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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12371 scientific papers returned from the database with the search filters currently being used below.

Multiscale analysis of architecture, cell size and the cell cortex reveals cortical F-actin density and composition are major contributors to mechanical properties during convergent extension

Authors:
Shawky JH, Balakrishnan UL, Stuckenholz C, Davidson LA
Citation:
Development. 2018 Sep 6. pii: dev.161281. doi: 10.1242/dev.161281. [Epub ahead of print]
Epub:
Yes
Abstract:
The large-scale movements that construct complex three-dimensional tissues during development are governed by universal...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Shawky JH, Balakrishnan UL, Stuckenholz C, Davidson LA. Multiscale analysis of architecture, cell size and the cell cortex reveals cortical F-actin density and composition are major contributors to mechanical properties during convergent extension. Development. 2018 Sep 6. pii: dev.161281. doi: 10.1242/dev.161281. [Epub ahead of print].

Cxcr1 mediates recruitment of neutrophils and supports proliferation of tumor-initiating astrocytes in vivo

Authors:
Powell D, Lou M, Barros Becker F, Huttenlocher A
Citation:
Sci Rep. 2018 Sep 5;8(1):13285. doi: 10.1038/s41598-018-31675-0
Epub:
Not Epub
Abstract:
Neutrophils are first-responders to sites of infection and tissue damage including the inflamed tumor microenvironment....
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Powell D, Lou M, Barros Becker F, Huttenlocher A. Cxcr1 mediates recruitment of neutrophils and supports proliferation of tumor-initiating astrocytes in vivo. Sci Rep. 2018 Sep 5;8(1):13285. doi: 10.1038/s41598-018-31675-0.

Dimerization quality control ensures neuronal development and survival

Authors:
Mena EL, Kjolby RAS, Saxton RA, Werner A, Lew BG, Boyle JM, Harland R, Rape M
Citation:
Science. 2018 Sep 6. pii: eaap8236. doi: 10.1126/science.aap8236. [Epub ahead of print]
Epub:
Yes
Abstract:
Aberrant complex formation by recurrent interaction modules, such as BTB domains, leucine zippers, or coiled coils, can disrupt...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Mena EL, Kjolby RAS, Saxton RA, Werner A, Lew BG, Boyle JM, Harland R, Rape M. Dimerization quality control ensures neuronal development and survival. Science. 2018 Sep 6. pii: eaap8236. doi: 10.1126/science.aap8236. [Epub ahead of print].

Small noncoding RNA profiles along alternative developmental trajectories in an annual killifish

Authors:
Romney ALT, Podrabsky JE
Citation:
Sci Rep. 2018;8:13364. doi:10.1038/s41598-018-31466-7
Epub:
Not Epub
Abstract:
Embryonic development of Austrofundulus limnaeus can occur along two phenotypic trajectories that are physiologically and...
Delivery Method:
microinjection
Organism or Cell Type:
Austrofundulus limnaeus (killifish)
Citation Extract:
Romney ALT, Podrabsky JE. Small noncoding RNA profiles along alternative developmental trajectories in an annual killifish. Sci Rep. 2018;8:13364. doi:10.1038/s41598-018-31466-7.

Phase Transitions Drive the Formation of Vesicular Stomatitis Virus Replication Compartments

Authors:
Heinrich BS, Maliga Z, Stein DA, Hyman AA, Whelan SPJ
Citation:
mBio. 2018;9:e02290-17. doi:10.1128/mBio.02290-17
Epub:
Not Epub
Abstract:
RNA viruses that replicate in the cell cytoplasm typically concentrate their replication machinery within specialized...
Delivery Method:
peptide-linked
Organism or Cell Type:
cell culture: Vero
Citation Extract:
Heinrich BS, Maliga Z, Stein DA, Hyman AA, Whelan SPJ. Phase Transitions Drive the Formation of Vesicular Stomatitis Virus Replication Compartments. mBio. 2018;9:e02290-17. doi:10.1128/mBio.02290-17.

Midgut Laterality Is Driven by Hyaluronan on the Right

Authors:
Sivakumar A, Mahadevan A, Lauer ME, Narvaez RJ, Ramesh S, Demler CM, Souchet NR, Hascall VC, Midura RJ, Garantziotis S, Frank DB, Kimata K, Kurpios NA
Citation:
Dev Cell. 2018 Aug 28. pii: S1534-5807(18)30638-5. doi: 10.1016/j.devcel.2018.08.002. [Epub ahead of print]
Epub:
Yes
Abstract:
For many years, biologists have focused on the role of Pitx2, expressed on the left side of developing embryos, in governing...
Delivery Method:
electroporation
Organism or Cell Type:
Gallus gallus (chick)
Citation Extract:
Sivakumar A, Mahadevan A, Lauer ME, Narvaez RJ, Ramesh S, Demler CM, Souchet NR, Hascall VC, Midura RJ, Garantziotis S, Frank DB, Kimata K, Kurpios NA. Midgut Laterality Is Driven by Hyaluronan on the Right. Dev Cell. 2018 Aug 28. pii: S1534-5807(18)30638-5. doi: 10.1016/j.devcel.2018.08.002. [Epub ahead of print].

PGE2 production at sites of tissue injury promotes an anti-inflammatory neutrophil phenotype and determines the outcome of inflammation resolution in vivo

Authors:
Loynes CA, Lee JA, Robertson AL, Steel MJG, Ellett F, Feng Y, Levy BD, Whyte MKB, Renshaw SA
Citation:
Sci Advances. 2018;4(9):eaar8320. doi:10.1126/sciadv.aar8320
Epub:
Not Epub
Abstract:
Neutrophils are the first immune cells recruited to a site of injury or infection, where they perform many functions. Having...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Loynes CA, Lee JA, Robertson AL, Steel MJG, Ellett F, Feng Y, Levy BD, Whyte MKB, Renshaw SA. PGE2 production at sites of tissue injury promotes an anti-inflammatory neutrophil phenotype and determines the outcome of inflammation resolution in vivo. Sci Advances. 2018;4(9):eaar8320. doi:10.1126/sciadv.aar8320.

Persistent Marburg Virus Infection in the Testes of Nonhuman Primate Survivors

Authors:
Coffin KM, Liu J, Warren TK, Blancett CD, Kuehl KA, Nichols DK, Bearss JJ, Schellhase CW, Retterer CJ, Weidner JM, Radoshitzky SR, Brannan JM, Cardile AP, Dye JM, Palacios G, Sun MG, Kuhn JH, Bavari S, Zeng X
Citation:
Cell Host Microbe. 2018 Sep 12;24(3):405-416.e3. doi: 10.1016/j.chom.2018.08.003. Epub 2018 Aug 30. PMID: 30173956
Epub:
Yes
Abstract:
Sexual transmission of filoviruses was first reported in 1968 after an outbreak of Marburg virus (MARV) disease and recently...
Organism or Cell Type:
Macaca fascicularis (crab-eating macaque, cynomolgus monkey)
Citation Extract:
Coffin KM, Liu J, Warren TK, Blancett CD, Kuehl KA, Nichols DK, Bearss JJ, Schellhase CW, Retterer CJ, Weidner JM, Radoshitzky SR, Brannan JM, Cardile AP, Dye JM, Palacios G, Sun MG, Kuhn JH, Bavari S, Zeng X. Persistent Marburg Virus Infection in the Testes of Nonhuman Primate Survivors. Cell Host Microbe. 2018 Sep 12;24(3):405-416.e3. doi: 10.1016/j.chom.2018.08.003. Epub 2018 Aug 30. PMID: 30173956.

Mutations in multiple components of the nuclear pore complex cause nephrotic syndrome

Authors:
Braun DA, Lovric S, Schapiro D, Schneider R, Marquez J, Asif M, Hussain MS, Daga A, Widmeier E, Rao J, Ashraf S, Tan W, Lusk CP, Kolb A, Jobst-Schwan T, Schmidt JM, Hoogstraten CA, Eddy K, Kitzler TM, Shril S, Moawia A, Schrage K, Khayyat AIA, Lawson JA, Gee HY, Warejko JK, Hermle T, Majmundar AJ, Hugo H, Budde B, Motameny S, Altmüller J, Noegel AA, Fathy HM, Gale DP, Waseem SS, Khan A, Kerecuk L, Hashmi S, Mohebbi N, Ettenger R, Serdaroğlu E, Alhasan KA, Hashem M, Goncalves S, Ariceta G, Ubetagoyena M, Antonin W, Baig SM, Alkuraya FS, Shen Q, Xu H, Antignac C, Lifton RP, Mane S, Nürnberg P, Khokha MK, Hildebrandt F
Citation:
J Clin Invest. 2018 Sep 4. pii: 98688. doi: 10.1172/JCI98688. [Epub ahead of print]
Epub:
Yes
Abstract:
Steroid-resistant nephrotic syndrome (SRNS) almost invariably progresses to end-stage renal disease. Although more than 50...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Braun DA, Lovric S, Schapiro D, Schneider R, Marquez J, Asif M, Hussain MS, Daga A, Widmeier E, Rao J, Ashraf S, Tan W, Lusk CP, Kolb A, Jobst-Schwan T, Schmidt JM, Hoogstraten CA, Eddy K, Kitzler TM, Shril S, Moawia A, Schrage K, Khayyat AIA, Lawson JA, Gee HY, Warejko JK, Hermle T, Majmundar AJ, Hugo H, Budde B, Motameny S, Altmüller J, Noegel AA, Fathy HM, Gale DP, Waseem SS, Khan A, Kerecuk L, Hashmi S, Mohebbi N, Ettenger R, Serdaroğlu E, Alhasan KA, Hashem M, Goncalves S, Ariceta G, Ubetagoyena M, Antonin W, Baig SM, Alkuraya FS, Shen Q, Xu H, Antignac C, Lifton RP, Mane S, Nürnberg P, Khokha MK, Hildebrandt F. Mutations in multiple components of the nuclear pore complex cause nephrotic syndrome. J Clin Invest. 2018 Sep 4. pii: 98688. doi: 10.1172/JCI98688. [Epub ahead of print].

Use of Glucose-Fructose to Enhance the Exon Skipping Efficacy

Authors:
Han G, Gao X, Yin H
Citation:
Methods Mol Biol. 2018;1828:327-342. doi: 10.1007/978-1-4939-8651-4_20
Epub:
Not Epub
Abstract:
Exon-skipping antisense oligonucleotides (AOs) are promising treatments for muscle-related genetic ailments including Duchenne...
Delivery Method:
injection
Organism or Cell Type:
mice mdx
Citation Extract:
Han G, Gao X, Yin H. Use of Glucose-Fructose to Enhance the Exon Skipping Efficacy. Methods Mol Biol. 2018;1828:327-342. doi: 10.1007/978-1-4939-8651-4_20.

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