You are here
Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
Gene Knockdowns in Adult Animals: PPMOs and Vivo-Morpholinos
|
Citation:
Molecules. 2009 Mar 25;14(3):1304-23 Epub:
Not Epub Abstract:
Antisense molecules do not readily cross cell membranes. This has limited the use of antisense to systems where techniques have... Citation Extract: Moulton JD, Jiang S. Gene Knockdowns in Adult Animals: PPMOs and Vivo-Morpholinos. Molecules. 2009 Mar 25;14(3):1304-23. |
Glucocorticoid Receptor Signaling Is Essential for Mesoderm Formation and Muscle Development in Zebrafish
|
Citation:
Endocrinology. 2011;[Epub ahead of print] doi:10.1210/en.2011-1559 Epub:
Not Epub Abstract:
Glucocorticoid receptor (GR) signaling is thought to play a key role in embryogenesis, but its specific developmental effects... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Nesan D, Kamkar M, Burrows J, Scott IC, Marsden M, Vijayan MM. Glucocorticoid Receptor Signaling Is Essential for Mesoderm Formation and Muscle Development in Zebrafish. Endocrinology. 2011;[Epub ahead of print] doi:10.1210/en.2011-1559 . |
Guidance of mesoderm cell migration in the Xenopus gastrula requires PDGF signaling
|
Citation:
Development. 2004 Jun;131(11):2727-36. Epub 2004 May 5 Epub:
Not Epub Abstract:
In vertebrates, PDGFA and its receptor, PDGFRalpha, are expressed in the early embryo. Impairing their function causes an array... Organism or Cell Type:
Xenopus Citation Extract: Nagel M, Tahinci E, Symes K, Winklbauer R. Guidance of mesoderm cell migration in the Xenopus gastrula requires PDGF signaling. Development. 2004 Jun;131(11):2727-36. Epub 2004 May 5. |
Hes6 Is Required for the Neurogenic Activity of Neurogenin and NeuroD
|
Citation:
PLoS ONE. 2011;6(11):e27880. doi:10.1371/journal.pone.0027880 Epub:
Not Epub Abstract:
In the embryonic neural plate, a subset of precursor cells with neurogenic potential differentiates into neurons. This process... Delivery Method:
Microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Murai K, Philpott A, Jones PH. Hes6 Is Required for the Neurogenic Activity of Neurogenin and NeuroD. PLoS ONE. 2011;6(11):e27880. doi:10.1371/journal.pone.0027880. |
HIF-1alpha signaling upstream of Nkx2.5 is required for cardiac development in xenopus
|
Citation:
J Biol Chem. 2008 Apr 25;283(17):11841-9. Epub 2008 Feb 25. Epub:
Not Epub Abstract:
HIF-1alpha is originally identified as a transcription factor that activates gene expression in response to hypoxia. In... Delivery Method:
Microinjection Organism or Cell Type:
Xenopus Citation Extract: Nagao K, Taniyama Y, Kietzmann T, Doi T, Komuro I, Morishita R. HIF-1alpha signaling upstream of Nkx2.5 is required for cardiac development in xenopus. J Biol Chem. 2008 Apr 25;283(17):11841-9. Epub 2008 Feb 25.. |
Hippo signaling components, Mst1 and Mst2, act as a switch between self-renewal and differentiation in Xenopus hematopoietic and endothelial progenitors
|
Citation:
Int J Dev Biol. 2013;57(5):407-14. doi: 10.1387/ijdb.130010st. Epub:
Not Epub Abstract:
Hippo signaling is a conserved pathway that regulates cell proliferation and organ size control. Mst1 and Mst2 were identified... Delivery Method:
Microinjection Organism or Cell Type:
Xenopus tropicalis Citation Extract: Nejigane S, Takahashi S, Haramoto Y, Michiue T, Asashima M. Hippo signaling components, Mst1 and Mst2, act as a switch between self-renewal and differentiation in Xenopus hematopoietic and endothelial progenitors. Int J Dev Biol. 2013;57(5):407-14. doi: 10.1387/ijdb.130010st.. |
Identification and angiogenic role of the novel tumor endothelial marker CLEC14A
|
Citation:
Oncogene. 2012 Jan 19;31(3):293-305. doi: 10.1038/onc.2011.233. Epub 2011 Jun 27 Epub:
Not Epub Abstract:
Tumor endothelial markers (TEMs) that are highly expressed in human tumor vasculature compared with vasculature in normal... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Mura M, Swain RK, Zhuang X, Vorschmitt H, Reynolds G, Durant S, Beesley JF, Herbert JM, Sheldon H, Andre M, Sanderson S, Glen K, Luu NT, McGettrick HM, Antczak P, Falciani F, Nash GB, Nagy ZS, Bicknell R. Identification and angiogenic role of the novel tumor endothelial marker CLEC14A. Oncogene. 2012 Jan 19;31(3):293-305. doi: 10.1038/onc.2011.233. Epub 2011 Jun 27. |
Identification and characterization of Veph, a novel gene encoding a PH domain-containing protein expressed in the developing central nervous system of vertebrates
|
Citation:
Biochimie. 2004 Aug;86(8):523-31 Epub:
Not Epub Abstract:
We isolated Veph, a novel gene encoding a pleckstrin homology (PH) domain-containing protein from a mouse. Veph was strongly... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Muto E, Tabata Y, Taneda T, Aoki Y, Muto A, Arai K, Watanabe S. Identification and characterization of Veph, a novel gene encoding a PH domain-containing protein expressed in the developing central nervous system of vertebrates. Biochimie. 2004 Aug;86(8):523-31. |
In vitro oocyte culture-based manipulation of zebrafish maternal genes
|
Citation:
Dev Dyn. 2012 Oct 16. doi: 10.1002/dvdy.23894. [Epub ahead of print] Epub:
Not Epub Abstract:
In animals, females deposit gene products into developing oocytes, which drive early cellular events in embryos immediately... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Nair S, Lindeman RE, Pelegri F. In vitro oocyte culture-based manipulation of zebrafish maternal genes. Dev Dyn. 2012 Oct 16. doi: 10.1002/dvdy.23894. [Epub ahead of print]. |
In Vivo Modeling of the Morbid Human Genome using Danio rerio
|
Citation:
J Vis Exp. 2013;(78):e50338. doi:10.3791/50338 Epub:
Not Epub Abstract:
Here, we present methods for the development of assays to query potentially clinically significant nonsynonymous changes using... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Niederriter AR, Davis EE, Golzio C, Oh EC, Tsai IC, Katsanis N. In Vivo Modeling of the Morbid Human Genome using Danio rerio. J Vis Exp. 2013;(78):e50338. doi:10.3791/50338. |