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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12371 scientific papers returned from the database with the search filters currently being used below.

Initiation of synapse formation by Wnt-induced MuSK endocytosis

Authors:
Gordon LR, Gribble KD, Syrett CM, Granato M
Citation:
Development. 2012;139:1023-1033. doi:10.1242/dev.071555
Epub:
Not Epub
Abstract:
In zebrafish, the MuSK receptor initiates neuromuscular synapse formation by restricting presynaptic growth cones and...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Gordon LR, Gribble KD, Syrett CM, Granato M. Initiation of synapse formation by Wnt-induced MuSK endocytosis. Development. 2012;139:1023-1033. doi:10.1242/dev.071555.

IQGAP1 Functions as a Modulator of Dishevelled Nuclear Localization in Wnt Signaling

Authors:
Goto T, Sato A, Shimizu M, Adachi S, Satoh K, Iemura S-I, Natsume T, Shibuya H
Citation:
PLoS ONE. 2013;8(4):e60865. doi:10.1371/journal.pone.0060865
Epub:
Not Epub
Abstract:
Dishevelled (DVL) is a central factor in the Wnt signaling pathway, which is highly conserved among various organisms. DVL...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Goto T, Sato A, Shimizu M, Adachi S, Satoh K, Iemura S-I, Natsume T, Shibuya H. IQGAP1 Functions as a Modulator of Dishevelled Nuclear Localization in Wnt Signaling. PLoS ONE. 2013;8(4):e60865. doi:10.1371/journal.pone.0060865.

KCTD13 is a major driver of mirrored neuroanatomical phenotypes of the 16p11.2 copy number variant

Authors:
Golzio C, Willer J, Talkowski ME, Oh EC, Taniguchi Y, Jacquemont S, Reymond A, Sun M, Sawa A, Gusella JF, Kamiya A, Beckmann JS, Katsanis N
Citation:
Nature. 2011;485:363–7. doi:10.1038/nature11091
Epub:
Not Epub
Abstract:
Copy number variants (CNVs) are major contributors to genetic disorders. We have dissected a region of the 16p11.2 chromosome—...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Golzio C, Willer J, Talkowski ME, Oh EC, Taniguchi Y, Jacquemont S, Reymond A, Sun M, Sawa A, Gusella JF, Kamiya A, Beckmann JS, Katsanis N. KCTD13 is a major driver of mirrored neuroanatomical phenotypes of the 16p11.2 copy number variant. Nature. 2011;485:363–7. doi:10.1038/nature11091.

Knockdown of the intraflagellar transport protein IFT46 stimulates selective gene expression in mouse chondrocytes and affects early development in zebrafish

Authors:
Gouttenoire J, Valcourt U, Bougault C, Aubert-Foucher E, Arnaud E, Giraud L, Mallein-Gerin F
Citation:
J Biol Chem. 2007 Oct 19;282(42):30960-73. Epub 2007 Aug 24
Epub:
Not Epub
Abstract:
Bone Morphogenetic Proteins (BMPs) act as multifonctional regulators in morphogenesis during development. In particular they...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Gouttenoire J, Valcourt U, Bougault C, Aubert-Foucher E, Arnaud E, Giraud L, Mallein-Gerin F. Knockdown of the intraflagellar transport protein IFT46 stimulates selective gene expression in mouse chondrocytes and affects early development in zebrafish. J Biol Chem. 2007 Oct 19;282(42):30960-73. Epub 2007 Aug 24.

MicroRNA regulation of the paired-box transcription factor Pax3 confers robustness to developmental timing of myogenesis

Authors:
Goljanek-Whysall K, Sweetman D, Abu-Elmagd M, Chapnik E, Dalmay T, Hornstein E, Münsterberg A
Citation:
PNAS USA. 2011 Jul 19;108(29):11936-41. Epub 2011 Jul 5.
Epub:
Not Epub
Abstract:
Commitment of progenitors in the dermomyotome to myoblast fate is the first step in establishing the body musculature. Pax3 is...
Citation Extract:
Goljanek-Whysall K, Sweetman D, Abu-Elmagd M, Chapnik E, Dalmay T, Hornstein E, Münsterberg A. MicroRNA regulation of the paired-box transcription factor Pax3 confers robustness to developmental timing of myogenesis. PNAS USA. 2011 Jul 19;108(29):11936-41. Epub 2011 Jul 5..

MicroRNA-340-mediated degradation of microphthalmia-associated transcription factor mRNA is inhibited by the coding region determinant-binding protein

Authors:
Goswami S, Tarapore RS, Teslaa JJ, Grinblat Y, Setaluri V, Spiegelman VS
Citation:
J Biol Chem. 2010 Jul 2;285(27):20532-40. Epub 2010 May 3
Epub:
Not Epub
Abstract:
Alternative cleavage and polyadenylation generate multiple transcript variants of mRNA isoforms with different length of 3...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Goswami S, Tarapore RS, Teslaa JJ, Grinblat Y, Setaluri V, Spiegelman VS. MicroRNA-340-mediated degradation of microphthalmia-associated transcription factor mRNA is inhibited by the coding region determinant-binding protein. J Biol Chem. 2010 Jul 2;285(27):20532-40. Epub 2010 May 3.

Molecular Mechanisms in Morpholino-DNA Surface Hybridization

Authors:
Gong P, Wang K, Liu Y, Shepard K, Levicky R
Citation:
J Am Chem Soc. 2010 Jun 24. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Synthetic nucleic acid mimics provide opportunity for redesigning the specificity and affinity of hybridization with natural...
Citation Extract:
Gong P, Wang K, Liu Y, Shepard K, Levicky R. Molecular Mechanisms in Morpholino-DNA Surface Hybridization. J Am Chem Soc. 2010 Jun 24. [Epub ahead of print].

NAD+ Biosynthesis Ameliorates a Zebrafish Model of Muscular Dystrophy

Authors:
Goody MF, Kelly MW, Reynolds CJ, Khalil A, Crawford BD, Henry CA
Citation:
PLoS Biol. 2012;10(10): e1001409. doi:10.1371/journal.pbio.1001409
Epub:
Not Epub
Abstract:
Muscular dystrophies are common, currently incurable diseases. A subset of dystrophies result from genetic disruptions in...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Goody MF, Kelly MW, Reynolds CJ, Khalil A, Crawford BD, Henry CA. NAD+ Biosynthesis Ameliorates a Zebrafish Model of Muscular Dystrophy. PLoS Biol. 2012;10(10): e1001409. doi:10.1371/journal.pbio.1001409.

Nrk2b-mediated NAD+ production regulates cell adhesion and is required for muscle morphogenesis in vivo: Nrk2b and NAD+ in muscle morphogenesis

Authors:
Goody MF, Kelly MW, Lessard KN, Khalil A, Henry CA
Citation:
Dev Biol. 2010 Aug 15;344(2):809-26. Epub 2010 Jun 8
Epub:
Not Epub
Abstract:
Cell-matrix adhesion complexes (CMACs) play fundamental roles during morphogenesis. Given the ubiquitous nature of CMACs and...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Goody MF, Kelly MW, Lessard KN, Khalil A, Henry CA. Nrk2b-mediated NAD+ production regulates cell adhesion and is required for muscle morphogenesis in vivo: Nrk2b and NAD+ in muscle morphogenesis. Dev Biol. 2010 Aug 15;344(2):809-26. Epub 2010 Jun 8.

OTUB1 modulates c-IAP1 stability to regulate signalling pathways

Authors:
Goncharov T, Niessen K, de Almagro MC, Izrael-Tomasevic A, Fedorova AV, Varfolomeev E, Arnott D, Deshayes K, Kirkpatrick DS, Vucic D
Citation:
EMBO J. 2013;[Epub ahead of print] doi:10.1038/emboj.2013.62
Epub:
Not Epub
Abstract:
The cellular inhibitor of apoptosis (c-IAP) proteins are E3 ubiquitin ligases that are critical regulators of tumour necrosis...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Goncharov T, Niessen K, de Almagro MC, Izrael-Tomasevic A, Fedorova AV, Varfolomeev E, Arnott D, Deshayes K, Kirkpatrick DS, Vucic D. OTUB1 modulates c-IAP1 stability to regulate signalling pathways. EMBO J. 2013;[Epub ahead of print] doi:10.1038/emboj.2013.62.

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