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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12419 scientific papers returned from the database with the search filters currently being used below.
There are 12419 scientific papers returned from the database with the search filters currently being used below.
Development of the aboral domain in Nematostella requires β-catenin and the opposing activities of Six3/6 and Frizzled5/8
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Citation:
Development. 2016;143:1766-1777. doi: 10.1242/dev.120931 Epub:
Not Epub Abstract:
The development of the oral pole in cnidarians and the posterior pole in bilaterians is regulated by canonical Wnt signaling,... Delivery Method:
microinjection Organism or Cell Type:
Nematostella vectensis (sea anemone) Citation Extract: Leclère L, Bause M, Sinigaglia C, Steger J, Rentzsch F. Development of the aboral domain in Nematostella requires β-catenin and the opposing activities of Six3/6 and Frizzled5/8. Development. 2016;143:1766-1777. doi: 10.1242/dev.120931 . |
klf2a couples mechanotransduction and zebrafish valve morphogenesis through fibronectin synthesis
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Citation:
Nat Comm. 2016;7:11646. doi:10.1038/ncomms11646 Epub:
Not Epub Abstract:
The heartbeat and blood flow signal to endocardial cell progenitors through mechanosensitive proteins that modulate the genetic... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Steed E, Faggianelli N, Roth S, Ramspacher C, Concordet J-P, Vermot J. klf2a couples mechanotransduction and zebrafish valve morphogenesis through fibronectin synthesis. Nat Comm. 2016;7:11646. doi:10.1038/ncomms11646. |
The polycystin complex mediates Wnt/Ca2+ signalling
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Citation:
Nat Cell Biol. 2016 May 23. doi: 10.1038/ncb3363. [Epub ahead of print] Epub:
Yes Abstract:
WNT ligands induce Ca2+ signalling on target cells. PKD1 (polycystin 1) is considered an orphan, atypical G-protein-coupled... Delivery Method:
microinjection Organism or Cell Type:
Xenopus Citation Extract: Kim S, Nie H, Nesin V, Tran U, Outeda P, Bai CX, Keeling J, Maskey D, Watnick T, Wessely O, Tsiokas L. The polycystin complex mediates Wnt/Ca2+ signalling. Nat Cell Biol. 2016 May 23. doi: 10.1038/ncb3363. [Epub ahead of print]. |
Open and closed evolutionary paths for drastic morphological changes, involving serial gene duplication, sub-functionalization, and selection
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Citation:
Sci Rep. 2016;6:26838. doi:10.1038/srep26838 Epub:
Not Epub Abstract:
Twin-tail goldfish strains are examples of drastic morphological alterations that emerged through domestication. Although this... Delivery Method:
microinjection Organism or Cell Type:
Carassius auratus (goldfish), Cyprinus carpio (common carp) Citation Extract: Abe G, Lee S-H, Li I-J, Chang C-J, Tamura K,Ota KG. Open and closed evolutionary paths for drastic morphological changes, involving serial gene duplication, sub-functionalization, and selection. Sci Rep. 2016;6:26838. doi:10.1038/srep26838. |
NANS-mediated synthesis of sialic acid is required for brain and skeletal development
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Citation:
Nat Genet. 2016 May 23. doi: 10.1038/ng.3578. [Epub ahead of print] Epub:
Yes Abstract:
We identified biallelic mutations in NANS, the gene encoding the synthase for N-acetylneuraminic acid (NeuNAc; sialic acid), in... Organism or Cell Type:
zebrafish Citation Extract: van Karnebeek CD, Bonafé L, Wen XY, Tarailo-Graovac M, Balzano S, Royer-Bertrand B, Ashikov A, Garavelli L, Mammi I, Turolla L, Breen C, Donnai D, Cormier V, Heron D, Nishimura G, Uchikawa S, Campos-Xavier B, Rossi A, Hennet T, Brand-Arzamendi K, Rozmus J, Harshman K, Stevenson BJ, Girardi E, Superti-Furga G, Dewan T, Collingridge A, Halparin J, Ross CJ, Van Allen MI, Rossi A, Engelke UF, Kluijtmans LA, van der Heeft E, Renkema H, de Brouwer A, Huijben K, Zijlstra F, Heisse T, Boltje T, Wasserman WW, Rivolta C, Unger S, Lefeber DJ, Wevers RA, Superti-Furga A. NANS-mediated synthesis of sialic acid is required for brain and skeletal development. Nat Genet. 2016 May 23. doi: 10.1038/ng.3578. [Epub ahead of print]. |
Developmental suppression of schizophrenia-associated miR-137 alters sensorimotor function in zebrafish
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Citation:
Transl Psychiatry. 2016 May 24;6:e818. doi: 10.1038/tp.2016.88 Epub:
Not Epub Abstract:
The neurodevelopmentally regulated microRNA miR-137 was strongly implicated as risk locus for schizophrenia in the most recent... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Giacomotto J, Carroll AP, Rinkwitz S, Mowry B, Cairns MJ, Becker TS. Developmental suppression of schizophrenia-associated miR-137 alters sensorimotor function in zebrafish. Transl Psychiatry. 2016 May 24;6:e818. doi: 10.1038/tp.2016.88. |
The cardiac-restricted protein ADP-ribosylhydrolase-like 1 is essential for heart chamber outgrowth and acts on muscle actin filament assembly
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Citation:
Dev Biol. 2016 May 20. pii: S0012-1606(15)30138-X. doi: 10.1016/j.ydbio.2016.05.006. [Epub ahead of print] Epub:
Yes Abstract:
Adprhl1, a member of the ADP-ribosylhydrolase protein family, is expressed exclusively in the developing heart of all... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Smith SJ, Towers N, Saldanha JW, Shang CA, Mahmood SR, Taylor WR, Mohun TJ. The cardiac-restricted protein ADP-ribosylhydrolase-like 1 is essential for heart chamber outgrowth and acts on muscle actin filament assembly. Dev Biol. 2016 May 20. pii: S0012-1606(15)30138-X. doi: 10.1016/j.ydbio.2016.05.006. [Epub ahead of print]. |
Embryonic cardiotoxicity of weak aryl hydrocarbon receptor agonists and cyp1a inhibitor fluoranthene in the Atlantic killifish (Fundulus heteroclitus)
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Citation:
Comp Biochem Physiol C Toxicol Pharmacol. 2016 May 20. pii: S1532-0456(16)30062-X. doi: 10.1016/j.cbpc.2016.05.005. [Epub ahead of print] Epub:
Not Epub Abstract:
High affinity aryl hydrocarbon receptor (AHR) ligands, such as certain polychlorinated biphenyls and 2,3,7,8-tetrachlorodibenzo... Delivery Method:
microinjection Organism or Cell Type:
Fundulus heteroclitus (killifish) Citation Extract: Brown DR, Clark BW, Garner LV, Di Giulio RT. Embryonic cardiotoxicity of weak aryl hydrocarbon receptor agonists and cyp1a inhibitor fluoranthene in the Atlantic killifish (Fundulus heteroclitus). Comp Biochem Physiol C Toxicol Pharmacol. 2016 May 20. pii: S1532-0456(16)30062-X. doi: 10.1016/j.cbpc.2016.05.005. [Epub ahead of print]. |
Macrophage development from HSCs requires PU.1-coordinated microRNA expression
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Citation:
Blood. 2011 Aug 25;118(8):2275-84. doi: 10.1182/blood-2011-02-335141. Epub 2011 Jul 5 Epub:
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The differentiation of HSCs into myeloid lineages requires the transcription factor PU.1. Whereas PU.1-dependent induction of... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Ghani S, Riemke P, Schönheit J, Lenze D, Stumm J, Hoogenkamp M, Lagendijk A, Heinz S, Bonifer C, Bakkers J, Abdelilah-Seyfried S, Hummel M, Rosenbauer F. Macrophage development from HSCs requires PU.1-coordinated microRNA expression. Blood. 2011 Aug 25;118(8):2275-84. doi: 10.1182/blood-2011-02-335141. Epub 2011 Jul 5. |
Identification of new regulators of embryonic patterning and morphogenesis in Xenopus gastrulae by RNA sequencing
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Citation:
Dev Biol. 2016 May 18. pii: S0012-1606(16)30125-7. doi: 10.1016/j.ydbio.2016.05.014. [Epub ahead of print] Epub:
Yes Abstract:
During early vertebrate embryogenesis, cell fate specification is often coupled with cell acquisition of specific adhesive,... Organism or Cell Type:
Xenopus Citation Extract: Popov IK, Kwon T, Crossman DK, Crowley MR, Wallingford JB, Chang C. Identification of new regulators of embryonic patterning and morphogenesis in Xenopus gastrulae by RNA sequencing. Dev Biol. 2016 May 18. pii: S0012-1606(16)30125-7. doi: 10.1016/j.ydbio.2016.05.014. [Epub ahead of print]. |