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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12378 scientific papers returned from the database with the search filters currently being used below.

accordion, a zebrafish behavioral mutant, has a muscle relaxation defect due to a mutation in the ATPase Ca2+ pump SERCA1

Authors:
Hirata H, Saint-Amant L, Waterbury J, Cui W, Zhou W, Li Q, Goldman D, Granato M, Kuwada JY
Citation:
Development. 2004 Nov;131(21):5457-68. Epub 2004 Oct 6
Epub:
Not Epub
Abstract:
When wild-type zebrafish embryos are touched at 24 hours post-fertilization (hpf), they typically perform two rapid alternating...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hirata H, Saint-Amant L, Waterbury J, Cui W, Zhou W, Li Q, Goldman D, Granato M, Kuwada JY. accordion, a zebrafish behavioral mutant, has a muscle relaxation defect due to a mutation in the ATPase Ca2+ pump SERCA1. Development. 2004 Nov;131(21):5457-68. Epub 2004 Oct 6.

Alpha2 macroglobulin-like is essential for liver development in zebrafish

Authors:
Hong SK, Dawid IB
Citation:
PLoS ONE. 2008;3(11):e3736. Epub 2008 Nov 17
Epub:
Not Epub
Abstract:
BACKGROUND: Alpha 2 Macroglobulin family members have been studied extensively with respect to their roles in physiology and...
Organism or Cell Type:
zebrafish
Citation Extract:
Hong SK, Dawid IB. Alpha2 macroglobulin-like is essential for liver development in zebrafish. PLoS ONE. 2008;3(11):e3736. Epub 2008 Nov 17.

An In Vivo Method to Quantify Lymphangiogenesis in Zebrafish

Authors:
Hoffman SJ, Psaltis PJ, Clark KJ, Spoon DB, Chue CD, Ekker SC, Simari RD
Citation:
PLoS ONE. 2012;7(9):e45240. doi:10.1371/journal.pone.0045240
Epub:
Not Epub
Abstract:
Background Lymphangiogenesis is a highly regulated process involved in the pathogenesis of disease. Current in vivo models to...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hoffman SJ, Psaltis PJ, Clark KJ, Spoon DB, Chue CD, Ekker SC, Simari RD. An In Vivo Method to Quantify Lymphangiogenesis in Zebrafish. PLoS ONE. 2012;7(9):e45240. doi:10.1371/journal.pone.0045240.

Analyses of Gene Function in Amphioxus Embryos by Microinjection of mRNAs and Morpholino-oligonucleotides

Authors:
Holland LZ, Onai T
Citation:
Methods Mol Biol. 2011;770:423-38
Epub:
Not Epub
Abstract:
The invertebrate chordate amphioxus (Branchiostoma), which is the most basal living chordate, has become an accepted model for...
Delivery Method:
Microinjection
Organism or Cell Type:
amphioxus
Citation Extract:
Holland LZ, Onai T. Analyses of Gene Function in Amphioxus Embryos by Microinjection of mRNAs and Morpholino-oligonucleotides. Methods Mol Biol. 2011;770:423-38.

Angiomodulin Is a Specific Marker of Vasculature and Regulates Vascular Endothelial Growth Factor-A-Dependent Neoangiogenesis

Authors:
Hooper AT, Shmelkov SV, Gupta S, Milde T, Bambino K, Gillen K, Goetz M, Chavala S, Baljevic M, Murphy AJ, Valenzuela DM, Gale NW, Thurston G, Yancopoulos GD, Vahdat L, Evans T, Rafii S
Citation:
Circ Res. 2009 Jun 18. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Blood vessel formation is controlled by the balance between pro- and antiangiogenic pathways. Although much is known about the...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hooper AT, Shmelkov SV, Gupta S, Milde T, Bambino K, Gillen K, Goetz M, Chavala S, Baljevic M, Murphy AJ, Valenzuela DM, Gale NW, Thurston G, Yancopoulos GD, Vahdat L, Evans T, Rafii S. Angiomodulin Is a Specific Marker of Vasculature and Regulates Vascular Endothelial Growth Factor-A-Dependent Neoangiogenesis. Circ Res. 2009 Jun 18. [Epub ahead of print].

ANKS6 is a central component of a nephronophthisis module linking NEK8 to INVS and NPHP3

Authors:
Hoff S, Halbritter J, Epting D, Frank V, Nguyen TM, van Reeuwijk J, Boehlke C, Schell C, Yasunaga T, Helmstädter M, Mergen M, Filhol E, Boldt K, Horn N, Ueffing M, Otto EA, Eisenberger T, Elting MW, van Wijk JA, Bockenhauer D, Sebire NJ, Rittig S, Vyberg M, Ring T, Pohl M, Pape L, Neuhaus TJ, Elshakhs NA, Koon SJ, Harris PC, Grahammer F, Huber TB, Kuehn EW, Kramer-Zucker A, Bolz HJ, Roepman R, Saunier S, Walz G, Hildebrandt F, Bergmann C, Lienkamp SS
Citation:
Nat Genet. 2013 Jun 23. doi: 10.1038/ng.2681. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Nephronophthisis is an autosomal recessive cystic kidney disease that leads to renal failure in childhood or adolescence. Most...
Organism or Cell Type:
Zebrafish and Xenopus laevis
Citation Extract:
Hoff S, Halbritter J, Epting D, Frank V, Nguyen TM, van Reeuwijk J, Boehlke C, Schell C, Yasunaga T, Helmstädter M, Mergen M, Filhol E, Boldt K, Horn N, Ueffing M, Otto EA, Eisenberger T, Elting MW, van Wijk JA, Bockenhauer D, Sebire NJ, Rittig S, Vyberg M, Ring T, Pohl M, Pape L, Neuhaus TJ, Elshakhs NA, Koon SJ, Harris PC, Grahammer F, Huber TB, Kuehn EW, Kramer-Zucker A, Bolz HJ, Roepman R, Saunier S, Walz G, Hildebrandt F, Bergmann C, Lienkamp SS . ANKS6 is a central component of a nephronophthisis module linking NEK8 to INVS and NPHP3. Nat Genet. 2013 Jun 23. doi: 10.1038/ng.2681. [Epub ahead of print].

Asymmetric endocytosis and remodeling of beta1-integrin adhesions during growth cone chemorepulsion by MAG

Authors:
Hines JH, Abu-Rub M, Henley JR
Citation:
Nat Neurosci. 2010 Jul;13(7):829-37. Epub 2010 May 30
Epub:
Not Epub
Abstract:
Gradients of chemorepellent factors released from myelin may impair axon pathfinding and neuroregeneration after injury. We...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Hines JH, Abu-Rub M, Henley JR. Asymmetric endocytosis and remodeling of beta1-integrin adhesions during growth cone chemorepulsion by MAG. Nat Neurosci. 2010 Jul;13(7):829-37. Epub 2010 May 30.

ATM is down-regulated by N-Myc-regulated microRNA-421

Authors:
Hu H, Du L, Nagabayashi G, Seeger RC, Gatti RA
Citation:
Proc Natl Acad Sci U S A. 2010 Jan 26;107(4):1506-11. doi: 10.1073/pnas.0907763107. Epub 2010 Jan 4.
Epub:
Not Epub
Abstract:
Ataxia-telangiectasia mutated (ATM) is a high molecular weight protein serine/threonine kinase that plays a central role in the...
Organism or Cell Type:
cellculture: neuroblastoma cells, HeLa
Citation Extract:
Hu H, Du L, Nagabayashi G, Seeger RC, Gatti RA. ATM is down-regulated by N-Myc-regulated microRNA-421. Proc Natl Acad Sci U S A. 2010 Jan 26;107(4):1506-11. doi: 10.1073/pnas.0907763107. Epub 2010 Jan 4..

BIN1 is Reduced and Cav1.2 Trafficking is Impaired in Human Failing Cardiomyocytes

Authors:
Hong TT, Smyth JW, Chu KY, Vogan JM, Fong TS, Jensen BC, Fang K, Halushka MK, Russell SD, Colecraft H, Hoopes CW, Ocorr K, Chi NC, Shaw RM
Citation:
Heart Rhythm. 2011 Dec 1. [Epub ahead of print]
Epub:
Not Epub
Abstract:
BACKGROUND: Heart failure is a growing epidemic and a typical aspect of heart failure pathophysiology is altered calcium...
Organism or Cell Type:
zebrafish
Citation Extract:
Hong TT, Smyth JW, Chu KY, Vogan JM, Fong TS, Jensen BC, Fang K, Halushka MK, Russell SD, Colecraft H, Hoopes CW, Ocorr K, Chi NC, Shaw RM. BIN1 is Reduced and Cav1.2 Trafficking is Impaired in Human Failing Cardiomyocytes. Heart Rhythm. 2011 Dec 1. [Epub ahead of print].

Biosynthesis of Wdr16, a marker protein for kinocilia-bearing cells, starts at the time of kinocilia formation in rat, and wdr16 gene knockdown causes hydrocephalus in zebrafish

Authors:
Hirschner W, Pogoda HM, Kramer C, Thiess U, Hamprecht B, Wiesmuller KH, Lautner M, Verleysdonk S
Citation:
J Neurochem. 2007 Apr;101(1):274-88
Epub:
Not Epub
Abstract:
The rat ortholog of the WD40 repeat protein Wdr16 is abundantly expressed in testis and cultured ependymal cells. Low levels...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hirschner W, Pogoda HM, Kramer C, Thiess U, Hamprecht B, Wiesmuller KH, Lautner M, Verleysdonk S. Biosynthesis of Wdr16, a marker protein for kinocilia-bearing cells, starts at the time of kinocilia formation in rat, and wdr16 gene knockdown causes hydrocephalus in zebrafish. J Neurochem. 2007 Apr;101(1):274-88.

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