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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12371 scientific papers returned from the database with the search filters currently being used below.

Restricted expression of cdc25a in the tailbud is essential for formation of the zebrafish posterior body

Authors:
Bouldin CM, Snelson CD, Farr GH 3rd, Kimelman D
Citation:
Genes Dev. 2014 Feb 15;28(4):384-95. doi: 10.1101/gad.233577.113. Epub 2014 Jan 29
Epub:
Not Epub
Abstract:
The vertebrate body forms from a multipotent stem cell-like progenitor population that progressively contributes newly...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bouldin CM, Snelson CD, Farr GH 3rd, Kimelman D. Restricted expression of cdc25a in the tailbud is essential for formation of the zebrafish posterior body. Genes Dev. 2014 Feb 15;28(4):384-95. doi: 10.1101/gad.233577.113. Epub 2014 Jan 29.

Serum and glucocorticoid-regulated kinase 1 regulates neutrophil clearance during inflammation resolution

Authors:
Burgon J, Robertson AL, Sadiku P, Wang X, Hooper-Greenhill E, Prince LR, Walker P, Hoggett EE, Ward JR, Farrow SN, Zuercher WJ, Jeffrey P, Savage CO, Ingham PW, Hurlstone AF, Whyte MK, Renshaw SA
Citation:
J Immunol. 2014 Feb 15;192(4):1796-805. doi: 10.4049/jimmunol.1300087. Epub 2014 Jan 15
Epub:
Not Epub
Abstract:
The inflammatory response is integral to maintaining health by functioning to resist microbial infection and repair tissue...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Burgon J, Robertson AL, Sadiku P, Wang X, Hooper-Greenhill E, Prince LR, Walker P, Hoggett EE, Ward JR, Farrow SN, Zuercher WJ, Jeffrey P, Savage CO, Ingham PW, Hurlstone AF, Whyte MK, Renshaw SA. Serum and glucocorticoid-regulated kinase 1 regulates neutrophil clearance during inflammation resolution. J Immunol. 2014 Feb 15;192(4):1796-805. doi: 10.4049/jimmunol.1300087. Epub 2014 Jan 15.

Retinal regeneration in adult zebrafish requires regulation of TGFβ signaling

Authors:
Lenkowski JR, Qin Z, Sifuentes CJ, Thummel R, Soto CM, Moens CB, Raymond PA
Citation:
Glia. 2013 Oct;61(10):1687-97. doi: 10.1002/glia.22549. Epub 2013 Aug 5
Epub:
Not Epub
Abstract:
Müller glia are the resident radial glia in the vertebrate retina. The response of mammalian Müller glia to retinal damage...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lenkowski JR, Qin Z, Sifuentes CJ, Thummel R, Soto CM, Moens CB, Raymond PA. Retinal regeneration in adult zebrafish requires regulation of TGFβ signaling. Glia. 2013 Oct;61(10):1687-97. doi: 10.1002/glia.22549. Epub 2013 Aug 5.

Mutations in STX1B, encoding a presynaptic protein, cause fever-associated epilepsy syndromes

Authors:
Schubert J, Siekierska A, Langlois M, May P, Huneau C, Becker F, Muhle H, Suls A, Lemke JR, de Kovel CGF, Thiele H, Konrad K, Kawalia A, Toliat MR, Sander T, Rüschendorf F, Caliebe A, Nagel I, Kohl B, Kecskés A, Jacmin M, Hardies K, Weckhuysen S, Riesch E, Dorn T, Brilstra EH, Baulac S, Møller RS, Hjalgrim H, Koeleman BPC, EuroEPINOMICS RES Consortium, Jurkat-Rott K, Lehman-Horn F, Roach JC, Glusman G, Hood L, Galas DJ, Martin B, de Witte PAM, Biskup S, De Jonghe P, Helbig I, Balling R, Nürnberg P, Crawford AD, Esguerra CV, Weber YG, Lerche H
Citation:
Nat Genet. 2014;[Epub ahead pf print] doi:10.1038/ng.3130
Epub:
Yes
Abstract:
Febrile seizures affect 2-4% of all children and have a strong genetic component. Recurrent mutations in three main genes (...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Schubert J, Siekierska A, Langlois M, May P, Huneau C, Becker F, Muhle H, Suls A, Lemke JR, de Kovel CGF, Thiele H, Konrad K, Kawalia A, Toliat MR, Sander T, Rüschendorf F, Caliebe A, Nagel I, Kohl B, Kecskés A, Jacmin M, Hardies K, Weckhuysen S, Riesch E, Dorn T, Brilstra EH, Baulac S, Møller RS, Hjalgrim H, Koeleman BPC, EuroEPINOMICS RES Consortium, Jurkat-Rott K, Lehman-Horn F, Roach JC, Glusman G, Hood L, Galas DJ, Martin B, de Witte PAM, Biskup S, De Jonghe P, Helbig I, Balling R, Nürnberg P, Crawford AD, Esguerra CV, Weber YG, Lerche H. Mutations in STX1B, encoding a presynaptic protein, cause fever-associated epilepsy syndromes. Nat Genet. 2014;[Epub ahead pf print] doi:10.1038/ng.3130.

Bicaudal-C is required for the formation of anterior neurogenic ectoderm in the sea urchin embryo

Authors:
Yaguchi S, Yaguchi J, Inaba K
Citation:
Sci Rep. 2014 Oct 31;4:6852. doi: 10.1038/srep06852
Epub:
Not Epub
Abstract:
bicaudal-C (bicC) mRNA encodes a protein containing RNA-binding domains that is reported to be maternally present with...
Delivery Method:
microinjection
Organism or Cell Type:
Hemicentrotus pulcherrimus (sea urchin)
Citation Extract:
Yaguchi S, Yaguchi J, Inaba K. Bicaudal-C is required for the formation of anterior neurogenic ectoderm in the sea urchin embryo. Sci Rep. 2014 Oct 31;4:6852. doi: 10.1038/srep06852.

Homozygous splice mutation in CWF19L1 in a Turkish family with recessive ataxia syndrome

Authors:
Burns R, Majczenko K, Xu J, Peng W, Yapici Z, Dowling JJ, Li JZ, Burmeister M
Citation:
Neurology. 2014 Oct 31. pii: 10.1212/WNL.0000000000001053. [Epub ahead of print]
Epub:
Yes
Abstract:
OBJECTIVE: To elucidate the genetic cause of a rare recessive ataxia presented by 2 siblings from a consanguineous Turkish...
Organism or Cell Type:
zebrafish
Citation Extract:
Burns R, Majczenko K, Xu J, Peng W, Yapici Z, Dowling JJ, Li JZ, Burmeister M. Homozygous splice mutation in CWF19L1 in a Turkish family with recessive ataxia syndrome. Neurology. 2014 Oct 31. pii: 10.1212/WNL.0000000000001053. [Epub ahead of print].

A Spaetzle-like role for nerve growth factor β in vertebrate immunity to Staphylococcus aureus

Authors:
Hepburn L, Prajsnar TK, Klapholz C, Moreno P, Loynes CA, Ogryzko NV, Brown K, Schiebler M, Hegyi K, Antrobus R, Hammond KL, Connolly J, Ochoa B, Bryant C, Otto M, Surewaard B, Seneviratne SL, Grogono DM, Cachat J, Ny T, Kaser A, Török ME, Peacock SJ, Holden M, Blundell T, Wang L, Ligoxygakis P, Minichiello L, Woods CG, Foster SJ, Renshaw SA, Floto RA
Citation:
Science. 2014;346(6209):641-6. doi:10.1126/science.1258705
Epub:
Not Epub
Abstract:
Many key components of innate immunity to infection are shared between Drosophila and humans. However, the fly Toll ligand...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hepburn L, Prajsnar TK, Klapholz C, Moreno P, Loynes CA, Ogryzko NV, Brown K, Schiebler M, Hegyi K, Antrobus R, Hammond KL, Connolly J, Ochoa B, Bryant C, Otto M, Surewaard B, Seneviratne SL, Grogono DM, Cachat J, Ny T, Kaser A, Török ME, Peacock SJ, Holden M, Blundell T, Wang L, Ligoxygakis P, Minichiello L, Woods CG, Foster SJ, Renshaw SA, Floto RA. A Spaetzle-like role for nerve growth factor β in vertebrate immunity to Staphylococcus aureus. Science. 2014;346(6209):641-6. doi:10.1126/science.1258705.

A Recurrent CEP120 Mutation in Jeune Asphyxiating Thoracic Dystrophy Expands the Role of Centriolar Proteins in Skeletal Ciliopathies

Authors:
Shaheen R, Schmidts M, Faqeih E, Hashem A, Lausch E, Holder I, Superti-Furga A, UK10 K consortium, Mitchison HM, Almoisheer A, Alamro R, Alshiddi T, Alzahrani F, Beales PL, Alkuraya FS
Citation:
Hum Mol Genet. 2014;[Epub ahead of print] doi:10.1093/hmg/ddu555
Epub:
Yes
Abstract:
Jeune asphyxiating thoracic dystrophy (JATD) is a skeletal dysplasia characterized by a small thoracic cage and a range of...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Shaheen R, Schmidts M, Faqeih E, Hashem A, Lausch E, Holder I, Superti-Furga A, UK10 K consortium, Mitchison HM, Almoisheer A, Alamro R, Alshiddi T, Alzahrani F, Beales PL, Alkuraya FS. A Recurrent CEP120 Mutation in Jeune Asphyxiating Thoracic Dystrophy Expands the Role of Centriolar Proteins in Skeletal Ciliopathies. Hum Mol Genet. 2014;[Epub ahead of print] doi:10.1093/hmg/ddu555 .

Fgf16 Is Required for Specification of GABAergic Neurons and Oligodendrocytes in the Zebrafish Forebrain

Authors:
Miyake A, Chitose T, Kamei E, Murakami A, Nakayama Y, Konishi M, Itoh N
Citation:
PLoS One. 2014 Oct 30;9(10):e110836. doi: 10.1371/journal.pone.0110836. eCollection 2014
Epub:
Not Epub
Abstract:
Fibroblast growth factor (Fgf) signaling plays crucial roles in various developmental processes including those in the brain....
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Miyake A, Chitose T, Kamei E, Murakami A, Nakayama Y, Konishi M, Itoh N. Fgf16 Is Required for Specification of GABAergic Neurons and Oligodendrocytes in the Zebrafish Forebrain. PLoS One. 2014 Oct 30;9(10):e110836. doi: 10.1371/journal.pone.0110836. eCollection 2014.

Differentiation between temporary and real non-clearability of biotinylated IgG antibody by avidin in mice

Authors:
Dou S, Virostko J, Rusckowski M, Greiner DL, Powers AC, Liu G
Citation:
Front Pharmacol. 2014 Jul 24;5:172. doi: 10.3389/fphar.2014.00172. eCollection 2014
Epub:
Not Epub
Abstract:
Although an increasing number of antibody conjugates are being used in the clinic, there remain many unmet needs in antibody...
Delivery Method:
pretargeting
Organism or Cell Type:
mice
Citation Extract:
Dou S, Virostko J, Rusckowski M, Greiner DL, Powers AC, Liu G. Differentiation between temporary and real non-clearability of biotinylated IgG antibody by avidin in mice. Front Pharmacol. 2014 Jul 24;5:172. doi: 10.3389/fphar.2014.00172. eCollection 2014.

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