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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12378 scientific papers returned from the database with the search filters currently being used below.
There are 12378 scientific papers returned from the database with the search filters currently being used below.
Deep Learning Enables Discovery of a Short Nuclear Targeting Peptide for Efficient Delivery of Antisense Oligomers
Citation:
JACS Au. 2021;[Epub] doi:10.1021/jacsau.1c00327 Epub:
Not Epub Abstract:
Therapeutic macromolecules such as proteins and oligonucleotides can be highly efficacious but are often limited to... Delivery Method:
peptide-linked Organism or Cell Type:
cell culture: HeLa, mice Citation Extract: López-Vidal EM, Schissel CK, Mohapatra S, Bellovoda K, Wu C-L, Wood JA, Malmberg AB, Loas A, Gómez-Bombarelli R, Pentelute BL. Deep Learning Enables Discovery of a Short Nuclear Targeting Peptide for Efficient Delivery of Antisense Oligomers. JACS Au. 2021;[Epub] doi:10.1021/jacsau.1c00327. |
Mechanosensitive Notch-Dll4 and Klf2-Wnt9 signaling pathways intersect in guiding valvulogenesis in zebrafish
Citation:
Cell Rep. 2021 Oct 5;37(1):109782. doi: 10.1016/j.celrep.2021.109782 Epub:
Not Epub Abstract:
In the zebrafish embryo, the onset of blood flow generates fluid shear stress on endocardial cells, which are specialized... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Paolini A, Fontana F, Pham VC, Rödel CJ, Abdelilah-Seyfried S. Mechanosensitive Notch-Dll4 and Klf2-Wnt9 signaling pathways intersect in guiding valvulogenesis in zebrafish. Cell Rep. 2021 Oct 5;37(1):109782. doi: 10.1016/j.celrep.2021.109782. |
Cell-to-cell heterogeneity in Sox2 and Bra expression guides progenitor motility and destiny
Citation:
eLife. 2021;10:e66588 doi:10.7554/eLife.66588 Epub:
Not Epub Abstract:
Although cell-to-cell heterogeneity in gene and protein expression within cell populations has been widely documented, we know... Delivery Method:
electroporation Organism or Cell Type:
Coturnix japonica (quail) Citation Extract: Romanos M, Allio G, Roussigné M, Combres L, Escalas N, Soula C, Médevielle F, Steventon B, Trescases A, Bénazéraf B. Cell-to-cell heterogeneity in Sox2 and Bra expression guides progenitor motility and destiny. eLife. 2021;10:e66588 doi:10.7554/eLife.66588. |
SHANK3 conformation regulates direct actin binding and crosstalk with Rap1 signaling
Citation:
Curr Biol. 2021;[Epub] doi:10.1016/j.cub.2021.09.022 Epub:
Not Epub Abstract:
Actin-rich cellular protrusions direct versatile biological processes from cancer cell invasion to dendritic spine development... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Salomaa SI, Miihkinen M, Kremneva E, Paatero I, Lilja J, Jacquemet G, Vuorio J, Antenucci L, Kogan K, Hassani NF, Hollos P, Isomursu A, Vattulainen I, Coffey ET, Kreienkamp H-J, Lappalainen P, Ivaska J. SHANK3 conformation regulates direct actin binding and crosstalk with Rap1 signaling. Curr Biol. 2021;[Epub] doi:10.1016/j.cub.2021.09.022. |
The Secreted Protein Disulfide Isomerase Ag1 Lost by Ancestors of Poorly Regenerating Vertebrates Is Required for Xenopus laevis Tail Regeneration
Citation:
Front Cell Dev Biol. 2021;9:738940. doi:10.3389/fcell.2021.738940 Epub:
Not Epub Abstract:
Warm-blooded vertebrates regenerate lost limbs and their parts in general much worse than fishes and amphibians. We previously... Delivery Method:
microinjection, Vivo-Morpholino Organism or Cell Type:
Xenopus laevis Citation Extract: Ivanova AS, Tereshina MB, Araslanova KR, Martynova NY, Zaraisky AG. The Secreted Protein Disulfide Isomerase Ag1 Lost by Ancestors of Poorly Regenerating Vertebrates Is Required for Xenopus laevis Tail Regeneration. Front Cell Dev Biol. 2021;9:738940. doi:10.3389/fcell.2021.738940. |
The spliceosome factor sart3 regulates hematopoietic stem/progenitor cell development in zebrafish through the p53 pathway
Citation:
Cell Death Dis. 2021;12(10):906. doi:10.1038/s41419-021-04215-4 Epub:
Not Epub Abstract:
Hematopoietic stem cells (HSCs) possess the potential for self-renew and the capacity, throughout life, to differentiate into... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Zhao Y, Wu M, Li J, Meng P, Chen J, Huang, Xu J, Wen Z, Zhang W, Zhang Y. The spliceosome factor sart3 regulates hematopoietic stem/progenitor cell development in zebrafish through the p53 pathway. Cell Death Dis. 2021;12(10):906. doi:10.1038/s41419-021-04215-4. |
Mutations linked to loss of cell cycle control can render cells responsive to local differentiation cues
Citation:
microPublication Biology. 2021.10.17912/micropub.biology.000481. doi:10.17912/micropub.biology.000481 Epub:
Not Epub Abstract:
Cell behaviors such as survival, proliferation, and death are governed by a multitude of cues, both intrinsic and extrinsic. To... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Cerveny KL, Bronstein H, Hagen O, Lamb DB, Martin G, Tower I, Van Duzer A, Welch E, Varga M. Mutations linked to loss of cell cycle control can render cells responsive to local differentiation cues. microPublication Biology. 2021.10.17912/micropub.biology.000481. doi:10.17912/micropub.biology.000481. |
Transcriptome profile of the sinoatrial ring reveals conserved and novel genetic programs of the zebrafish pacemaker
Citation:
BMC Genomics. 2021 Oct 2;22(1):715. doi:10.1186/s12864-021-08016-z Epub:
Not Epub Abstract:
Background: Sinoatrial Node (SAN) is part of the cardiac conduction system, which controls the rhythmic contraction of the... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Minhas R, Loeffler-Wirth H, Siddiqui YH, Obrębski T, Vashisht S, Nahia KA, Paterek A, Brzozowska A, Bugajski L, Piwocka K, Korzh V, Binder H, Winata CL. Transcriptome profile of the sinoatrial ring reveals conserved and novel genetic programs of the zebrafish pacemaker. BMC Genomics. 2021 Oct 2;22(1):715. doi:10.1186/s12864-021-08016-z. |
Mycobacteriophage-antibiotic therapy promotes enhanced clearance of drug-resistant Mycobacterium abscessus
Citation:
Dis Model Mech. 2021 Sep 1;14(9):dmm049159. doi: 10.1242/dmm.049159. Epub 2021 Sep 16 Epub:
Not Epub Abstract:
Infection by multidrug-resistant Mycobacterium abscessus is increasingly prevalent in cystic fibrosis (CF) patients, leaving... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Johansen MD, Alcaraz M, Dedrick RM, Roquet-Banères F, Hamela C, Hatfull GF, Kremer L. Mycobacteriophage-antibiotic therapy promotes enhanced clearance of drug-resistant Mycobacterium abscessus. Dis Model Mech. 2021 Sep 1;14(9):dmm049159. doi: 10.1242/dmm.049159. Epub 2021 Sep 16. |
Glypican 4 mediates Wnt transport between germ layers via signaling filopodia
Citation:
J Cell Biol. 2021;220(12):e202009082. doi:10.1083/jcb.202009082 Epub:
Not Epub Abstract:
Glypicans influence signaling pathways by regulating morphogen trafficking and reception. However, the underlying mechanisms in... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Hu B Rodriguez JJ Balaraju AK, Gao Y, Nguyen NT, Steen H, Suhaib S, Chen S, Lin F. Glypican 4 mediates Wnt transport between germ layers via signaling filopodia. J Cell Biol. 2021;220(12):e202009082. doi:10.1083/jcb.202009082. |