V, Lamy C, Lemaire P. A combinatorial code of maternal GATA, Ets and beta-catenin-TCF transcription factors specifies and patterns the early ascidian ectoderm. Development. 2007 Nov;134(22):4023-32.

A Framework for the Establishment of a Cnidarian Gene Regulatory Network for “Endomesoderm” Specification: The Inputs of ß-Catenin/TCF Signaling

Authors:
Röttinger E, Dahlin P, Martindale MQ
Citation:
PLoS Genet. 2012;8(12):e1003164. doi:10.1371/journal.pgen.1003164
Epub:
Not Epub
Abstract:
Understanding the functional relationship between intracellular factors and extracellular signals is required for...
Delivery Method:
Microinjection
Organism or Cell Type:
Nematostella vectensis (cnidarian)
Citation Extract:
Röttinger E, Dahlin P, Martindale MQ. A Framework for the Establishment of a Cnidarian Gene Regulatory Network for “Endomesoderm” Specification: The Inputs of ß-Catenin/TCF Signaling. PLoS Genet. 2012;8(12):e1003164. doi:10.1371/journal.pgen.1003164.

A genetic screen in zebrafish identifies the mutants vps18, nf2 and foie gras as models of liver disease.

Authors:
Sadler KC, Amsterdam A, Soroka C, Boyer J, Hopkins N.
Citation:
Development. 2005 Aug;132(15):3561-72. Epub 2005 Jul 6.
Epub:
Not Epub
Abstract:
Hepatomegaly is a sign of many liver disorders. To identify zebrafish mutants to serve as models for hepatic pathologies, we...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sadler KC, Amsterdam A, Soroka C, Boyer J, Hopkins N.. A genetic screen in zebrafish identifies the mutants vps18, nf2 and foie gras as models of liver disease.. Development. 2005 Aug;132(15):3561-72. Epub 2005 Jul 6..

A Key Role for Poly(ADP-Ribose) Polymerase 3 in Ectodermal Specification and Neural Crest Development

Authors:
Rouleau M, Saxena V, Rodrigue A, Paquet ER, Gagnon A, Hendzel MJ, Masson J-Y, Ekker M, Poirier GG
Citation:
PLoS ONE. 2011;6(1):e15834. doi:10.1371/journal.pone.0015834
Epub:
Not Epub
Abstract:
Background The PARP family member poly(ADP-ribose) polymerase 3 (PARP3) is structurally related to the well characterized PARP1...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Rouleau M, Saxena V, Rodrigue A, Paquet ER, Gagnon A, Hendzel MJ, Masson J-Y, Ekker M, Poirier GG. A Key Role for Poly(ADP-Ribose) Polymerase 3 in Ectodermal Specification and Neural Crest Development. PLoS ONE. 2011;6(1):e15834. doi:10.1371/journal.pone.0015834.

A Myc-Slug (Snail2)/Twist regulatory circuit directs vascular development

Authors:
Rodrigues CO, Nerlick ST, White EL, Cleveland JL, King ML
Citation:
Development. 2008 Jun;135(11):1903-11
Epub:
Not Epub
Abstract:
Myc-deficient mice fail to develop normal vascular networks and Myc-deficient embryonic stem cells fail to provoke a tumor...
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Rodrigues CO, Nerlick ST, White EL, Cleveland JL, King ML. A Myc-Slug (Snail2)/Twist regulatory circuit directs vascular development. Development. 2008 Jun;135(11):1903-11.

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