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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
Quantitative Proteomics Analysis Reveals Novel Targets of miR-21 in Zebrafish Embryos
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Citation:
Sci Rep. 2017 Jun 22;7(1):4022. doi: 10.1038/s41598-017-04166-x Epub:
Not Epub Abstract:
MicroRNAs (miRNAs) are noncoding RNAs which control gene expression by the suppression of translation or the degradation of... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Wu Y, Lou QY, Ge F, Xiong Q. Quantitative Proteomics Analysis Reveals Novel Targets of miR-21 in Zebrafish Embryos. Sci Rep. 2017 Jun 22;7(1):4022. doi: 10.1038/s41598-017-04166-x. |
A homozygous founder mutation in TRAPPC6B associates with a neurodevelopmental disorder characterised by microcephaly, epilepsy and autistic features
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Citation:
J Med Genet. 2017 Jun 16. pii: jmedgenet-2017-104627. doi: 10.1136/jmedgenet-2017-104627. [Epub ahead of print] Epub:
Yes Abstract:
Background: Transport protein particle (TRAPP) is a multisubunit complex that regulates membrane trafficking through the Golgi... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Marin-Valencia I, Novarino G, Johansen A, Rosti B, Issa MY, Musaev D, Bhat G, Scott E, Silhavy JL, Stanley V, Rosti RO, Gleeson JW, Imam FB, Zaki MS, Gleeson JG. A homozygous founder mutation in TRAPPC6B associates with a neurodevelopmental disorder characterised by microcephaly, epilepsy and autistic features. J Med Genet. 2017 Jun 16. pii: jmedgenet-2017-104627. doi: 10.1136/jmedgenet-2017-104627. [Epub ahead of print]. |
miR-27 regulates chondrogenesis by suppressing focal adhesion kinase during pharyngeal arch development
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Citation:
Dev Biol. 2017 Jun 16. pii: S0012-1606(16)30850-8. doi: 10.1016/j.ydbio.2017.06.013. [Epub ahead of print] Epub:
Not Epub Abstract:
Cranial neural crest cells are a multipotent cell population that generate all the elements of the pharyngeal cartilage with... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Kara N, Wei C, Commanday AC, Patton JG. miR-27 regulates chondrogenesis by suppressing focal adhesion kinase during pharyngeal arch development. Dev Biol. 2017 Jun 16. pii: S0012-1606(16)30850-8. doi: 10.1016/j.ydbio.2017.06.013. [Epub ahead of print]. |
The Short-Stature Homeobox-Containing Gene (shox/SHOX) Is Required for the Regulation of Cell Proliferation and Bone Differentiation in Zebrafish Embryo and Human Mesenchymal Stem Cells
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Citation:
Front Endocrinol (Lausanne). 2017 Jun 8;8:125. doi: 10.3389/fendo.2017.00125. eCollection 2017 Epub:
Not Epub Abstract:
The short-stature homeobox-containing gene (SHOX) was originally discovered as one of genes responsible for idiopathic short-... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Yokokura T, Kamei H, Shibano T, Yamanaka D, Sawada-Yamaguchi R, Hakuno F, Takahashi SI, Shimizu T. The Short-Stature Homeobox-Containing Gene (shox/SHOX) Is Required for the Regulation of Cell Proliferation and Bone Differentiation in Zebrafish Embryo and Human Mesenchymal Stem Cells. Front Endocrinol (Lausanne). 2017 Jun 8;8:125. doi: 10.3389/fendo.2017.00125. eCollection 2017. |
Mitochondrion to endoplasmic reticulum apposition length in zebrafish embryo spinal progenitors is unchanged in response to perturbations associated with Alzheimer's disease
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Citation:
PLoS One. 2017 Jun 21;12(6):e0179859. doi: 10.1371/journal.pone.0179859. eCollection 2017 Epub:
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Mutations in the human genes PRESENILIN1 (PSEN1), PRESENILIN2 (PSEN2) and AMYLOID BETA A4 PRECURSOR PROTEIN (APP) have been... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Newman M, Halter L, Lim A, Lardelli M. Mitochondrion to endoplasmic reticulum apposition length in zebrafish embryo spinal progenitors is unchanged in response to perturbations associated with Alzheimer's disease. PLoS One. 2017 Jun 21;12(6):e0179859. doi: 10.1371/journal.pone.0179859. eCollection 2017. |
Polyquaternium-mediated delivery of morpholino oligonucleotides for exon-skipping in vitro and in mdx mice
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Citation:
Drug Deliv. 2017 Nov;24(1):952-961. doi: 10.1080/10717544.2017.1337827 Epub:
Not Epub Abstract:
Antisense oligonucleotide therapy for Duchenne muscular dystrophy has shown great potential in preclinical and clinical trials... Delivery Method:
polyquaternium Organism or Cell Type:
cell culture, mouse Citation Extract: Wang M, Wu B, Shah SN, Lu P, Lu Q. Polyquaternium-mediated delivery of morpholino oligonucleotides for exon-skipping in vitro and in mdx mice. Drug Deliv. 2017 Nov;24(1):952-961. doi: 10.1080/10717544.2017.1337827. |
An Integrative Developmental Genomics and Systems Biology Approach to Identify an In Vivo Sox Trio-Mediated Gene Regulatory Network in Murine Embryos
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Citation:
Biomed Res Int. 2017;2017:8932583. doi: 10.1155/2017/8932583. Epub 2017 May 28 Epub:
Not Epub Abstract:
Embryogenesis is an intricate process involving multiple genes and pathways. Some of the key transcription factors controlling... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Lee WJ, Chatterjee S, Yap SP, Lim SL, Xing X, Kraus P, Sun W, Hu X, Sivakamasundari V, Chan HY, Kolatkar PR, Prabhakar S, Lufkin T. An Integrative Developmental Genomics and Systems Biology Approach to Identify an In Vivo Sox Trio-Mediated Gene Regulatory Network in Murine Embryos. Biomed Res Int. 2017;2017:8932583. doi: 10.1155/2017/8932583. Epub 2017 May 28. |
Irf8 regulates the progression of myeloproliferative neoplasm (MPN)-like syndrome via Mertk signaling in zebrafish
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Citation:
Leukemia. 2017 Jun 19. doi: 10.1038/leu.2017.189. [Epub ahead of print] Epub:
Yes Abstract:
Interferon regulatory factor (IRF)-8 is a critical transcription factor involved in the pathogenesis of myeloid neoplasia.... Organism or Cell Type:
zebrafish Citation Extract: Zhao F, Shi Y, Huang Y, Zhan Y, Zhou L, Li Y, Wan Y, Li H, Huang H, Ruan H, Luo L, Li L. Irf8 regulates the progression of myeloproliferative neoplasm (MPN)-like syndrome via Mertk signaling in zebrafish. Leukemia. 2017 Jun 19. doi: 10.1038/leu.2017.189. [Epub ahead of print]. |
Antisense Oligonucleotides Promote Exon Inclusion and Correct the Common c.-32-13T>G GAA Splicing Variant in Pompe Disease
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Citation:
Mol Ther Nucleic Acids. 2017 Jun 16;7:90-100. doi: 10.1016/j.omtn.2017.03.001. Epub 2017 Mar 14 Epub:
Not Epub Abstract:
The most common variant causing Pompe disease is c.-32-13T>G (IVS1) in the acid α-glucosidase (GAA) gene, which weakens the... Delivery Method:
Endo-Porter Organism or Cell Type:
cell culture: human primary fibroblasts Citation Extract: van der Wal E, Bergsma AJ, Pijnenburg JM, van der Ploeg AT, Pijnappel WWMP. Antisense Oligonucleotides Promote Exon Inclusion and Correct the Common c.-32-13T>G GAA Splicing Variant in Pompe Disease. Mol Ther Nucleic Acids. 2017 Jun 16;7:90-100. doi: 10.1016/j.omtn.2017.03.001. Epub 2017 Mar 14. |
Presenilin-1 Targeted Morpholino Induces Cognitive Deficits, Increased Brain Aβ<sub>1-42</sub> and Decreased Synaptic Marker PSD-95 in Zebrafish Larvae
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Citation:
Neurochem Res. 2017 Jun 16. doi: 10.1007/s11064-017-2327-4. [Epub ahead of print] Epub:
Not Epub Abstract:
Presenilins are transmembrane proteases required for the proteolytic cleavage of Notch and also act as the catalytic core of... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Nery LR, Silva NE, Fonseca R, Vianna MRM. Presenilin-1 Targeted Morpholino Induces Cognitive Deficits, Increased Brain Aβ<sub>1-42</sub> and Decreased Synaptic Marker PSD-95 in Zebrafish Larvae. Neurochem Res. 2017 Jun 16. doi: 10.1007/s11064-017-2327-4. [Epub ahead of print]. |