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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12184 scientific papers returned from the database with the search filters currently being used below.

Phages as immunomodulators and their promising use as anti-inflammatory agents in a cftr loss-of-function zebrafish model

Authors:
Cafora M, Brix A, Forti F, Loberto N, Aureli M, Briani F, Pistocchi A
Citation:
J Cyst Fibros. 2020;[Epub ahead of print] doi:10.1016/j.jcf.2020.11.017
Epub:
Yes
Abstract:
Cystic Fibrosis (CF), one of the most frequent hereditary diseases due to mutations in the CFTR gene, causes mortality in...
Link:
https://www.cysticfibrosisjournal.com/article/S1569-1993(20)30927-9/pdf
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Cafora M, Brix A, Forti F, Loberto N, Aureli M, Briani F, Pistocchi A. Phages as immunomodulators and their promising use as anti-inflammatory agents in a cftr loss-of-function zebrafish model. J Cyst Fibros. 2020;[Epub ahead of print] doi:10.1016/j.jcf.2020.11.017.

Using migrating cells as probes to illuminate features in live embryonic tissues

Authors:
Gross-Thebing S, Truszkowski L, Tenbrinck D, Sánchez-Iranzo H, Camelo C, Westerich KJ, Singh A, Maier P, Prengel J, Lange P, Hüwel J, Gaede F, Sasse R, Vos BE, Betz T, Matis M, Prevedel R, Luschnig S, Diz-Muñoz A, Burger M, Raz E
Citation:
Sci Adv. 2020 Dec 4;6(49):eabc5546. doi: 10.1126/sciadv.abc5546. Print 2020 Dec
Epub:
Yes
Abstract:
The biophysical and biochemical properties of live tissues are important in the context of development and disease. Methods for...
Link:
https://advances.sciencemag.org/content/6/49/eabc5546
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Gross-Thebing S, Truszkowski L, Tenbrinck D, Sánchez-Iranzo H, Camelo C, Westerich KJ, Singh A, Maier P, Prengel J, Lange P, Hüwel J, Gaede F, Sasse R, Vos BE, Betz T, Matis M, Prevedel R, Luschnig S, Diz-Muñoz A, Burger M, Raz E. Using migrating cells as probes to illuminate features in live embryonic tissues. Sci Adv. 2020 Dec 4;6(49):eabc5546. doi: 10.1126/sciadv.abc5546. Print 2020 Dec.

Long noncoding RNAs implicated in embryonic development in Ybx1 knockout zebrafish

Authors:
Huang C, Zhu B, Leng D, Ge W, Zhang XD
Citation:
FEBS Open Bio. 2021 Apr;11(4):1259-1276. doi: 10.1002/2211-5463.13057
Epub:
Not Epub
Abstract:
Y-box-binding protein 1 (Ybx1, YB-1), also known as Y-box transcription factor, is involved in a variety of biological...
Link:
https://febs.onlinelibrary.wiley.com/doi/10.1002/2211-5463.13057
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Huang C, Zhu B, Leng D, Ge W, Zhang XD. Long noncoding RNAs implicated in embryonic development in Ybx1 knockout zebrafish. FEBS Open Bio. 2021 Apr;11(4):1259-1276. doi: 10.1002/2211-5463.13057.

Systematic comparison of sea urchin and sea star developmental gene regulatory networks explains how novelty is incorporated in early development

Authors:
Cary GA, McCauley BS, Zueva O, Pattinato J, Longabaugh W, Hinman VF
Citation:
Nat Commun. 2020;11:6235. doi:10.1038/s41467-020-20023-4
Epub:
Not Epub
Abstract:
The extensive array of morphological diversity among animal taxa represents the product of millions of years of evolution....
Link:
https://www.nature.com/articles/s41467-020-20023-4
Delivery Method:
microinjection
Organism or Cell Type:
Patiria miniata (sea star)
Citation Extract:
Cary GA, McCauley BS, Zueva O, Pattinato J, Longabaugh W, Hinman VF. Systematic comparison of sea urchin and sea star developmental gene regulatory networks explains how novelty is incorporated in early development. Nat Commun. 2020;11:6235. doi:10.1038/s41467-020-20023-4.

Peptide-Conjugated Phosphorodiamidate Morpholino Oligomers for In Situ Live-Cell Molecular Imaging of Dengue Virus Replication

Authors:
Victorio CB, Novera W, Tham JY, Watanabe S, Vasudevan SG, Chacko A-M
Citation:
Int J Molec Sci. 2020;21(23):1422-0067 doi:10.3390/ijms21239260
Epub:
Not Epub
Abstract:
Current methods to detect and monitor pathogens in biological systems are largely limited by the tradeoffs between spatial...
Link:
https://www.mdpi.com/1422-0067/21/23/9260
Delivery Method:
peptide-linked
Organism or Cell Type:
cell culture: Vero, BHK-21
Citation Extract:
Victorio CB, Novera W, Tham JY, Watanabe S, Vasudevan SG, Chacko A-M. Peptide-Conjugated Phosphorodiamidate Morpholino Oligomers for In Situ Live-Cell Molecular Imaging of Dengue Virus Replication. Int J Molec Sci. 2020;21(23):1422-0067 doi:10.3390/ijms21239260.

The N-glycome regulates the endothelial-to-hematopoietic transition

Authors:
Kasper DM, Hintzen J, Wu Y, Ghersi JJ, Mandl HK, Salinas KE, Armero W, He Z, Sheng Y, Xie Y, Heindel DW, Park EJ, William C. Sessa WC, Mahal LK, Lebrilla C, Hirschi KK, Nicoli S
Citation:
Science. 2020:370(6521):1186-1191. doi:10.1126/science.aaz2121
Epub:
Not Epub
Abstract:
Definitive hematopoietic stem and progenitor cells (HSPCs) arise from the transdifferentiation of hemogenic endothelial cells (...
Link:
https://science.sciencemag.org/content/370/6521/1186
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kasper DM, Hintzen J, Wu Y, Ghersi JJ, Mandl HK, Salinas KE, Armero W, He Z, Sheng Y, Xie Y, Heindel DW, Park EJ, William C. Sessa WC, Mahal LK, Lebrilla C, Hirschi KK, Nicoli S. The N-glycome regulates the endothelial-to-hematopoietic transition. Science. 2020:370(6521):1186-1191. doi:10.1126/science.aaz2121.

Unravelling the developmental and functional significance of an ancient Argonaute duplication

Authors:
Fridrich A, Modepalli V, Lewandowska M, Aharoni R, Moran Y
Citation:
Nat Comm. 2020;11:6187. doi:10.1038/s41467-020-20003-8
Epub:
Not Epub
Abstract:
MicroRNAs (miRNAs) base-pair to messenger RNA targets and guide Argonaute proteins to mediate their silencing. This target...
Link:
https://www.nature.com/articles/s41467-020-20003-8
Organism or Cell Type:
Nematostella vectensis (cniderian)
Citation Extract:
Fridrich A, Modepalli V, Lewandowska M, Aharoni R, Moran Y. Unravelling the developmental and functional significance of an ancient Argonaute duplication. Nat Comm. 2020;11:6187. doi:10.1038/s41467-020-20003-8.

Pax9 is essential for granulopoiesis but dispensable for erythropoiesis in zebrafish

Authors:
Pak B, Schmitt CE, Oh S, Kim JD, Choi W, Han O, Kim M, Kim MJ, Ham HJ, Kim S, Huh TL, Kim JI, Jin SW
Citation:
Biochem Biophys Res Commun. 2020 Nov 27:S0006-291X(20)32121-5. doi: 10.1016/j.bbrc.2020.11.077. Online ahead of print
Epub:
Yes
Abstract:
Paired Box (Pax) gene family, a group of transcription regulators have been implicated in diverse physiological processes....
Link:
https://www.sciencedirect.com/science/article/pii/S0006291X20321215
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Pak B, Schmitt CE, Oh S, Kim JD, Choi W, Han O, Kim M, Kim MJ, Ham HJ, Kim S, Huh TL, Kim JI, Jin SW. Pax9 is essential for granulopoiesis but dispensable for erythropoiesis in zebrafish. Biochem Biophys Res Commun. 2020 Nov 27:S0006-291X(20)32121-5. doi: 10.1016/j.bbrc.2020.11.077. Online ahead of print.

Mechanism and consequences of herpes simplex virus 1-mediated regulation of host mRNA alternative polyadenylation

Authors:
Wang X, Liu L, Whisnant AW, Hennig T, Djakovic L, Haque N, Bach C, Sandri-Goldin RM, Erhard F, Friedel CC, Dölken L, Shi Y
Citation:
PLoS Genet. 2021 Mar 8;17(3):e1009263. doi: 10.1371/journal.pgen.1009263. PMID: 33684133; PMCID: PMC7971895.
Epub:
Not Epub
Abstract:
Eukaryotic gene expression is extensively regulated by cellular stress and pathogen infections. We have previously shown that...
Link:
https://pmc.ncbi.nlm.nih.gov/articles/PMC7971895/
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: HEK293
Citation Extract:
Wang X, Liu L, Whisnant AW, Hennig T, Djakovic L, Haque N, Bach C, Sandri-Goldin RM, Erhard F, Friedel CC, Dölken L, Shi Y. Mechanism and consequences of herpes simplex virus 1-mediated regulation of host mRNA alternative polyadenylation. PLoS Genet. 2021 Mar 8;17(3):e1009263. doi: 10.1371/journal.pgen.1009263. PMID: 33684133; PMCID: PMC7971895..

H2S promotes developmental brain angiogenesis via the NOS/NO pathway in zebrafish

Authors:
Jiang W, Liu C, Deng M, Wang F, Ren X, Fan Y, Du J, Wang Y
Citation:
Stroke Vasc Neurol. 2020 Nov 27:svn-2020-000584. doi: 10.1136/svn-2020-000584. Online ahead of print
Epub:
Yes
Abstract:
Background: Hydrogen sulphide (H2S) is considered as the third member of the gasotransmitter family, along with nitric oxide (...
Link:
https://svn.bmj.com/content/early/2020/11/26/svn-2020-000584
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Jiang W, Liu C, Deng M, Wang F, Ren X, Fan Y, Du J, Wang Y. H2S promotes developmental brain angiogenesis via the NOS/NO pathway in zebrafish. Stroke Vasc Neurol. 2020 Nov 27:svn-2020-000584. doi: 10.1136/svn-2020-000584. Online ahead of print.

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