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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
Targeting a single alternative polyadenylation site coordinately blocks expression of androgen receptor mRNA splice variants in prostate cancer
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Citation:
Cancer Res. 2017 Aug 15. pii: canres.0320.2017. doi: 10.1158/0008-5472.CAN-17-0320. [Epub ahead of print] Epub:
Yes Abstract:
Prostate cancer is the second leading cause of male cancer deaths due to disease progression to castration resistant prostate... Organism or Cell Type:
cell culture: castration resistant prostate cancer (CRPC) cells Citation Extract: Van Etten JL, Nyquist M, Li Y, Yang R, Ho Y, Johnson RM, Ondigi O, Voytas DF, Henzler C, Dehm SM. Targeting a single alternative polyadenylation site coordinately blocks expression of androgen receptor mRNA splice variants in prostate cancer. Cancer Res. 2017 Aug 15. pii: canres.0320.2017. doi: 10.1158/0008-5472.CAN-17-0320. [Epub ahead of print]. |
The RNF146 E3 ubiquitin ligase is required for the control of Wnt signaling and body pattern formation in Xenopus
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Citation:
Mech Dev. 2017 Aug 11. pii: S0925-4773(17)30074-6. doi: 10.1016/j.mod.2017.08.001. [Epub ahead of print] Epub:
Yes Abstract:
The RING finger protein Rnf146 encodes an E3 ubiquitin ligase capable of targeting poly-ADP-ribosylated substrates for... Delivery Method:
microinjection Organism or Cell Type:
Xenopus Citation Extract: Zhu X, Xing R, Tan R, Dai R, Tao Q. The RNF146 E3 ubiquitin ligase is required for the control of Wnt signaling and body pattern formation in Xenopus. Mech Dev. 2017 Aug 11. pii: S0925-4773(17)30074-6. doi: 10.1016/j.mod.2017.08.001. [Epub ahead of print]. |
Cell interactions, signals and transcriptional hierarchy governing placode progenitor induction
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Citation:
Development. 2017 Aug 1;144(15):2810-2823. doi: 10.1242/dev.147942. Epub 2017 Jul 6 Epub:
Not Epub Abstract:
In vertebrates, cranial placodes contribute to all sense organs and sensory ganglia and arise from a common pool of Six1/Eya2+... Delivery Method:
electroporation Organism or Cell Type:
Gallus gallus (chick) Citation Extract: Hintze M, Prajapati RS, Tambalo M, Christophorou NAD, Anwar M, Grocott T, Streit A. Cell interactions, signals and transcriptional hierarchy governing placode progenitor induction. Development. 2017 Aug 1;144(15):2810-2823. doi: 10.1242/dev.147942. Epub 2017 Jul 6. |
Wnt signalling controls the response to mechanical loading during zebrafish joint development
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Citation:
Development. 2017 Aug 1;144(15):2798-2809. doi: 10.1242/dev.153528. Epub 2017 Jul 6 Epub:
Not Epub Abstract:
Joint morphogenesis requires mechanical activity during development. Loss of mechanical strain causes abnormal joint... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Brunt LH, Begg K, Kague E, Cross S, Hammond CL. Wnt signalling controls the response to mechanical loading during zebrafish joint development. Development. 2017 Aug 1;144(15):2798-2809. doi: 10.1242/dev.153528. Epub 2017 Jul 6. |
Ikk2 regulates cytokinesis during vertebrate development
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Citation:
Sci Rep. 2017;7:8094. doi:10.1038/s41598-017-06904-7 Epub:
Not Epub Abstract:
NFκB signaling has a pivotal role in regulation of development, innate immunity, and inflammation. Ikk2 is one of the two... Organism or Cell Type:
zebrafish Citation Extract: Shen H, Shin EM, Lee S, Mathavan S, Koh H, Osato M, Choi H, Tergaonkar V, Korzh V. Ikk2 regulates cytokinesis during vertebrate development. Sci Rep. 2017;7:8094. doi:10.1038/s41598-017-06904-7. |
A Functional Assay for Sick Sinus Syndrome Genetic Variants
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Citation:
Cell Phys Biochem. 2017;42:2021-9. doi:10.1159/000479897 Epub:
Not Epub Abstract:
Background/Aims: Congenital Sick Sinus Syndrome (SSS) is a disorder associated with sudden cardiac death due to severe... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Jou CJ, Arrington CB, Barnett S, Shen J, Cho S, Sheng X, McCullagh PC, Bowles NE, Pribble CM, Saarel EV, Pilcher TA, Etheridge SP, Tristani-Firouzi M. A Functional Assay for Sick Sinus Syndrome Genetic Variants. Cell Phys Biochem. 2017;42:2021-9. doi:10.1159/000479897. |
The Vascular Niche Regulates Hematopoietic Stem and Progenitor Cell Lodgment and Expansion via klf6a-ccl25b
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Citation:
Dev Cell. 2017;[Epub ahead of print] doi:10.1016/j.devcel.2017.07.012 Epub:
Not Epub Abstract:
In mammals, hematopoietic stem and progenitor cells (HSPCs) rapidly expand in the fetal liver (FL), but the underlying... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Yuanyuan Xue Y, Lv J, Zhang C, Wang L, Ma D, Liu F. The Vascular Niche Regulates Hematopoietic Stem and Progenitor Cell Lodgment and Expansion via klf6a-ccl25b. Dev Cell. 2017;[Epub ahead of print] doi:10.1016/j.devcel.2017.07.012. |
TNF signaling and macrophages govern fin regeneration in zebrafish larvae
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Citation:
Cell Death Dis. 2017 Aug 10;8(8):e2979. doi: 10.1038/cddis.2017.374 Epub:
Not Epub Abstract:
Macrophages are essential for appendage regeneration after amputation in regenerative species. The molecular mechanisms through... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Nguyen-Chi M, Laplace-Builhé B, Travnickova J, Luz-Crawford P, Tejedor G, Lutfalla G, Kissa K, Jorgensen C, Djouad F. TNF signaling and macrophages govern fin regeneration in zebrafish larvae. Cell Death Dis. 2017 Aug 10;8(8):e2979. doi: 10.1038/cddis.2017.374. |
Regulation of Gli ciliary localization and Hedgehog signaling by the PY-NLS/karyopherin-β2 nuclear import system
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Citation:
PLoS Biol. 2017 Aug 4;15(8):e2002063. doi: 10.1371/journal.pbio.2002063. eCollection 2017 Aug Epub:
Not Epub Abstract:
Hedgehog (Hh) signaling in vertebrates depends on primary cilia. Upon stimulation, Hh pathway components, including Gli... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Han Y, Xiong Y, Shi X, Wu J, Zhao Y, Jiang J. Regulation of Gli ciliary localization and Hedgehog signaling by the PY-NLS/karyopherin-β2 nuclear import system. PLoS Biol. 2017 Aug 4;15(8):e2002063. doi: 10.1371/journal.pbio.2002063. eCollection 2017 Aug. |
CBFβ initiates the hematopoietic stem cell program without obligatory binding to RUNX
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Citation:
bioRxiv. 2017;[preprint] doi:10.1101/172957 Epub:
Not Epub Abstract:
Hematopoietic stem cells (HSCs) emerge from hemogenic endothelium (HE) localised in the embryonic dorsal aorta (DA). Here we... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Ciau-Uitz A, Pinheiro P, Kirmizitas A, Fernandez C, Patient R. CBFβ initiates the hematopoietic stem cell program without obligatory binding to RUNX. bioRxiv. 2017;[preprint] doi:10.1101/172957. |