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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12378 scientific papers returned from the database with the search filters currently being used below.

Tmed10 deficiency results in impaired exocrine pancreatic differentiation in zebrafish larvae

Authors:
Tao Z, Yang D, Ni R
Citation:
Dev Biol. 2023 Aug 17:S0012-1606(23)00142-2. doi: 10.1016/j.ydbio.2023.08.003. Online ahead of print
Epub:
Yes
Abstract:
Transmembrane p24 trafficking protein 10 (TMED10) is a conserved vesicle trafficking protein. It is dysregulated in Alzheimer...
Link:
https://www.sciencedirect.com/science/article/abs/pii/S0012160623001422
Organism or Cell Type:
zebrafish
Citation Extract:
Tao Z, Yang D, Ni R. Tmed10 deficiency results in impaired exocrine pancreatic differentiation in zebrafish larvae. Dev Biol. 2023 Aug 17:S0012-1606(23)00142-2. doi: 10.1016/j.ydbio.2023.08.003. Online ahead of print.

Protocol for constructing GQD-PMO functionalized FET-biosensor for ultrasensitive exosomal miRNA detection

Authors:
Li K, Liang C, Pan Y, Mei L, Zhang GJ
Citation:
STAR Protoc. 2023 Sep 15;4(3):102516. doi: 10.1016/j.xpro.2023.102516. Epub 2023 Aug 16. PMID: 37590152; PMCID: PMC10461019
Epub:
Not Epub
Abstract:
Here, we present a protocol for constructing an ultrasensitive biosensor for exosomal-miRNA detection. We describe steps for...
Link:
https://pmc.ncbi.nlm.nih.gov/articles/PMC10461019/
Citation Extract:
Li K, Liang C, Pan Y, Mei L, Zhang GJ. Protocol for constructing GQD-PMO functionalized FET-biosensor for ultrasensitive exosomal miRNA detection. STAR Protoc. 2023 Sep 15;4(3):102516. doi: 10.1016/j.xpro.2023.102516. Epub 2023 Aug 16. PMID: 37590152; PMCID: PMC10461019.

Maternal RNA binding protein with multiple splicing 2 (RBPMS2) is involved in mouse blastocyst formation through the bone morphogenetic protein pathway

Authors:
Zhou C, Zheng L, Teng H, Yang Y, Ma R, Wang S, Yang Y, Jing J, Li M, Wu R, Chen L, Yao B
Citation:
Reprod Biomed Online. 2023 May 25;47(4):103238. doi: 10.1016/j.rbmo.2023.05.010. Online ahead of print
Epub:
Not Epub
Abstract:
Research question: Is early embryo development in mice influenced by RNA binding protein with multiple splicing 2 (RBPMS2), a...
Link:
https://www.rbmojournal.com/article/S1472-6483(23)00336-X/fulltext
Delivery Method:
microinjection
Organism or Cell Type:
mouse zygote
Citation Extract:
Zhou C, Zheng L, Teng H, Yang Y, Ma R, Wang S, Yang Y, Jing J, Li M, Wu R, Chen L, Yao B. Maternal RNA binding protein with multiple splicing 2 (RBPMS2) is involved in mouse blastocyst formation through the bone morphogenetic protein pathway. Reprod Biomed Online. 2023 May 25;47(4):103238. doi: 10.1016/j.rbmo.2023.05.010. Online ahead of print.

Cfdp1 Is Essential for Cardiac Development and Function

Authors:
Giardoglou P, Deloukas P, Dedoussis G, Beis D
Citation:
Cells. 2023 Aug 3;12(15):1994. doi: 10.3390/cells12151994
Epub:
Not Epub
Abstract:
Cardiovascular diseases (CVDs) are the prevalent cause of mortality worldwide. A combination of environmental and genetic...
Link:
https://www.mdpi.com/2073-4409/12/15/1994
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Giardoglou P, Deloukas P, Dedoussis G, Beis D. Cfdp1 Is Essential for Cardiac Development and Function. Cells. 2023 Aug 3;12(15):1994. doi: 10.3390/cells12151994.

β-Amyloid targeting nanodrug for neuron-specific delivery of nucleic acids in Alzheimer's disease mouse models

Authors:
Israel LL, Sun T, Braubach O, Cox A, Shatalova ES, Rashid HM, Galstyan A, Grodzinski Z, Song XY, Chepurna O, Ljubimov VA, Chiechi A, Sharma S, Phebus C, Wang Y, Ljubimova JY, Black KL, Holler E
Citation:
J Control Release. 2023 Aug 17;361:636-658. doi: 10.1016/j.jconrel.2023.08.001. Online ahead of print
Epub:
Not Epub
Abstract:
Delivery of therapeutic substances into the brain poses a significant challenge in the treatment of neurological disorders....
Link:
https://www.sciencedirect.com/science/article/pii/S0168365923004972
Delivery Method:
nanoparticle
Organism or Cell Type:
mice
Citation Extract:
Israel LL, Sun T, Braubach O, Cox A, Shatalova ES, Rashid HM, Galstyan A, Grodzinski Z, Song XY, Chepurna O, Ljubimov VA, Chiechi A, Sharma S, Phebus C, Wang Y, Ljubimova JY, Black KL, Holler E. β-Amyloid targeting nanodrug for neuron-specific delivery of nucleic acids in Alzheimer's disease mouse models. J Control Release. 2023 Aug 17;361:636-658. doi: 10.1016/j.jconrel.2023.08.001. Online ahead of print.

Matriptase-dependent epidermal pre-neoplasm in zebrafish embryos caused by a combination of hypotonic stress and epithelial polarity defects

Authors:
Hatzold J, Nett V, Brantsch S, Zhang J-L, Armistead J, Wessendorf H, Stephens R, Humbert RO, Iden S, Hammerschmidt M
Citation:
PLoS Genet. 2023;19(8):e1010873. doi:10.1371/journal.pgen.1010873
Epub:
Not Epub
Abstract:
Aberrantly up-regulated activity of the type II transmembrane protease Matriptase-1 has been associated with the development...
Link:
https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1010873
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hatzold J, Nett V, Brantsch S, Zhang J-L, Armistead J, Wessendorf H, Stephens R, Humbert RO, Iden S, Hammerschmidt M. Matriptase-dependent epidermal pre-neoplasm in zebrafish embryos caused by a combination of hypotonic stress and epithelial polarity defects. PLoS Genet. 2023;19(8):e1010873. doi:10.1371/journal.pgen.1010873.

Prickle planar cell polarity protein 1 involved in the pathogenesis of skeletal class Ⅲ malocclusion

Authors:
Zhang CC, Ma L, Zhou X, Fan LW, Pan YC
Citation:
Zhonghua Kou Qiang Yi Xue Za Zhi. 2023 Aug 9;58(8):799-808. Chinese. doi: 10.3760/cma.j.cn112144-20230404-00135. PMID: 37550040
Epub:
Not Epub
Abstract:
Objective: To explore the mechanisms of prickle planar cell polarity protein 1 (PRICKLE1) involved in the occurrence of...
Link:
https://rs.yiigle.com/cmaid/1468270
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhang CC, Ma L, Zhou X, Fan LW, Pan YC. Prickle planar cell polarity protein 1 involved in the pathogenesis of skeletal class Ⅲ malocclusion. Zhonghua Kou Qiang Yi Xue Za Zhi. 2023 Aug 9;58(8):799-808. Chinese. doi: 10.3760/cma.j.cn112144-20230404-00135. PMID: 37550040.

Deletion of miR-146a enhances therapeutic protein restoration in model of dystrophin exon skipping

Authors:
McCormack NM, Calabrese KA, Sun CM, Tully CB, Heier CR, Fiorillo AA
Citation:
Mol Ther Nucleic Acids. 2024 May 24;35(3):102228. doi: 10.1016/j.omtn.2024.102228. eCollection 2024 Sep 10. PMID: 38975000
Epub:
Not Epub
Abstract:
Duchenne muscular dystrophy (DMD) is a progressive muscle disease caused by the absence of dystrophin protein. One current DMD...
Link:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11225849/
Delivery Method:
intramuscular (i.m.) injection
Organism or Cell Type:
mice
Citation Extract:
McCormack NM, Calabrese KA, Sun CM, Tully CB, Heier CR, Fiorillo AA. Deletion of miR-146a enhances therapeutic protein restoration in model of dystrophin exon skipping. Mol Ther Nucleic Acids. 2024 May 24;35(3):102228. doi: 10.1016/j.omtn.2024.102228. eCollection 2024 Sep 10. PMID: 38975000.

Neuronal migration prevents spatial competition in retinal morphogenesis

Authors:
Rocha-Martins M, Nerli E, Kretzschmar J, Weigert M, Icha J, Myers EW, Norden C
Citation:
Nature. 2023:[Epub ahead of print]. doi:10.1038/s41586-023-06392-y
Epub:
Yes
Abstract:
The concomitant occurrence of tissue growth and organization is a hallmark of organismal development. This often means that...
Link:
https://www.nature.com/articles/s41586-023-06392-y
Organism or Cell Type:
zebrafish
Citation Extract:
Rocha-Martins M, Nerli E, Kretzschmar J, Weigert M, Icha J, Myers EW, Norden C. Neuronal migration prevents spatial competition in retinal morphogenesis. Nature. 2023:[Epub ahead of print]. doi:10.1038/s41586-023-06392-y.

Unreprogrammed H3K9me3 prevents minor zygotic genome activation and lineage commitment in SCNT embryos

Authors:
Xu R, Zhu Q, Zhao Y, Chen M, Yang L, Shen S, Yang G, Shi Z, Zhang X, Shi Q, Kou X, Zhao Y, Wang H, Jiang C, Li C, Gao S, Liu X
Citation:
Nat Commun. 2023;14:4807. doi:10.1038/s41467-023-40496-3
Epub:
Not Epub
Abstract:
Somatic cell nuclear transfer (SCNT) can be used to reprogram differentiated somatic cells to a totipotent state but has poor...
Link:
https://www.nature.com/articles/s41467-023-40496-3
Delivery Method:
microinjection
Organism or Cell Type:
mouse zygote
Citation Extract:
Xu R, Zhu Q, Zhao Y, Chen M, Yang L, Shen S, Yang G, Shi Z, Zhang X, Shi Q, Kou X, Zhao Y, Wang H, Jiang C, Li C, Gao S, Liu X. Unreprogrammed H3K9me3 prevents minor zygotic genome activation and lineage commitment in SCNT embryos. Nat Commun. 2023;14:4807. doi:10.1038/s41467-023-40496-3.

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