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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12390 scientific papers returned from the database with the search filters currently being used below.
There are 12390 scientific papers returned from the database with the search filters currently being used below.
Interplay of TRIM2E3 Ubiquitin Ligase and ALIX/ESCRT Complex: Control of Developmental Plasticity During Early Neurogenesis
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Citation:
Cells. 2020;9(7):2073-4409 doi:10.3390/cells9071734 Epub:
Not Epub Abstract:
Tripartite motif 2 (TRIM2) drives neurite outgrowth and polarization, is involved in axon specification, and confers... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Lokapally A, Neuhaus H, Herfurth J, Hollemann T. Interplay of TRIM2E3 Ubiquitin Ligase and ALIX/ESCRT Complex: Control of Developmental Plasticity During Early Neurogenesis. Cells. 2020;9(7):2073-4409 doi:10.3390/cells9071734. |
Chitosan-Shelled Nanobubbles Irreversibly Encapsulate Morpholino Conjugate Antisense Oligonucleotides and Are Ineffective for Phosphorodiamidate Morpholino-Mediated Gene Silencing of DUX4
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Citation:
Nucleic Acid Ther. 2020 Jul 13. doi: 10.1089/nat.2020.0862. Online ahead of print Epub:
Yes Abstract:
Orphan drugs, including antisense oligonucleotides (AONs), siRNAs/miRNAs, Cas9 nuclease, and recombinant genes, have recently... Delivery Method:
chitosan nanobubble Organism or Cell Type:
cell culture Citation Extract: Falzarano MS, Argenziano M, Marsollier AC, Mariot V, Rossi D, Selvatici R, Dumonceaux J, Cavalli R, Ferlini A. Chitosan-Shelled Nanobubbles Irreversibly Encapsulate Morpholino Conjugate Antisense Oligonucleotides and Are Ineffective for Phosphorodiamidate Morpholino-Mediated Gene Silencing of DUX4. Nucleic Acid Ther. 2020 Jul 13. doi: 10.1089/nat.2020.0862. Online ahead of print. |
CFTR Depletion Confers Hypersusceptibility to Mycobacterium fortuitum in a Zebrafish Model
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Citation:
Front Cell Infect Microbiol. 2020;10:357. doi:10.3389/fcimb.2020.00357 Epub:
Not Epub Abstract:
The Mycobacterium fortuitum complex comprises several closely related species, causing pulmonary and extra-pulmonary infections... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Johansen MD, Kremer L. CFTR Depletion Confers Hypersusceptibility to Mycobacterium fortuitum in a Zebrafish Model. Front Cell Infect Microbiol. 2020;10:357. doi:10.3389/fcimb.2020.00357. |
Targeted Delivery of Antisense Oligonucleotides Using Neurotensin Peptide
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Citation:
J Med Chem. 2020 Jul 17. doi:10.1021/acs.jmedchem.0c00840. Online ahead of print Epub:
Not Epub Abstract:
Despite recent advances, targeted delivery of therapeutic oligonucleotide to extra-hepatic tissues continues to be a... Delivery Method:
peptide-linked, intracerebroventricular (i.c.v.) injection in mice Organism or Cell Type:
cell culture: HEK293, mice Citation Extract: Nikan M, Tanowitz M, Dwyer CA, Jackson M, Gaus H, Swayze E, Rigo F, Seth PP, Prakash TP. Targeted Delivery of Antisense Oligonucleotides Using Neurotensin Peptide. J Med Chem. 2020 Jul 17. doi:10.1021/acs.jmedchem.0c00840. Online ahead of print. |
Kowalczyk I, Lee C, Schuster E, Hoeren J, Trivigno V, Riedel L, Goerne J, Wallingford JB, Hammes-Lewin A, Feistel K
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Citation:
bioRxiv. 2020;[preprint] doi:10.1101/2020.07.15.205252 Epub:
Not Epub Abstract:
Recent studies have revealed that pathogenic mutations in the endocytic receptor LRP2 in humans are associated with severe... Delivery Method:
microinjection Organism or Cell Type:
Xenopus Citation Extract: Neural tube closure requires the endocytic receptor Lrp2 and its functional interaction with intracellular scaffolds. Kowalczyk I, Lee C, Schuster E, Hoeren J, Trivigno V, Riedel L, Goerne J, Wallingford JB, Hammes-Lewin A, Feistel K. bioRxiv. 2020;[preprint] doi:10.1101/2020.07.15.205252 . |
VLRs expression were significantly affected by complement C3 knockdown morphants in Lampetra morii
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Citation:
Fish Shellfish Immun. 2020;[Epub ahead of print] doi:10.1016/j.fsi.2020.07.013 Epub:
Yes Abstract:
The complement component 3 of the lamprey, a jawless vertebrate, functions as an opsonin during the phagocytosis of rabbit red... Delivery Method:
microinjection Organism or Cell Type:
Lampetra morii (lamprey) Citation Extract: Li J, Liu H, Ma Q, Song X, Pang Y, Su P, Sun F, Gou M, Lu J, Shan Y, Guan H, Liu X, Li Q, Han Y. VLRs expression were significantly affected by complement C3 knockdown morphants in Lampetra morii. Fish Shellfish Immun. 2020;[Epub ahead of print] doi:10.1016/j.fsi.2020.07.013. |
Wang X, Dunlap K, Satterfield M, Frank J, Li X, Ying W, Burghardt R, Johnson GA, Wu G, Antoniazzi AQ, Nett TM, Hansen TR, Bazer FW
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Citation:
Biol Reprod. 2012;87(suppl 1)394. doi:10.1093/biolreprod/87.s1.394 Epub:
Not Epub Abstract:
Arginine (Arg), a nutritionally essential amino acid for conceptus development, can be metabolized to nitric oxide (NO) and... Delivery Method:
bathing in uterine lumen Organism or Cell Type:
Ovis aries (sheep) conceptus Citation Extract: Effects of In Vivo Knockdown of Translation of Arginine-Associated Gene Transcripts in Conceptus Trophectoderm on Growth, Development, and Gene Expression by Ovine Conceptuses
. Wang X, Dunlap K, Satterfield M, Frank J, Li X, Ying W, Burghardt R, Johnson GA, Wu G, Antoniazzi AQ, Nett TM, Hansen TR, Bazer FW. Biol Reprod. 2012;87(suppl 1)394. doi:10.1093/biolreprod/87.s1.394. |
Sensory Neuroblast Quiescence Dependson Vascular Cytoneme Contacts and Sensory Neuronal Differentiation Requires Initiation of Blood Flow
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Citation:
Cell Rep. 2020;32:107903. doi:10.1016/j.celrep.2020.107903 Epub:
Not Epub Abstract:
In many organs, stem cell function depends on communication with their niche partners. Cranial sensory neurons develop in... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Taberner L, Banñó A, Alsina B. Sensory Neuroblast Quiescence Dependson Vascular Cytoneme Contacts and Sensory Neuronal Differentiation Requires Initiation of Blood Flow. Cell Rep. 2020;32:107903. doi:10.1016/j.celrep.2020.107903. |
IRSp53 controls plasma membrane shape and polarized transport at the nascent lumen in epithelial tubules
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Citation:
Nat Commun. 2020;11(1):3516 doi:10.1038/s41467-020-17091-x Epub:
Not Epub Abstract:
It is unclear whether the establishment of apical–basal cell polarity during the generation of epithelial lumens requires... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Bisi S, Marchesi S, Rizvi A, Carra D, Beznoussenko GV, Ferrara I, Deflorian G, Mironov A, Bertalot G, Pisati F, Oldani A, Cattaneo A, Saberamoli G, Pece S, Viale G, Bachi A, Tripodo C, Scita G, Disanza A. IRSp53 controls plasma membrane shape and polarized transport at the nascent lumen in epithelial tubules. Nat Commun. 2020;11(1):3516 doi:10.1038/s41467-020-17091-x. |
Antagonistic Activities of Vegfr3/Flt4 and Notch1b Fine-tune Mechanosensitive Signaling during Zebrafish Cardiac Valvulogenesis
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Citation:
Cell Rep. 2020;32(2):107833. doi:10.1016/j.celrep.2020.107883 Epub:
Not Epub Abstract:
The formation of cardiac valves depends on mechanical forces exerted by blood flow. Endocardial cells lining the interior of... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Fontana F, Haack T, Reichenbach M, Knaus P, Puceat M, Abdelilah-Seyfried SA. Antagonistic Activities of Vegfr3/Flt4 and Notch1b Fine-tune Mechanosensitive Signaling during Zebrafish Cardiac Valvulogenesis. Cell Rep. 2020;32(2):107833. doi:10.1016/j.celrep.2020.107883. |