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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

Pax2/8 proteins coordinate sequential induction of otic and epibranchial placodes through differential regulation of foxi1, sox3 and fgf24

Authors:
Padanad MS, Riley BB
Citation:
Dev Biol. 2011 Mar 1;351(1):90-8. Epub 2011 Jan 4
Epub:
Not Epub
Abstract:
Vertebrate cranial placodes contribute vitally to development of sensory structures of the head. Amongst posterior placodes,...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Padanad MS, Riley BB. Pax2/8 proteins coordinate sequential induction of otic and epibranchial placodes through differential regulation of foxi1, sox3 and fgf24. Dev Biol. 2011 Mar 1;351(1):90-8. Epub 2011 Jan 4.

Peptide Conjugated Phosphorodiamidate Morpholino Oligomers Increase Survival of Mice Challenged with Ames Bacillus anthracis

Authors:
Panchal RG, Geller BL, Mellbye B, Lane D, Iversen PL, Bavari S
Citation:
Nucleic Acid Therapeutics. 2012;[Epub ahead of print] doi:10.1089/nat.2012.0362
Epub:
Not Epub
Abstract:
Targeting bacterial essential genes using antisense phosphorodiamidate morpholino oligomers (PMOs) represents an important...
Delivery Method:
peptide-coupled
Organism or Cell Type:
Bacillus anthracis
Citation Extract:
Panchal RG, Geller BL, Mellbye B, Lane D, Iversen PL, Bavari S. Peptide Conjugated Phosphorodiamidate Morpholino Oligomers Increase Survival of Mice Challenged with Ames Bacillus anthracis. Nucleic Acid Therapeutics. 2012;[Epub ahead of print] doi:10.1089/nat.2012.0362.

Peptide-conjugated morpholino oligomers inhibit porcine reproductive and respiratory syndrome virus replication

Authors:
Patel D, Opriessnig T, Stein DA, Halbur PG, Meng XJ, Iversen PL, Zhang YJ
Citation:
Antiviral Res. 2008 Feb;77(2):95-107. Epub 2007 Oct 4
Epub:
Not Epub
Abstract:
Porcine reproductive and respiratory syndrome (PRRS) has been devastating the global swine industry for more than a decade, and...
Delivery Method:
peptide-coupled
Organism or Cell Type:
Porcine reproductive and resporatory syndrome virus (PRRSV) in cell cultures
Citation Extract:
Patel D, Opriessnig T, Stein DA, Halbur PG, Meng XJ, Iversen PL, Zhang YJ. Peptide-conjugated morpholino oligomers inhibit porcine reproductive and respiratory syndrome virus replication. Antiviral Res. 2008 Feb;77(2):95-107. Epub 2007 Oct 4.

Phosphorylation of p53 is regulated by TPX2-Aurora A in xenopus oocytes

Authors:
Pascreau G, Eckerdt F, Lewellyn AL, Prigent C, Maller JL
Citation:
J Biol Chem. 2009 Feb 27;284(9):5497-505. Epub 2009 Jan 2
Epub:
Not Epub
Abstract:
p53 is an important tumor suppressor regulating the cell cycle at multiple stages in higher vertebrates. The p53 gene is...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Pascreau G, Eckerdt F, Lewellyn AL, Prigent C, Maller JL. Phosphorylation of p53 is regulated by TPX2-Aurora A in xenopus oocytes. J Biol Chem. 2009 Feb 27;284(9):5497-505. Epub 2009 Jan 2.

Planar cell polarity signalling regulates cell adhesion properties in progenitors of the zebrafish laterality organ

Authors:
Oteiza P, Köppen M, Krieg M, Pulgar E, Farias C, Melo C, Preibisch S, Müller D, Tada M, Hartel S, Heisenberg CP, Concha ML
Citation:
Development. 2010 Oct;137(20):3459-68. Epub 2010 Sep 15
Epub:
Not Epub
Abstract:
Organ formation requires the precise assembly of progenitor cells into a functional multicellular structure. Mechanical forces...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Oteiza P, Köppen M, Krieg M, Pulgar E, Farias C, Melo C, Preibisch S, Müller D, Tada M, Hartel S, Heisenberg CP, Concha ML. Planar cell polarity signalling regulates cell adhesion properties in progenitors of the zebrafish laterality organ. Development. 2010 Oct;137(20):3459-68. Epub 2010 Sep 15.

Potential role of bone morphogenetic protein-15 in zebrafish follicle development and oocyte maturation

Authors:
Peng C, Clelland E, Tan Q
Citation:
Comp Biochem Physiol A Mol Integr Physiol. 2008 Oct 12. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Bone morphogenetic protein (BMP)-15 is a member of the transforming growth factor beta (TGF-beta) superfamily and is closely...
Organism or Cell Type:
zebrafish
Citation Extract:
Peng C, Clelland E, Tan Q. Potential role of bone morphogenetic protein-15 in zebrafish follicle development and oocyte maturation. Comp Biochem Physiol A Mol Integr Physiol. 2008 Oct 12. [Epub ahead of print].

Protein kinase Cgamma is a signaling molecule required for the developmental speeding of alpha-amino-3-hydroxyl-5-methyl-4-isoxazole-propionate receptor kinetics

Authors:
Patten SA, Roy B, Cunningham ME, Stafford JL, Ali DW
Citation:
Eur J Neurosci. 2010 May;31(9):1561-73
Epub:
Not Epub
Abstract:
A key step in the maturation of glutamate synapses is the developmental speeding of alpha-amino-3-hydroxyl-5-methyl-4-isoxazole...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Patten SA, Roy B, Cunningham ME, Stafford JL, Ali DW. Protein kinase Cgamma is a signaling molecule required for the developmental speeding of alpha-amino-3-hydroxyl-5-methyl-4-isoxazole-propionate receptor kinetics. Eur J Neurosci. 2010 May;31(9):1561-73.

Pseudoexon exclusion by antisense therapy in methylmalonic aciduria (MMAuria)

Authors:
Pérez B, Rincón A, Jorge-Finnigan A, Richard E, Merinero B, Ugarte M, Desviat LR
Citation:
Hum Mutat. 2009 Dec;30(12):1676-82
Epub:
Not Epub
Abstract:
Development of pseudoexon exclusion therapies by antisense modification of pre-mRNA splicing represents a type of personalized...
Delivery Method:
Vivo-Morpholinos and seperately Endo-Porter & bare Morpholinos
Organism or Cell Type:
cell culture: human patient primary fibroblasts
Citation Extract:
Pérez B, Rincón A, Jorge-Finnigan A, Richard E, Merinero B, Ugarte M, Desviat LR. Pseudoexon exclusion by antisense therapy in methylmalonic aciduria (MMAuria). Hum Mutat. 2009 Dec;30(12):1676-82.

PTK7/Otk interacts with Wnts and inhibits canonical Wnt signalling

Authors:
Peradziryi H, Kaplan NA, Podleschny M, Liu X, Wehner P, Borchers A, Tolwinski NS
Citation:
EMBO J. 2011 Jul 19;30(18):3729-40. doi: 10.1038/emboj.2011.236
Epub:
Not Epub
Abstract:
Wnt signalling is an evolutionarily conserved pathway that directs cell-fate determination and morphogenesis during metazoan...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Peradziryi H, Kaplan NA, Podleschny M, Liu X, Wehner P, Borchers A, Tolwinski NS. PTK7/Otk interacts with Wnts and inhibits canonical Wnt signalling. EMBO J. 2011 Jul 19;30(18):3729-40. doi: 10.1038/emboj.2011.236.

Pur alpha and Sp8 as opposing regulators of neural gata2 expression

Authors:
Penberthy WT, Zhao C, Zhang Y, Jessen JR, Yang Z, Bricaud O, Collazo A, Meng A, Lin S
Citation:
Dev Biol. 2004 Nov 1;275(1):225-34
Epub:
Not Epub
Abstract:
Gata2 is an essential hematopoietic transcriptional factor that is also expressed prominently in the nervous system. The early...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Penberthy WT, Zhao C, Zhang Y, Jessen JR, Yang Z, Bricaud O, Collazo A, Meng A, Lin S. Pur alpha and Sp8 as opposing regulators of neural gata2 expression. Dev Biol. 2004 Nov 1;275(1):225-34.

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