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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12371 scientific papers returned from the database with the search filters currently being used below.

Nonsense-mediated mRNA decay effectors are essential for zebrafish embryonic development and survival

Authors:
Wittkopp N, Huntzinger E, Weiler C, Saulière J, Schmidt S, Sonawane M, Izaurralde E
Citation:
Mol Cell Biol. 2009 Jul;29(13):3517-28. Epub 2009 May 4
Epub:
Not Epub
Abstract:
The nonsense-mediated mRNA decay (NMD) pathway promotes rapid degradation of mRNAs containing premature translation termination...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wittkopp N, Huntzinger E, Weiler C, Saulière J, Schmidt S, Sonawane M, Izaurralde E. Nonsense-mediated mRNA decay effectors are essential for zebrafish embryonic development and survival. Mol Cell Biol. 2009 Jul;29(13):3517-28. Epub 2009 May 4.

Notch signaling, wt1 and foxc2 are key regulators of the podocyte gene regulatory network in Xenopus

Authors:
White JT, Zhang B, Cerqueira DM, Tran U, Wessely O
Citation:
Development. 2010 Apr 28. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Podocytes are highly specialized cells in the vertebrate kidney. They participate in the formation of the size-exclusion...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
White JT, Zhang B, Cerqueira DM, Tran U, Wessely O. Notch signaling, wt1 and foxc2 are key regulators of the podocyte gene regulatory network in Xenopus. Development. 2010 Apr 28. [Epub ahead of print].

Novel compounds for the treatment of Duchenne muscular dystrophy: emerging therapeutic agents

Authors:
Wilton SD, Fletcher S
Citation:
The Application of Clinical Genetics. 2011 Mar 11;2011(4):29-44
Epub:
Not Epub
Abstract:
The identification of dystrophin and the causative role of mutations in this gene in Duchenne and Becker muscular dystrophies (...
Citation Extract:
Wilton SD, Fletcher S. Novel compounds for the treatment of Duchenne muscular dystrophy: emerging therapeutic agents. The Application of Clinical Genetics. 2011 Mar 11;2011(4):29-44.

Nuclear beta-catenin-dependent Wnt8 signaling in vegetal cells of the early sea urchin embryo regulates gastrulation and differentiation of endoderm and mesodermal cell lineages

Authors:
Wikramanayake AH, Peterson R, Chen J, Huang L, Bince JM, McClay DR, Klein WH
Citation:
Genesis. 2004 Jul;39(3):194-205
Epub:
Not Epub
Abstract:
The entry of beta-catenin into vegetal cell nuclei beginning at the 16-cell stage is one of the earliest known molecular...
Delivery Method:
Microinjection
Organism or Cell Type:
Sea urchin, Strongylocentrotus purpuratus
Citation Extract:
Wikramanayake AH, Peterson R, Chen J, Huang L, Bince JM, McClay DR, Klein WH. Nuclear beta-catenin-dependent Wnt8 signaling in vegetal cells of the early sea urchin embryo regulates gastrulation and differentiation of endoderm and mesodermal cell lineages. Genesis. 2004 Jul;39(3):194-205.

O-GlcNAc modifications regulate cell survival and epiboly during zebrafish development

Authors:
Webster DM, Teo CF, Sun Y, Wloga D, Gay S, Klonowski KD, Wells L, Dougan ST
Citation:
BMC Dev Biol. 2009 Apr 21;9(1):28. [Epub ahead of print]
Epub:
Not Epub
Abstract:
ABSTRACT: BACKGROUND: The post-translational addition of the monosaccharide O-linked beta-N-acetylglucosamine (O-GlcNAc)...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Webster DM, Teo CF, Sun Y, Wloga D, Gay S, Klonowski KD, Wells L, Dougan ST. O-GlcNAc modifications regulate cell survival and epiboly during zebrafish development. BMC Dev Biol. 2009 Apr 21;9(1):28. [Epub ahead of print].

Papillomavirus E2 induces senescence in HPV-positive cells via pRB- and p21(CIP)-dependent pathways.

Authors:
Wells SI, Francis DA, Karpova AY, Dowhanick JJ, Benson JD, Howley PM
Citation:
EMBO J. 2000 Nov 1;19(21):5762-71
Epub:
Not Epub
Abstract:
A hallmark of human papillomavirus (HPV) associated carcinogenesis is the integration of the viral DNA into the cellular genome...
Delivery Method:
Microinjection
Organism or Cell Type:
cell culture: HeLa cells
Citation Extract:
Wells SI, Francis DA, Karpova AY, Dowhanick JJ, Benson JD, Howley PM. Papillomavirus E2 induces senescence in HPV-positive cells via pRB- and p21(CIP)-dependent pathways.. EMBO J. 2000 Nov 1;19(21):5762-71.

Pkcα and Pkcβ are Positive Regulators of Thrombus Formation in vivo in a Zebrafish (Danio Rerio) Model of Thrombosis

Authors:
Williams CM, Feng Y, Martin P, Poole AW
Citation:
J Thromb Haemost. 2011 Sep 27. doi: 10.1111/j.1538-7836.2011.04520.x. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Background: The zebrafish (Danio rerio) is becoming an attractive model organism for assessment of gene function in thrombosis...
Organism or Cell Type:
zebrafish
Citation Extract:
Williams CM, Feng Y, Martin P, Poole AW. Pkcα and Pkcβ are Positive Regulators of Thrombus Formation in vivo in a Zebrafish (Danio Rerio) Model of Thrombosis. J Thromb Haemost. 2011 Sep 27. doi: 10.1111/j.1538-7836.2011.04520.x. [Epub ahead of print].

Platelet-derived growth factor receptor beta is critical for zebrafish intersegmental vessel formation

Authors:
Wiens KM, Lee HL, Shimada H, Metcalf AE, Chao MY, Lien CL
Citation:
PLoS One. 2010 Jun 25;5(6):e11324
Epub:
Not Epub
Abstract:
BACKGROUND: Platelet-derived growth factor receptor beta (PDGFRbeta) is a tyrosine kinase receptor known to affect vascular...
Organism or Cell Type:
zebrafish
Citation Extract:
Wiens KM, Lee HL, Shimada H, Metcalf AE, Chao MY, Lien CL. Platelet-derived growth factor receptor beta is critical for zebrafish intersegmental vessel formation. PLoS One. 2010 Jun 25;5(6):e11324.

Plumbing the mysteries of vascular development using the zebrafish

Authors:
Weinstein BM
Citation:
Semin Cell Dev Biol. 2002 Dec;13(6):515-22. Review
Epub:
Not Epub
Abstract:
The zebrafish has recently emerged as an advantageous model organism for studying how the stereotypic and evolutionarily...
Delivery Method:
not applicable
Organism or Cell Type:
zebrafish
Citation Extract:
Weinstein BM. Plumbing the mysteries of vascular development using the zebrafish. Semin Cell Dev Biol. 2002 Dec;13(6):515-22. Review.

Primary cilia membrane assembly is initiated by Rab11 and transport protein particle II (TRAPPII) complex-dependent trafficking of Rabin8 to the centrosome

Authors:
Westlake CJ, Baye LM, Nachury MV, Wright KJ, Ervin KE, Phu L, Chalouni C, Beck JS, Kirkpatrick DS, Slusarski DC, Sheffield VC, Scheller RH, Jackson PK
Citation:
Proc Natl Acad Sci U S A. 2011 Feb 15;108(7):2759-64. Epub 2011 Jan 27
Epub:
Not Epub
Abstract:
Sensory and signaling pathways are exquisitely organized in primary cilia. Bardet-Biedl syndrome (BBS) patients have...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Westlake CJ, Baye LM, Nachury MV, Wright KJ, Ervin KE, Phu L, Chalouni C, Beck JS, Kirkpatrick DS, Slusarski DC, Sheffield VC, Scheller RH, Jackson PK. Primary cilia membrane assembly is initiated by Rab11 and transport protein particle II (TRAPPII) complex-dependent trafficking of Rabin8 to the centrosome. Proc Natl Acad Sci U S A. 2011 Feb 15;108(7):2759-64. Epub 2011 Jan 27.

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