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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12371 scientific papers returned from the database with the search filters currently being used below.

Chronic administration of the methylxanthine propentofylline impairs reinstatement to cocaine by a GLT-1-dependent mechanism

Authors:
Reissner KJ, Brown RM, Spencer S, Tran PK, Thomas CA, Kalivas PW
Citation:
Neuropsychopharmacology. 2014 Jan;39(2):499-506. doi: 10.1038/npp.2013.223. Epub 2013 Aug 29
Epub:
Not Epub
Abstract:
In recent years, interactions between neurons and glia have been evaluated as mediators of neuropsychiatric diseases, including...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
rat
Citation Extract:
Reissner KJ, Brown RM, Spencer S, Tran PK, Thomas CA, Kalivas PW. Chronic administration of the methylxanthine propentofylline impairs reinstatement to cocaine by a GLT-1-dependent mechanism. Neuropsychopharmacology. 2014 Jan;39(2):499-506. doi: 10.1038/npp.2013.223. Epub 2013 Aug 29.

Comparison between two labeled agents in mice using a coinjection-ratio approach in contrast to a conventional group approach

Authors:
Dou S, Wang Y, Barton B, Chen L, Rusckowski M, Shultz LD, Greiner DL, Liu G
Citation:
Nucl Med Biol. 2014 Jan;41(1):127-31. doi: 10.1016/j.nucmedbio.2013.10.001. Epub 2013 Oct 9
Epub:
Not Epub
Abstract:
INTRODUCTION: The differences between two agents often need to be accurately defined in vivo. Usually they are injected...
Organism or Cell Type:
mice
Citation Extract:
Dou S, Wang Y, Barton B, Chen L, Rusckowski M, Shultz LD, Greiner DL, Liu G. Comparison between two labeled agents in mice using a coinjection-ratio approach in contrast to a conventional group approach. Nucl Med Biol. 2014 Jan;41(1):127-31. doi: 10.1016/j.nucmedbio.2013.10.001. Epub 2013 Oct 9.

In vivo gene silencing following non-invasive siRNA delivery into the skin using a novel topical formulation

Authors:
Hegde V, Hickerson RP, Nainamalai S, Campbell PA, Smith FJ, McLean WH, Pedrioli DM
Citation:
J Control Release. 2014 Dec 28;196:355-62. doi: 10.1016/j.jconrel.2014.10.022. Epub 2014 Oct 30
Epub:
Not Epub
Abstract:
Therapeutics based on short interfering RNAs (siRNAs), which act by inhibiting the expression of target transcripts, represent...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
mice
Citation Extract:
Hegde V, Hickerson RP, Nainamalai S, Campbell PA, Smith FJ, McLean WH, Pedrioli DM. In vivo gene silencing following non-invasive siRNA delivery into the skin using a novel topical formulation. J Control Release. 2014 Dec 28;196:355-62. doi: 10.1016/j.jconrel.2014.10.022. Epub 2014 Oct 30.

Long-chain Acyl-CoA synthetase 4A regulates Smad activity and dorsoventral patterning in the zebrafish embryo

Authors:
Miyares RL, Stein C, Renisch B, Anderson JL, Hammerschmidt M, Farber SA
Citation:
Dev Cell. 2013 Dec 23;27(6):635-47. doi: 10.1016/j.devcel.2013.11.011. Epub 2013 Dec 12
Epub:
Not Epub
Abstract:
Long-chain polyunsaturated fatty acids (LC-PUFA) and their metabolites are critical players in cell biology and embryonic...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Miyares RL, Stein C, Renisch B, Anderson JL, Hammerschmidt M, Farber SA. Long-chain Acyl-CoA synthetase 4A regulates Smad activity and dorsoventral patterning in the zebrafish embryo. Dev Cell. 2013 Dec 23;27(6):635-47. doi: 10.1016/j.devcel.2013.11.011. Epub 2013 Dec 12.

Several cis-regulatory elements control mRNA stability, translation efficiency, and expression pattern of Prrxl1 (paired related homeobox protein-like 1)

Authors:
Regadas I, Matos MR, Monteiro FA, Gómez-Skarmeta JL, Lima D, Bessa J, Casares F, Reguenga C
Citation:
J Biol Chem. 2013 Dec 20;288(51):36285-301. doi: 10.1074/jbc.M113.491993. Epub 2013 Nov 8
Epub:
Not Epub
Abstract:
The homeodomain transcription factor Prrxl1/DRG11 has emerged as a crucial molecule in the establishment of the pain circuitry...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Regadas I, Matos MR, Monteiro FA, Gómez-Skarmeta JL, Lima D, Bessa J, Casares F, Reguenga C. Several cis-regulatory elements control mRNA stability, translation efficiency, and expression pattern of Prrxl1 (paired related homeobox protein-like 1). J Biol Chem. 2013 Dec 20;288(51):36285-301. doi: 10.1074/jbc.M113.491993. Epub 2013 Nov 8.

IQGAP1 protein regulates nuclear localization of β-catenin via importin-β5 protein in Wnt signaling

Authors:
Goto T, Sato A, Adachi S, Iemura S, Natsume T, Shibuya H
Citation:
J Biol Chem. 2013 Dec 20;288(51):36351-60. doi: 10.1074/jbc.M113.520528. Epub 2013 Nov 6
Epub:
Not Epub
Abstract:
In the canonical Wnt signaling pathway, the translocation of β-catenin is important for the activation of target genes in the...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Goto T, Sato A, Adachi S, Iemura S, Natsume T, Shibuya H. IQGAP1 protein regulates nuclear localization of β-catenin via importin-β5 protein in Wnt signaling. J Biol Chem. 2013 Dec 20;288(51):36351-60. doi: 10.1074/jbc.M113.520528. Epub 2013 Nov 6.

A mutation in cnot8, component of the Ccr4-not complex regulating transcript stability, affects expression levels of developmental regulators and reveals a role of Fgf3 in development of caudal hypothalamic dopaminergic neurons

Authors:
Koch P, Löhr HB, Driever W
Citation:
PLoS One. 2014 Dec 5;9(12):e113829. doi: 10.1371/journal.pone.0113829. eCollection 2014
Epub:
Not Epub
Abstract:
While regulation of the activity of developmental control genes at the transcriptional level as well as by specific miRNA-based...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Koch P, Löhr HB, Driever W. A mutation in cnot8, component of the Ccr4-not complex regulating transcript stability, affects expression levels of developmental regulators and reveals a role of Fgf3 in development of caudal hypothalamic dopaminergic neurons. PLoS One. 2014 Dec 5;9(12):e113829. doi: 10.1371/journal.pone.0113829. eCollection 2014.

Characterization of zebrafish Abcc4 as an efflux transporter of organochlorine pesticides

Authors:
Lu X, Long Y, Lin L, Sun R, Zhong S, Cui Z
Citation:
PLoS One. 2014 Dec 5;9(12):e111664. doi: 10.1371/journal.pone.0111664. eCollection 2014
Epub:
Not Epub
Abstract:
DDT and lindane are highly toxic organochlorine pesticides and posing adverse effects on the environment and public health due...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lu X, Long Y, Lin L, Sun R, Zhong S, Cui Z. Characterization of zebrafish Abcc4 as an efflux transporter of organochlorine pesticides. PLoS One. 2014 Dec 5;9(12):e111664. doi: 10.1371/journal.pone.0111664. eCollection 2014.

Mechanistic target of rapamycin complex 1 signaling regulates cell proliferation, cell survival, and differentiation in regenerating zebrafish fins

Authors:
Hirose K, Shiomi T, Hozumi S, Kikuchi Y
Citation:
BMC Dev Biol. 2014 Dec 6;14(1):42. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Background: The mechanistic target of rapamycin complex1 (mTORC1) signaling pathway has been implicated in functions of...
Delivery Method:
electroporation
Organism or Cell Type:
zebrafish
Citation Extract:
Hirose K, Shiomi T, Hozumi S, Kikuchi Y. Mechanistic target of rapamycin complex 1 signaling regulates cell proliferation, cell survival, and differentiation in regenerating zebrafish fins. BMC Dev Biol. 2014 Dec 6;14(1):42. [Epub ahead of print].

Analysis of skeletal muscle defects in larval zebrafish by birefringence and touch-evoke escape response assays

Authors:
Smith LL, Beggs AH, Gupta VA
Citation:
J Vis Exp. 2013 Dec 13;(82):e50925. doi: 10.3791/50925
Epub:
Not Epub
Abstract:
Zebrafish (Danio rerio) have become a particularly effective tool for modeling human diseases affecting skeletal muscle,...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Smith LL, Beggs AH, Gupta VA. Analysis of skeletal muscle defects in larval zebrafish by birefringence and touch-evoke escape response assays. J Vis Exp. 2013 Dec 13;(82):e50925. doi: 10.3791/50925.

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