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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12371 scientific papers returned from the database with the search filters currently being used below.

A novel complex, RUNX1-MYEF2, represses hematopoietic genes in erythroid cells

Authors:
van Riel B, Pakozdi T, Brouwer R, Monteiro R, Tuladhar K, Franke V, Bryne JC, Jorna R, Rijkers EJ, van Ijcken W, Andrieu-Soler C, Demmers J, Patient R, Soler E, Lenhard B, Grosveld F
Citation:
Mol Cell Biol. 2012 Oct;32(19):3814-22. doi: 10.1128/MCB.05938-11. Epub 2012 Jul 16
Epub:
Not Epub
Abstract:
RUNX1 is known to be an essential transcription factor for generating hematopoietic stem cells (HSC), but much less is known...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
van Riel B, Pakozdi T, Brouwer R, Monteiro R, Tuladhar K, Franke V, Bryne JC, Jorna R, Rijkers EJ, van Ijcken W, Andrieu-Soler C, Demmers J, Patient R, Soler E, Lenhard B, Grosveld F. A novel complex, RUNX1-MYEF2, represses hematopoietic genes in erythroid cells. Mol Cell Biol. 2012 Oct;32(19):3814-22. doi: 10.1128/MCB.05938-11. Epub 2012 Jul 16.

A novel mechanism for the transcriptional regulation of Wnt signaling in development

Authors:
Vacik T, Stubbs JL, Lemke G
Citation:
Genes Dev. 2011 Sep 1;25(17):1783-95. Epub 2011 Aug 19.
Epub:
Not Epub
Abstract:
Axial patterning of the embryonic brain requires a precise balance between canonical Wnt signaling, which dorsalizes the...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Vacik T, Stubbs JL, Lemke G. A novel mechanism for the transcriptional regulation of Wnt signaling in development. Genes Dev. 2011 Sep 1;25(17):1783-95. Epub 2011 Aug 19..

A Spatial and Temporal Gradient of Fgf Differentially Regulates Distinct Stages of Neural Development in the Zebrafish Inner Ear

Authors:
Vemaraju S, Kantarci H, Padanad MS, Riley BB
Citation:
PLoS Genet. 2012;8(11):e1003068. doi:10.1371/journal.pgen.1003068
Epub:
Not Epub
Abstract:
Neuroblasts of the statoacoustic ganglion (SAG) initially form in the floor of the otic vesicle during a relatively brief...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Vemaraju S, Kantarci H, Padanad MS, Riley BB. A Spatial and Temporal Gradient of Fgf Differentially Regulates Distinct Stages of Neural Development in the Zebrafish Inner Ear. PLoS Genet. 2012;8(11):e1003068. doi:10.1371/journal.pgen.1003068.

A Zebrafish Model For The Shwachman-Diamond Syndrome (SDS)

Authors:
Venkatasubramani N, Mayer AN
Citation:
Pediatr Res. 2008 Apr;63(4):348-52.
Epub:
Not Epub
Abstract:
The Shwachman-Diamond Syndrome (SDS) is characterized by exocrine pancreatic insufficiency, neutrophil defect and skeletal...
Organism or Cell Type:
zebrafish
Citation Extract:
Venkatasubramani N, Mayer AN. A Zebrafish Model For The Shwachman-Diamond Syndrome (SDS). Pediatr Res. 2008 Apr;63(4):348-52..

Aberrant splicing in the ocular albinism type 1 gene (OA1/GPR143) is corrected in vitro by morpholino antisense oligonucleotides

Authors:
Vetrini F, Tammaro R, Bondanza S, Surace EM, Auricchio A, De Luca M, Ballabio A, Marigo V
Citation:
Hum Mutat. 2006 May;27(5):420-6
Epub:
Not Epub
Abstract:
An intronic point mutation was identified in the ocular albinism type 1 (OA1) gene (HUGO symbol, GPR143) in a family with the X...
Delivery Method:
Special Delivery
Organism or Cell Type:
Melanocyte from BA393 and BA399 patients
Citation Extract:
Vetrini F, Tammaro R, Bondanza S, Surace EM, Auricchio A, De Luca M, Ballabio A, Marigo V. Aberrant splicing in the ocular albinism type 1 gene (OA1/GPR143) is corrected in vitro by morpholino antisense oligonucleotides. Hum Mutat. 2006 May;27(5):420-6.

Abrogation of Prostaglandin E2/EP4 Signaling Impairs the Development of rag1+ Lymphoid Precursors in the Thymus of Zebrafish Embryos

Authors:
Villablanca EJ, Pistocchi A, Court FA, Cotelli F, Bordignon C, Allende ML, Traversari C, Russo V
Citation:
J Immunol. 2007 Jul 1;179(1):357-64
Epub:
Not Epub
Abstract:
PGE(2) is involved in a wide variety of physiological and pathological processes; however, deciphering its role in early...
Organism or Cell Type:
zebrafish
Citation Extract:
Villablanca EJ, Pistocchi A, Court FA, Cotelli F, Bordignon C, Allende ML, Traversari C, Russo V. Abrogation of Prostaglandin E2/EP4 Signaling Impairs the Development of rag1+ Lymphoid Precursors in the Thymus of Zebrafish Embryos. J Immunol. 2007 Jul 1;179(1):357-64.

AHR2 knockdown prevents PAH-mediated cardiac toxicity and XRE- and ARE-associated gene induction in zebrafish (Danio rerio)

Authors:
Van Tiem LA, Di Giulio RT
Citation:
Toxicol Appl Pharmacol. 2011 Aug 1;254(3):280-7. Epub 2011 May 10.
Epub:
Not Epub
Abstract:
Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous environmental contaminants often present in aquatic systems as complex...
Organism or Cell Type:
zebrafish
Citation Extract:
Van Tiem LA, Di Giulio RT. AHR2 knockdown prevents PAH-mediated cardiac toxicity and XRE- and ARE-associated gene induction in zebrafish (Danio rerio). Toxicol Appl Pharmacol. 2011 Aug 1;254(3):280-7. Epub 2011 May 10..

Antiviral activity of morpholino oligomers designed to block various aspects of Equine arteritis virus amplification in cell culture

Authors:
van den Born E, Stein DA, Iversen PL, Snijder EJ
Citation:
J Gen Virol. 2005 Nov;86(Pt 11):3081-90
Epub:
Not Epub
Abstract:
The antiviral efficacy of ten antisense phosphorodiamidate morpholino oligomers (PMOs) directed against Equine arteritis virus...
Delivery Method:
peptide-coupled
Organism or Cell Type:
cell culture: Vero-E6 cells
Citation Extract:
van den Born E, Stein DA, Iversen PL, Snijder EJ. Antiviral activity of morpholino oligomers designed to block various aspects of Equine arteritis virus amplification in cell culture. J Gen Virol. 2005 Nov;86(Pt 11):3081-90.

Apoptotic cells are cleared by directional migration and elmo1- dependent macrophage engulfment

Authors:
van Ham TJ, Kokel D, Peterson RT
Citation:
Curr Biol. 2012 May 8;22(9):830-6. doi: 10.1016/j.cub.2012.03.027. Epub 2012 Apr 12
Epub:
Not Epub
Abstract:
Apoptotic cell death is essential for development and tissue homeostasis [1, 2]. Failure to clear apoptotic cells can...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
van Ham TJ, Kokel D, Peterson RT. Apoptotic cells are cleared by directional migration and elmo1- dependent macrophage engulfment. Curr Biol. 2012 May 8;22(9):830-6. doi: 10.1016/j.cub.2012.03.027. Epub 2012 Apr 12.

Atypical Mowat-Wilson patient confirms the importance of the novel association between ZFHX1B/SIP1 and NuRD corepressor complex

Authors:
Verstappen G, van Grunsven LA, Michiels C, Van de Putte T, Souopgui J, Van Damme J, Bellefroid E, Vandekerckhove J, Huylebroeck D
Citation:
Hum Mol Genet. 2008 Apr 15;17(8):1175-83. Epub 2008 Jan 8
Epub:
Not Epub
Abstract:
Mutations in ZFHX1B cause Mowat-Wilson syndrome (MWS) but the precise mechanisms underlying the aberrant functions of mutant...
Organism or Cell Type:
Xenopus
Citation Extract:
Verstappen G, van Grunsven LA, Michiels C, Van de Putte T, Souopgui J, Van Damme J, Bellefroid E, Vandekerckhove J, Huylebroeck D. Atypical Mowat-Wilson patient confirms the importance of the novel association between ZFHX1B/SIP1 and NuRD corepressor complex. Hum Mol Genet. 2008 Apr 15;17(8):1175-83. Epub 2008 Jan 8.

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