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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

c-MYC antisense phosphosphorodiamidate morpholino oligomer inhibits lung metastasis in a murine tumor model

Authors:
Sekhon HS, London CA, Sekhon M, Iversen PL, Devi GR
Citation:
Lung Cancer. 2008 Jun;60(3):347-54. Epub 2007 Dec 21.
Epub:
Not Epub
Abstract:
BACKGROUND: c-MYC amplification and overexpression has been correlated with progression and chemotherapy resistance in lung...
Delivery Method:
in vivo: subcutaneous (s.c.) injection
Organism or Cell Type:
Mouse: LLC1 syngeneic tumor model
Citation Extract:
Sekhon HS, London CA, Sekhon M, Iversen PL, Devi GR. c-MYC antisense phosphosphorodiamidate morpholino oligomer inhibits lung metastasis in a murine tumor model. Lung Cancer. 2008 Jun;60(3):347-54. Epub 2007 Dec 21..

Cardiac troponin T is essential in sarcomere assembly and cardiac contractility

Authors:
Sehnert AJ, Huq A, Weinstein BM, Walker C, Fishman M, Stainier DYR.
Citation:
Nat Genet 2002 May;31(1):106-10
Epub:
Not Epub
Abstract:
Mutations of the gene (TNNT2) encoding the thin-filament contractile protein cardiac troponin T are responsible for 15% of all...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sehnert AJ, Huq A, Weinstein BM, Walker C, Fishman M, Stainier DYR.. Cardiac troponin T is essential in sarcomere assembly and cardiac contractility. Nat Genet 2002 May;31(1):106-10.

Characterization of Danio rerio Nanog and functional comparison to Xenopus Vents

Authors:
Schuff M, Siegel D, Philipp M, Bundschu K, Heymann N, Donow C, Knöchel W
Citation:
Stem Cells Dev. 2012 May 20;21(8):1225-38. doi: 10.1089/scd.2011.0285. Epub 2011 Oct 3
Epub:
Not Epub
Abstract:
Nanog is a homeodomain transcription factor associated with the acquisition of pluripotency. Genome analyses of lower and...
Delivery Method:
Microinjection and cell-free system
Organism or Cell Type:
zebrafish
Citation Extract:
Schuff M, Siegel D, Philipp M, Bundschu K, Heymann N, Donow C, Knöchel W. Characterization of Danio rerio Nanog and functional comparison to Xenopus Vents. Stem Cells Dev. 2012 May 20;21(8):1225-38. doi: 10.1089/scd.2011.0285. Epub 2011 Oct 3.

Ciliated sensory hair cell formation and function require the F-BAR protein syndapin I and the WH2 domain-based actin nucleator Cobl

Authors:
Schüler S, Hauptmann J, Perner B, Kessels MM, Englert C, Qualmann B
Citation:
J Cell Sci. 2012 Nov 30. [Epub ahead of print]
Epub:
Not Epub
Abstract:
During development, general body plan information must be translated into distinct morphologies of individual cells. Shaping...
Organism or Cell Type:
zebrafish
Citation Extract:
Schüler S, Hauptmann J, Perner B, Kessels MM, Englert C, Qualmann B. Ciliated sensory hair cell formation and function require the F-BAR protein syndapin I and the WH2 domain-based actin nucleator Cobl. J Cell Sci. 2012 Nov 30. [Epub ahead of print].

Completing the set of h/E(spl) cyclic genes in zebrafish: her12 and her15 reveal novel modes of expression and contribute to the segmentation clock

Authors:
Shankaran SS, Sieger D, Schroter C, Czepe C, Pauly MC, Laplante MA, Becker TS, Oates AC, Gajewski M
Citation:
Dev Biol. 2007 Apr 15;304(2):615-32. Epub 2007 Jan 9.
Epub:
Not Epub
Abstract:
Somitogenesis is the key developmental process that lays down the framework for a metameric body in vertebrates. Somites are...
Organism or Cell Type:
zebrafish
Citation Extract:
Shankaran SS, Sieger D, Schroter C, Czepe C, Pauly MC, Laplante MA, Becker TS, Oates AC, Gajewski M. Completing the set of h/E(spl) cyclic genes in zebrafish: her12 and her15 reveal novel modes of expression and contribute to the segmentation clock. Dev Biol. 2007 Apr 15;304(2):615-32. Epub 2007 Jan 9..

Conserved functions of Ikaros in vertebrate lymphocyte development: genetic evidence for distinct larval and adult phases of T cell development and two lineages of B cells in zebrafish

Authors:
Schorpp M, Bialecki M, Diekhoff D, Walderich B, Odenthal J, Maischein HM, Zapata AG, Boehm T
Citation:
J Immunol. 2006 Aug 15;177(4):2463-76
Epub:
Not Epub
Abstract:
Zebrafish has been advocated as an alternative animal model to study lymphocyte development, although the similarities in the...
Citation Extract:
Schorpp M, Bialecki M, Diekhoff D, Walderich B, Odenthal J, Maischein HM, Zapata AG, Boehm T. Conserved functions of Ikaros in vertebrate lymphocyte development: genetic evidence for distinct larval and adult phases of T cell development and two lineages of B cells in zebrafish. J Immunol. 2006 Aug 15;177(4):2463-76.

Core fucosylation is required for midline patterning during zebrafish development.

Authors:
Seth A, Machingo QJ, Fritz A, Shur BD
Citation:
Dev Dyn. 2010 Nov 10. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Complex carbohydrates represent one of the most polymorphic classes of macromolecules, but their functions during embryonic...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Seth A, Machingo QJ, Fritz A, Shur BD. Core fucosylation is required for midline patterning during zebrafish development.. Dev Dyn. 2010 Nov 10. [Epub ahead of print].

Critical Role for TWIST1 in the Induction of Human Uterine Decidualization

Authors:
Schroeder JK, Kessler CA, Handwerger S
Citation:
Endocrinology. 2011 Nov;152(11):4368-76. doi: 10.1210/en.2011-1140. Epub 2011 Sep 13. PMID: 21914771; PMCID: PMC3199000
Epub:
Not Epub
Abstract:
The importance of the transcription factor TWIST1 for uterine decidualization was examined in human uterine fibroblast (HUF)...
Link:
https://pmc.ncbi.nlm.nih.gov/articles/PMC3199000/
Delivery Method:
cell bathing
Organism or Cell Type:
cell culture: human uterine fibroblasts
Citation Extract:
Schroeder JK, Kessler CA, Handwerger S. Critical Role for TWIST1 in the Induction of Human Uterine Decidualization. Endocrinology. 2011 Nov;152(11):4368-76. doi: 10.1210/en.2011-1140. Epub 2011 Sep 13. PMID: 21914771; PMCID: PMC3199000.

Depletion of Zebrafish Titin Reduces Cardiac Contractility by Disrupting the Assembly of Z-Discs and A-Bands

Authors:
Seeley M, Huang W, Chen Z, Wolff WO, Lin X, Xu X
Citation:
Circ Res. 2007 Feb 2;100(2):238-45. Epub 2006 Dec 14.
Epub:
Not Epub
Abstract:
The genetic study of titin has been notoriously difficult because of its size and complicated alternative splicing routes. Here...
Organism or Cell Type:
zebrafish
Citation Extract:
Seeley M, Huang W, Chen Z, Wolff WO, Lin X, Xu X. Depletion of Zebrafish Titin Reduces Cardiac Contractility by Disrupting the Assembly of Z-Discs and A-Bands. Circ Res. 2007 Feb 2;100(2):238-45. Epub 2006 Dec 14..

Development of a general methodology for labelling peptide-morpholino oligonucleotide conjugates using alkyne-azide click chemistry

Authors:
Shabanpoor F, Gait MJ
Citation:
Chem Commun (Camb). 2013 Nov 11;49(87):10260-2. doi: 10.1039/c3cc46067c
Epub:
Not Epub
Abstract:
We describe a general methodology for fluorescent labelling of peptide conjugates of phosphorodiamidate morpholino...
Link:
http://pubs.rsc.org/en/Content/ArticleLanding/2013/CC/C3CC46067C#!divAbstract
Delivery Method:
peptide-coupled
Organism or Cell Type:
cell culture: mouse H2K/mdx myoblasts
Citation Extract:
Shabanpoor F, Gait MJ. Development of a general methodology for labelling peptide-morpholino oligonucleotide conjugates using alkyne-azide click chemistry. Chem Commun (Camb). 2013 Nov 11;49(87):10260-2. doi: 10.1039/c3cc46067c.

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