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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

Combinatorial function of ETS transcription factors in the developing vasculature

Authors:
Pham VN, Lawson ND, Mugford JW, Dye L, Castranova D, Lo B, Weinstein BM
Citation:
Dev Biol. 2007 Mar 15;303(2):772-83. Epub 2006 Oct 25.
Epub:
Not Epub
Abstract:
Members of the ETS family of transcription factors are among the first genes expressed in the developing vasculature, but loss-...
Organism or Cell Type:
zebrafish
Citation Extract:
Pham VN, Lawson ND, Mugford JW, Dye L, Castranova D, Lo B, Weinstein BM. Combinatorial function of ETS transcription factors in the developing vasculature. Dev Biol. 2007 Mar 15;303(2):772-83. Epub 2006 Oct 25..

Common genetic control of haemangioblast and cardiac development in zebrafish

Authors:
Peterkin T, Gibson A, Patient R
Citation:
Development. 2009 May;136(9):1465-74. Epub 2009 Mar 18
Epub:
Not Epub
Abstract:
Over the past few years it has become clear that over half of the mammalian heart derives from outside the heart field as...
Organism or Cell Type:
zebrafish
Citation Extract:
Peterkin T, Gibson A, Patient R. Common genetic control of haemangioblast and cardiac development in zebrafish. Development. 2009 May;136(9):1465-74. Epub 2009 Mar 18.

Comparative analysis of antisense oligonucleotide sequences targeting exon 53 of the human DMD gene: Implications for future clinical trials

Authors:
Popplewell LJ, Adkin C, Arechavala-Gomeza V, Aartsma-Rus A, de Winter CL, Wilton SD, Morgan JE, Muntoni F, Graham IR, Dickson G
Citation:
Neuromuscul Disord. 2010 Jan 13. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Duchenne muscular dystrophy (DMD) is caused by the lack of functional dystrophin protein, most commonly as a result of a range...
Link:
https://www.nmd-journal.com/article/S0960-8966(09)00666-X/abstract
Delivery Method:
Electroporation (Amaxa)
Organism or Cell Type:
mouse expressing human dystrophin, cultured DMD cells
Citation Extract:
Popplewell LJ, Adkin C, Arechavala-Gomeza V, Aartsma-Rus A, de Winter CL, Wilton SD, Morgan JE, Muntoni F, Graham IR, Dickson G. Comparative analysis of antisense oligonucleotide sequences targeting exon 53 of the human DMD gene: Implications for future clinical trials. Neuromuscul Disord. 2010 Jan 13. [Epub ahead of print].

Conservation of the global sex determination gene tra-1 in distantly related nematodes

Authors:
Pires-DaSilva A, Sommer RJ
Citation:
Genes Dev. 2004 May 15;18(10):1198-208
Epub:
Not Epub
Abstract:
Sex determination has long intrigued evolutionists, geneticists, and developmental biologists in a similar way. Substantial...
Delivery Method:
Microinjection
Organism or Cell Type:
Nematodes: Pristionchus pacificus and Caenorhabditis elegans
Citation Extract:
Pires-DaSilva A, Sommer RJ. Conservation of the global sex determination gene tra-1 in distantly related nematodes. Genes Dev. 2004 May 15;18(10):1198-208.

Conserved and divergent functions of Nfix in skeletal muscle development during vertebrate evolution

Authors:
Pistocchi A, Gaudenzi G, Foglia E, Monteverde S, Moreno-Fortuny A, Pianca A, Cossu G, Cotelli F, Messina G
Citation:
Development. 2013;140:1528-36. doi:10.1242/dev.076315
Epub:
Not Epub
Abstract:
During mouse skeletal muscle development, the Nfix gene has a pivotal role in regulating fetal-specific transcription....
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Pistocchi A, Gaudenzi G, Foglia E, Monteverde S, Moreno-Fortuny A, Pianca A, Cossu G, Cotelli F, Messina G. Conserved and divergent functions of Nfix in skeletal muscle development during vertebrate evolution. Development. 2013;140:1528-36. doi:10.1242/dev.076315.

CRIM1 Complexes with ß-catenin and Cadherins, Stabilizes Cell-Cell Junctions and Is Critical for Neural Morphogenesis

Authors:
Ponferrada VG, Fan J, Vallance JE, Hu S, Mamedova A, Rankin SA, Kofron M, Zorn AM, Hegde RS, Lang RA
Citation:
PLoS ONE. 2012;7(3): e32635. doi:10.1371/journal.pone.0032635
Epub:
Not Epub
Abstract:
In multicellular organisms, morphogenesis is a highly coordinated process that requires dynamically regulated adhesion between...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Ponferrada VG, Fan J, Vallance JE, Hu S, Mamedova A, Rankin SA, Kofron M, Zorn AM, Hegde RS, Lang RA. CRIM1 Complexes with ß-catenin and Cadherins, Stabilizes Cell-Cell Junctions and Is Critical for Neural Morphogenesis. PLoS ONE. 2012;7(3): e32635. doi:10.1371/journal.pone.0032635.

Crucial role of zebrafish prox1 in hypothalamic catecholaminergic neurons development

Authors:
Pistocchi A, Gaudenzi G, Carra S, Bresciani E, Del Giacco L, Cotelli F
Citation:
BMC Dev Biol. 2008 Mar 10;8:27
Epub:
Not Epub
Abstract:
BACKGROUND: Prox1, the vertebrate homolog of prospero in Drosophila melanogaster, is a divergent homeogene that regulates cell...
Organism or Cell Type:
zebrafish
Citation Extract:
Pistocchi A, Gaudenzi G, Carra S, Bresciani E, Del Giacco L, Cotelli F. Crucial role of zebrafish prox1 in hypothalamic catecholaminergic neurons development. BMC Dev Biol. 2008 Mar 10;8:27.

CytLEK1 is a regulator of plasma membrane recycling through its interaction with SNAP-25

Authors:
Pooley RD, Reddy S, Soukoulis V, Roland JT, Goldenring JR, Bader DM
Citation:
Mol Biol Cell. 2006 Jul;17(7):3176-86. Epub 2006 May 3
Epub:
Not Epub
Abstract:
SNAP-25 is a component of the SNARE complex that is involved in membrane docking and fusion. Using a yeast two-hybrid screen,...
Organism or Cell Type:
cell culture: NIH-3T3 cells
Citation Extract:
Pooley RD, Reddy S, Soukoulis V, Roland JT, Goldenring JR, Bader DM. CytLEK1 is a regulator of plasma membrane recycling through its interaction with SNAP-25. Mol Biol Cell. 2006 Jul;17(7):3176-86. Epub 2006 May 3.

Delivery of NADPH-Cytochrome P450 Reductase Antisense Oligos Using Avidin-Biotin Approach

Authors:
Pillai VC, Yesudas R, Shaik IH, Thekkumkara TJ, Bickel U, Srivenugopal KS, Mehvar R
Citation:
Bioconjug Chem. 2010 Jan 11. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Although avidin-mediated intracellular delivery of oligonucleotides or proteins has been shown before, the efficacy studies are...
Delivery Method:
Avadin-biotin system, Endo-Porter
Organism or Cell Type:
Rat liver epithelial cells
Citation Extract:
Pillai VC, Yesudas R, Shaik IH, Thekkumkara TJ, Bickel U, Srivenugopal KS, Mehvar R. Delivery of NADPH-Cytochrome P450 Reductase Antisense Oligos Using Avidin-Biotin Approach. Bioconjug Chem. 2010 Jan 11. [Epub ahead of print].

Design of Phosphorodiamidate Morpholino Oligomers (PMOs) for the Induction of Exon Skipping of the Human DMD Gene

Authors:
Popplewell LJ, Trollet C, Dickson G, Graham IR
Citation:
Mol Ther. 2009 Jan 13. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Duchenne muscular dystrophy (DMD) is caused by out-of-frame mutations of the human DMD gene. Antisense oligonucleotides (AOs)...
Link:
https://www.sciencedirect.com/science/article/pii/S152500161631543X
Organism or Cell Type:
cell culture: human skeletal muscle
Citation Extract:
Popplewell LJ, Trollet C, Dickson G, Graham IR. Design of Phosphorodiamidate Morpholino Oligomers (PMOs) for the Induction of Exon Skipping of the Human DMD Gene. Mol Ther. 2009 Jan 13. [Epub ahead of print] .

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