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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12067 scientific papers returned from the database with the search filters currently being used below.

Essential roles of G{alpha}12/13 signaling in distinct cell behaviors driving zebrafish convergence and extension gastrulation movements

Authors:
Lin F, Sepich DS, Chen S, Topczewski J, Yin C, Solnica-Krezel L, Hamm H
Citation:
J Cell Biol. 2005 Jun 6;169(5):777-87.
Epub:
Not Epub
Abstract:
Galpha(12/13) have been implicated in numerous cellular processes, however, their roles in vertebrate gastrulation are largely...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lin F, Sepich DS, Chen S, Topczewski J, Yin C, Solnica-Krezel L, Hamm H. Essential roles of G{alpha}12/13 signaling in distinct cell behaviors driving zebrafish convergence and extension gastrulation movements. J Cell Biol. 2005 Jun 6;169(5):777-87..

Fgf3 and Fgf8 dependent and independent transcription factors are required for otic placode specification

Authors:
Liu D, Chu H, Maves L, Yan YL, Morcos PA, Postlethwait JH, Westerfield M
Citation:
Development. 2003 May;130(10):2213-24
Epub:
Not Epub
Abstract:
The vertebrate inner ear develops from the otic placode, an ectodermal thickening that forms adjacent to the presumptive...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Liu D, Chu H, Maves L, Yan YL, Morcos PA, Postlethwait JH, Westerfield M. Fgf3 and Fgf8 dependent and independent transcription factors are required for otic placode specification. Development. 2003 May;130(10):2213-24.

Fibroblast Growth Factor Receptor 2c Signaling Is Required for Intestinal Cell Differentiation in Zebrafish

Authors:
Liu D-W, Tsai S-M, Lin B-F, Jiang Y-J, Wang W-P
Citation:
PLoS ONE. 2013;8(3):e58310. doi:10.1371/journal.pone.0058310
Epub:
Not Epub
Abstract:
Background There are four cell lineages derived from intestinal stem cells that are located at the crypt and villus in the...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Liu D-W, Tsai S-M, Lin B-F, Jiang Y-J, Wang W-P. Fibroblast Growth Factor Receptor 2c Signaling Is Required for Intestinal Cell Differentiation in Zebrafish. PLoS ONE. 2013;8(3):e58310. doi:10.1371/journal.pone.0058310.

Fli1 Acts at the Top of the Transcriptional Network Driving Blood and Endothelial Development

Authors:
Liu F, Walmsley M, Rodaway A, Patient R
Citation:
Current Biology 2008 Aug 26;18:1234-1240
Epub:
Not Epub
Abstract:
Blood and endothelium arise in close association during development, possibly from a common precursor, the hemangioblast. Genes...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus and zebrafish
Citation Extract:
Liu F, Walmsley M, Rodaway A, Patient R. Fli1 Acts at the Top of the Transcriptional Network Driving Blood and Endothelial Development. Current Biology 2008 Aug 26;18:1234-1240.

Further investigations of morpholino pretargeting in mice-establishing quantitative relations in tumor

Authors:
Liu G, He J, Dou S, Gupta S, Rusckowski M, Hnatowich DJ
Citation:
Eur J Nucl Med Mol Imaging. 2005 Sep;32(9):1115-23.
Epub:
Not Epub
Abstract:
PURPOSE: This laboratory has previously published on phosphorodiamidate morpholino (MORF) pretargeting of tumor in which an...
Delivery Method:
in vivo: injection
Organism or Cell Type:
mice
Citation Extract:
Liu G, He J, Dou S, Gupta S, Rusckowski M, Hnatowich DJ. Further investigations of morpholino pretargeting in mice-establishing quantitative relations in tumor. Eur J Nucl Med Mol Imaging. 2005 Sep;32(9):1115-23..

Galpha12/13 regulate epiboly by inhibiting E-cadherin activity and modulating the actin cytoskeleton

Authors:
Lin F, Chen S, Sepich DS, Panizzi JR, Clendenon SG, Marrs JA, Hamm HE, Solnica-Krezel L
Citation:
J Cell Biol. 2009 Mar 23;184(6):909-21
Epub:
Not Epub
Abstract:
Epiboly spreads and thins the blastoderm over the yolk cell during zebrafish gastrulation, and involves coordinated movements...
Organism or Cell Type:
zebrafish
Citation Extract:
Lin F, Chen S, Sepich DS, Panizzi JR, Clendenon SG, Marrs JA, Hamm HE, Solnica-Krezel L. Galpha12/13 regulate epiboly by inhibiting E-cadherin activity and modulating the actin cytoskeleton. J Cell Biol. 2009 Mar 23;184(6):909-21.

Geminin cooperates with Polycomb to restrain multi-lineage commitment in the early embryo

Authors:
Lim JW, Hummert P, Mills JC, Kroll KL
Citation:
Development. 2011 Jan;138(1):33-44. Epub 2010 Nov 23
Epub:
Not Epub
Abstract:
Transient maintenance of a pluripotent embryonic cell population followed by the onset of multi-lineage commitment is a...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Lim JW, Hummert P, Mills JC, Kroll KL. Geminin cooperates with Polycomb to restrain multi-lineage commitment in the early embryo. Development. 2011 Jan;138(1):33-44. Epub 2010 Nov 23.

Genetic Association for Renal Traits among Participants of African Ancestry Reveals New Loci for Renal Function

Authors:
Liu CT, Garnaas MK, Tin A, Kottgen A, Franceschini N, Peralta CA, de Boer IH, Lu X, Atkinson E, Ding J, Nalls M, Shriner D, Coresh J, Kutlar A, Bibbins-Domingo K, Siscovick D, Akylbekova E, Wyatt S, Astor B, Mychaleckjy J, Man Li M, Reilly MP, Townsend RR, Adeyemo A, Zonderman AB, de Andrade M, Turner ST, Mosley TH, Harris TB, The CKDGen Consortium, Rotimi CN, Liu Y, Kardia SLR, Evans MK, Shlipak MG, Kramer H, Flessner MF, Dreisbach AW, Goessling W, Cupples LA, Kao WL, Fox CS
Citation:
PLoS Genet. 2011;7(9): e1002264. doi:10.1371/journal.pgen.1002264
Epub:
Not Epub
Abstract:
Chronic kidney disease (CKD) is an increasing global public health concern, particularly among populations of African ancestry...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Liu CT, Garnaas MK, Tin A, Kottgen A, Franceschini N, Peralta CA, de Boer IH, Lu X, Atkinson E, Ding J, Nalls M, Shriner D, Coresh J, Kutlar A, Bibbins-Domingo K, Siscovick D, Akylbekova E, Wyatt S, Astor B, Mychaleckjy J, Man Li M, Reilly MP, Townsend RR, Adeyemo A, Zonderman AB, de Andrade M, Turner ST, Mosley TH, Harris TB, The CKDGen Consortium, Rotimi CN, Liu Y, Kardia SLR, Evans MK, Shlipak MG, Kramer H, Flessner MF, Dreisbach AW, Goessling W, Cupples LA, Kao WL, Fox CS. Genetic Association for Renal Traits among Participants of African Ancestry Reveals New Loci for Renal Function. PLoS Genet. 2011;7(9): e1002264. doi:10.1371/journal.pgen.1002264.

Haploinsufficiency of KDM6A is associated with severe psychomotor retardation, global growth restriction, seizures and cleft palate

Authors:
Lindgren AM, Hoyos T, Talkowski ME, Hanscom C, Blumenthal I, Chiang C, Ernst C, Pereira S, Ordulu Z, Clericuzio C, Drautz JM, Rosenfeld JA, Shaffer LG, Velsher L, Pynn T, Vermeesch J, Harris DJ, Gusella JF, Liao EC, Morton CC
Citation:
Hum Genet. 2013 Jan 25. [Epub ahead of print]
Epub:
Not Epub
Abstract:
We describe a female subject (DGAP100) with a 46,X,t(X;5)(p11.3;q35.3)inv(5)(q35.3q35.1)dn, severe psychomotor retardation with...
Organism or Cell Type:
zebrafish
Citation Extract:
Lindgren AM, Hoyos T, Talkowski ME, Hanscom C, Blumenthal I, Chiang C, Ernst C, Pereira S, Ordulu Z, Clericuzio C, Drautz JM, Rosenfeld JA, Shaffer LG, Velsher L, Pynn T, Vermeesch J, Harris DJ, Gusella JF, Liao EC, Morton CC. Haploinsufficiency of KDM6A is associated with severe psychomotor retardation, global growth restriction, seizures and cleft palate. Hum Genet. 2013 Jan 25. [Epub ahead of print].

Human islet cell MORF/cMORF pretargeting in a xenogeneic murine transplant model

Authors:
Liu G, Dou S, Cheng D, Leif J, Rusckowski M, Streeter PR, Schultz LD, Hnatowich D, Greiner D
Citation:
Mol Pharm. 2011 Jun 6;8(3):767-73. doi: 10.1021/mp100382m. Epub 2011 Apr 21
Epub:
Not Epub
Abstract:
Non-invasive measurement of human islet cell mass in pancreas or following islet transplantation by nuclear imaging has yet to...
Delivery Method:
Injection
Organism or Cell Type:
mice, cell cultures
Citation Extract:
Liu G, Dou S, Cheng D, Leif J, Rusckowski M, Streeter PR, Schultz LD, Hnatowich D, Greiner D. Human islet cell MORF/cMORF pretargeting in a xenogeneic murine transplant model. Mol Pharm. 2011 Jun 6;8(3):767-73. doi: 10.1021/mp100382m. Epub 2011 Apr 21.

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