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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12378 scientific papers returned from the database with the search filters currently being used below.

Genetic analysis of fin development in zebrafish identifies furin and hemicentin1 as potential novel fraser syndrome disease genes

Authors:
Carney TJ, Feitosa NM, Sonntag C, Slanchev K, Kluger J, Kiyozumi D, Gebauer JM, Coffin Talbot J, Kimmel CB, Sekiguchi K, Wagener R, Schwarz H, Ingham PW, Hammerschmidt M
Citation:
PLoS Genet. 2010 Apr 15;6(4):e1000907
Epub:
Not Epub
Abstract:
Using forward genetics, we have identified the genes mutated in two classes of zebrafish fin mutants. The mutants of the first...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Carney TJ, Feitosa NM, Sonntag C, Slanchev K, Kluger J, Kiyozumi D, Gebauer JM, Coffin Talbot J, Kimmel CB, Sekiguchi K, Wagener R, Schwarz H, Ingham PW, Hammerschmidt M. Genetic analysis of fin development in zebrafish identifies furin and hemicentin1 as potential novel fraser syndrome disease genes. PLoS Genet. 2010 Apr 15;6(4):e1000907.

IGF signaling between blastema and wound epidermis is required for fin regeneration

Authors:
Chablais F, Jazwinska A
Citation:
Development. 2010 Mar;137(6):871-9
Epub:
Not Epub
Abstract:
In mammals, the loss of a limb is irreversible. By contrast, urodele amphibians and teleost fish are capable of nearly perfect...
Organism or Cell Type:
zebrafish
Citation Extract:
Chablais F, Jazwinska A. IGF signaling between blastema and wound epidermis is required for fin regeneration. Development. 2010 Mar;137(6):871-9.

Impairing Otp homeodomain function in oral ectoderm cells affects skeletogenesis in sea urchin embryos.

Authors:
Cavalieri V, Spinelli G, Di Bernardo M.
Citation:
Dev Biol. 2003 Oct 1;262(1):107-18.
Epub:
Not Epub
Abstract:
In the sea urchin embryo skeletogenesis is the result of a complex series of molecular and cellular events that coordinate the...
Delivery Method:
Microinjection
Organism or Cell Type:
Sea urchin, Strongylocentrotus purpuratus
Citation Extract:
Cavalieri V, Spinelli G, Di Bernardo M.. Impairing Otp homeodomain function in oral ectoderm cells affects skeletogenesis in sea urchin embryos.. Dev Biol. 2003 Oct 1;262(1):107-18..

In vitro antisense therapeutics for a deep intronic mutation causing Neurofibromatosis type 2

Authors:
Castellanos EC, Rosas I, Solanes A, Bielsa I, Lazaro C, Carrato C, Hostalot C, Prades P, Roca-Ribas F, Blanco I, Serra E
Citation:
Eur J Hum Genet. 2012;[Epub ahead of print] doi:10.1038/ejhg.2012.261
Epub:
Not Epub
Abstract:
Neurofibromatosis type 2 (NF2) is an autosomal-dominant disorder affecting about 1:33 000 newborns, mainly characterized by the...
Organism or Cell Type:
cell culture: human fibroblasts
Citation Extract:
Castellanos EC, Rosas I, Solanes A, Bielsa I, Lazaro C, Carrato C, Hostalot C, Prades P, Roca-Ribas F, Blanco I, Serra E. In vitro antisense therapeutics for a deep intronic mutation causing Neurofibromatosis type 2. Eur J Hum Genet. 2012;[Epub ahead of print] doi:10.1038/ejhg.2012.261.

In vivo birthdating by BAPTISM reveals that trigeminal sensory neuron diversity depends on early neurogenesis

Authors:
Caron SJ, Prober D, Choy M, Schier AF
Citation:
Development. 2008 Oct;135(19):3259-69. Epub 2008 Aug 28
Epub:
Not Epub
Abstract:
Among sensory systems, the somatic sense is exceptional in its ability to detect a wide range of chemical, mechanical and...
Organism or Cell Type:
zebrafish
Citation Extract:
Caron SJ, Prober D, Choy M, Schier AF. In vivo birthdating by BAPTISM reveals that trigeminal sensory neuron diversity depends on early neurogenesis. Development. 2008 Oct;135(19):3259-69. Epub 2008 Aug 28.

Inactivation of serine protease Matriptase1a by its inhibitor Hai1 is required for epithelial integrity of the zebrafish epidermis

Authors:
Carney TJ, von der Hardt S, Sonntag C, Amsterdam A, Topczewski J, Hopkins N, Hammerschmidt M
Citation:
Development. 2007 Oct;134(19):3461-71. Epub 2007 Aug 29
Epub:
Not Epub
Abstract:
Epithelial integrity requires the adhesion of cells to each other as well as to an underlying basement membrane. The modulation...
Organism or Cell Type:
zebrafish
Citation Extract:
Carney TJ, von der Hardt S, Sonntag C, Amsterdam A, Topczewski J, Hopkins N, Hammerschmidt M. Inactivation of serine protease Matriptase1a by its inhibitor Hai1 is required for epithelial integrity of the zebrafish epidermis. Development. 2007 Oct;134(19):3461-71. Epub 2007 Aug 29.

Increased expression of VEGF(121)/VEGF(165-189) ratio results in a significant enhancement of human prostate tumor angiogenesis

Authors:
Catena R, Muniz-Medina V, Moralejo B, Javierre B, Best CJ, Emmert-Buck MR, Green JE, Baker CC, Calvo A
Citation:
Int J Cancer. 2007 May 15;120(10):2096-109.
Epub:
Not Epub
Abstract:
Vascular endothelial growth factor (VEGF) is a proangiogenic factor upregulated in many tumors. The alternative splicing of...
Organism or Cell Type:
cell culture: human PC3, prostate cancer lines
Citation Extract:
Catena R, Muniz-Medina V, Moralejo B, Javierre B, Best CJ, Emmert-Buck MR, Green JE, Baker CC, Calvo A. Increased expression of VEGF(121)/VEGF(165-189) ratio results in a significant enhancement of human prostate tumor angiogenesis. Int J Cancer. 2007 May 15;120(10):2096-109..

Inhibition of the P2X7 Receptor Reduces Cystogenesis in PKD

Authors:
Chang MY, Lu JK, Tian YC, Chen YC, Hung CC, Huang YH, Chen YH, Wu MS, Yang CW, Cheng YC
Citation:
J Am Soc Nephrol. 2011 Jun 2. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The P2X7 receptor participates in purinergic signaling, which may promote the progression of ADPKD. We examined the effects of...
Organism or Cell Type:
zebrafish
Citation Extract:
Chang MY, Lu JK, Tian YC, Chen YC, Hung CC, Huang YH, Chen YH, Wu MS, Yang CW, Cheng YC. Inhibition of the P2X7 Receptor Reduces Cystogenesis in PKD. J Am Soc Nephrol. 2011 Jun 2. [Epub ahead of print].

Intraflagellar transport proteins are essential for cilia formation and for planar cell polarity

Authors:
Cao Y, Park A, Sun Z
Citation:
J Am Soc Nephrol. 2010 Aug;21(8):1326-33. Epub 2010 Jun 24
Epub:
Not Epub
Abstract:
The highly conserved intraflagellar transport (IFT) proteins are essential for cilia formation in multiple organisms, but...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Cao Y, Park A, Sun Z. Intraflagellar transport proteins are essential for cilia formation and for planar cell polarity. J Am Soc Nephrol. 2010 Aug;21(8):1326-33. Epub 2010 Jun 24.

Intrinsic differences between the superficial and deep layers of the Xenopus ectoderm control primary neuronal differentiation.

Authors:
Chalmers AD, Welchman D, Papalopulu N
Citation:
Dev Cell. 2002 Feb;2(2):171-82.
Epub:
Not Epub
Abstract:
In Xenopus, primary neurons differentiate early, in the deep layer of the neuroectoderm. In contrast, the neural precursors of...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Chalmers AD, Welchman D, Papalopulu N. Intrinsic differences between the superficial and deep layers of the Xenopus ectoderm control primary neuronal differentiation.. Dev Cell. 2002 Feb;2(2):171-82..

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