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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12376 scientific papers returned from the database with the search filters currently being used below.

Zebrafish Znfl1s control the expression of hoxb1b in the posterior neuroectoderm by acting upstream of pou5f3 and sall4

Authors:
Dong X, Li J, He L, Gu C, Jia W, Yue Y, Li J, Zhang Q, Chu L, Zhao Q
Citation:
J Biol Chem. 2017 Jun 16. pii: jbc.M117.777094. doi: 10.1074/jbc.M117.777094. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Transcription factors play crucial roles in patterning posterior neuroectoderm. Previously, zinc finger transcription factor...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Dong X, Li J, He L, Gu C, Jia W, Yue Y, Li J, Zhang Q, Chu L, Zhao Q. Zebrafish Znfl1s control the expression of hoxb1b in the posterior neuroectoderm by acting upstream of pou5f3 and sall4. J Biol Chem. 2017 Jun 16. pii: jbc.M117.777094. doi: 10.1074/jbc.M117.777094. [Epub ahead of print].

FoxD1 protein interacts with Wnt and BMP signaling to differentially pattern mesoderm and neural tissue

Authors:
Polevoy H, Malyarova A, Fonar Y, Elias S, Frank D
Citation:
Int J Dev Biol. 2017;61(3-4-5):293-302. doi: 10.1387/ijdb.160300df
Epub:
Not Epub
Abstract:
The foxd1 gene (previously known as Brain Factor 2/BF2) is expressed during early Xenopus laevis development. At gastrula...
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Polevoy H, Malyarova A, Fonar Y, Elias S, Frank D. FoxD1 protein interacts with Wnt and BMP signaling to differentially pattern mesoderm and neural tissue. Int J Dev Biol. 2017;61(3-4-5):293-302. doi: 10.1387/ijdb.160300df.

Whole Exome Sequencing Identifies Truncating Variants in Nuclear Envelope Genes in Patients With Cardiovascular Disease

Authors:
Haskell GT, Jensen BC, Samsa LA, Marchuk D, Huang W, Skrzynia C, Tilley C, Seifert BA, Rivera-Muñoz EA, Koller B, Wilhelmsen KC, Liu J, Alhosaini H, Weck KE, Evans JP, Berg JS
Citation:
Circ Cardiovasc Genet. 2017 Jun;10(3). pii: e001443. doi: 10.1161/CIRCGENETICS.116.001443
Epub:
Not Epub
Abstract:
Recent findings indicate that growth factor-driven angiogenesis is markedly influenced by genetic variation. This variation in...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Haskell GT, Jensen BC, Samsa LA, Marchuk D, Huang W, Skrzynia C, Tilley C, Seifert BA, Rivera-Muñoz EA, Koller B, Wilhelmsen KC, Liu J, Alhosaini H, Weck KE, Evans JP, Berg JS. Whole Exome Sequencing Identifies Truncating Variants in Nuclear Envelope Genes in Patients With Cardiovascular Disease. Circ Cardiovasc Genet. 2017 Jun;10(3). pii: e001443. doi: 10.1161/CIRCGENETICS.116.001443.

Whole Exome Sequencing Identifies Truncating Variants in Nuclear Envelope Genes in Patients With Cardiovascular Disease

Authors:
Haskell GT, Jensen BC, Samsa LA, Marchuk D, Huang W, Skrzynia C, Tilley C, Seifert BA, Rivera-Muñoz EA, Koller B, Wilhelmsen KC, Liu J, Alhosaini H, Weck KE, Evans JP, Berg JS
Citation:
Circ Cardiovasc Genet. 2017 Jun;10(3). pii: e001443. doi: 10.1161/CIRCGENETICS.116.001443
Epub:
Yes
Abstract:
BACKGROUND: The genetic variation underlying many heritable forms of cardiovascular disease is incompletely understood, even in...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Haskell GT, Jensen BC, Samsa LA, Marchuk D, Huang W, Skrzynia C, Tilley C, Seifert BA, Rivera-Muñoz EA, Koller B, Wilhelmsen KC, Liu J, Alhosaini H, Weck KE, Evans JP, Berg JS. Whole Exome Sequencing Identifies Truncating Variants in Nuclear Envelope Genes in Patients With Cardiovascular Disease. Circ Cardiovasc Genet. 2017 Jun;10(3). pii: e001443. doi: 10.1161/CIRCGENETICS.116.001443.

Targeted gene knockdown validates the essential role of lactate dehydrogenase in Cryptosporidium parvum

Authors:
Witola WH, Zhang X, Kim CY
Citation:
Int J Parasitol. 2017 Jun 9. pii: S0020-7519(17)30166-2. doi: 10.1016/j.ijpara.2017.05.002. [Epub ahead of print]
Epub:
Yes
Abstract:
Cryptosporidium parvum is a zoonotic protozoan that can cause a life-threatening gastrointestinal syndrome in children and in...
Delivery Method:
Vivo-Morpholino, Endo-Porter
Organism or Cell Type:
Cryptosporidium parvum
Citation Extract:
Witola WH, Zhang X, Kim CY. Targeted gene knockdown validates the essential role of lactate dehydrogenase in Cryptosporidium parvum. Int J Parasitol. 2017 Jun 9. pii: S0020-7519(17)30166-2. doi: 10.1016/j.ijpara.2017.05.002. [Epub ahead of print].

Inhibition of microRNA-24 increases liver fibrosis by enhanced menin expression in Mdr2-/- mice

Authors:
Hall C, Ehrlich L, Meng F, Invernizzi P, Bernuzzi F, Lairmore TC, Alpini G, Glaser S
Citation:
J Surg Res. 2017 May 11. pii: S0022-4804(17)30273-1. doi: 10.1016/j.jss.2017.05.020. [Epub ahead of print]
Epub:
Yes
Abstract:
BACKGROUND: Liver transplantation remains the primary treatment for primary sclerosing cholangitis (PSC). Mdr2-/- mice provide...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
mice Mdr2-/-
Citation Extract:
Hall C, Ehrlich L, Meng F, Invernizzi P, Bernuzzi F, Lairmore TC, Alpini G, Glaser S. Inhibition of microRNA-24 increases liver fibrosis by enhanced menin expression in Mdr2-/- mice. J Surg Res. 2017 May 11. pii: S0022-4804(17)30273-1. doi: 10.1016/j.jss.2017.05.020. [Epub ahead of print].

Cationic Cytosine Morpholino-Based Transporters: Synthesis and Regulation of Intracellular Localization

Authors:
Nandi B, Khatra H, Khan PP, Bhadra J, Pattanayak S, Sinha S.
Citation:
ChemistrySelect. 2017;2:5059-67 doi:10.1002/slct.201700238
Epub:
Not Epub
Abstract:
Cationic guanidinium and phosphonium functionalized cytosine morpholino tetramer (G3) and trimer (P3) have been reported for...
Delivery Method:
modified cationic cytosine moieties
Organism or Cell Type:
zebrafish
Citation Extract:
Nandi B, Khatra H, Khan PP, Bhadra J, Pattanayak S, Sinha S.. Cationic Cytosine Morpholino-Based Transporters: Synthesis and Regulation of Intracellular Localization. ChemistrySelect. 2017;2:5059-67 doi:10.1002/slct.201700238.

Integration of over 9,000 mass spectrometry experiments builds a global map of human protein complexes

Authors:
Drew K, Lee C, Huizar RL, Tu F, Borgeson B, McWhite CD, Ma Y, Wallingford JB, Marcotte EM
Citation:
Mol Syst Biol. 2017 Jun 8;13(6):932. doi: 10.15252/msb.20167490
Epub:
Yes
Abstract:
Macromolecular protein complexes carry out many of the essential functions of cells, and many genetic diseases arise from...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Drew K, Lee C, Huizar RL, Tu F, Borgeson B, McWhite CD, Ma Y, Wallingford JB, Marcotte EM. Integration of over 9,000 mass spectrometry experiments builds a global map of human protein complexes. Mol Syst Biol. 2017 Jun 8;13(6):932. doi: 10.15252/msb.20167490.

The signalling receptor MCAM coordinates apical-basal polarity and planar cell polarity during morphogenesis

Authors:
Gao Q, Zhang J, Wang X, Liu Y, He R, Liu X, Wang F, Feng J, Yang D, Wang Z, Meng A, Yan X
Citation:
Nat Commun. 2017 Jun 7;8:15279. doi: 10.1038/ncomms15279
Epub:
Yes
Abstract:
The apical-basal (AB) polarity and planar cell polarity (PCP) provide an animal cell population with different phenotypes...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish and Xenopus laevis
Citation Extract:
Gao Q, Zhang J, Wang X, Liu Y, He R, Liu X, Wang F, Feng J, Yang D, Wang Z, Meng A, Yan X. The signalling receptor MCAM coordinates apical-basal polarity and planar cell polarity during morphogenesis. Nat Commun. 2017 Jun 7;8:15279. doi: 10.1038/ncomms15279.

Essential but partially redundant roles for POU4F1/Brn-3a and POU4F2/Brn-3b transcription factors in the developing heart

Authors:
Maskell LJ, Qamar K, Babakr AA, Hawkins TA, Heads RJ, Budhram-Mahadeo VS
Citation:
Cell Death Dis. 2017 Jun 8;8(6):e2861. doi: 10.1038/cddis.2017.185
Epub:
Not Epub
Abstract:
Congenital heart defects contribute to embryonic or neonatal lethality but due to the complexity of cardiac development, the...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Maskell LJ, Qamar K, Babakr AA, Hawkins TA, Heads RJ, Budhram-Mahadeo VS. Essential but partially redundant roles for POU4F1/Brn-3a and POU4F2/Brn-3b transcription factors in the developing heart. Cell Death Dis. 2017 Jun 8;8(6):e2861. doi: 10.1038/cddis.2017.185.

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