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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

Inactivation of AMMECR1 is associated with growth, bone and heart alterations

Authors:
Moysés-Oliveira M, Giannuzzi G, Fish RJ, Rosenfeld JA, Petit F, de Fatima Soares M, Kulikowski LD, Battista AD, Zamariolli M, Xia F, Liehr T, Kosyakova N, Carvalheira G, Parker M, Seaby EG, Ennis S, Gilbert RD, Hagelstrom RT, Cremona ML, Li WL, Malhotra A, Chandrasekhar A, Perry DL, Taft RJ, McCarrier J, Basel DG, Andrieux J, Stumpp T, Antunes F, Pereira GJ, Neerman-Arbez M, Meloni VA, Drummond-Borg M, Melaragno MI, Reymond A
Citation:
Hum Mutat. 2017 Nov 28. doi: 10.1002/humu.23373. [Epub ahead of print]
Epub:
Not Epub
Abstract:
We report five individuals with loss-of-function of the X-linked AMMECR1: a girl with a balanced X-autosome translocation and...
Link:
http://onlinelibrary.wiley.com/doi/10.1002/humu.23373/abstract
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Moysés-Oliveira M, Giannuzzi G, Fish RJ, Rosenfeld JA, Petit F, de Fatima Soares M, Kulikowski LD, Battista AD, Zamariolli M, Xia F, Liehr T, Kosyakova N, Carvalheira G, Parker M, Seaby EG, Ennis S, Gilbert RD, Hagelstrom RT, Cremona ML, Li WL, Malhotra A, Chandrasekhar A, Perry DL, Taft RJ, McCarrier J, Basel DG, Andrieux J, Stumpp T, Antunes F, Pereira GJ, Neerman-Arbez M, Meloni VA, Drummond-Borg M, Melaragno MI, Reymond A. Inactivation of AMMECR1 is associated with growth, bone and heart alterations. Hum Mutat. 2017 Nov 28. doi: 10.1002/humu.23373. [Epub ahead of print].

The ectodomain of cadherin-11 binds to erbB2 and stimulates Akt phosphorylation to promote cranial neural crest cell migration

Authors:
Mathavan K, Khedgikar V, Bartolo V, Alfandari D
Citation:
PLoS ONE. 2017;12(11): e0188963. doi:10.1371/journal.pone.0188963
Epub:
Not Epub
Abstract:
During development, a multi-potent group of cells known as the cranial neural crest (CNC) migrate to form craniofacial...
Link:
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0188963
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Mathavan K, Khedgikar V, Bartolo V, Alfandari D. The ectodomain of cadherin-11 binds to erbB2 and stimulates Akt phosphorylation to promote cranial neural crest cell migration. PLoS ONE. 2017;12(11): e0188963. doi:10.1371/journal.pone.0188963.

Vesicular transport protein Arf6 modulates cytoskeleton dynamics for polar body extrusion in mouse oocyte meiosis

Authors:
Duan X, Zhang HL, Pan MH, Zhang Y, Sun SC
Citation:
Biochim Biophys Acta. 2017 Dec 2. pii: S0167-4889(17)30315-4. doi: 10.1016/j.bbamcr.2017.11.016. [Epub ahead of print]
Epub:
Yes
Abstract:
Arf6 (ADP-ribosylation factor 6) is known to play important roles in membrane dynamics through the regulation of actin filament...
Link:
http://www.sciencedirect.com/science/article/pii/S0167488917303154
Delivery Method:
microinjection
Organism or Cell Type:
mouse oocyte
Citation Extract:
Duan X, Zhang HL, Pan MH, Zhang Y, Sun SC. Vesicular transport protein Arf6 modulates cytoskeleton dynamics for polar body extrusion in mouse oocyte meiosis. Biochim Biophys Acta. 2017 Dec 2. pii: S0167-4889(17)30315-4. doi: 10.1016/j.bbamcr.2017.11.016. [Epub ahead of print].

Targeting erythropoietin protects against proteinuria in type 2 diabetic patients and in zebrafish

Authors:
She J, Yuan Z, Wu Y, Chen J, Kroll J
Citation:
Mol Metab. 2017 Nov 22. pii: S2212-8778(17)30877-3. doi: 10.1016/j.molmet.2017.11.006. [Epub ahead of print]
Epub:
Yes
Abstract:
OBJECTIVE: Adult human kidneys produce erythropoietin (EPO), which regulates red blood cell formation; however, whether EPO...
Link:
http://www.molmetab.com/article/S2212-8778(17)30877-3/abstract
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
She J, Yuan Z, Wu Y, Chen J, Kroll J. Targeting erythropoietin protects against proteinuria in type 2 diabetic patients and in zebrafish. Mol Metab. 2017 Nov 22. pii: S2212-8778(17)30877-3. doi: 10.1016/j.molmet.2017.11.006. [Epub ahead of print].

Functional roles of agmatinase during the peri-implantation period of pregnancy in sheep

Authors:
Lenis YY, Elmetwally MA, Tang W, Satterfield C, Dunlap K, Wu G, Bazer FW
Citation:
Amino Acids. 2017 Dec 2. doi: 10.1007/s00726-017-2515-1. [Epub ahead of print]
Epub:
Yes
Abstract:
This study investigated the effect of agmatine (Agm) in proliferation of ovine trophecdoderm cells (oTr1) as well as the...
Link:
https://link.springer.com/article/10.1007%2Fs00726-017-2515-1
Organism or Cell Type:
Ovis aries (sheep)
Citation Extract:
Lenis YY, Elmetwally MA, Tang W, Satterfield C, Dunlap K, Wu G, Bazer FW. Functional roles of agmatinase during the peri-implantation period of pregnancy in sheep. Amino Acids. 2017 Dec 2. doi: 10.1007/s00726-017-2515-1. [Epub ahead of print].

Transcriptomics reveal an integrative role for maternal thyroid hormones during zebrafish embryogenesis

Authors:
Silva N, Louro B, Trindade M, Power DM, Campinho MA
Citation:
Sci Rep. 2017;7:16657. doi:10.1038/s41598-017-16951-9
Epub:
Not Epub
Abstract:
Thyroid hormones (THs) are essential for embryonic brain development but the genetic mechanisms involved in the action of...
Link:
https://www.nature.com/articles/s41598-017-16951-9
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Silva N, Louro B, Trindade M, Power DM, Campinho MA. Transcriptomics reveal an integrative role for maternal thyroid hormones during zebrafish embryogenesis. Sci Rep. 2017;7:16657. doi:10.1038/s41598-017-16951-9.

Inhibition of Delta-induced Notch signaling using fucose analogs

Authors:
Schneider M, Kumar V, Nordstrøm LU, Feng L, Takeuchi H, Hao H, Luca VC, Garcia KC, Stanley P, Wu P, Haltiwanger RS
Citation:
Nat Chem Biol. 2017 Nov 27. doi: 10.1038/nchembio.2520. [Epub ahead of print]
Epub:
Yes
Abstract:
Notch is a cell-surface receptor that controls cell-fate decisions and is regulated by O-glycans attached to epidermal growth...
Link:
https://www.nature.com/articles/nchembio.2520
Organism or Cell Type:
zebrafish
Citation Extract:
Schneider M, Kumar V, Nordstrøm LU, Feng L, Takeuchi H, Hao H, Luca VC, Garcia KC, Stanley P, Wu P, Haltiwanger RS. Inhibition of Delta-induced Notch signaling using fucose analogs. Nat Chem Biol. 2017 Nov 27. doi: 10.1038/nchembio.2520. [Epub ahead of print].

Accurate quantification of homologous recombination in zebrafish: brca2 deficiency as a paradigm

Authors:
Vierstraete J, Willaert A, Vermassen P, Coucke PJ, Vral A, Claes KBM
Citation:
Sci Rep. 2017;7:16518. doi:10.1038/s41598-017-16725-3
Epub:
Not Epub
Abstract:
Homologous Recombination (HR) repair is essential for repairing DNA double strand breaks (DSB) in dividing cells and preventing...
Link:
https://www.nature.com/articles/s41598-017-16725-3
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Vierstraete J, Willaert A, Vermassen P, Coucke PJ, Vral A, Claes KBM. Accurate quantification of homologous recombination in zebrafish: brca2 deficiency as a paradigm. Sci Rep. 2017;7:16518. doi:10.1038/s41598-017-16725-3.

Role of WNT10A in failure of tooth development in humans and zebrafish

Authors:
Yuan Q, Zhao M, Tandon B, Maili L, Liu X, Zhang A, Baugh EH, Tran T, Silva RM, Hecht JT, Swindell EC, Wagner DS, Letra A
Citation:
Mol Genet Genomic Med. 2017 Nov;5(6):730-741. doi: 10.1002/mgg3.332. Epub 2017 Sep 14
Epub:
Not Epub
Abstract:
BACKGROUND: Oligodontia is a severe form of tooth agenesis characterized by the absence of six or more permanent teeth....
Link:
http://onlinelibrary.wiley.com/doi/10.1002/mgg3.332/abstract
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Yuan Q, Zhao M, Tandon B, Maili L, Liu X, Zhang A, Baugh EH, Tran T, Silva RM, Hecht JT, Swindell EC, Wagner DS, Letra A. Role of WNT10A in failure of tooth development in humans and zebrafish. Mol Genet Genomic Med. 2017 Nov;5(6):730-741. doi: 10.1002/mgg3.332. Epub 2017 Sep 14.

Acetylation of TBX5 by KAT2B and KAT2A regulates heart and limb development

Authors:
Ghosh TK, Aparicio-Sánchez JJ, Buxton S, Ketley A, Mohamed T, Rutland CS, Loughna S, Brook JD
Citation:
J Mol Cell Cardiol. 2017 Nov 22. pii: S0022-2828(17)30348-6. doi: 10.1016/j.yjmcc.2017.11.013. [Epub ahead of print]
Epub:
Yes
Abstract:
TBX5 plays a critical role in heart and forelimb development. Mutations in TBX5 cause Holt-Oram syndrome, an autosomal dominant...
Link:
http://www.jmmc-online.com/article/S0022-2828(17)30348-6/fulltext
Organism or Cell Type:
zebrafish
Citation Extract:
Ghosh TK, Aparicio-Sánchez JJ, Buxton S, Ketley A, Mohamed T, Rutland CS, Loughna S, Brook JD. Acetylation of TBX5 by KAT2B and KAT2A regulates heart and limb development. J Mol Cell Cardiol. 2017 Nov 22. pii: S0022-2828(17)30348-6. doi: 10.1016/j.yjmcc.2017.11.013. [Epub ahead of print].

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