You are here

Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12550 scientific papers returned from the database with the search filters currently being used below.

In vivo imaging reveals exosome-mediated intercellular communication in lens development

Authors:
Ma J, Sun Q, Chen Y, Li J, Ouyang S, Ke S, Li J, Liang H, Chen S, Luo L
Citation:
Commun Biol 8, 1774 (2025). https://doi.org/10.1038/s42003-025-09159-5
Epub:
Not Epub
Abstract:
Lens transparency relies on proper intercellular communication. Exosomes are crucial mediators of intercellular communication...
Link:
https://www.nature.com/articles/s42003-025-09159-5
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ma J, Sun Q, Chen Y, Li J, Ouyang S, Ke S, Li J, Liang H, Chen S, Luo L. In vivo imaging reveals exosome-mediated intercellular communication in lens development. Commun Biol 8, 1774 (2025). https://doi.org/10.1038/s42003-025-09159-5.

Suppression of brain aromatase decreases the expression of dopaminergic neuron in early development of zebrafish

Authors:
Fatimah R, Ulhaq ZS, Rafiuddin MA, Kishida M
Citation:
Fish Physiol Biochem. 2025 Dec 13;51(6):204. doi: 10.1007/s10695-025-01620-w. PMID: 41389094
Epub:
Not Epub
Abstract:
Cytochrome P450 aromatase, the product of the CYP19A1 gene, is a key enzyme in estrogen biosynthesis. Most teleost fish have...
Link:
https://link.springer.com/article/10.1007/s10695-025-01620-w
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Fatimah R, Ulhaq ZS, Rafiuddin MA, Kishida M. Suppression of brain aromatase decreases the expression of dopaminergic neuron in early development of zebrafish. Fish Physiol Biochem. 2025 Dec 13;51(6):204. doi: 10.1007/s10695-025-01620-w. PMID: 41389094.

Pathogenic Mechanism of the KCNQ4 Gene Variant in Hearing Loss and Functional Validation in a Zebrafish Model

Authors:
Jia H, Liu X, Chen H, Wang Y, Guan MX, Guo Y
Citation:
FASEB J. 2025 Dec 15;39(23):e71274. doi: 10.1096/fj.202500557R. PMID: 41368761
Epub:
Not Epub
Abstract:
The KCNQ4 gene is closely associated with autosomal dominant nonsyndromic hearing loss (DFNA2) and encodes a potassium channel...
Link:
https://faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202500557R
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Jia H, Liu X, Chen H, Wang Y, Guan MX, Guo Y. Pathogenic Mechanism of the KCNQ4 Gene Variant in Hearing Loss and Functional Validation in a Zebrafish Model. FASEB J. 2025 Dec 15;39(23):e71274. doi: 10.1096/fj.202500557R. PMID: 41368761.

Ace2 safeguards embryonic hematopoietic stem and progenitor cell production by restraining Nlrp3-mediated pyroptosis

Authors:
Xia J, Shen L, Liu Y, Wang L, Liu F
Citation:
Proc Natl Acad Sci U S A. 2025 Dec 9;122(49):e2515641122. doi: 10.1073/pnas.2515641122. Epub 2025 Dec 5. PMID: 41348733
Epub:
Not Epub
Abstract:
During vertebrate embryogenesis, hematopoietic stem and progenitor cells (HSPCs) originate from hemogenic endothelium (HE) in...
Link:
https://www.pnas.org/doi/10.1073/pnas.2515641122
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Xia J, Shen L, Liu Y, Wang L, Liu F. Ace2 safeguards embryonic hematopoietic stem and progenitor cell production by restraining Nlrp3-mediated pyroptosis. Proc Natl Acad Sci U S A. 2025 Dec 9;122(49):e2515641122. doi: 10.1073/pnas.2515641122. Epub 2025 Dec 5. PMID: 41348733.

Vascular Lamb1 guides the migration of retinal microglial precursors via Itga6-Rac1 signaling

Authors:
Zhan D, Xu L, Mu W, Jin B, Feng Z, Liu S, Wu C, Luo L, Li L
Citation:
Cell Rep. 2025 Nov 25;44(11):116544. doi: 10.1016/j.celrep.2025.116544. Epub 2025 Nov 8. PMID: 41206867
Epub:
Not Epub
Abstract:
Retinal microglia originate during embryonic hematopoiesis and play an essential role in visual function. However, the...
Link:
https://www.cell.com/cell-reports/fulltext/S2211-1247(25)01315-4
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhan D, Xu L, Mu W, Jin B, Feng Z, Liu S, Wu C, Luo L, Li L. Vascular Lamb1 guides the migration of retinal microglial precursors via Itga6-Rac1 signaling. Cell Rep. 2025 Nov 25;44(11):116544. doi: 10.1016/j.celrep.2025.116544. Epub 2025 Nov 8. PMID: 41206867.

Multiple retinoic acid pathway factors function together during development of a mollusk

Authors:
Dao TK & Lambert JD
Citation:
bioRxiv 2025.12.01.691671; doi: https://doi.org/10.64898/2025.12.01.691671
Epub:
Not Epub
Abstract:
In developing chordate embryos, the retinoic acid (RA) pathway is involved in many key developmental patterning systems....
Link:
https://www.biorxiv.org/content/10.64898/2025.12.01.691671v1.full
Delivery Method:
microinjection
Organism or Cell Type:
Tritia obsoleta (previously Ilyanassa obsoleta) gastropod
Citation Extract:
Dao TK & Lambert JD. Multiple retinoic acid pathway factors function together during development of a mollusk. bioRxiv 2025.12.01.691671; doi: https://doi.org/10.64898/2025.12.01.691671.

The role of AP2M1 in oncofetal characteristics: integrative in silico, in vitro, and in vivo analyses using zebrafish models

Authors:
Ahn S, Baek SE, Yu Y, Kim ES, Myung K, Kim YH, Oh CK
Citation:
Eur J Med Res. 2025 Dec 1. doi: 10.1186/s40001-025-03583-3. Epub ahead of print. PMID: 41327404
Epub:
Not Epub
Abstract:
Hepatocellular carcinoma (HCC) requires novel therapeutic targets, and oncofetal genes offer a promising avenue. Although the...
Link:
https://link.springer.com/article/10.1186/s40001-025-03583-3
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ahn S, Baek SE, Yu Y, Kim ES, Myung K, Kim YH, Oh CK. The role of AP2M1 in oncofetal characteristics: integrative in silico, in vitro, and in vivo analyses using zebrafish models. Eur J Med Res. 2025 Dec 1. doi: 10.1186/s40001-025-03583-3. Epub ahead of print. PMID: 41327404.

A 16-amino acid peptide delays the progression of motor neuron degeneration and pathogenic symptoms in ALS models

Authors:
Lin CY, Lee BC, Zhang PH, Lu SC, Chang WZ, Wang CC, Tsai HJ
Citation:
Neurotherapeutics. 2025 Nov 25:e00806. doi: 10.1016/j.neurot.2025.e00806. Epub ahead of print. PMID: 41298223
Epub:
Not Epub
Abstract:
Amyotrophic lateral sclerosis (ALS) is a progressive motor neurons (MNs) degenerative disease. Despite advancements in...
Link:
https://www.sciencedirect.com/science/article/pii/S1878747925002843
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lin CY, Lee BC, Zhang PH, Lu SC, Chang WZ, Wang CC, Tsai HJ. A 16-amino acid peptide delays the progression of motor neuron degeneration and pathogenic symptoms in ALS models. Neurotherapeutics. 2025 Nov 25:e00806. doi: 10.1016/j.neurot.2025.e00806. Epub ahead of print. PMID: 41298223.

PCM1 coordinates centrosome asymmetry with polarized endosome dynamics to regulate daughter cell fate

Authors:
Zhao X, Mouilleau V, Wang Y, Solak AC, Garcia JQ, Chen X, Shi X, Wilkinson CJ, Royer LA, Dong Z, Guo S
Citation:
Nat Commun. 2025 Nov 28;16(1):10728. doi: 10.1038/s41467-025-65756-2. PMID: 41315244; PMCID: PMC12663461
Epub:
Not Epub
Abstract:
Vertebrate radial glia progenitors (RGPs) balance self-renewal and differentiation through asymmetric cell division (ACD),...
Link:
https://www.nature.com/articles/s41467-025-65756-2
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhao X, Mouilleau V, Wang Y, Solak AC, Garcia JQ, Chen X, Shi X, Wilkinson CJ, Royer LA, Dong Z, Guo S. PCM1 coordinates centrosome asymmetry with polarized endosome dynamics to regulate daughter cell fate. Nat Commun. 2025 Nov 28;16(1):10728. doi: 10.1038/s41467-025-65756-2. PMID: 41315244; PMCID: PMC12663461.

DIS3 licenses B cells for plasma cell differentiation in humans

Authors:
Miglierina E, Bouder J, Ordanoska D, Pineau M, Léonard S, Schavgoulidze A, Quéré G, Le Goff M, Bouchet M, Genebrier SA, Trinca SBS, Deleurme L, Monvoisin C, Derrier L, Dumontet C, Delpy L, Moreaux J, Corre J, Cogné M, Laffleur B
Citation:
Cell Mol Immunol. 2025 Nov 25. doi: 10.1038/s41423-025-01369-5. Epub ahead of print. PMID: 41286079
Epub:
Not Epub
Abstract:
DIS3 is the main catalytic subunit of the nuclear RNA exosome, a complex playing a crucial role in RNA processing and the...
Link:
https://www.nature.com/articles/s41423-025-01369-5
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
Primary B cells from C57BL/6J crossed with 129/SvJ mice and healthy human donors; SSK41 human B cell line
Citation Extract:
Miglierina E, Bouder J, Ordanoska D, Pineau M, Léonard S, Schavgoulidze A, Quéré G, Le Goff M, Bouchet M, Genebrier SA, Trinca SBS, Deleurme L, Monvoisin C, Derrier L, Dumontet C, Delpy L, Moreaux J, Corre J, Cogné M, Laffleur B. DIS3 licenses B cells for plasma cell differentiation in humans. Cell Mol Immunol. 2025 Nov 25. doi: 10.1038/s41423-025-01369-5. Epub ahead of print. PMID: 41286079.

Pages