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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12371 scientific papers returned from the database with the search filters currently being used below.

A novel mitochondrial matrix serine/threonine protein phosphatase regulates the mitochondria permeability transition pore and is essential for cellular survival and development

Authors:
Lu G, Ren S, Korge P, Choi J, Dong Y, Weiss J, Koehler C, Chen JN, Wang Y
Citation:
Genes Dev. 2007 Apr 1;21(7):784-96. Epub 2007 Mar 20
Epub:
Not Epub
Abstract:
Mitochondria play a central role in the regulation of programmed cell death signaling. Here, we report the finding of a...
Organism or Cell Type:
zebrafish
Citation Extract:
Lu G, Ren S, Korge P, Choi J, Dong Y, Weiss J, Koehler C, Chen JN, Wang Y. A novel mitochondrial matrix serine/threonine protein phosphatase regulates the mitochondria permeability transition pore and is essential for cellular survival and development. Genes Dev. 2007 Apr 1;21(7):784-96. Epub 2007 Mar 20.

A TGF-beta control element required for SM alpha -actin expression in vivo also partially mediates GKLF-dependent transcriptional repression.

Authors:
Liu Y, Sinha S, Owens GK.
Citation:
J Biol Chem. 2003 Nov 28; 278(48): 48004-11. Epub 2003 Sep 10.
Epub:
Not Epub
Abstract:
We previously demonstrated that a conserved TGF-beta control element (TCE) within the 5 region of the smooth muscle cell (SMC)...
Delivery Method:
Special Delivery
Organism or Cell Type:
cell culture: rat aortic smooth muscle cells
Citation Extract:
Liu Y, Sinha S, Owens GK.. A TGF-beta control element required for SM alpha -actin expression in vivo also partially mediates GKLF-dependent transcriptional repression.. J Biol Chem. 2003 Nov 28; 278(48): 48004-11. Epub 2003 Sep 10..

A Unique Feature of Toll/IL-1 Receptor Domain-Containing Adaptor Protein Is Partially Responsible for Lipopolysaccharide Insensitivity in Zebrafish with a Highly Conserved Function of Myd88

Authors:
Liu Y, Li M, Fan S, Lin Y, Lin B, Luo F, Zhang C, Chen S, Li Y, Xu A
Citation:
J Immunol. 2010 Aug 11. [Epub ahead of print]
Epub:
Not Epub
Abstract:
MyD88 and Toll/IL-1R domain-containing adaptor protein (TIRAP) are required for the TLR4 response to LPS stimulation in mammals...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Liu Y, Li M, Fan S, Lin Y, Lin B, Luo F, Zhang C, Chen S, Li Y, Xu A. A Unique Feature of Toll/IL-1 Receptor Domain-Containing Adaptor Protein Is Partially Responsible for Lipopolysaccharide Insensitivity in Zebrafish with a Highly Conserved Function of Myd88. J Immunol. 2010 Aug 11. [Epub ahead of print].

A zebrafish model of intrahepatic cholangiocarcinoma by dual expression of hepatitis B virus X and hepatitis C virus core protein in liver

Authors:
Liu W, Chen JR, Hsu CH, Li YH, Chen YM, Lin CY, Huang SJ, Chang ZK, Chen YC, Lin CH, Gong HY, Lin CC, Kawakami K, Wu JL
Citation:
Hepatology. 2012 Dec;56(6):2268-76. doi: 10.1002/hep.25914. PMID: 22729936
Epub:
Not Epub
Abstract:
The mechanisms that mediate the initiation and development of intrahepatic cholangiocarcinoma (ICC) associated with hepatitis B...
Organism or Cell Type:
zebrafish
Citation Extract:
Liu W, Chen JR, Hsu CH, Li YH, Chen YM, Lin CY, Huang SJ, Chang ZK, Chen YC, Lin CH, Gong HY, Lin CC, Kawakami K, Wu JL. A zebrafish model of intrahepatic cholangiocarcinoma by dual expression of hepatitis B virus X and hepatitis C virus core protein in liver. Hepatology. 2012 Dec;56(6):2268-76. doi: 10.1002/hep.25914. PMID: 22729936.

Amino acid variations resulting in functional and nonfunctional zebrafish P2X(1) and P2X (5.1) receptors

Authors:
Low SE, Kuwada JY, Hume RI
Citation:
Purinergic Signal. 2008 Dec;4(4):383-92. Epub 2008 Oct 11
Epub:
Not Epub
Abstract:
Several zebrafish P2X receptors (zP2X(1), zP2X(2), and zP2X(5.1)) have been reported to produce little or no current although...
Organism or Cell Type:
zebrafish
Citation Extract:
Low SE, Kuwada JY, Hume RI. Amino acid variations resulting in functional and nonfunctional zebrafish P2X(1) and P2X (5.1) receptors. Purinergic Signal. 2008 Dec;4(4):383-92. Epub 2008 Oct 11.

Amputation-induced reactive oxygen species are required for successful Xenopus tadpole tail regeneration

Authors:
Love NR, Chen Y, Ishibashi S, Kritsiligkou P, Lea R, Koh Y, Gallop JL, Dorey K, Amaya E
Citation:
Nat Cell Biol. 2013;[Epub ahead of print] doi:/10.1038/ncb2659
Epub:
Not Epub
Abstract:
Understanding the molecular mechanisms that promote successful tissue regeneration is critical for continued advancements in...
Organism or Cell Type:
Xenopus
Citation Extract:
Love NR, Chen Y, Ishibashi S, Kritsiligkou P, Lea R, Koh Y, Gallop JL, Dorey K, Amaya E. Amputation-induced reactive oxygen species are required for successful Xenopus tadpole tail regeneration. Nat Cell Biol. 2013;[Epub ahead of print] doi:/10.1038/ncb2659.

An evolutionary recent neuroepithelial cell adhesion function of huntingtin implicates ADAM10-Ncadherin

Authors:
Lo Sardo V, Zuccato C, Gaudenzi G, Vitali B, Ramos C, Tartari M, Myre MA, Walker JA, Pistocchi A, Conti L, Valenza M, Drung B, Schmidt B, Gusella J, Zeitlin S, Cotelli F, Cattaneo E
Citation:
Nat Neurosci.2012 May;15(5):713-21.
Epub:
Not Epub
Abstract:
The Huntington's disease gene product, huntingtin, is indispensable for neural tube formation, but its role is obscure. We...
Organism or Cell Type:
zebrafish
Citation Extract:
Lo Sardo V, Zuccato C, Gaudenzi G, Vitali B, Ramos C, Tartari M, Myre MA, Walker JA, Pistocchi A, Conti L, Valenza M, Drung B, Schmidt B, Gusella J, Zeitlin S, Cotelli F, Cattaneo E. An evolutionary recent neuroepithelial cell adhesion function of huntingtin implicates ADAM10-Ncadherin. Nat Neurosci.2012 May;15(5):713-21..

Araf kinase antagonizes Nodal-Smad2 activity in mesendoderm development by directly phosphorylating the Smad2 linker region

Authors:
Liu X, Xiong C, Jia S, Zhang Y, Chen Y-G, Wang Q, Meng A
Citation:
Nat Commun. 2013;[Epub ahead of print] doi:10.1038/ncomms2762
Epub:
Not Epub
Abstract:
Smad2/3-mediated transforming growth factor β signalling and the Ras-Raf-Mek-Erk cascade have important roles in stem cell and...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Liu X, Xiong C, Jia S, Zhang Y, Chen Y-G, Wang Q, Meng A. Araf kinase antagonizes Nodal-Smad2 activity in mesendoderm development by directly phosphorylating the Smad2 linker region. Nat Commun. 2013;[Epub ahead of print] doi:10.1038/ncomms2762.

Assessing Teratogenic Changes in a Zebrafish Model of Fetal Alcohol Exposure

Authors:
Loucks E, Ahlgren S
Citation:
J Vis Exp. 2012;61:e3704. DOI: 10.3791/3704
Epub:
Not Epub
Abstract:
Fetal alcohol syndrome (FAS) is a severe manifestation of embryonic exposure to ethanol. It presents with characteristic...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Loucks E, Ahlgren S. Assessing Teratogenic Changes in a Zebrafish Model of Fetal Alcohol Exposure. J Vis Exp. 2012;61:e3704. DOI: 10.3791/3704.

Auger Radiation-Induced, Antisense-Mediated Cytotoxicity of Tumor Cells Using a 3-Component Streptavidin-Delivery Nanoparticle with 111In

Authors:
Liu X, Wang Y, Nakamura K, Kawauchi S, Akalin A, Cheng D, Chen L, Rusckowski M, Hnatowich DJ
Citation:
J Nucl Med. 2009 Apr;50(4):582-90. doi: 10.2967/jnumed.108.056366. Epub 2009 Mar 16
Epub:
Not Epub
Abstract:
When antisense oligomers are intracellular, they migrate to and are retained in the nucleus of tumor cells and therefore may be...
Delivery Method:
Nanoparticle
Organism or Cell Type:
mice
Citation Extract:
Liu X, Wang Y, Nakamura K, Kawauchi S, Akalin A, Cheng D, Chen L, Rusckowski M, Hnatowich DJ. Auger Radiation-Induced, Antisense-Mediated Cytotoxicity of Tumor Cells Using a 3-Component Streptavidin-Delivery Nanoparticle with 111In. J Nucl Med. 2009 Apr;50(4):582-90. doi: 10.2967/jnumed.108.056366. Epub 2009 Mar 16.

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