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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12419 scientific papers returned from the database with the search filters currently being used below.
There are 12419 scientific papers returned from the database with the search filters currently being used below.
Retinal regeneration in adult zebrafish requires regulation of TGFβ signaling
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Citation:
Glia. 2013 Oct;61(10):1687-97. doi: 10.1002/glia.22549. Epub 2013 Aug 5 Epub:
Not Epub Abstract:
Müller glia are the resident radial glia in the vertebrate retina. The response of mammalian Müller glia to retinal damage... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Lenkowski JR, Qin Z, Sifuentes CJ, Thummel R, Soto CM, Moens CB, Raymond PA. Retinal regeneration in adult zebrafish requires regulation of TGFβ signaling. Glia. 2013 Oct;61(10):1687-97. doi: 10.1002/glia.22549. Epub 2013 Aug 5. |
Mutations in STX1B, encoding a presynaptic protein, cause fever-associated epilepsy syndromes
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Citation:
Nat Genet. 2014;[Epub ahead pf print] doi:10.1038/ng.3130 Epub:
Yes Abstract:
Febrile seizures affect 2-4% of all children and have a strong genetic component. Recurrent mutations in three main genes (... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Schubert J, Siekierska A, Langlois M, May P, Huneau C, Becker F, Muhle H, Suls A, Lemke JR, de Kovel CGF, Thiele H, Konrad K, Kawalia A, Toliat MR, Sander T, Rüschendorf F, Caliebe A, Nagel I, Kohl B, Kecskés A, Jacmin M, Hardies K, Weckhuysen S, Riesch E, Dorn T, Brilstra EH, Baulac S, Møller RS, Hjalgrim H, Koeleman BPC, EuroEPINOMICS RES Consortium, Jurkat-Rott K, Lehman-Horn F, Roach JC, Glusman G, Hood L, Galas DJ, Martin B, de Witte PAM, Biskup S, De Jonghe P, Helbig I, Balling R, Nürnberg P, Crawford AD, Esguerra CV, Weber YG, Lerche H. Mutations in STX1B, encoding a presynaptic protein, cause fever-associated epilepsy syndromes. Nat Genet. 2014;[Epub ahead pf print] doi:10.1038/ng.3130. |
Bicaudal-C is required for the formation of anterior neurogenic ectoderm in the sea urchin embryo
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Citation:
Sci Rep. 2014 Oct 31;4:6852. doi: 10.1038/srep06852 Epub:
Not Epub Abstract:
bicaudal-C (bicC) mRNA encodes a protein containing RNA-binding domains that is reported to be maternally present with... Delivery Method:
microinjection Organism or Cell Type:
Hemicentrotus pulcherrimus (sea urchin) Citation Extract: Yaguchi S, Yaguchi J, Inaba K. Bicaudal-C is required for the formation of anterior neurogenic ectoderm in the sea urchin embryo. Sci Rep. 2014 Oct 31;4:6852. doi: 10.1038/srep06852. |
Homozygous splice mutation in CWF19L1 in a Turkish family with recessive ataxia syndrome
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Citation:
Neurology. 2014 Oct 31. pii: 10.1212/WNL.0000000000001053. [Epub ahead of print] Epub:
Yes Abstract:
OBJECTIVE: To elucidate the genetic cause of a rare recessive ataxia presented by 2 siblings from a consanguineous Turkish... Organism or Cell Type:
zebrafish Citation Extract: Burns R, Majczenko K, Xu J, Peng W, Yapici Z, Dowling JJ, Li JZ, Burmeister M. Homozygous splice mutation in CWF19L1 in a Turkish family with recessive ataxia syndrome. Neurology. 2014 Oct 31. pii: 10.1212/WNL.0000000000001053. [Epub ahead of print]. |
A Spaetzle-like role for nerve growth factor β in vertebrate immunity to Staphylococcus aureus
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Citation:
Science. 2014;346(6209):641-6. doi:10.1126/science.1258705 Epub:
Not Epub Abstract:
Many key components of innate immunity to infection are shared between Drosophila and humans. However, the fly Toll ligand... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Hepburn L, Prajsnar TK, Klapholz C, Moreno P, Loynes CA, Ogryzko NV, Brown K, Schiebler M, Hegyi K, Antrobus R, Hammond KL, Connolly J, Ochoa B, Bryant C, Otto M, Surewaard B, Seneviratne SL, Grogono DM, Cachat J, Ny T, Kaser A, Török ME, Peacock SJ, Holden M, Blundell T, Wang L, Ligoxygakis P, Minichiello L, Woods CG, Foster SJ, Renshaw SA, Floto RA. A Spaetzle-like role for nerve growth factor β in vertebrate immunity to Staphylococcus aureus. Science. 2014;346(6209):641-6. doi:10.1126/science.1258705. |
A Recurrent CEP120 Mutation in Jeune Asphyxiating Thoracic Dystrophy Expands the Role of Centriolar Proteins in Skeletal Ciliopathies
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Citation:
Hum Mol Genet. 2014;[Epub ahead of print] doi:10.1093/hmg/ddu555 Epub:
Yes Abstract:
Jeune asphyxiating thoracic dystrophy (JATD) is a skeletal dysplasia characterized by a small thoracic cage and a range of... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Shaheen R, Schmidts M, Faqeih E, Hashem A, Lausch E, Holder I, Superti-Furga A, UK10 K consortium, Mitchison HM, Almoisheer A, Alamro R, Alshiddi T, Alzahrani F, Beales PL, Alkuraya FS. A Recurrent CEP120 Mutation in Jeune Asphyxiating Thoracic Dystrophy Expands the Role of Centriolar Proteins in Skeletal Ciliopathies. Hum Mol Genet. 2014;[Epub ahead of print] doi:10.1093/hmg/ddu555 . |
Fgf16 Is Required for Specification of GABAergic Neurons and Oligodendrocytes in the Zebrafish Forebrain
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Citation:
PLoS One. 2014 Oct 30;9(10):e110836. doi: 10.1371/journal.pone.0110836. eCollection 2014 Epub:
Not Epub Abstract:
Fibroblast growth factor (Fgf) signaling plays crucial roles in various developmental processes including those in the brain.... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Miyake A, Chitose T, Kamei E, Murakami A, Nakayama Y, Konishi M, Itoh N. Fgf16 Is Required for Specification of GABAergic Neurons and Oligodendrocytes in the Zebrafish Forebrain. PLoS One. 2014 Oct 30;9(10):e110836. doi: 10.1371/journal.pone.0110836. eCollection 2014. |
Differentiation between temporary and real non-clearability of biotinylated IgG antibody by avidin in mice
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Citation:
Front Pharmacol. 2014 Jul 24;5:172. doi: 10.3389/fphar.2014.00172. eCollection 2014 Epub:
Not Epub Abstract:
Although an increasing number of antibody conjugates are being used in the clinic, there remain many unmet needs in antibody... Delivery Method:
pretargeting Organism or Cell Type:
mice Citation Extract: Dou S, Virostko J, Rusckowski M, Greiner DL, Powers AC, Liu G. Differentiation between temporary and real non-clearability of biotinylated IgG antibody by avidin in mice. Front Pharmacol. 2014 Jul 24;5:172. doi: 10.3389/fphar.2014.00172. eCollection 2014. |
Interaction of infectious spleen and kidney necrosis virus ORF119L with PINCH leads to dominant-negative inhibition of integrin-linked kinase and cardiovascular defects in zebrafish
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Citation:
J Virol. 2015 Jan;89(1):763-75. doi: 10.1128/JVI.01955-14. Epub 2014 Oct 29. PMID: 25355883; PMCID: PMC4301147 Epub:
Yes Abstract:
Infectious spleen and kidney necrosis virus (ISKNV) is the type species of the Megalocytivirus genus, Iridoviridae family,... Delivery Method:
injection Organism or Cell Type:
zebrafish Citation Extract: Yuan JM, He BL, Yang LY, Guo CJ, Weng SP, Li SC, He JG. Interaction of infectious spleen and kidney necrosis virus ORF119L with PINCH leads to dominant-negative inhibition of integrin-linked kinase and cardiovascular defects in zebrafish. J Virol. 2015 Jan;89(1):763-75. doi: 10.1128/JVI.01955-14. Epub 2014 Oct 29. PMID: 25355883; PMCID: PMC4301147. |
Antisense Oligonucleotide-mediated Suppression of Muscle Glycogen Synthase 1 Synthesis as an Approach for Substrate Reduction Therapy of Pompe Disease
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Citation:
Mol Ther Nucleic Acids. 2014 Oct 28;3:e206. doi: 10.1038/mtna.2014.57 Epub:
Not Epub Abstract:
Pompe disease is an autosomal recessive disorder caused by a deficiency of acid α-glucosidase (GAA; EC 3.2.1.20) and the... Delivery Method:
injection & electroporation or peptide-linked Organism or Cell Type:
mice Citation Extract: Clayton NP, Nelson CA, Weeden T, Taylor KM, Moreland RJ, Scheule RK, Phillips L, Leger AJ, Cheng SH, Wentworth BM. Antisense Oligonucleotide-mediated Suppression of Muscle Glycogen Synthase 1 Synthesis as an Approach for Substrate Reduction Therapy of Pompe Disease. Mol Ther Nucleic Acids. 2014 Oct 28;3:e206. doi: 10.1038/mtna.2014.57. |