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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12378 scientific papers returned from the database with the search filters currently being used below.

The N-terminal region of CEP290 restores vision in a zebrafish model of human blindness

Authors:
Baye LM, Patrinostro X, Swaminathan S, Beck JS, Zhang Y, Stone EM, Sheffield VC, Slusarski DC
Citation:
Hum Mol Genet. 2011 Jan 21. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The gene coding for Centrosomal Protein 290 (CEP290), a large multi-domain protein, is the most frequently mutated gene...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Baye LM, Patrinostro X, Swaminathan S, Beck JS, Zhang Y, Stone EM, Sheffield VC, Slusarski DC. The N-terminal region of CEP290 restores vision in a zebrafish model of human blindness. Hum Mol Genet. 2011 Jan 21. [Epub ahead of print].

The Protooncogene c-Myc Is an Essential Regulator of Neural Crest Formation in Xenopus

Authors:
Bellmeyer A, Krase J, Lindgren J, LaBonne C
Citation:
Dev Cell. 2003 Jun;4(6):827-39
Epub:
Not Epub
Abstract:
The neural crest, a population of multipotent progenitor cells, is a defining feature of vertebrate embryos. Neural crest...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Bellmeyer A, Krase J, Lindgren J, LaBonne C. The Protooncogene c-Myc Is an Essential Regulator of Neural Crest Formation in Xenopus. Dev Cell. 2003 Jun;4(6):827-39.

The RNA-binding protein XSeb4R regulates maternal Sox3 at the posttranscriptional level during maternal-zygotic transition in Xenopus

Authors:
Bentaya S, Ghogomu SM, Vanhomwegen J, Van Campenhout C, Thelie A, Dhainaut M, Bellefroid E, Souopgui J
Citation:
Dev Biol. 2012 Jan 11. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The maternal-zygotic transition (MZT) is an embryonic event that overlaps with and plays key roles in primary germ layer...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Bentaya S, Ghogomu SM, Vanhomwegen J, Van Campenhout C, Thelie A, Dhainaut M, Bellefroid E, Souopgui J. The RNA-binding protein XSeb4R regulates maternal Sox3 at the posttranscriptional level during maternal-zygotic transition in Xenopus. Dev Biol. 2012 Jan 11. [Epub ahead of print].

The type I serine/threonine kinase receptor Alk8/Lost-a-fin is required for Bmp2b/7 signal transduction during dorsoventral patterning of the zebrafish embryo

Authors:
Bauer H, Lele Z, Rauch GJ, Geisler R, Hammerschmidt M
Citation:
Development 2001 128(6):849-858
Epub:
Not Epub
Abstract:
Ventral specification of mesoderm and ectoderm depends on signaling by members of the bone morphogenetic protein (Bmp) family....
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bauer H, Lele Z, Rauch GJ, Geisler R, Hammerschmidt M. The type I serine/threonine kinase receptor Alk8/Lost-a-fin is required for Bmp2b/7 signal transduction during dorsoventral patterning of the zebrafish embryo. Development 2001 128(6):849-858.

The zebrafish neckless mutation reveals a requirement for raldh2 in mesodermal signals that pattern the hindbrain

Authors:
Begemann G, Schilling TF, Rauch GJ, Geisler R, Ingham PW
Citation:
Development. 2001 Aug;128(16):3081-94
Epub:
Not Epub
Abstract:
We describe a new zebrafish mutation, neckless, and present evidence that it inactivates retinaldehyde dehydrogenase type 2, an...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Begemann G, Schilling TF, Rauch GJ, Geisler R, Ingham PW. The zebrafish neckless mutation reveals a requirement for raldh2 in mesodermal signals that pattern the hindbrain. Development. 2001 Aug;128(16):3081-94.

Therapeutic Potential of Splice-Switching Oligonucleotides

Authors:
Bauman J, Jearawiriyapaisarn N, Kole R
Citation:
Oligonucleotides. 2009 Jan 6. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Alternative splicing enables a single pre-messenger RNA transcript to yield multiple protein isoforms, making it a major...
Citation Extract:
Bauman J, Jearawiriyapaisarn N, Kole R. Therapeutic Potential of Splice-Switching Oligonucleotides. Oligonucleotides. 2009 Jan 6. [Epub ahead of print].

TIF1gamma controls erythroid cell fate by regulating transcription elongation

Authors:
Bai X, Kim J, Yang Z, Jurynec MJ, Akie TE, Lee J, LeBlanc J, Sessa A, Jiang H, DiBiase A, Zhou Y, Grunwald DJ, Lin S, Cantor AB, Orkin SH, Zon LI
Citation:
Cell. 2010 Jul 9;142(1):133-43
Epub:
Not Epub
Abstract:
Recent genome-wide studies have demonstrated that pausing of RNA polymerase II (Pol II) occurred on many vertebrate genes. By...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bai X, Kim J, Yang Z, Jurynec MJ, Akie TE, Lee J, LeBlanc J, Sessa A, Jiang H, DiBiase A, Zhou Y, Grunwald DJ, Lin S, Cantor AB, Orkin SH, Zon LI. TIF1gamma controls erythroid cell fate by regulating transcription elongation. Cell. 2010 Jul 9;142(1):133-43.

Transdermal use of phosphorodiamidate morpholino oligomer AVI-4472 inhibits cytochrome P450 3A2 activity in male rats

Authors:
Arora V, Hannah TL, Iversen PL, Brand RM
Citation:
Pharm Res. 2002 Oct;19(10):1465-70
Epub:
Not Epub
Abstract:
PURPOSE: To determine if dermal absorption of an antisense phosphorodiamidate Morpholino oligomers (PMO) can inhibit target...
Delivery Method:
transdermal
Organism or Cell Type:
Sprague Dawley rats & hairless CRL:SK1 mice
Citation Extract:
Arora V, Hannah TL, Iversen PL, Brand RM. Transdermal use of phosphorodiamidate morpholino oligomer AVI-4472 inhibits cytochrome P450 3A2 activity in male rats. Pharm Res. 2002 Oct;19(10):1465-70.

Triplex formation by morpholino oligodeoxyribonucleotides in the HER-2/neu promoter requires the pyrimidine motif

Authors:
Basye J, Trent JO, Gao D, Ebbinghaus SW
Citation:
Nucleic Acids Res 2001 Dec 1;29(23):4873-80
Epub:
Not Epub
Abstract:
Triplex-forming oligonucleotides (TFOs) are good candidates to be used as site-specific DNA-binding agents. Two obstacles...
Delivery Method:
not applicable
Organism or Cell Type:
not applicable
Citation Extract:
Basye J, Trent JO, Gao D, Ebbinghaus SW. Triplex formation by morpholino oligodeoxyribonucleotides in the HER-2/neu promoter requires the pyrimidine motif. Nucleic Acids Res 2001 Dec 1;29(23):4873-80.

Two highly related regulatory subunits of PP2A exert opposite effects on TGF-beta/Activin/Nodal signalling

Authors:
Batut J, Schmierer B, Cao J, Raftery LA, Hill CS, Howell M
Citation:
Development. 2008 Sep;135(17):2927-37
Epub:
Not Epub
Abstract:
We identify Balpha (PPP2R2A) and Bdelta (PPP2R2D), two highly related members of the B family of regulatory subunits of the...
Organism or Cell Type:
Xenopus
Citation Extract:
Batut J, Schmierer B, Cao J, Raftery LA, Hill CS, Howell M. Two highly related regulatory subunits of PP2A exert opposite effects on TGF-beta/Activin/Nodal signalling. Development. 2008 Sep;135(17):2927-37.

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