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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12378 scientific papers returned from the database with the search filters currently being used below.
There are 12378 scientific papers returned from the database with the search filters currently being used below.
Functional analysis of BBS3 A89V that results in non-syndromic retinal degeneration
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Citation:
Hum Mol Genet. 2011 Jan 31. [Epub ahead of print] Epub:
Not Epub Abstract:
Bardet-Biedl Syndrome (BBS) is a syndromic form of retinal degeneration. Recently, homozygosity mapping with a consanguineous... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Pretorius PR, Aldahmesh MA, Alkuraya FS, Sheffield VC, Slusarski DC. Functional analysis of BBS3 A89V that results in non-syndromic retinal degeneration. Hum Mol Genet. 2011 Jan 31. [Epub ahead of print]. |
Germline gain-of-function mutations in RAF1 cause Noonan syndrome
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Citation:
Nat Genet. 2007 Aug;39(8):1013-7. Epub 2007 Jul 1. Epub:
Not Epub Abstract:
Noonan syndrome is characterized by short stature, facial dysmorphia and a wide spectrum of congenital heart defects. Mutations... Organism or Cell Type:
zebrafish Citation Extract: Razzaque MA, Nishizawa T, Komoike Y, Yagi H, Furutani M, Amo R, Kamisago M, Momma K, Katayama H, Nakagawa M, Fujiwara Y, Matsushima M, Mizuno K, Tokuyama M, Hirota H, Muneuchi J, Higashinakagawa T, Matsuoka R. Germline gain-of-function mutations in RAF1 cause Noonan syndrome. Nat Genet. 2007 Aug;39(8):1013-7. Epub 2007 Jul 1.. |
Glucagon is required for early insulin-positive differentiation in the developing mouse pancreas
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Citation:
Diabetes. 2002 Nov;51(11):3229-36 Epub:
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The embryonic pancreas is thought to develop from pluripotent endodermal cells that give rise to endocrine and exocrine cells.... Delivery Method:
oligo bathing Organism or Cell Type:
Mouse embryonic tissue Citation Extract: Prasadan K, Daume E, Preuett B, Spilde T, Bhatia A, Kobayashi H, Hembree M, Manna P, Gittes GK. Glucagon is required for early insulin-positive differentiation in the developing mouse pancreas. Diabetes. 2002 Nov;51(11):3229-36. |
Haem homeostasis is regulated by the conserved and concerted functions of HRG-1 proteins
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Citation:
Nature. 2008 Jun 19;453(7198):1127-31. Epub 2008 Apr 16 Epub:
Not Epub Abstract:
Haems are metalloporphyrins that serve as prosthetic groups for various biological processes including respiration, gas sensing... Organism or Cell Type:
zebrafish Citation Extract: Rajagopal A, Rao AU, Amigo J, Tian M, Upadhyay SK, Hall C, Uhm S, Mathew MK, Fleming MD, Paw BH, Krause M, Hamza I. Haem homeostasis is regulated by the conserved and concerted functions of HRG-1 proteins. Nature. 2008 Jun 19;453(7198):1127-31. Epub 2008 Apr 16. |
Histone H4K20/H3K9 demethylase PHF8 regulates zebrafish brain and craniofacial development
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Citation:
Nature. 2010 Jul 22;466(7305):503-7. Epub 2010 Jul 11 Epub:
Not Epub Abstract:
X-linked mental retardation (XLMR) is a complex human disease that causes intellectual disability. Causal mutations have been... Organism or Cell Type:
zebrafish Citation Extract: Qi HH, Sarkissian M, Hu GQ, Wang Z, Bhattacharjee A, Gordon DB, Gonzales M, Lan F, Ongusaha PP, Huarte M, Yaghi NK, Lim H, Garcia BA, Brizuela L, Zhao K, Roberts TM, Shi Y. Histone H4K20/H3K9 demethylase PHF8 regulates zebrafish brain and craniofacial development. Nature. 2010 Jul 22;466(7305):503-7. Epub 2010 Jul 11. |
Hitting Bacteria at the Heart of the Central Dogma: Sequence-Specific Inhibition
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Citation:
Microb Cell Fact. 2007 Aug 10;6(1):24 [Epub ahead of print] Epub:
Not Epub Abstract:
ABSTRACT: An important objective in developing new drugs is the achievement of high specificity to maximize curing effect and... Organism or Cell Type:
Bacteria (review) Citation Extract: Rasmussen LC, Sperling-Petersen HU, Mortensen KK. Hitting Bacteria at the Heart of the Central Dogma: Sequence-Specific Inhibition. Microb Cell Fact. 2007 Aug 10;6(1):24 [Epub ahead of print] . |
Identification and Functional Analysis of the Vision-Specific BBS3 (ARL6) Long Isoform
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Citation:
PLoS Genet. 2010 Mar 19;6(3):e1000884 Epub:
Not Epub Abstract:
Bardet-Biedl Syndrome (BBS) is a heterogeneous syndromic form of retinal degeneration. We have identified a novel transcript of... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Pretorius PR, Baye LM, Nishimura DY, Searby CC, Bugge K, Yang B, Mullins RF, Stone EM, Sheffield VC, Slusarski DC. Identification and Functional Analysis of the Vision-Specific BBS3 (ARL6) Long Isoform. PLoS Genet. 2010 Mar 19;6(3):e1000884. |
Identification of zebrafish ARNT1 homologs: TCDD toxicity in the developing zebrafish requires ARNT1
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Citation:
2006 Mar;69(3):776-87. Epub 2005 Nov 23. Epub:
Not Epub Abstract:
In order to use the zebrafish as a model to study 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) developmental toxicity, it is... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Prasch AL, Tanguay RL, Mehta V, Heideman W, Peterson RE. Identification of zebrafish ARNT1 homologs: TCDD toxicity in the developing zebrafish requires ARNT1. 2006 Mar;69(3):776-87. Epub 2005 Nov 23.. |
Impaired neural development in a zebrafish model for Lowe syndrome
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Citation:
Hum Mol Genet. 2012 Apr 15;21(8):1744-59. Epub 2011 Dec 30. Epub:
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Lowe syndrome, which is characterized by defects in the central nervous system, eyes and kidneys, is caused by mutation of the... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Ramirez IB, Pietka G, Jones DR, Divecha N, Alia A, Baraban SC, Hurlstone AF, Lowe M. Impaired neural development in a zebrafish model for Lowe syndrome. Hum Mol Genet. 2012 Apr 15;21(8):1744-59. Epub 2011 Dec 30.. |
In the Absence of Sonic Hedgehog, p53 Induces Apoptosis and Inhibits Retinal Cell Proliferation, Cell-Cycle Exit and Differentiation in Zebrafish
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Citation:
PLoS ONE. 2010;5(10): e13549. doi:10.1371/journal.pone.0013549 Epub:
Not Epub Abstract:
Background Sonic hedgehog (Shh) signaling regulates cell proliferation during vertebrate development via induction of cell-... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Prykhozhij SV. In the Absence of Sonic Hedgehog, p53 Induces Apoptosis and Inhibits Retinal Cell Proliferation, Cell-Cycle Exit and Differentiation in Zebrafish. PLoS ONE. 2010;5(10): e13549. doi:10.1371/journal.pone.0013549. |