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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

Matrix metalloproteinase 9 modulates collagen matrices and wound repair

Authors:
LeBert DC, Squirrell JM, Rindy J, Broadbridge E, Lui Y, Zakrzewska A, Eliceiri KW, Meijer AH, Huttenlocher A
Citation:
Development. 2015 May 26. pii: dev.121160. [Epub ahead of print]
Epub:
Yes
Abstract:
Acute and chronic injuries are characterized by leukocyte infiltration into tissues. Although matrix metalloproteinase 9 (Mmp9...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
LeBert DC, Squirrell JM, Rindy J, Broadbridge E, Lui Y, Zakrzewska A, Eliceiri KW, Meijer AH, Huttenlocher A. Matrix metalloproteinase 9 modulates collagen matrices and wound repair. Development. 2015 May 26. pii: dev.121160. [Epub ahead of print].

Combination Antisense Treatment for Destructive Exon Skipping of Myostatin and Open Reading Frame Rescue of Dystrophin in Neonatal mdx Mice

Authors:
Lu-Nguyen NB, Jarmin SA, Saleh AF, Popplewell L, Gait MJ, Dickson G
Citation:
Mol Ther. 2015;[Epub ahead of print] doi:10.1038/mt.2015.88
Epub:
Yes
Abstract:
The fatal X-linked Duchenne muscular dystrophy (DMD), characterized by progressive muscle wasting and muscle weakness, is...
Delivery Method:
peptide-linked
Organism or Cell Type:
mice, mdx
Citation Extract:
Lu-Nguyen NB, Jarmin SA, Saleh AF, Popplewell L, Gait MJ, Dickson G. Combination Antisense Treatment for Destructive Exon Skipping of Myostatin and Open Reading Frame Rescue of Dystrophin in Neonatal mdx Mice. Mol Ther. 2015;[Epub ahead of print] doi:10.1038/mt.2015.88.

Planar polarization of Vangl2 in the vertebrate neural plate is controlled by Wnt and Myosin II signaling

Authors:
Ossipova O, Kim K, Sokol SY
Citation:
Biol Open. 2015 Apr 24. pii: bio.011676. doi: 10.1242/bio.201511676. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The vertebrate neural tube forms as a result of complex morphogenetic movements, which require the functions of several core...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Ossipova O, Kim K, Sokol SY. Planar polarization of Vangl2 in the vertebrate neural plate is controlled by Wnt and Myosin II signaling. Biol Open. 2015 Apr 24. pii: bio.011676. doi: 10.1242/bio.201511676. [Epub ahead of print].

Mitotic cell rounding and epithelial thinning regulate lumen growth and shape

Authors:
Hoijman E, Rubbini D, Colombelli J, Alsina B
Citation:
Nat Comm. 2015;6:7355. doi:10.1038/ncomms8355
Epub:
Not Epub
Abstract:
Many organ functions rely on epithelial cavities with particular shapes. Morphogenetic anomalies in these cavities lead to...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hoijman E, Rubbini D, Colombelli J, Alsina B. Mitotic cell rounding and epithelial thinning regulate lumen growth and shape. Nat Comm. 2015;6:7355. doi:10.1038/ncomms8355.

Yes-Associated Protein (Yap) Is Necessary for Ciliogenesis and Morphogenesis during Pronephros Development in Zebrafish (Danio Rerio)

Authors:
He L, Xu W, Jing Y, Wu M, Song S, Cao Y, Mei C
Citation:
Int J Biol Sci. 2015;11(8):935-947. doi:10.7150/ijbs.11346
Epub:
Not Epub
Abstract:
The Hippo signaling pathway and its transcriptional co-activator Yap are known as essential regulators for cell proliferation...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
He L, Xu W, Jing Y, Wu M, Song S, Cao Y, Mei C. Yes-Associated Protein (Yap) Is Necessary for Ciliogenesis and Morphogenesis during Pronephros Development in Zebrafish (Danio Rerio). Int J Biol Sci. 2015;11(8):935-947. doi:10.7150/ijbs.11346.

Inhibition of hepatitis E virus replication by peptide-conjugated morpholino oligomers

Authors:
Nan Y, Ma Z, Kannan H, Stein DA, Iversen PI, Meng XJ, Zhang YJ
Citation:
Antiviral Res. 2015 Aug;120:134-9. doi: 10.1016/j.antiviral.2015.06.006. Epub 2015 Jun 15. PMID: 26086884; PMCID: PMC4502978
Epub:
Yes
Abstract:
Hepatitis E virus (HEV) infection is a cause of hepatitis in humans worldwide and has been associated with a mortality rate of...
Delivery Method:
peptide-linked
Organism or Cell Type:
cell culture: liver cells
Citation Extract:
Nan Y, Ma Z, Kannan H, Stein DA, Iversen PI, Meng XJ, Zhang YJ. Inhibition of hepatitis E virus replication by peptide-conjugated morpholino oligomers. Antiviral Res. 2015 Aug;120:134-9. doi: 10.1016/j.antiviral.2015.06.006. Epub 2015 Jun 15. PMID: 26086884; PMCID: PMC4502978.

Super-Resolution Imaging and Quantitative Analysis of Membrane Protein/Lipid Raft Clustering Mediated by Cell Surface Self-Assembly of Hybrid Nanoconjugates

Authors:
Hartley JM, Chu T-W, Peterson EM, Zhang R, Yang J, Harris J, Kopecek J
Citation:
ChemBioChem. 2015 Aug 17;16(12):1725-9. doi: 10.1002/cbic.201500278. Epub 2015 Jul 2.
Epub:
Yes
Abstract:
Super-resolution imaging was used to quantify organizational changes in the plasma membrane after treatment with hybrid...
Organism or Cell Type:
cell culture: Human Burkitt’s B-cell non-Hodgkin’s lymphoma Raji cell line
Citation Extract:
Hartley JM, Chu T-W, Peterson EM, Zhang R, Yang J, Harris J, Kopecek J. Super-Resolution Imaging and Quantitative Analysis of Membrane Protein/Lipid Raft Clustering Mediated by Cell Surface Self-Assembly of Hybrid Nanoconjugates. ChemBioChem. 2015 Aug 17;16(12):1725-9. doi: 10.1002/cbic.201500278. Epub 2015 Jul 2..

Mecp2 regulates neural cell differentiation by suppressing the Id1 to Her2 axis in zebrafish

Authors:
Gao H, Bu Y, Wu Q, Wang X, Chang N, Lei L, Chen S, Liu D, Zhu S, Hu K, Jing-Wei Xiong J-W
Citation:
J Cell Sci. 2015;128:2340-2350. doi:10.1242/jcs.167874
Epub:
Not Epub
Abstract:
Rett syndrome (RTT) is a progressive neurological disorder caused by mutations in the X-linked protein methyl-CpG-binding...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Gao H, Bu Y, Wu Q, Wang X, Chang N, Lei L, Chen S, Liu D, Zhu S, Hu K, Jing-Wei Xiong J-W. Mecp2 regulates neural cell differentiation by suppressing the Id1 to Her2 axis in zebrafish. J Cell Sci. 2015;128:2340-2350. doi:10.1242/jcs.167874.

Crystal structure and potential physiological role of zebra fish thioesterase superfamily member 2 (fTHEM2)

Authors:
Yu S, Li H, Gao F, Zhou Y
Citation:
Biochem Biophys Res Commun. 2015 Jun 9. pii: S0006-291X(15)30092-9. doi: 10.1016/j.bbrc.2015.06.034. [Epub ahead of print]
Epub:
Yes
Abstract:
Thioesterase superfamily member 2 (THEM2) is an essential protein for mammalian cell proliferation. It belongs to the hotdog-...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Yu S, Li H, Gao F, Zhou Y. Crystal structure and potential physiological role of zebra fish thioesterase superfamily member 2 (fTHEM2). Biochem Biophys Res Commun. 2015 Jun 9. pii: S0006-291X(15)30092-9. doi: 10.1016/j.bbrc.2015.06.034. [Epub ahead of print].

Inversion of Sonic hedgehog action on its canonical pathway by electrical activity

Authors:
Belgacem YH, Borodinsky LN
Citation:
Proc Natl Acad Sci U S A. 2015 Mar 31;112(13):4140-5. doi: 10.1073/pnas.1419690112. Epub 2015 Mar 17
Epub:
Not Epub
Abstract:
Sonic hedgehog (Shh) is a morphogenic protein that operates through the Gli transcription factor-dependent canonical pathway to...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Belgacem YH, Borodinsky LN. Inversion of Sonic hedgehog action on its canonical pathway by electrical activity. Proc Natl Acad Sci U S A. 2015 Mar 31;112(13):4140-5. doi: 10.1073/pnas.1419690112. Epub 2015 Mar 17.

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