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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12378 scientific papers returned from the database with the search filters currently being used below.

CircME1 promotes aerobic glycolysis and sunitinib resistance of clear cell renal cell carcinoma through cis-regulation of ME1

Authors:
Zhang MX, Wang JL, Mo CQ, Mao XP, Feng ZH, Li JY, Lin HS, Song HD, Xu QH, Wang YH, Lu J, Wei JH, Han H, Chen W, Mao HP, Luo JH, Chen ZH
Citation:
Oncogene. 2022 Jul 7. doi: 10.1038/s41388-022-02386-8. Online ahead of print
Epub:
Not Epub
Abstract:
Circular RNAs (circRNAs) play critical roles in clear cell renal cell carcinoma (ccRCC). However, their involvement in...
Delivery Method:
electroporation
Organism or Cell Type:
cell culture
Citation Extract:
Zhang MX, Wang JL, Mo CQ, Mao XP, Feng ZH, Li JY, Lin HS, Song HD, Xu QH, Wang YH, Lu J, Wei JH, Han H, Chen W, Mao HP, Luo JH, Chen ZH. CircME1 promotes aerobic glycolysis and sunitinib resistance of clear cell renal cell carcinoma through cis-regulation of ME1. Oncogene. 2022 Jul 7. doi: 10.1038/s41388-022-02386-8. Online ahead of print.

Long-Term Systemic Treatment of a Mouse Model Displaying Chronic FSHD-like Pathology with Antisense Therapeutics That Inhibit DUX4 Expression

Authors:
Lu-Nguyen N, Dickson G, Malerba A, Popplewell L
Citation:
Biomedicines. 2022 Jul 7;10(7):1623. doi: 10.3390/biomedicines10071623
Epub:
Not Epub
Abstract:
Silencing the expression of the double homeobox 4 (DUX4) gene offers great potential for the treatment of facioscapulohumeral...
Delivery Method:
Vivo-Morpholino i.p. injection
Organism or Cell Type:
mice
Citation Extract:
Lu-Nguyen N, Dickson G, Malerba A, Popplewell L. Long-Term Systemic Treatment of a Mouse Model Displaying Chronic FSHD-like Pathology with Antisense Therapeutics That Inhibit DUX4 Expression. Biomedicines. 2022 Jul 7;10(7):1623. doi: 10.3390/biomedicines10071623.

Irf2bp2a regulates liver development via stabilizing P53 protein in zebrafish

Authors:
Yan L, Gao S, Zhu J, Zhou J
Citation:
Biochim Biophys Acta Gen Subj. 2022 Oct;1866(10):130186. doi: 10.1016/j.bbagen.2022.130186. Epub 2022 Jun 7
Epub:
Not Epub
Abstract:
Zebrafish irf2bp2a, an ortholog of human IRF2BP2, is specifically expressed in the developing liver at growth stage. As a multi...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Yan L, Gao S, Zhu J, Zhou J. Irf2bp2a regulates liver development via stabilizing P53 protein in zebrafish. Biochim Biophys Acta Gen Subj. 2022 Oct;1866(10):130186. doi: 10.1016/j.bbagen.2022.130186. Epub 2022 Jun 7.

Banp regulates DNA damage response and chromosome segregation during the cell cycle in zebrafish retina

Authors:
Babu S, Takeuchi Y, Masai I
Citation:
Elife. 2022 Aug 9;11:e74611. doi: 10.7554/eLife.74611
Epub:
Not Epub
Abstract:
Btg3-associated nuclear protein (Banp) was originally identified as a nuclear matrix-associated region (MAR)-binding protein...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Babu S, Takeuchi Y, Masai I. Banp regulates DNA damage response and chromosome segregation during the cell cycle in zebrafish retina. Elife. 2022 Aug 9;11:e74611. doi: 10.7554/eLife.74611.

Ankle2 deficiency-associated microcephaly and spermatogenesis defects in zebrafish are alleviated by heterozygous deletion of vrk1

Authors:
Apridita Sebastian W, Shiraishi H, Shimizu N, Umeda R, Lai S, Ikeuchi M, Morisaki I, Yano S, Yoshimura A, Hanada R, Hanada T
Citation:
Biochem Biophys Res Commun. 2022 Oct 8;624:95-101. doi: 10.1016/j.bbrc.2022.07.070. Epub 2022 Jul 31. PMID: 35940133
Epub:
Not Epub
Abstract:
Autosomal recessive primary microcephaly (MCPH) is a rare congenital disorder characterized by a below average brain volume at...
Organism or Cell Type:
zebrafish
Citation Extract:
Apridita Sebastian W, Shiraishi H, Shimizu N, Umeda R, Lai S, Ikeuchi M, Morisaki I, Yano S, Yoshimura A, Hanada R, Hanada T. Ankle2 deficiency-associated microcephaly and spermatogenesis defects in zebrafish are alleviated by heterozygous deletion of vrk1. Biochem Biophys Res Commun. 2022 Oct 8;624:95-101. doi: 10.1016/j.bbrc.2022.07.070. Epub 2022 Jul 31. PMID: 35940133.

Sox11b regulates the migration and fate determination of Müller glia-derived progenitors during retina regeneration in zebrafish

Authors:
Song K, Lin Z, Cao L, Lu B, Chen Y, Zhang S, Lu J, Xu H
Citation:
Neural Regen Res. 2023 Feb;18(2):445-450. doi: 10.4103/1673-5374.346550
Epub:
Not Epub
Abstract:
The transcription factor Sox11 plays important roles in retinal neurogenesis during vertebrate eye development. However, its...
Delivery Method:
electroporation
Organism or Cell Type:
zebrafish
Citation Extract:
Song K, Lin Z, Cao L, Lu B, Chen Y, Zhang S, Lu J, Xu H. Sox11b regulates the migration and fate determination of Müller glia-derived progenitors during retina regeneration in zebrafish. Neural Regen Res. 2023 Feb;18(2):445-450. doi: 10.4103/1673-5374.346550.

Quantification of Idua Enzymatic Activity Combined with Observation of Phenotypic Change in Zebrafish Embryos Provide a Preliminary Assessment of Mutated idua Correlated with Mucopolysaccharidosis Type I

Authors:
Lin CY, Lin HY, Chuang CK, Zhang PH, Tu YR, Lin SP, Tsai HJ
Citation:
J Pers Med. 2022 Jul 23;12(8):1199. doi: 10.3390/jpm12081199
Epub:
Not Epub
Abstract:
Mucopolysaccharidosis type I (MPS I) is an inherited autosomal recessive disease resulting from mutation of the α-l-Iduronidase...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lin CY, Lin HY, Chuang CK, Zhang PH, Tu YR, Lin SP, Tsai HJ. Quantification of Idua Enzymatic Activity Combined with Observation of Phenotypic Change in Zebrafish Embryos Provide a Preliminary Assessment of Mutated idua Correlated with Mucopolysaccharidosis Type I. J Pers Med. 2022 Jul 23;12(8):1199. doi: 10.3390/jpm12081199.

The Core Splicing Factors EFTUD2, SNRPB and TXNL4A Are Essential for Neural Crest and Craniofacial Development

Authors:
Park BY, Tachi-Duprat M, Ihewulezi C, Devotta A, Saint-Jeannet JP
Citation:
J Dev Biol. 2022 Jul 8;10(3):29. doi: 10.3390/jdb10030029
Epub:
Not Epub
Abstract:
Mandibulofacial dysostosis (MFD) is a human congenital disorder characterized by hypoplastic neural-crest-derived craniofacial...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Park BY, Tachi-Duprat M, Ihewulezi C, Devotta A, Saint-Jeannet JP. The Core Splicing Factors EFTUD2, SNRPB and TXNL4A Are Essential for Neural Crest and Craniofacial Development. J Dev Biol. 2022 Jul 8;10(3):29. doi: 10.3390/jdb10030029.

CRMP2 and CRMP4 are required for the formation of commissural tracts in the developing zebrafish forebrain

Authors:
Guo Y, Oliveros CF, Ohshima T
Citation:
Dev Neurobiol. 2022 Aug 5. doi: 10.1002/dneu.22897. Online ahead of print
Epub:
Yes
Abstract:
Axonal connections between the two sides of the brain are essential for processing sensorimotor functions, especially in...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Guo Y, Oliveros CF, Ohshima T. CRMP2 and CRMP4 are required for the formation of commissural tracts in the developing zebrafish forebrain. Dev Neurobiol. 2022 Aug 5. doi: 10.1002/dneu.22897. Online ahead of print.

Kynurenine-3-monooxygenase expression is activated in the pancreatic endocrine cells by diabetes and its blockade improves glucose-stimulated insulin secretion

Authors:
Liu J, Bailbé D, Raynal S, Carbonne C, Zhen D, Dairou J, Gausseres B, Armanet M, Domet T, Pitasi CL, Movassat J, Lim CK, Guillemin GJ, Autier V, Kergoat M, Portha B
Citation:
Biochim Biophys Acta Mol Basis Dis. 2022 Jul 29:166509. doi: 10.1016/j.bbadis.2022.166509. Online ahead of print
Epub:
Not Epub
Abstract:
Type 2 diabetes is associated with an inflammatory phenotype in the pancreatic islets. We previously demonstrated that...
Organism or Cell Type:
organ culture: rat GK islets
Citation Extract:
Liu J, Bailbé D, Raynal S, Carbonne C, Zhen D, Dairou J, Gausseres B, Armanet M, Domet T, Pitasi CL, Movassat J, Lim CK, Guillemin GJ, Autier V, Kergoat M, Portha B. Kynurenine-3-monooxygenase expression is activated in the pancreatic endocrine cells by diabetes and its blockade improves glucose-stimulated insulin secretion. Biochim Biophys Acta Mol Basis Dis. 2022 Jul 29:166509. doi: 10.1016/j.bbadis.2022.166509. Online ahead of print.

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