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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12387 scientific papers returned from the database with the search filters currently being used below.

Loss of gata1 but not gata2 converts erythropoiesis to myelopoiesis in zebrafish embryos.

Authors:
Galloway JL, Wingert RA, Thisse C, Thisse B, Zon LI
Citation:
Dev Cell. 2005 Jan;8(1):109-16
Epub:
Not Epub
Abstract:
The differentiation of hematopoietic progenitors into erythroid or myeloid cell lineages is thought to depend upon relative...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Galloway JL, Wingert RA, Thisse C, Thisse B, Zon LI. Loss of gata1 but not gata2 converts erythropoiesis to myelopoiesis in zebrafish embryos.. Dev Cell. 2005 Jan;8(1):109-16.

Low MAD2 expression levels associate with reduced progression-free survival in patients with high-grade serous epithelial ovarian cancer

Authors:
Furlong F, Fitzpatrick P, O'Toole S, Phelan S, McGrogan B, Maguire A, O'Grady A, Gallagher M, Prencipe M, McGoldrick A, McGettigan P, Brennan D, Sheils O, Martin C, W Kay E, O'Leary J, McCann A
Citation:
J Pathol. 2012 Apr;226(5):746-55. doi: 10.1002/path.3035. Epub 2012 Jan 17
Epub:
Not Epub
Abstract:
Epithelial ovarian cancer (EOC) has an innate susceptibility to become chemoresistant. Up to 30% of patients do not respond to...
Delivery Method:
Hiperfect (Qiagen)
Organism or Cell Type:
cell culture: A2780 ovarian cancer line
Citation Extract:
Furlong F, Fitzpatrick P, O'Toole S, Phelan S, McGrogan B, Maguire A, O'Grady A, Gallagher M, Prencipe M, McGoldrick A, McGettigan P, Brennan D, Sheils O, Martin C, W Kay E, O'Leary J, McCann A. Low MAD2 expression levels associate with reduced progression-free survival in patients with high-grade serous epithelial ovarian cancer. J Pathol. 2012 Apr;226(5):746-55. doi: 10.1002/path.3035. Epub 2012 Jan 17.

Methods for Evaluation of Antisense Mechanisms of Action

Authors:
Ghosh C, Stein D, Weller D, Iversen P
Citation:
In Antisense Technology Part A, General Methods, Methods of Delivery, and RNA Studies. Methods in Enzymology vol.313. 1999. (Ed. Ian Phillips) Academic Press. pp. 135-142
Epub:
Not Epub
Abstract:
No abstract available.
Citation Extract:
Ghosh C, Stein D, Weller D, Iversen P. Methods for Evaluation of Antisense Mechanisms of Action. In Antisense Technology Part A, General Methods, Methods of Delivery, and RNA Studies. Methods in Enzymology vol.313. 1999. (Ed. Ian Phillips) Academic Press. pp. 135-142.

MicroRNAs Regulate Brain Morphogenesis in Zebrafish

Authors:
Giraldez AJ, Cinalli RM, Glasner ME, Enright AJ, Thomson MJ, Baskerville S, Hammond SM, Bartel DP, Schier AF
Citation:
Science. 2005 May 6;308(5723):833-8.
Epub:
Not Epub
Abstract:
MicroRNAs (miRNAs) are small RNAs that regulate gene expression post-transcriptionally. To block all miRNA formation in...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Giraldez AJ, Cinalli RM, Glasner ME, Enright AJ, Thomson MJ, Baskerville S, Hammond SM, Bartel DP, Schier AF. MicroRNAs Regulate Brain Morphogenesis in Zebrafish. Science. 2005 May 6;308(5723):833-8..

Mir-144 selectively regulates embryonic alpha-hemoglobin synthesis during primitive erythropoiesis

Authors:
Fu YF, Du TT, Dong M, Zhu KY, Jing CB, Zhang Y, Wang L, Fan HB, Chen Y, Jin Y, Yue GP, Chen SJ, Chen Z, Huang QH, Jing Q, Deng M, Liu TX
Citation:
Blood. 2009 Feb 5;113(6):1340-9. Epub 2008 Oct 21
Epub:
Not Epub
Abstract:
Precise transcriptional control of developmental stage-specific expression and switching of alpha- and beta-globin genes is...
Organism or Cell Type:
zebrafish
Citation Extract:
Fu YF, Du TT, Dong M, Zhu KY, Jing CB, Zhang Y, Wang L, Fan HB, Chen Y, Jin Y, Yue GP, Chen SJ, Chen Z, Huang QH, Jing Q, Deng M, Liu TX. Mir-144 selectively regulates embryonic alpha-hemoglobin synthesis during primitive erythropoiesis. Blood. 2009 Feb 5;113(6):1340-9. Epub 2008 Oct 21.

Molecular cloning and functional analysis of scavenger receptor zebrafish CL-P1

Authors:
Fukuda M, Ohtani K, Jang SJ, Yoshizaki T, Mori KI, Motomura W, Yoshida I, Suzuki Y, Kohgo Y, Wakamiya N
Citation:
Biochim Biophys Acta. 2011 Oct 4. [Epub ahead of print]
Epub:
Not Epub
Abstract:
BACKGROUND: Scavenger receptors are generally expressed in macrophages and vascular endothelial cells and some scavenger...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Fukuda M, Ohtani K, Jang SJ, Yoshizaki T, Mori KI, Motomura W, Yoshida I, Suzuki Y, Kohgo Y, Wakamiya N. Molecular cloning and functional analysis of scavenger receptor zebrafish CL-P1. Biochim Biophys Acta. 2011 Oct 4. [Epub ahead of print].

Molecular dissection of the migrating posterior lateral line primordium during early development in zebrafish

Authors:
Gallardo VE, Liang J, Behra M, Elkahloun A, Villablanca EJ, Russo V, Allende ML, Burgess SM
Citation:
BMC Dev Biol. 2010 Dec 13;10:120
Epub:
Not Epub
Abstract:
BACKGROUND: Development of the posterior lateral line (PLL) system in zebrafish involves cell migration, proliferation and...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Gallardo VE, Liang J, Behra M, Elkahloun A, Villablanca EJ, Russo V, Allende ML, Burgess SM. Molecular dissection of the migrating posterior lateral line primordium during early development in zebrafish. BMC Dev Biol. 2010 Dec 13;10:120.

Morpholino artifacts provide pitfalls and reveal a novel role for pro-apoptotic genes in hindbrain boundary development

Authors:
Gerety SS, Wilkinson DG
Citation:
Dev Biol. 2011;350(2):279-289. doi:10.1016/j.ydbio.2010.11.030
Epub:
Not Epub
Abstract:
Morpholino antisense oligonucleotides (MOs) are widely used as a tool to achieve loss of gene function, but many have off-...
Organism or Cell Type:
zebrafish
Citation Extract:
Gerety SS, Wilkinson DG. Morpholino artifacts provide pitfalls and reveal a novel role for pro-apoptotic genes in hindbrain boundary development. Dev Biol. 2011;350(2):279-289. doi:10.1016/j.ydbio.2010.11.030.

Morpholino oligomers targeting the PB1 and NP genes enhance the survival of mice infected with highly pathogenic influenza A H7N7 virus

Authors:
Gabriel G, Nordmann A, Stein DA, Iversen PL, Klenk HD
Citation:
J Gen Virol. 2008 Apr;89(Pt 4):939-48
Epub:
Not Epub
Abstract:
Peptide-conjugated phosphorodiamidate morpholino oligomers (PPMO) are single-stranded nucleic acid-analogue antisense agents...
Delivery Method:
peptide-coupled
Organism or Cell Type:
mice and cell cultures: MDCK
Citation Extract:
Gabriel G, Nordmann A, Stein DA, Iversen PL, Klenk HD. Morpholino oligomers targeting the PB1 and NP genes enhance the survival of mice infected with highly pathogenic influenza A H7N7 virus. J Gen Virol. 2008 Apr;89(Pt 4):939-48.

Mustn1 is essential for craniofacial chondrogenesis during Xenopus development

Authors:
Gersch RP, Kirmizitas A, Sobkow L, Sorrentino G, Thomsen GH, Hadjiargyrou M
Citation:
Gene Expr Patterns. 2012 Jan 18. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Mustn1 is a vertebrate-specific protein that, in vitro, was showed to be essential for prechondrocyte function and thus it has...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Gersch RP, Kirmizitas A, Sobkow L, Sorrentino G, Thomsen GH, Hadjiargyrou M. Mustn1 is essential for craniofacial chondrogenesis during Xenopus development. Gene Expr Patterns. 2012 Jan 18. [Epub ahead of print].

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