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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12378 scientific papers returned from the database with the search filters currently being used below.

The planar polarity gene strabismus regulates convergent extension movements in Xenopus

Authors:
Darken RS, Scola AM, Rakeman AS, Das G, Mlodzik M, Wilson PA
Citation:
EMBO J. 2002 Mar; 21(5):976-985
Epub:
Not Epub
Abstract:
The signaling mechanisms that specify, guide and coordinate cell behavior during embryonic morphogenesis are poorly understood...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Darken RS, Scola AM, Rakeman AS, Das G, Mlodzik M, Wilson PA. The planar polarity gene strabismus regulates convergent extension movements in Xenopus. EMBO J. 2002 Mar; 21(5):976-985.

Topoisomerase II-Mediated DNA Damage Is Differently Repaired during the Cell Cycle by Non-Homologous End Joining and Homologous Recombination

Authors:
de Campos-Nebel M, Larripa I, González-Cid M
Citation:
PLoS One. 2010 Sep 2;5(9). pii: e12541
Epub:
Not Epub
Abstract:
Topoisomerase II (Top2) is a nuclear enzyme involved in several metabolic processes of DNA. Chemotherapy agents that poison...
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: human fibroblasts
Citation Extract:
de Campos-Nebel M, Larripa I, González-Cid M. Topoisomerase II-Mediated DNA Damage Is Differently Repaired during the Cell Cycle by Non-Homologous End Joining and Homologous Recombination. PLoS One. 2010 Sep 2;5(9). pii: e12541.

Tryptophan scanning mutagenesis of the first transmembrane domain of the innexin Shaking-B(Lethal)

Authors:
Depriest A, Phelan P, Martha Skerrett I
Citation:
Biophys J. 2011 Nov 16;101(10):2408-16. Epub 2011 Nov 15
Epub:
Not Epub
Abstract:
The channel proteins of gap junctions are encoded by two distinct gene families, connexins, which are exclusive to chordates,...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Depriest A, Phelan P, Martha Skerrett I. Tryptophan scanning mutagenesis of the first transmembrane domain of the innexin Shaking-B(Lethal). Biophys J. 2011 Nov 16;101(10):2408-16. Epub 2011 Nov 15.

TTC21B contributes both causal and modifying alleles across the ciliopathy spectrum

Authors:
Davis EE, Zhang Q, Liu Q, Diplas BH, Davey LM, Hartley J, Stoetzel C, Szymanska K, Ramaswami G, Logan CV, Muzny DM, Young AC, Wheeler DA, Cruz P, Morgan M, Lewis LR, Cherukuri P, Maskeri B, Hansen NF, Mullikin JC, Blakesley RW, Bouffard GG; NISC Comparative Sequencing Program, Gyapay G, Rieger S, Tönshoff B, Kern I, Soliman NA, Neuhaus TJ, Swoboda KJ, Kayserili H, Gallagher TE, Lewis RA, Bergmann C, Otto EA, Saunier S, Scambler PJ, Beales PL, Gleeson JG, Maher ER, Attié-Bitach T, Dollfus H, Johnson CA, Green ED, Gibbs RA, Hildebrandt F, Pierce EA, Katsanis N
Citation:
Nat Genet. 2011 Jan 23. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Ciliary dysfunction leads to a broad range of overlapping phenotypes, collectively termed ciliopathies. This grouping is...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Davis EE, Zhang Q, Liu Q, Diplas BH, Davey LM, Hartley J, Stoetzel C, Szymanska K, Ramaswami G, Logan CV, Muzny DM, Young AC, Wheeler DA, Cruz P, Morgan M, Lewis LR, Cherukuri P, Maskeri B, Hansen NF, Mullikin JC, Blakesley RW, Bouffard GG; NISC Comparative Sequencing Program, Gyapay G, Rieger S, Tönshoff B, Kern I, Soliman NA, Neuhaus TJ, Swoboda KJ, Kayserili H, Gallagher TE, Lewis RA, Bergmann C, Otto EA, Saunier S, Scambler PJ, Beales PL, Gleeson JG, Maher ER, Attié-Bitach T, Dollfus H, Johnson CA, Green ED, Gibbs RA, Hildebrandt F, Pierce EA, Katsanis N. TTC21B contributes both causal and modifying alleles across the ciliopathy spectrum. Nat Genet. 2011 Jan 23. [Epub ahead of print].

Tubulogenesis in a simple cell cord requires the formation of bi-apical cells through two discrete Par domains

Authors:
Denker E, Boccina I, Jiang D
Citation:
Development. 2013 Jun 12. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Apico-basal polarization is a crucial step in the de novo formation of biological tubes. In Ciona notochord, tubulogenesis...
Delivery Method:
Microinjection
Organism or Cell Type:
Ciona
Citation Extract:
Denker E, Boccina I, Jiang D. Tubulogenesis in a simple cell cord requires the formation of bi-apical cells through two discrete Par domains. Development. 2013 Jun 12. [Epub ahead of print].

Vascular cell adhesion molecule 1 (VCAM-1) activation of endothelial cell matrix metalloproteinases: role of reactive oxygen species

Authors:
Deem TL, Cook-Mills JM
Citation:
Blood. 2004 Oct 15;104(8):2385-93. Epub 2004 Jul 20
Epub:
Not Epub
Abstract:
Lymphocytes bound at endothelial cell junctions extravasate within minutes. Lymphocyte-endothelial cell binding is mediated by...
Delivery Method:
Special Delivery
Organism or Cell Type:
cell culture: mouse mHEVc
Citation Extract:
Deem TL, Cook-Mills JM. Vascular cell adhesion molecule 1 (VCAM-1) activation of endothelial cell matrix metalloproteinases: role of reactive oxygen species. Blood. 2004 Oct 15;104(8):2385-93. Epub 2004 Jul 20.

XIAP as target for therapeutic apoptosis in prostate cancer

Authors:
Devi GR
Citation:
Drug News Perspect. 2004 Mar;17(2):127-34
Epub:
Not Epub
Abstract:
Progression to androgen independence combined with chemotherapy resistance remains one of the primary obstacles to the...
Citation Extract:
Devi GR. XIAP as target for therapeutic apoptosis in prostate cancer. Drug News Perspect. 2004 Mar;17(2):127-34.

Xiro homeoproteins coordinate cell cycle exit and primary neuron formation by upregulating neuronal-fate repressors and downregulating the cell-cycle inhibitor XGadd45-gamma

Authors:
de la Calle-Mustienes E, Glavic A, Modolell J, Gomez-Skarmeta JL
Citation:
Mech Dev. 2002 Nov;119(1):69-80
Epub:
Not Epub
Abstract:
The iroquois (iro) homeobox genes participate in many developmental processes both in vertebrates and invertebrates, among them...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
de la Calle-Mustienes E, Glavic A, Modolell J, Gomez-Skarmeta JL. Xiro homeoproteins coordinate cell cycle exit and primary neuron formation by upregulating neuronal-fate repressors and downregulating the cell-cycle inhibitor XGadd45-gamma. Mech Dev. 2002 Nov;119(1):69-80.

Zebrafish sip1a and sip1b are essential for normal axial and neural patterning

Authors:
Delalande JM, Guyote ME, Smith CM, Shepherd IT
Citation:
Dev Dyn. 2008 Mar 19;237(4):1060-1069 [Epub ahead of print]
Epub:
Not Epub
Abstract:
Smad-interacting protein-1 (SIP1) has been implicated in the development of Mowat-Wilson syndrome whose patients exhibit...
Organism or Cell Type:
zebrafish
Citation Extract:
Delalande JM, Guyote ME, Smith CM, Shepherd IT. Zebrafish sip1a and sip1b are essential for normal axial and neural patterning. Dev Dyn. 2008 Mar 19;237(4):1060-1069 [Epub ahead of print].

Zebrafish Tsc1 Reveals Functional Interactions Between the Cilium and the TOR Pathway

Authors:
Dibella LM, Park A, Sun Z
Citation:
Hum Mol Genet. 2008 Nov 13. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The cell surface organelle called the cilium is essential for preventing kidney cyst formation and for establishing left-right...
Organism or Cell Type:
zebrafish
Citation Extract:
Dibella LM, Park A, Sun Z. Zebrafish Tsc1 Reveals Functional Interactions Between the Cilium and the TOR Pathway. Hum Mol Genet. 2008 Nov 13. [Epub ahead of print].

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