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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12371 scientific papers returned from the database with the search filters currently being used below.

The tbx/bHLH transcription factor mga regulates gata4 and organogenesis

Authors:
Rikin A, Evans T
Citation:
Dev Dyn. 2010 Feb;239(2):535-47. doi: 10.1002/dvdy.22197.
Epub:
Not Epub
Abstract:
The mga gene encodes a unique transcription factor containing both TBOX and bHLHzip DNA-binding domains. Here we describe the...
Organism or Cell Type:
zebrafish
Citation Extract:
Rikin A, Evans T. The tbx/bHLH transcription factor mga regulates gata4 and organogenesis. Dev Dyn. 2010 Feb;239(2):535-47. doi: 10.1002/dvdy.22197..

Use of vivo-morpholinos for control of protein expression in the adult rat brain

Authors:
Reissner KJ, Sartor GC, Vazey EM, Dunn TE, Aston-Jones G, Kalivas PW
Citation:
J Neurosci Meth. 2012 Jan 30;203(2):354-60. doi: 10.1016/j.jneumeth.2011.10.009. Epub 2011 Oct 17
Epub:
Not Epub
Abstract:
Vivo-morpholinos are commercially available morpholino oligomers with a terminal octa-guanidinium dendrimer for enhanced cell-...
Delivery Method:
Injection, intracranial
Organism or Cell Type:
Rat
Citation Extract:
Reissner KJ, Sartor GC, Vazey EM, Dunn TE, Aston-Jones G, Kalivas PW. Use of vivo-morpholinos for control of protein expression in the adult rat brain. J Neurosci Meth. 2012 Jan 30;203(2):354-60. doi: 10.1016/j.jneumeth.2011.10.009. Epub 2011 Oct 17.

VANGL1 rare variants associated with neural tube defects affect convergent extension in zebrafish

Authors:
Reynolds A, McDearmid JR, Lachance S, Marco PD, Merello E, Capra V, Gros P, Drapeau P, Kibar Z
Citation:
Mech Dev. 2010 Jan 2. [Epub ahead of print]
Epub:
Not Epub
Abstract:
In humans, rare non-synonymous variants in the planar cell polarity gene VANGL1 are associated with neural tube defects (NTDs...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Reynolds A, McDearmid JR, Lachance S, Marco PD, Merello E, Capra V, Gros P, Drapeau P, Kibar Z. VANGL1 rare variants associated with neural tube defects affect convergent extension in zebrafish. Mech Dev. 2010 Jan 2. [Epub ahead of print].

Xbves is a regulator of epithelial movement during early Xenopus laevis development

Authors:
Ripley AN, Osler ME, Wright CV, Bader D
Citation:
Proc Natl Acad Sci U S A. 2006 Jan 17;103(3):614-9. Epub 2006 Jan 9.
Epub:
Not Epub
Abstract:
Bves/pop1a is a unique, highly conserved integral membrane protein expressed in embryonic epithelia and striated muscle....
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Ripley AN, Osler ME, Wright CV, Bader D. Xbves is a regulator of epithelial movement during early Xenopus laevis development. Proc Natl Acad Sci U S A. 2006 Jan 17;103(3):614-9. Epub 2006 Jan 9..

Zebrafish usp39 Mutation Leads to rb1 mRNA Splicing Defect and Pituitary Lineage Expansion

Authors:
Ríos Y, Melmed S, Lin S, Liu NA
Citation:
PLoS Genet. 2011 Jan 13;7(1):e1001271
Epub:
Not Epub
Abstract:
Loss of retinoblastoma (Rb) tumor suppressor function is associated with human malignancies. Molecular and genetic mechanisms...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ríos Y, Melmed S, Lin S, Liu NA. Zebrafish usp39 Mutation Leads to rb1 mRNA Splicing Defect and Pituitary Lineage Expansion. PLoS Genet. 2011 Jan 13;7(1):e1001271.

In vivo evaluation of a morpholino antisense oligomer directed against tumor necrosis factor-alpha

Authors:
Qin G, Taylor M, Ning YY, Iversen P, Kobzik L
Citation:
Antisense Nucleic Acid Drug Dev 2000 Feb;10(1):11-6
Epub:
Not Epub
Abstract:
Morpholino antisense oligomers directed against the cytokine tumor necrosis factor (TNF-alpha) can specifically inhibit...
Delivery Method:
in vivo: intranasal
Organism or Cell Type:
BALB/c mice
Citation Extract:
Qin G, Taylor M, Ning YY, Iversen P, Kobzik L. In vivo evaluation of a morpholino antisense oligomer directed against tumor necrosis factor-alpha. Antisense Nucleic Acid Drug Dev 2000 Feb;10(1):11-6.

A gene regulatory network controlling hhex transcription in the anterior endoderm of the organizer

Authors:
Rankin SA, Kormish J, Kofron M, Jegga A, Zorn AM
Citation:
Dev Biol. 2011 Mar 15;351(2):297-310. Epub 2011 Jan 4.
Epub:
Not Epub
Abstract:
The homeobox gene hhex is one of the earliest markers of the anterior endoderm, which gives rise to foregut organs such as the...
Organism or Cell Type:
Xenopus
Citation Extract:
Rankin SA, Kormish J, Kofron M, Jegga A, Zorn AM. A gene regulatory network controlling hhex transcription in the anterior endoderm of the organizer. Dev Biol. 2011 Mar 15;351(2):297-310. Epub 2011 Jan 4..

A non-enzymatic function of 17beta-hydroxysteroid dehydrogenase type 10 is required for mitochondrial integrity and cell survival

Authors:
Rauschenberger K, Schöler K, Sass JO, Sauer S, Djuric Z, Rumig C, Wolf NI, Okun JG, Kölker S, Schwarz H, Fischer C, Grziwa B, Runz H, Nümann A, Shafqat N, Kavanagh KL, Hämmerling G, Wanders RJ, Shield JP, Wendel U, Stern D, Nawroth P, Hoffmann GF, Bartram CR, Arnold B, Bierhaus A, Oppermann U, Steinbeisser H, Zschocke J
Citation:
EMBO Mol Med. 2010 Feb;2(2):51-62
Epub:
Not Epub
Abstract:
Deficiency of the mitochondrial enzyme 2-methyl-3-hydroxybutyryl-CoA dehydrogenase involved in isoleucine metabolism causes an...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Rauschenberger K, Schöler K, Sass JO, Sauer S, Djuric Z, Rumig C, Wolf NI, Okun JG, Kölker S, Schwarz H, Fischer C, Grziwa B, Runz H, Nümann A, Shafqat N, Kavanagh KL, Hämmerling G, Wanders RJ, Shield JP, Wendel U, Stern D, Nawroth P, Hoffmann GF, Bartram CR, Arnold B, Bierhaus A, Oppermann U, Steinbeisser H, Zschocke J. A non-enzymatic function of 17beta-hydroxysteroid dehydrogenase type 10 is required for mitochondrial integrity and cell survival. EMBO Mol Med. 2010 Feb;2(2):51-62.

A novel vertebrate model of Staphylococcus aureus infection reveals phagocyte-dependent resistance of zebrafish to non-host specialized pathogens

Authors:
Prajsnar TK, Cunliffe VT, Foster SJ, Renshaw SA
Citation:
Cell Microbiol. 2008 Aug 18. [Epub ahead of print]
Epub:
Not Epub
Abstract:
With the emergence of multiply resistant Staphylococcus aureus, there is an urgent need to better understand the molecular...
Organism or Cell Type:
zebrafish
Citation Extract:
Prajsnar TK, Cunliffe VT, Foster SJ, Renshaw SA. A novel vertebrate model of Staphylococcus aureus infection reveals phagocyte-dependent resistance of zebrafish to non-host specialized pathogens. Cell Microbiol. 2008 Aug 18. [Epub ahead of print].

A privileged intraphagocyte niche is responsible for disseminated infection of Staphylococcus aureus in a zebrafish model

Authors:
Prajsnar TK, Hamilton R, Garcia-Lara J, McVicker G, Williams A, Boots M, Foster SJ, Renshaw SA
Citation:
Cell Microbiol. 2012 Oct;14(10):1600-19. doi: 10.1111/j.1462-5822.2012.01826.x. Epub 2012 Jul 4
Epub:
Not Epub
Abstract:
The innate immune system is the primary defence against the versatile pathogen, Staphylococcus aureus. How this organism is...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Prajsnar TK, Hamilton R, Garcia-Lara J, McVicker G, Williams A, Boots M, Foster SJ, Renshaw SA. A privileged intraphagocyte niche is responsible for disseminated infection of Staphylococcus aureus in a zebrafish model. Cell Microbiol. 2012 Oct;14(10):1600-19. doi: 10.1111/j.1462-5822.2012.01826.x. Epub 2012 Jul 4.

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