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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12371 scientific papers returned from the database with the search filters currently being used below.

Activation of P-TEFb by cAMP-PKA signaling in autosomal dominant polycystic kidney disease

Authors:
Sun Y, Liu Z, Cao X, Lu Y, Mi Z, He C, Liu J, Zheng Z, Li MJ, Li T, Xu D, Wu M, Cao Y, Li Y, Yang B, Mei C, Zhang L, Chen Y
Citation:
Sci Adv. 2019:5(6):eaaw3593 doi:10.1126/sciadv.aaw3593
Epub:
Not Epub
Abstract:
Positive transcription elongation factor b (P-TEFb) functions as a central regulator of transcription elongation. Activation of...
Link:
https://advances.sciencemag.org/content/5/6/eaaw3593
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Sun Y, Liu Z, Cao X, Lu Y, Mi Z, He C, Liu J, Zheng Z, Li MJ, Li T, Xu D, Wu M, Cao Y, Li Y, Yang B, Mei C, Zhang L, Chen Y. Activation of P-TEFb by cAMP-PKA signaling in autosomal dominant polycystic kidney disease. Sci Adv. 2019:5(6):eaaw3593 doi:10.1126/sciadv.aaw3593.

Endodermal Maternal Transcription Factors Establish Super-Enhancers during Zygotic Genome Activation

Authors:
Paraiso KD, Blitz IL, Coley M, Cheung J, Sudou N, Taira M, Cho KWY
Citation:
Cell Rep. 2019;27(10):2962-77. doi:10.1016/j.celrep.2019.05.013
Epub:
Not Epub
Abstract:
Elucidation of the sequence of events underlying the dynamic interaction between transcription factors and chromatin states is...
Link:
https://www.cell.com/cell-reports/fulltext/S2211-1247(19)30624-2
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus tropicalis
Citation Extract:
Paraiso KD, Blitz IL, Coley M, Cheung J, Sudou N, Taira M, Cho KWY. Endodermal Maternal Transcription Factors Establish Super-Enhancers during Zygotic Genome Activation. Cell Rep. 2019;27(10):2962-77. doi:10.1016/j.celrep.2019.05.013.

Proteolytic and Opportunistic Breaching of the Basement Membrane Zone by Immune Cells during Tumor Initiation

Authors:
van den Berg MCW, MacCarthy-Morrogh L, Carter D, Morris J, Bravo IR, Feng Y, Martin P
Citation:
Cell Rep. 2019;27:2837-46. doi:10.1016/j.celrep.2019.05.029
Epub:
Not Epub
Abstract:
Cancer-related inflammation impacts significantly on cancer development and progression. From early stages, neutrophils and...
Link:
https://www.cell.com/cell-reports/fulltext/S2211-1247(19)30640-0
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
van den Berg MCW, MacCarthy-Morrogh L, Carter D, Morris J, Bravo IR, Feng Y, Martin P. Proteolytic and Opportunistic Breaching of the Basement Membrane Zone by Immune Cells during Tumor Initiation. Cell Rep. 2019;27:2837-46. doi:10.1016/j.celrep.2019.05.029.

Atypical Chemokine Receptor 3 Generates Guidance Cues for CXCL12-Mediated Endothelial Cell Migration

Authors:
Tobia C, Chiodelli P, Barbieri A, Buraschi S, Ferrari E, Mitola S, Borsani G, Guerra J, Presta M
Citation:
Front Immunol. 2019 May 15;10:1092. doi: 10.3389/fimmu.2019.01092. eCollection 2019
Epub:
Not Epub
Abstract:
Chemokine receptor CXCR4, its ligand stromal cell-derived factor-1 (CXCL12) and the decoy receptor atypical chemokine receptor...
Link:
https://www.frontiersin.org/articles/10.3389/fimmu.2019.01092/full
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Tobia C, Chiodelli P, Barbieri A, Buraschi S, Ferrari E, Mitola S, Borsani G, Guerra J, Presta M. Atypical Chemokine Receptor 3 Generates Guidance Cues for CXCL12-Mediated Endothelial Cell Migration. Front Immunol. 2019 May 15;10:1092. doi: 10.3389/fimmu.2019.01092. eCollection 2019.

RAB35 depletion affects spindle formation and actin-based spindle migration in mouse oocyte meiosis

Authors:
Zhang Y, Wan X, Wang HH, Pan MH, Pan ZN, Sun SC
Citation:
Mol Hum Reprod. 2019 Jun 1. pii: gaz027. doi: 10.1093/molehr/gaz027. [Epub ahead of print]
Epub:
Yes
Abstract:
Mammalian oocyte maturation involves a unique asymmetric cell division, in which meiotic spindle formation and actin filament-...
Link:
https://academic.oup.com/molehr/advance-article-abstract/doi/10.1093/molehr/gaz027/5506450
Delivery Method:
microinjection
Organism or Cell Type:
mouse oocyte
Citation Extract:
Zhang Y, Wan X, Wang HH, Pan MH, Pan ZN, Sun SC. RAB35 depletion affects spindle formation and actin-based spindle migration in mouse oocyte meiosis. Mol Hum Reprod. 2019 Jun 1. pii: gaz027. doi: 10.1093/molehr/gaz027. [Epub ahead of print].

A conserved regulatory program drives emergence of the lateral plate mesoderm

Authors:
Prummel KD, Hess C, Nieuwenhuize S, Parker HJ, Rogers KW, Kozmikova I, Racioppi C, Brombacher EC, Czarkwiani A, Knapp D, Burger S, Chiavacci E, Shah G, Burger A, Huisken J, Yun MH, Christiaen L, Kozmik Z, Müller P, Bronner M, Krumlauf R, Mosimann C
Citation:
bioRxiv. 2019;261115:[preprint] doi:10.1101/261115
Epub:
Not Epub
Abstract:
Cardiovascular lineages develop together with kidney, smooth muscle, and limb connective tissue progenitors from the lateral...
Link:
https://www.biorxiv.org/content/10.1101/261115v2.full
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Prummel KD, Hess C, Nieuwenhuize S, Parker HJ, Rogers KW, Kozmikova I, Racioppi C, Brombacher EC, Czarkwiani A, Knapp D, Burger S, Chiavacci E, Shah G, Burger A, Huisken J, Yun MH, Christiaen L, Kozmik Z, Müller P, Bronner M, Krumlauf R, Mosimann C. A conserved regulatory program drives emergence of the lateral plate mesoderm. bioRxiv. 2019;261115:[preprint] doi:10.1101/261115 .

Dual Role of Jam3b in Early Hematopoietic and Vascular Development

Authors:
Kobayashi I, Kobayashi-Sun J, Hirakawa Y, Ouchi M, Yasuda K, Kamei H, Fukuhara S, Yamaguchi M
Citation:
bioRxiv. 2019;656108:[preprint] doi:10.1101/656108
Epub:
Not Epub
Abstract:
In order to efficiently derive hematopoietic stem cells (HSCs) from pluripotent precursors, it is crucial to understand how...
Link:
https://www.biorxiv.org/content/10.1101/656108v1.full
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kobayashi I, Kobayashi-Sun J, Hirakawa Y, Ouchi M, Yasuda K, Kamei H, Fukuhara S, Yamaguchi M. Dual Role of Jam3b in Early Hematopoietic and Vascular Development. bioRxiv. 2019;656108:[preprint] doi:10.1101/656108.

Endocardial differentiation in zebrafish occurs during early somitogenesis and is dependent on BMP and etv2 signalling

Authors:
Capon SJ, Smith KA
Citation:
bioRxiv. 2019;654525:[preprint] doi:10.1101/654525
Epub:
Not Epub
Abstract:
The endocardium and adjacent vascular endothelial network share a number of molecular markers however there are distinct...
Link:
https://www.biorxiv.org/content/10.1101/654525v1.full
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Capon SJ, Smith KA. Endocardial differentiation in zebrafish occurs during early somitogenesis and is dependent on BMP and etv2 signalling. bioRxiv. 2019;654525:[preprint] doi:10.1101/654525 .

Neuromesodermal progenitors separate the axial stem zones while producing few single- and dual-fated descendants

Authors:
Wood TR, Kyrsting A, Stegmaier J, Kucinski I, Kaminski CF, Mikut R, Voiculescu O
Citation:
bioRxiv. 2019;622571:[preprint] doi:10.1101/622571
Epub:
Not Epub
Abstract:
Most embryos and regenerating tissues grow by the action of stem zones. Two epithelial stem zones drive axial elongation in...
Link:
https://www.biorxiv.org/content/10.1101/622571v2.full
Delivery Method:
electroporation
Organism or Cell Type:
Gallus gallus (chick)
Citation Extract:
Wood TR, Kyrsting A, Stegmaier J, Kucinski I, Kaminski CF, Mikut R, Voiculescu O. Neuromesodermal progenitors separate the axial stem zones while producing few single- and dual-fated descendants. bioRxiv. 2019;622571:[preprint] doi:10.1101/622571 .

Possible cooption of a VEGF-driven tubulogenesis program for biomineralization in echinoderms

Authors:
Morgulis M, Gildor T, Roopin M, Sher N, Malik A, Lalzar M, Dines M, Ben-Tabou de-Leon S, Khalaily L, Ben-Tabou de-Leon S
Citation:
Proc Natl Acad Sci USA. 2019;[Epub aheasd of print] doi:10.1073/pnas.1902126116
Epub:
Yes
Abstract:
Biomineralization is the process by which living organisms use minerals to form hard structures that protect and support them....
Link:
https://www.pnas.org/content/early/2019/05/30/1902126116
Delivery Method:
microinjection
Organism or Cell Type:
Paracentrotus lividus (sea urchin)
Citation Extract:
Morgulis M, Gildor T, Roopin M, Sher N, Malik A, Lalzar M, Dines M, Ben-Tabou de-Leon S, Khalaily L, Ben-Tabou de-Leon S. Possible cooption of a VEGF-driven tubulogenesis program for biomineralization in echinoderms. Proc Natl Acad Sci USA. 2019;[Epub aheasd of print] doi:10.1073/pnas.1902126116.

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