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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12419 scientific papers returned from the database with the search filters currently being used below.

Repressing Notch Signaling and Expressing TNFα Are Sufficient to Mimic Retinal Regeneration by Inducing Müller Glial Proliferation to Generate Committed Progenitor Cells

Authors:
Conner C, Ackerman KM, Lahne M, Hobgood JS, Hyde DR
Citation:
J Neurosci. 2014;34(43):14403-14419. doi:10.1523/JNEUROSCI.0498-14.2014
Epub:
Not Epub
Abstract:
Retinal damage in teleosts, unlike mammals, induces robust Müller glia-mediated regeneration of lost neurons. We examined...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Conner C, Ackerman KM, Lahne M, Hobgood JS, Hyde DR. Repressing Notch Signaling and Expressing TNFα Are Sufficient to Mimic Retinal Regeneration by Inducing Müller Glial Proliferation to Generate Committed Progenitor Cells. J Neurosci. 2014;34(43):14403-14419. doi:10.1523/JNEUROSCI.0498-14.2014.

CHD8 regulates neurodevelopmental pathways associated with autism spectrum disorder in neural progenitors

Authors:
Sugathan A, Biagioli M, Golzio C, Erdin S, Blumenthal I, Manavalan P, Ragavendran A, Brand H, Lucente D, Miles J, Sheridan SD, Stortchevoi A, Kellis M, Haggarty SJ, Katsanis N, Gusella JF, Talkowski ME
Citation:
PNAS. 2014;111(42):E4468-E4477. published ahead of print October 7, 2014, doi:10.1073/pnas.1405266111
Epub:
Yes
Abstract:
Truncating mutations of chromodomain helicase DNA-binding protein 8 (CHD8), and of many other genes with diverse functions, are...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sugathan A, Biagioli M, Golzio C, Erdin S, Blumenthal I, Manavalan P, Ragavendran A, Brand H, Lucente D, Miles J, Sheridan SD, Stortchevoi A, Kellis M, Haggarty SJ, Katsanis N, Gusella JF, Talkowski ME. CHD8 regulates neurodevelopmental pathways associated with autism spectrum disorder in neural progenitors. PNAS. 2014;111(42):E4468-E4477. published ahead of print October 7, 2014, doi:10.1073/pnas.1405266111.

Whole-exome Sequencing Identifies a Variant in TMEM132E Causing Autosomal-Recessive Nonsyndromic Hearing Loss DFNB99

Authors:
Li J, Zhao X, Xin Q, Shan S, Jiang B, Jin Y, Yuan H, Dai P, Xiao R, Zhang Q, Xiao J, Shao C, Gong Y, Liu Q
Citation:
Hum Mutat. 2014 Oct 21. doi: 10.1002/humu.22712. [Epub ahead of print]
Epub:
Yes
Abstract:
Autosomal recessive non-syndromic hearing loss (ARNSHL) features a high degree of genetic heterogeneity. Many genes responsible...
Organism or Cell Type:
zebrafish, Xenopus
Citation Extract:
Li J, Zhao X, Xin Q, Shan S, Jiang B, Jin Y, Yuan H, Dai P, Xiao R, Zhang Q, Xiao J, Shao C, Gong Y, Liu Q. Whole-exome Sequencing Identifies a Variant in TMEM132E Causing Autosomal-Recessive Nonsyndromic Hearing Loss DFNB99. Hum Mutat. 2014 Oct 21. doi: 10.1002/humu.22712. [Epub ahead of print].

Orphan G-Protein Coupled Receptor 22 (Gpr22) Regulates Cilia Length and Structure in the Zebrafish Kupffer’s Vesicle

Authors:
Verleyen D, Luyten FP, Tylzanowski P
Citation:
PLoS ONE. 2014;9(10):e110484. doi:10.1371/journal.pone.0110484
Epub:
Not Epub
Abstract:
GPR22 is an orphan G protein-coupled receptor (GPCR). Since the ligand of the receptor is currently unknown, its biological...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Verleyen D, Luyten FP, Tylzanowski P. Orphan G-Protein Coupled Receptor 22 (Gpr22) Regulates Cilia Length and Structure in the Zebrafish Kupffer’s Vesicle. PLoS ONE. 2014;9(10):e110484. doi:10.1371/journal.pone.0110484.

Kctd12 and Ulk2 Partner to Regulate Dendritogenesis and Behavior in the Habenular Nuclei

Authors:
Lee S, Page-McCaw P, Gamse JT
Citation:
PLoS ONE. 2014;9(10):e110280. doi:10.1371/journal.pone.0110280
Epub:
Not Epub
Abstract:
The habenular nuclei of the limbic system regulate responses, such as anxiety, to aversive stimuli in the environment. The...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lee S, Page-McCaw P, Gamse JT. Kctd12 and Ulk2 Partner to Regulate Dendritogenesis and Behavior in the Habenular Nuclei. PLoS ONE. 2014;9(10):e110280. doi:10.1371/journal.pone.0110280.

Endoplasmic Reticulum Resident Protein 44 (ERp44) Deficiency in Mice and Zebrafish Leads to Cardiac Developmental and Functional Defects

Authors:
Wang D-Y, Abbasi C, El‐Rass S, Yuanjun Li JY, Dawood F, Naito K, Sharma P, Bousette N, Singh S, Backx PH, Cox B, Wen X-Y, Liu PP, Gramolini AO
Citation:
J Am Heart Assoc. 2014;3:e001018, originally published October 20, 2014, doi:10.1161/JAHA.114.001018
Epub:
Not Epub
Abstract:
Background: Endoplasmic reticulum (ER) resident protein 44 (ERp44) is a member of the protein disulfide isomerase family, is...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wang D-Y, Abbasi C, El‐Rass S, Yuanjun Li JY, Dawood F, Naito K, Sharma P, Bousette N, Singh S, Backx PH, Cox B, Wen X-Y, Liu PP, Gramolini AO. Endoplasmic Reticulum Resident Protein 44 (ERp44) Deficiency in Mice and Zebrafish Leads to Cardiac Developmental and Functional Defects. J Am Heart Assoc. 2014;3:e001018, originally published October 20, 2014, doi:10.1161/JAHA.114.001018 .

A Novel Test for Recessive Contributions to Complex Diseases Implicates Bardet-Biedl Syndrome Gene BBS10 in Idiopathic Type 2 Diabetes and Obesity

Authors:
Lim ET, Liu YP, Chan Y, Tiinamaija T, Käräjämäki AM, Madsen E, Go-T2D Consortium, Altshuler DM, Raychaudhuri S, Groop L, Flannick J, Hirschhorn JN, Katsanis N, Daly MJ
Citation:
Am J Hum Genet. 2014;[Epub ahead of print] doi:10.1016/j.ajhg.2014.09.015
Epub:
Yes
Abstract:
Rare-variant association studies in common, complex diseases are customarily conducted under an additive risk model in both...
Organism or Cell Type:
zebrafish
Citation Extract:
Lim ET, Liu YP, Chan Y, Tiinamaija T, Käräjämäki AM, Madsen E, Go-T2D Consortium, Altshuler DM, Raychaudhuri S, Groop L, Flannick J, Hirschhorn JN, Katsanis N, Daly MJ. A Novel Test for Recessive Contributions to Complex Diseases Implicates Bardet-Biedl Syndrome Gene BBS10 in Idiopathic Type 2 Diabetes and Obesity. Am J Hum Genet. 2014;[Epub ahead of print] doi:10.1016/j.ajhg.2014.09.015.

Effects of Vivo Morpholino Knockdown of Lateral Hypothalamus Orexin/Hypocretin on Renewal of Alcohol Seeking

Authors:
Prasad AA, McNally GP
Citation:
PLoS ONE. 2014;9(10):e110385. doi:10.1371/journal.pone.0110385
Epub:
Not Epub
Abstract:
Two experiments used vivo morpholinos to assess the role of orexin/hypocretin in ABA renewal of extinguished alcohol seeking....
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
rat
Citation Extract:
Prasad AA, McNally GP. Effects of Vivo Morpholino Knockdown of Lateral Hypothalamus Orexin/Hypocretin on Renewal of Alcohol Seeking. PLoS ONE. 2014;9(10):e110385. doi:10.1371/journal.pone.0110385.

Zebrafish fgf10b has a Complementary Function to fgf10a in Liver and Pancreas Development

Authors:
Yan C, Zheng W, Gong Z
Citation:
Mar Biotechnol (NY). 2014 Oct 18. [Epub ahead of print]
Epub:
Yes
Abstract:
Fgf10 is a critical growth factor in mammals for development of endodermal organs such as the liver, pancreas, lung, and gut....
Organism or Cell Type:
zebrafish
Citation Extract:
Yan C, Zheng W, Gong Z. Zebrafish fgf10b has a Complementary Function to fgf10a in Liver and Pancreas Development. Mar Biotechnol (NY). 2014 Oct 18. [Epub ahead of print].

Analyzing the role of heparan sulfate proteoglycans in axon guidance in vivo in zebrafish

Authors:
Poulain FE
Citation:
Methods Mol Biol. 2015;1229:469-82. doi: 10.1007/978-1-4939-1714-3_36
Epub:
Not Epub
Abstract:
One of the most fascinating questions in the field of neurobiology is to understand how neuronal connections are properly...
Organism or Cell Type:
zebrafish
Citation Extract:
Poulain FE. Analyzing the role of heparan sulfate proteoglycans in axon guidance in vivo in zebrafish. Methods Mol Biol. 2015;1229:469-82. doi: 10.1007/978-1-4939-1714-3_36.

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