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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12378 scientific papers returned from the database with the search filters currently being used below.

An evaluation of oligonucleotide-based therapeutic strategies for polyQ diseases

Authors:
Fiszer A, Olejniczak M, Switonski PM, Wroblewska JP, Wisniewska-Kruk JW, Mykowska A, Krzyzosiak WJ
Citation:
BMC Mol Biol. 2012;13:6 doi:10.1186/1471-2199-13-6
Epub:
Not Epub
Abstract:
RNA interference (RNAi) and antisense strategies provide experimental therapeutic agents for numerous diseases, including...
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: primary human fibroblasts, Huntington disease
Citation Extract:
Fiszer A, Olejniczak M, Switonski PM, Wroblewska JP, Wisniewska-Kruk JW, Mykowska A, Krzyzosiak WJ. An evaluation of oligonucleotide-based therapeutic strategies for polyQ diseases. BMC Mol Biol. 2012;13:6 doi:10.1186/1471-2199-13-6.

Analysis of gastrointestinal physiology using a novel intestinal transit assay in zebrafish

Authors:
Field HA, Kelley KA, Martell L, Goldstein AM, Serluca FC
Citation:
Neurogastroenterol Motil. 2009 Mar;21(3):304-12. Epub 2008 Dec 31
Epub:
Not Epub
Abstract:
Gastrointestinal function depends upon coordinated contractions to mix and propel food through the gut. Deregulation of these...
Organism or Cell Type:
zebrafish
Citation Extract:
Field HA, Kelley KA, Martell L, Goldstein AM, Serluca FC. Analysis of gastrointestinal physiology using a novel intestinal transit assay in zebrafish. Neurogastroenterol Motil. 2009 Mar;21(3):304-12. Epub 2008 Dec 31.

Analysis of transcriptional codes for zebrafish dopaminergic neurons reveals essential functions of Arx and Isl1 in prethalamic dopaminergic neuron development

Authors:
Filippi A, Jainok C, Driever W
Citation:
Dev Biol. 2012 Jun 20. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Distinct groups of dopaminergic neurons develop at defined anatomical sites in the brain to modulate function of a large...
Organism or Cell Type:
zebrafish
Citation Extract:
Filippi A, Jainok C, Driever W. Analysis of transcriptional codes for zebrafish dopaminergic neurons reveals essential functions of Arx and Isl1 in prethalamic dopaminergic neuron development. Dev Biol. 2012 Jun 20. [Epub ahead of print].

Anti-infectives: Post-exposure antisense protection against lethal filoviruses?

Authors:
Flemming A
Citation:
Nat Rev Drug Discov. 2010 Oct;9(10):764-5
Epub:
Not Epub
Abstract:
No abstract available.
Delivery Method:
PMO+
Citation Extract:
Flemming A. Anti-infectives: Post-exposure antisense protection against lethal filoviruses?. Nat Rev Drug Discov. 2010 Oct;9(10):764-5.

Antisense suppression of donor splice site mutations in the dystrophin gene transcript

Authors:
Fletcher S, Meloni PL, Johnsen RD, Wong BL, Muntoni F, Wilton SD
Citation:
Mol Genet Genomic Med. 2013 Sep;1(3):162-73. doi: 10.1002/mgg3.19. Epub 2013 Jun 13. PMID: 24498612; PMCID: PMC3865583
Epub:
Not Epub
Abstract:
We describe two donor splice site mutations, affecting dystrophin exons 16 and 45 that led to Duchenne muscular dystrophy (DMD...
Link:
https://pmc.ncbi.nlm.nih.gov/articles/PMC3865583/
Delivery Method:
peptide-coupled
Organism or Cell Type:
cell culture: human primary fibroblasts and myogenic cells (subsequently differentiated)
Citation Extract:
Fletcher S, Meloni PL, Johnsen RD, Wong BL, Muntoni F, Wilton SD. Antisense suppression of donor splice site mutations in the dystrophin gene transcript. Mol Genet Genomic Med. 2013 Sep;1(3):162-73. doi: 10.1002/mgg3.19. Epub 2013 Jun 13. PMID: 24498612; PMCID: PMC3865583.

Apoptotic and proliferative defects characterize ocular development in a microphthalmic BMP model

Authors:
French CR, Stach TR, March LD, Lehmann OJ, Waskiewicz AJ
Citation:
Invest Ophthalmol Vis Sci. 2013 Jun 4. doi:pii: iovs.13-11674v1. 10.1167/iovs.13-11674. [Epub ahead of print]
Epub:
Not Epub
Abstract:
PURPOSE: Vision is critically dependent on ocular size, which is regulated by environmental and genetic factors. Mutation of...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
French CR, Stach TR, March LD, Lehmann OJ, Waskiewicz AJ. Apoptotic and proliferative defects characterize ocular development in a microphthalmic BMP model. Invest Ophthalmol Vis Sci. 2013 Jun 4. doi:pii: iovs.13-11674v1. 10.1167/iovs.13-11674. [Epub ahead of print].

Ascl1b and Neurod1, instead of Neurog3, control pancreatic endocrine cell fate in zebrafish

Authors:
Flasse LC, Pirson JL, Stern DG, Von Berg V, Manfroid I, Peers B, Voz ML
Citation:
BMC Biol. 2013 Jul 8;11(1):78. [Epub ahead of print]
Epub:
Not Epub
Abstract:
BACKGROUND: NEUROG3 is a key regulator of pancreatic endocrine cell differentiation in mouse, essential for the generation of...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Flasse LC, Pirson JL, Stern DG, Von Berg V, Manfroid I, Peers B, Voz ML. Ascl1b and Neurod1, instead of Neurog3, control pancreatic endocrine cell fate in zebrafish. BMC Biol. 2013 Jul 8;11(1):78. [Epub ahead of print].

Base Excision Repair in Early Zebrafish Development: Evidence for DNA Polymerase Switching and Standby AP endonuclease Activity

Authors:
Fortier S, Yang X, Wang Y, Bennett RA, Strauss PR
Citation:
Biochemistry. 2009 Apr 17. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The base excision repair (BER) pathway recognizes and repairs most non-bulky lesions, uracil and abasic (AP) sites in DNA....
Organism or Cell Type:
zebrafish
Citation Extract:
Fortier S, Yang X, Wang Y, Bennett RA, Strauss PR. Base Excision Repair in Early Zebrafish Development: Evidence for DNA Polymerase Switching and Standby AP endonuclease Activity. Biochemistry. 2009 Apr 17. [Epub ahead of print].

Combinatorial activity of Flamingo proteins directs convergence and extension within the early zebrafish embryo via the planar cell polarity pathway

Authors:
Formstone CJ, Mason I
Citation:
Dev Biol. 2005 Jun 15;282(2):320-35.
Epub:
Not Epub
Abstract:
The seven-transmembrane protocadherin, Flamingo, functions in a number of processes during Drosophila development, including...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Formstone CJ, Mason I. Combinatorial activity of Flamingo proteins directs convergence and extension within the early zebrafish embryo via the planar cell polarity pathway. Dev Biol. 2005 Jun 15;282(2):320-35..

Complex I deficiency and dopaminergic neuronal cell loss in parkin-deficient zebrafish (Danio rerio)

Authors:
Flinn L, Mortiboys H, Volkmann K, Köster RW, Ingham PW, Bandmann O
Citation:
Brain. 2009 May 12. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Currently, only symptomatic therapy is available for Parkinson's disease. The zebrafish is a vertebrate animal model...
Organism or Cell Type:
zebrafish
Citation Extract:
Flinn L, Mortiboys H, Volkmann K, Köster RW, Ingham PW, Bandmann O. Complex I deficiency and dopaminergic neuronal cell loss in parkin-deficient zebrafish (Danio rerio). Brain. 2009 May 12. [Epub ahead of print].

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