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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12371 scientific papers returned from the database with the search filters currently being used below.

Evidence for dynamic and multiple roles for huntingtin in Ciona intestinalis

Authors:
Idris MM, Thorndyke MC, Brown ER
Citation:
Invert Neurosci. 2013 Jun 25. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Although mutations in the huntingtin gene (HTT) due to poly-Q expansion cause neuropathology in humans (Huntington's...
Organism or Cell Type:
Ciona intestinalis
Citation Extract:
Idris MM, Thorndyke MC, Brown ER. Evidence for dynamic and multiple roles for huntingtin in Ciona intestinalis. Invert Neurosci. 2013 Jun 25. [Epub ahead of print].

Gene expression profiles of transcription factors and signaling molecules in the ascidian embryo: towards a comprehensive understanding of gene networks

Authors:
Imai KS, Hino K, Yagi K, Satoh N, Satou Y
Citation:
Development. 2004 Aug;131(16):4047-58.
Epub:
Not Epub
Abstract:
Achieving a real understanding of animal development obviously requires a comprehensive rather than partial identification of...
Delivery Method:
Microinjection
Organism or Cell Type:
Ciona intestinalis
Citation Extract:
Imai KS, Hino K, Yagi K, Satoh N, Satou Y. Gene expression profiles of transcription factors and signaling molecules in the ascidian embryo: towards a comprehensive understanding of gene networks. Development. 2004 Aug;131(16):4047-58..

Gene regulatory networks underlying the compartmentalization of the Ciona central nervous system

Authors:
Imai KS, Stolfi A, Levine M, Satou Y
Citation:
Development. 2009 Jan;136(2):285-93. Epub 2008 Dec 15
Epub:
Not Epub
Abstract:
The tripartite organization of the central nervous system (CNS) may be an ancient character of the bilaterians. However, the...
Delivery Method:
Microinjection
Organism or Cell Type:
Ciona intestinalis and Ciona savignyi
Citation Extract:
Imai KS, Stolfi A, Levine M, Satou Y. Gene regulatory networks underlying the compartmentalization of the Ciona central nervous system. Development. 2009 Jan;136(2):285-93. Epub 2008 Dec 15.

Identification and characterization of the zebrafish pharyngeal arch-specific enhancer for the basic helix-loop-helix transcription factor Hand2

Authors:
Iklé JM, Artinger KB, Clouthier DE
Citation:
Dev Biol. 2012 Aug 1;368(1):118-26. doi: 10.1016/j.ydbio.2012.05.003. Epub 2012 May 14.
Epub:
Not Epub
Abstract:
The development of the vertebrate jaw relies on a network of transcription factors that patterns the dorsal-ventral axis of the...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Iklé JM, Artinger KB, Clouthier DE. Identification and characterization of the zebrafish pharyngeal arch-specific enhancer for the basic helix-loop-helix transcription factor Hand2. Dev Biol. 2012 Aug 1;368(1):118-26. doi: 10.1016/j.ydbio.2012.05.003. Epub 2012 May 14..

In vivo Electroporation of Morpholinos into the Regenerating Adult Zebrafish Tail Fin

Authors:
Hyde DR, Godwin AR, Thummel R
Citation:
J Vis Exp. 2012;(61):e3632 DOI: 10.3791/3632
Epub:
Not Epub
Abstract:
<snip – database limit> The zebrafish fin is a relatively simple appendage that is easily manipulated to study multiple...
Delivery Method:
Electroporation
Organism or Cell Type:
zebrafish
Citation Extract:
Hyde DR, Godwin AR, Thummel R. In vivo Electroporation of Morpholinos into the Regenerating Adult Zebrafish Tail Fin. J Vis Exp. 2012;(61):e3632 DOI: 10.3791/3632.

Intraflagellar transport and the sensory outer segment of vertebrate photoreceptors

Authors:
Insinna C, Besharse JC
Citation:
Dev Dyn. 2008 Aug;237(8):1982-92. Review
Epub:
Not Epub
Abstract:
Analysis of the other segments of rod and cone photoreceptors in vertebrates has provided a rich molecular understanding of how...
Organism or Cell Type:
zebrafish
Citation Extract:
Insinna C, Besharse JC. Intraflagellar transport and the sensory outer segment of vertebrate photoreceptors. Dev Dyn. 2008 Aug;237(8):1982-92. Review.

Knockdown of SPARC leads to decreased cell-cell adhesion and lens cataracts during post-gastrula development in Xenopus laevis

Authors:
Huynh MH, Zhu SJ, Kollara A, Brown T, Winklbauer R, Ringuette M
Citation:
Dev Genes Evol. 2011 Mar;220(11-12):315-27. doi: 10.1007/s00427-010-0349-x. Epub 2011 Mar 8.
Epub:
Not Epub
Abstract:
SPARC is a multifunctional matricellular glycoprotein with complex, transient tissue distribution during embryonic development...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Huynh MH, Zhu SJ, Kollara A, Brown T, Winklbauer R, Ringuette M. Knockdown of SPARC leads to decreased cell-cell adhesion and lens cataracts during post-gastrula development in Xenopus laevis. Dev Genes Evol. 2011 Mar;220(11-12):315-27. doi: 10.1007/s00427-010-0349-x. Epub 2011 Mar 8..

MCAK regulates chromosome alignment but is not necessary for preventing aneuploidy in mouse oocyte meiosis I

Authors:
Illingworth C, Pirmadjid N, Serhal P, Howe K, Fitzharris G
Citation:
Development. 2010 Jul;137(13):2133-8. Epub 2010 May 26
Epub:
Not Epub
Abstract:
Errors in chromosome segregation in mammalian oocytes lead to aneuploid eggs that are developmentally compromised. In mitotic...
Delivery Method:
Microinjection
Organism or Cell Type:
mouse oocytes
Citation Extract:
Illingworth C, Pirmadjid N, Serhal P, Howe K, Fitzharris G. MCAK regulates chromosome alignment but is not necessary for preventing aneuploidy in mouse oocyte meiosis I. Development. 2010 Jul;137(13):2133-8. Epub 2010 May 26.

Metalloprotease-Dependent Onset of Blood Circulation in Zebrafish

Authors:
Iida A, Sakaguchi K, Sato K, Sakurai H, Nishimura D, Iwaki A, Takeuchi M, Kobayashi M, Misaki K, Yonemura S, Kawahara A, Sehara-Fujisawa A
Citation:
Curr Biol. 2010 Jun 22;20(12):1110-6. doi: 10.1016/j.cub.2010.04.052. Epub 2010 Jun 3.
Epub:
Not Epub
Abstract:
The primitive blood circulation requires intravascular plasma flow [1]. However, it remains unclear whether the onset of...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Iida A, Sakaguchi K, Sato K, Sakurai H, Nishimura D, Iwaki A, Takeuchi M, Kobayashi M, Misaki K, Yonemura S, Kawahara A, Sehara-Fujisawa A. Metalloprotease-Dependent Onset of Blood Circulation in Zebrafish. Curr Biol. 2010 Jun 22;20(12):1110-6. doi: 10.1016/j.cub.2010.04.052. Epub 2010 Jun 3..

miR-495 is upregulated by E12/E47 in breast cancer stem cells, and promotes oncogenesis and hypoxia resistance via downregulation of E-cadherin and REDD1

Authors:
Hwang-Verslues WW, Chang PH, Wei PC, Yang CY, Huang CK, Kuo WH, Shew JY, Chang KJ, Lee EY, Lee WH
Citation:
Oncogene. 2011 May 26;30(21):2463-74. doi: 10.1038/onc.2010.618. Epub 2011 Jan 24.
Epub:
Not Epub
Abstract:
MicroRNAs (miRNAs) are involved in tumorigenecity by regulating specific oncogenes and tumor suppressor genes, and their roles...
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: HEK 293
Citation Extract:
Hwang-Verslues WW, Chang PH, Wei PC, Yang CY, Huang CK, Kuo WH, Shew JY, Chang KJ, Lee EY, Lee WH. miR-495 is upregulated by E12/E47 in breast cancer stem cells, and promotes oncogenesis and hypoxia resistance via downregulation of E-cadherin and REDD1. Oncogene. 2011 May 26;30(21):2463-74. doi: 10.1038/onc.2010.618. Epub 2011 Jan 24..

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