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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

Midgut Laterality Is Driven by Hyaluronan on the Right

Authors:
Sivakumar A, Mahadevan A, Lauer ME, Narvaez RJ, Ramesh S, Demler CM, Souchet NR, Hascall VC, Midura RJ, Garantziotis S, Frank DB, Kimata K, Kurpios NA
Citation:
Dev Cell. 2018 Aug 28. pii: S1534-5807(18)30638-5. doi: 10.1016/j.devcel.2018.08.002. [Epub ahead of print]
Epub:
Yes
Abstract:
For many years, biologists have focused on the role of Pitx2, expressed on the left side of developing embryos, in governing...
Link:
https://www.sciencedirect.com/science/article/pii/S1534580718306385
Delivery Method:
electroporation
Organism or Cell Type:
Gallus gallus (chick)
Citation Extract:
Sivakumar A, Mahadevan A, Lauer ME, Narvaez RJ, Ramesh S, Demler CM, Souchet NR, Hascall VC, Midura RJ, Garantziotis S, Frank DB, Kimata K, Kurpios NA. Midgut Laterality Is Driven by Hyaluronan on the Right. Dev Cell. 2018 Aug 28. pii: S1534-5807(18)30638-5. doi: 10.1016/j.devcel.2018.08.002. [Epub ahead of print].

PGE2 production at sites of tissue injury promotes an anti-inflammatory neutrophil phenotype and determines the outcome of inflammation resolution in vivo

Authors:
Loynes CA, Lee JA, Robertson AL, Steel MJG, Ellett F, Feng Y, Levy BD, Whyte MKB, Renshaw SA
Citation:
Sci Advances. 2018;4(9):eaar8320. doi:10.1126/sciadv.aar8320
Epub:
Not Epub
Abstract:
Neutrophils are the first immune cells recruited to a site of injury or infection, where they perform many functions. Having...
Link:
http://advances.sciencemag.org/content/4/9/eaar8320
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Loynes CA, Lee JA, Robertson AL, Steel MJG, Ellett F, Feng Y, Levy BD, Whyte MKB, Renshaw SA. PGE2 production at sites of tissue injury promotes an anti-inflammatory neutrophil phenotype and determines the outcome of inflammation resolution in vivo. Sci Advances. 2018;4(9):eaar8320. doi:10.1126/sciadv.aar8320.

Persistent Marburg Virus Infection in the Testes of Nonhuman Primate Survivors

Authors:
Coffin KM, Liu J, Warren TK, Blancett CD, Kuehl KA, Nichols DK, Bearss JJ, Schellhase CW, Retterer CJ, Weidner JM, Radoshitzky SR, Brannan JM, Cardile AP, Dye JM, Palacios G, Sun MG, Kuhn JH, Bavari S, Zeng X
Citation:
Cell Host Microbe. 2018 Sep 12;24(3):405-416.e3. doi: 10.1016/j.chom.2018.08.003. Epub 2018 Aug 30. PMID: 30173956
Epub:
Yes
Abstract:
Sexual transmission of filoviruses was first reported in 1968 after an outbreak of Marburg virus (MARV) disease and recently...
Link:
https://www.cell.com/cell-host-microbe/fulltext/S1931-3128(18)30431-1
Organism or Cell Type:
Macaca fascicularis (crab-eating macaque, cynomolgus monkey)
Citation Extract:
Coffin KM, Liu J, Warren TK, Blancett CD, Kuehl KA, Nichols DK, Bearss JJ, Schellhase CW, Retterer CJ, Weidner JM, Radoshitzky SR, Brannan JM, Cardile AP, Dye JM, Palacios G, Sun MG, Kuhn JH, Bavari S, Zeng X. Persistent Marburg Virus Infection in the Testes of Nonhuman Primate Survivors. Cell Host Microbe. 2018 Sep 12;24(3):405-416.e3. doi: 10.1016/j.chom.2018.08.003. Epub 2018 Aug 30. PMID: 30173956.

Mutations in multiple components of the nuclear pore complex cause nephrotic syndrome

Authors:
Braun DA, Lovric S, Schapiro D, Schneider R, Marquez J, Asif M, Hussain MS, Daga A, Widmeier E, Rao J, Ashraf S, Tan W, Lusk CP, Kolb A, Jobst-Schwan T, Schmidt JM, Hoogstraten CA, Eddy K, Kitzler TM, Shril S, Moawia A, Schrage K, Khayyat AIA, Lawson JA, Gee HY, Warejko JK, Hermle T, Majmundar AJ, Hugo H, Budde B, Motameny S, Altmüller J, Noegel AA, Fathy HM, Gale DP, Waseem SS, Khan A, Kerecuk L, Hashmi S, Mohebbi N, Ettenger R, Serdaroğlu E, Alhasan KA, Hashem M, Goncalves S, Ariceta G, Ubetagoyena M, Antonin W, Baig SM, Alkuraya FS, Shen Q, Xu H, Antignac C, Lifton RP, Mane S, Nürnberg P, Khokha MK, Hildebrandt F
Citation:
J Clin Invest. 2018 Sep 4. pii: 98688. doi: 10.1172/JCI98688. [Epub ahead of print]
Epub:
Yes
Abstract:
Steroid-resistant nephrotic syndrome (SRNS) almost invariably progresses to end-stage renal disease. Although more than 50...
Link:
https://jci.org/articles/view/98688
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Braun DA, Lovric S, Schapiro D, Schneider R, Marquez J, Asif M, Hussain MS, Daga A, Widmeier E, Rao J, Ashraf S, Tan W, Lusk CP, Kolb A, Jobst-Schwan T, Schmidt JM, Hoogstraten CA, Eddy K, Kitzler TM, Shril S, Moawia A, Schrage K, Khayyat AIA, Lawson JA, Gee HY, Warejko JK, Hermle T, Majmundar AJ, Hugo H, Budde B, Motameny S, Altmüller J, Noegel AA, Fathy HM, Gale DP, Waseem SS, Khan A, Kerecuk L, Hashmi S, Mohebbi N, Ettenger R, Serdaroğlu E, Alhasan KA, Hashem M, Goncalves S, Ariceta G, Ubetagoyena M, Antonin W, Baig SM, Alkuraya FS, Shen Q, Xu H, Antignac C, Lifton RP, Mane S, Nürnberg P, Khokha MK, Hildebrandt F. Mutations in multiple components of the nuclear pore complex cause nephrotic syndrome. J Clin Invest. 2018 Sep 4. pii: 98688. doi: 10.1172/JCI98688. [Epub ahead of print].

Use of Glucose-Fructose to Enhance the Exon Skipping Efficacy

Authors:
Han G, Gao X, Yin H
Citation:
Methods Mol Biol. 2018;1828:327-342. doi: 10.1007/978-1-4939-8651-4_20
Epub:
Not Epub
Abstract:
Exon-skipping antisense oligonucleotides (AOs) are promising treatments for muscle-related genetic ailments including Duchenne...
Link:
https://link.springer.com/protocol/10.1007%2F978-1-4939-8651-4_20
Delivery Method:
injection
Organism or Cell Type:
mice mdx
Citation Extract:
Han G, Gao X, Yin H. Use of Glucose-Fructose to Enhance the Exon Skipping Efficacy. Methods Mol Biol. 2018;1828:327-342. doi: 10.1007/978-1-4939-8651-4_20.

Systemic Intravenous Administration of Antisense Therapeutics for Combinatorial Dystrophin and Myostatin Exon Splice Modulation

Authors:
Lu-Nguyen N, Dickson G, Malerba A
Citation:
Methods Mol Biol. 2018;1828:343-354. doi: 10.1007/978-1-4939-8651-4_21
Epub:
Not Epub
Abstract:
Using antisense oligonucleotides (AOs) to reframe mutated dystrophin, a recently developed therapeutic approach for Duchenne...
Link:
https://link.springer.com/protocol/10.1007%2F978-1-4939-8651-4_21
Organism or Cell Type:
mice mdx
Citation Extract:
Lu-Nguyen N, Dickson G, Malerba A. Systemic Intravenous Administration of Antisense Therapeutics for Combinatorial Dystrophin and Myostatin Exon Splice Modulation. Methods Mol Biol. 2018;1828:343-354. doi: 10.1007/978-1-4939-8651-4_21.

Antisense Oligonucleotide Targeting of 3'-UTR of mRNA for Expression Knockdown

Authors:
Golshirazi G, Ciszewski L, Lu-Nguyen N, Popplewell L
Citation:
Methods Mol Biol. 2018;1828:91-124. doi: 10.1007/978-1-4939-8651-4_6
Epub:
Not Epub
Abstract:
With the recent conditional approval of an antisense oligonucleotide (AON) that restores the reading frame of DMD transcript in...
Link:
https://link.springer.com/protocol/10.1007%2F978-1-4939-8651-4_6
Citation Extract:
Golshirazi G, Ciszewski L, Lu-Nguyen N, Popplewell L. Antisense Oligonucleotide Targeting of 3'-UTR of mRNA for Expression Knockdown. Methods Mol Biol. 2018;1828:91-124. doi: 10.1007/978-1-4939-8651-4_6.

14-3-3εa directs the pulsatile transport of basal factors toward the apical domain for lumen growth in tubulogenesis

Authors:
Mizotani Y, Suzuki M, Hotta K, Watanabe H, Shiba K, Inaba K, Tashiro E, Oka K, Imoto M
Citation:
Proc Natl Acad Sci U S A. 2018 Aug 29. pii: 201808756. doi: 10.1073/pnas.1808756115. [Epub ahead of print]
Epub:
Yes
Abstract:
The Ciona notochord has emerged as a simple and tractable in vivo model for tubulogenesis. Here, using a chemical genetics...
Link:
Proc Natl Acad Sci U S A. 2018 Aug 29. pii: 201808756. doi: 10.1073/pnas.1808756115. [Epub ahead of print]
Delivery Method:
microinjection
Organism or Cell Type:
Ciona intestinalis (ascidian)
Citation Extract:
Mizotani Y, Suzuki M, Hotta K, Watanabe H, Shiba K, Inaba K, Tashiro E, Oka K, Imoto M. 14-3-3εa directs the pulsatile transport of basal factors toward the apical domain for lumen growth in tubulogenesis. Proc Natl Acad Sci U S A. 2018 Aug 29. pii: 201808756. doi: 10.1073/pnas.1808756115. [Epub ahead of print].

Dnd is required for primordial germ cell specification in Oryzias celebensis

Authors:
Zhu T, Gui L, Zhu Y, Li Y, Li M
Citation:
Gene. 2018 Aug 29. pii: S0378-1119(18)30928-4. doi: 10.1016/j.gene.2018.08.068. [Epub ahead of print]
Epub:
Yes
Abstract:
Dead end (dnd) is a germ plasm component that plays an essential role for primordial germ cell (PGC) development in vertebrates...
Link:
https://www.sciencedirect.com/science/article/pii/S0378111918309284?via%3Dihub
Delivery Method:
microinjection
Organism or Cell Type:
Oryzias celebensis (Celebes ricefish)
Citation Extract:
Zhu T, Gui L, Zhu Y, Li Y, Li M. Dnd is required for primordial germ cell specification in Oryzias celebensis. Gene. 2018 Aug 29. pii: S0378-1119(18)30928-4. doi: 10.1016/j.gene.2018.08.068. [Epub ahead of print].

Exon Skipping Using Antisense Oligonucleotides for Laminin-Alpha2-Deficient Muscular Dystrophy

Authors:
Hara Y, Mizobe Y, Miyatake S, Takizawa H, Nagata T, Yokota T, Takeda S, Aoki Y
Citation:
Methods Mol Biol. 2018;1828:553-564. doi: 10.1007/978-1-4939-8651-4_36
Epub:
Not Epub
Abstract:
Phosphorodiamidate morpholino oligomer (PMO)-mediated exon skipping is among the more promising approaches available for the...
Link:
https://link.springer.com/protocol/10.1007%2F978-1-4939-8651-4_36
Organism or Cell Type:
mice laminin-α2-deficient dy 3K/dy 3K
Citation Extract:
Hara Y, Mizobe Y, Miyatake S, Takizawa H, Nagata T, Yokota T, Takeda S, Aoki Y. Exon Skipping Using Antisense Oligonucleotides for Laminin-Alpha2-Deficient Muscular Dystrophy. Methods Mol Biol. 2018;1828:553-564. doi: 10.1007/978-1-4939-8651-4_36.

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