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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12095 scientific papers returned from the database with the search filters currently being used below.

Temtamy Preaxial Brachydactyly Syndrome Is Caused by Loss-of-Function Mutations in Chondroitin Synthase 1, a Potential Target of BMP Signaling

Authors:
Li Y, Laue K, Temtamy S, Aglan M, Kotan LD, Yigit G, Canan H, Pawlik B, Nürnberg G, Wakeling EL, Quarrell OW, Baessmann I, Lanktree MB, Yilmaz M, Hegele RA, Amr K, May KW, Nürnberg P, Topaloglu AK, Hammerschmidt M, Wollnik B
Citation:
Am J Hum Genet. 2010 Dec 1. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Altered Bone Morphogenetic Protein (BMP) signaling leads to multiple developmental defects, including brachydactyly and...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Li Y, Laue K, Temtamy S, Aglan M, Kotan LD, Yigit G, Canan H, Pawlik B, Nürnberg G, Wakeling EL, Quarrell OW, Baessmann I, Lanktree MB, Yilmaz M, Hegele RA, Amr K, May KW, Nürnberg P, Topaloglu AK, Hammerschmidt M, Wollnik B. Temtamy Preaxial Brachydactyly Syndrome Is Caused by Loss-of-Function Mutations in Chondroitin Synthase 1, a Potential Target of BMP Signaling. Am J Hum Genet. 2010 Dec 1. [Epub ahead of print].

The abcc6a Gene Expression Is Required for Normal Zebrafish Development

Authors:
Li Q, Sadowski S, Frank M, Chai C, Váradi A, Ho SY, Lou H, Dean M, Thisse C, Thisse B, Uitto J
Citation:
J Invest Dermatol. 2010 Jul 1. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Pseudoxanthoma elasticum (PXE) is caused by mutations in the ABCC6 gene, which encodes a putative efflux transporter, ABCC6....
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Li Q, Sadowski S, Frank M, Chai C, Váradi A, Ho SY, Lou H, Dean M, Thisse C, Thisse B, Uitto J. The abcc6a Gene Expression Is Required for Normal Zebrafish Development. J Invest Dermatol. 2010 Jul 1. [Epub ahead of print].

The essential role of endogenous ghrelin in growth hormone expression during zebrafish adenohypophysis development

Authors:
Li X, He J, Hu W, Yin Z
Citation:
Endocrinology. 2009 Mar 5. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Ghrelin, a multi-functional hormone, including potent growth hormone stimulation activity, has been suggested to be important...
Organism or Cell Type:
zebrafish
Citation Extract:
Li X, He J, Hu W, Yin Z. The essential role of endogenous ghrelin in growth hormone expression during zebrafish adenohypophysis development. Endocrinology. 2009 Mar 5. [Epub ahead of print].

The stat3/socs3a Pathway Is a Key Regulator of Hair Cell Regeneration in Zebrafish stat3/socs3a Pathway: Regulator of Hair Cell Regeneration

Authors:
Liang J, Wang D, Renaud G, Wolfsberg TG, Wilson AF, Burgess SM
Citation:
J Neurosci. 2012;32(31):10662-73. doi:10.1523/​JNEUROSCI.5785-10.2012
Epub:
Not Epub
Abstract:
All nonmammalian vertebrates studied can regenerate inner ear mechanosensory receptors (i.e., hair cells) (Corwin and Cotanche...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Liang J, Wang D, Renaud G, Wolfsberg TG, Wilson AF, Burgess SM. The stat3/socs3a Pathway Is a Key Regulator of Hair Cell Regeneration in Zebrafish stat3/socs3a Pathway: Regulator of Hair Cell Regeneration. J Neurosci. 2012;32(31):10662-73. doi:10.1523/​JNEUROSCI.5785-10.2012 .

The transcription factor ZBP-89 controls generation of the hematopoietic lineage in zebrafish and mouse embryonic stem cells

Authors:
Li X, Xiong JW, Shelley CS, Park H, Arnaout MA
Citation:
Development. 2006 Sep;133(18):3641-50. Epub 2006 Aug 16.
Epub:
Not Epub
Abstract:
Hematopoietic development is closely linked to that of blood vessels and the two processes are regulated in large part by...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Li X, Xiong JW, Shelley CS, Park H, Arnaout MA. The transcription factor ZBP-89 controls generation of the hematopoietic lineage in zebrafish and mouse embryonic stem cells. Development. 2006 Sep;133(18):3641-50. Epub 2006 Aug 16..

Transmembrane protein 198 promotes LRP6 phosphorylation and Wnt signaling activation

Authors:
Liang J, Fu Y, Cruciat CM, Jia S, Wang Y, Tong Z, Tao Q, Ingelfinger D, Boutros M, Meng A, Niehrs C, Wu W
Citation:
Mol Cell Biol. 2011 Jul;31(13):2577-90. Epub 2011 May 2
Epub:
Not Epub
Abstract:
Wnt/β-catenin signaling is fundamental in embryogenesis and tissue homeostasis in metazoans. Upon Wnt stimulation, cognate...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Liang J, Fu Y, Cruciat CM, Jia S, Wang Y, Tong Z, Tao Q, Ingelfinger D, Boutros M, Meng A, Niehrs C, Wu W. Transmembrane protein 198 promotes LRP6 phosphorylation and Wnt signaling activation. Mol Cell Biol. 2011 Jul;31(13):2577-90. Epub 2011 May 2.

Xenopus as a Model System for the Study of GOLPH2/GP73 Function: Xenopus golph2 Is Required for Pronephros Development

Authors:
Li L, Wen L, Gong Y, Mei G, Liu J, Chen Y, Peng T
Citation:
PLoS ONE. 2012;7(6):e38939. doi:10.1371/journal.pone.0038939
Epub:
Not Epub
Abstract:
GOLPH2 is a highly conserved protein. It is upregulated in a number of tumors and is being considered as an emerging biomarker...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Li L, Wen L, Gong Y, Mei G, Liu J, Chen Y, Peng T. Xenopus as a Model System for the Study of GOLPH2/GP73 Function: Xenopus golph2 Is Required for Pronephros Development. PLoS ONE. 2012;7(6):e38939. doi:10.1371/journal.pone.0038939.

Zebrafish as a model system to study heritable skin diseases

Authors:
Li Q, Uitto J
Citation:
Methods Mol Biol. 2013;961:411-24. doi: 10.1007/978-1-62703-227-8_28
Epub:
Not Epub
Abstract:
Heritable skin diseases represent a broad spectrum of clinical manifestations due to mutations in ∼500 different genes. A...
Organism or Cell Type:
zebrafish
Citation Extract:
Li Q, Uitto J. Zebrafish as a model system to study heritable skin diseases. Methods Mol Biol. 2013;961:411-24. doi: 10.1007/978-1-62703-227-8_28.

Zebrafish peptidoglycan recognition proteins are bactericidal amidases essential for defense against bacterial infections

Authors:
Li X, Wang S, Qi J, Echtenkamp SF, Chatterjee R, Wang M, Boons GJ, Dziarski R, Gupta D
Citation:
Immunity. 2007 Sep;27(3):518-29
Epub:
Not Epub
Abstract:
Peptidoglycan recognition proteins (PGRPs) are structurally conserved through evolution, but their functions in innate immunity...
Organism or Cell Type:
zebrafish
Citation Extract:
Li X, Wang S, Qi J, Echtenkamp SF, Chatterjee R, Wang M, Boons GJ, Dziarski R, Gupta D. Zebrafish peptidoglycan recognition proteins are bactericidal amidases essential for defense against bacterial infections. Immunity. 2007 Sep;27(3):518-29.

Morpholino phenocopies of the swirl, snailhouse, somitabun, minifin, silberblick, and pipetail mutations

Authors:
Lele Z, Bakkers J, Hammerschmidt M.
Citation:
Genesis. 2001 Jul;30(3):190-4
Epub:
Not Epub
Abstract:
No abstract available.
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lele Z, Bakkers J, Hammerschmidt M.. Morpholino phenocopies of the swirl, snailhouse, somitabun, minifin, silberblick, and pipetail mutations. Genesis. 2001 Jul;30(3):190-4.

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