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Morpholino Publication Database
      This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12511 scientific papers returned from the database with the search filters currently being used below.
    
  
      There are 12511 scientific papers returned from the database with the search filters currently being used below.
Microinjection of zebrafish embryos to analyze gene function
|     Citation:      J Vis Exp. 2009 Mar 9;(25). pii: 1115. doi: 10.3791/1115.     Epub:      Not Epub     Abstract:      One of the advantages of studying zebrafish is the ease and speed of manipulating protein levels in the embryo. Morpholinos,...     Delivery Method:      Microinjection     Organism or Cell Type:      zebrafish     Citation Extract:      Rosen JN, Sweeney MF, Mably JD. Microinjection of zebrafish embryos to analyze gene function. J Vis Exp. 2009 Mar 9;(25). pii: 1115. doi: 10.3791/1115.. | 
Miz-1 is required to coordinate the expression of TCRbeta and p53 effector genes at the pre-TCR "beta-selection" checkpoint
|     Citation:      J Immunol. 2011 Sep 15;187(6):2982-92. doi: 10.4049/jimmunol.1101451. Epub 2011 Aug 12. PMID: 21841135     Epub:      Not Epub     Abstract:      Miz-1 is a Broad-complex, Tramtrack and Bric-à-brac/pox virus zinc finger domain (BTB/POZ)-containing protein expressed in...     Citation Extract:      Saba I, Kosan C, Vassen L, Klein-Hitpass L, Möröy T. Miz-1 is required to coordinate the expression of TCRbeta and p53 effector genes at the pre-TCR "beta-selection" checkpoint. J Immunol. 2011 Sep 15;187(6):2982-92. doi: 10.4049/jimmunol.1101451. Epub 2011 Aug 12. PMID: 21841135. | 
Modulation of Tcf3 repressor complex composition regulates cdx4 expression in zebrafish
|     Citation:      EMBO J. 2011 Jun 10;30(14):2894-907. doi: 10.1038/emboj.2011.184     Epub:      Not Epub     Abstract:      The caudal homeobox (cdx) gene family is critical for specification of caudal body formation and erythropoiesis. In zebrafish,...     Delivery Method:      Microinjection     Organism or Cell Type:      zebrafish     Citation Extract:      Ro H, Dawid IB. Modulation of Tcf3 repressor complex composition regulates cdx4 expression in zebrafish. EMBO J. 2011 Jun 10;30(14):2894-907. doi: 10.1038/emboj.2011.184. | 
Mutations in ISPD cause Walker-Warburg syndrome and defective glycosylation of α-dystroglycan
|     Citation:      Nat Genet. 2012 Apr 22. doi: 10.1038/ng.2253. [Epub ahead of print]     Epub:      Not Epub     Abstract:      Walker-Warburg syndrome (WWS) is an autosomal recessive multisystem disorder characterized by complex eye and brain...     Delivery Method:      Microinjection     Organism or Cell Type:      zebrafish     Citation Extract:      Roscioli T, Kamsteeg EJ, Buysse K, Maystadt I, van Reeuwijk J, van den Elzen C, van Beusekom E, Riemersma M, Pfundt R, Vissers LE, Schraders M, Altunoglu U, Buckley MF, Brunner HG, Grisart B, Zhou H, Veltman JA, Gilissen C, Mancini GM, Delrée P, Willemsen MA, Ramadža DP, Chitayat D, Bennett C, Sheridan E, Peeters EA, Tan-Sindhunata GM, de Die-Smulders CE, Devriendt K, Kayserili H, El-Hashash OA, Stemple DL, Lefeber DJ, Lin YY, van Bokhoven H. Mutations in ISPD cause Walker-Warburg syndrome and defective glycosylation of α-dystroglycan. Nat Genet. 2012 Apr 22. doi: 10.1038/ng.2253. [Epub ahead of print]. | 
Mutations in lectin complement pathway genes COLEC11 and MASP1 cause 3MC syndrome
|     Citation:      Nat Genet. 2011 Jan 23. [Epub ahead of print]     Epub:      Not Epub     Abstract:      3MC syndrome has been proposed as a unifying term encompassing the overlapping Carnevale, Mingarelli, Malpuech and Michels...     Organism or Cell Type:      zebrafish     Citation Extract:      Rooryck C, Diaz-Font A, Osborn DP, Chabchoub E, Hernandez-Hernandez V, Shamseldin H, Kenny J, Waters A, Jenkins D, Kaissi AA, Leal GF, Dallapiccola B, Carnevale F, Bitner-Glindzicz M, Lees M, Hennekam R, Stanier P, Burns AJ, Peeters H, Alkuraya FS, Beales. Mutations in lectin complement pathway genes COLEC11 and MASP1 cause 3MC syndrome. Nat Genet. 2011 Jan 23. [Epub ahead of print]. | 
Nemo-like kinase (NLK) acts downstream of Notch/Delta signalling to downregulate TCF during mesoderm induction in the sea urchin embryo
|     Citation:      Development. 2006 Nov;133(21):4341-53     Epub:      Not Epub     Abstract:      Studies in Caenorhabditis elegans and vertebrates have established that the MAP kinase-related protein NLK counteracts Wnt...     Organism or Cell Type:      Sea urchin, Paracentrotus lividus     Citation Extract:      Röttinger E, Croce J, Lhomond G, Besnardeau L, Gache C, Lepage T. Nemo-like kinase (NLK) acts downstream of Notch/Delta signalling to downregulate TCF during mesoderm induction in the sea urchin embryo. Development. 2006 Nov;133(21):4341-53. | 
Nodal signalling imposes left-right asymmetry upon neurogenesis in the habenular nuclei
|     Citation:      Development. 2009 May;136(9):1549-57     Epub:      Not Epub     Abstract:      The habenulae are evolutionarily conserved bilateral nuclei in the epithalamus that relay input from the forebrain to the...     Delivery Method:      Microinjection     Organism or Cell Type:      zebrafish     Citation Extract:      Roussigné M, Bianco IH, Wilson SW, Blader P. Nodal signalling imposes left-right asymmetry upon neurogenesis in the habenular nuclei. Development. 2009 May;136(9):1549-57. | 
p53 activation by knockdown technologies
|     Citation:      PLoS Genet. 2007 May 25;3(5):e78. Epub 2007 Apr 10     Epub:      Not Epub     Abstract:      Morpholino phosphorodiamidate antisense oligonucleotides (MOs) and short interfering RNAs (siRNAs) are commonly used platforms...     Delivery Method:      Microinjection     Organism or Cell Type:      zebrafish     Citation Extract:      Robu ME, Larson JD, Nasevicius A, Beiraghi S, Brenner C, Farber SA, Ekker SC. p53 activation by knockdown technologies. PLoS Genet. 2007 May 25;3(5):e78. Epub 2007 Apr 10. | 
Paladin is an antiphosphatase that regulates neural crest cell formation and migration
|     Citation:      Dev Biol. 2012 Aug 24. [Epub ahead of print]     Epub:      Not Epub     Abstract:      Although a network of transcription factors that specifies neural crest identity in the ectoderm has been defined, expression...     Delivery Method:      Electroporation     Organism or Cell Type:      chick (Gallus gallus)     Citation Extract:      Roffers-Agarwal J, Hutt KJ, Gammill LS. Paladin is an antiphosphatase that regulates neural crest cell formation and migration. Dev Biol. 2012 Aug 24. [Epub ahead of print]. | 
Regulation of actin cytoskeleton architecture by Eps8 and Abi1
|     Citation:      BMC Cell Biol. 2005 Oct 14;6:36     Epub:      Not Epub     Abstract:      BACKGROUND: The actin cytoskeleton participates in many fundamental processes including the regulation of cell shape, motility...     Delivery Method:      Microinjection     Organism or Cell Type:      Xenopus laevis     Citation Extract:      Roffers-Agarwal J, Xanthos JB, Miller JR. Regulation of actin cytoskeleton architecture by Eps8 and Abi1. BMC Cell Biol. 2005 Oct 14;6:36. | 
