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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
There are 12376 scientific papers returned from the database with the search filters currently being used below.
MiR-145 mediates zebrafish hepatic outgrowth through progranulin A signaling
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Citation:
PLoS ONE. 2017;12(5):e0177887. doi:0.1371/journal.pone.0177887 Epub:
Not Epub Abstract:
MicroRNAs (miRs) are mRNA-regulatory molecules that fine-tune gene expression and modulate both processes of development and... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Li Y-W, Chiang K-Y, Li Y-H, Wu S-Y, Liu W, Lin C-R, Wu J-L. MiR-145 mediates zebrafish hepatic outgrowth through progranulin A signaling. PLoS ONE. 2017;12(5):e0177887. doi:0.1371/journal.pone.0177887. |
Repression of phosphatidylinositol transfer protein α ameliorates the pathology of Duchenne muscular dystrophy
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Citation:
PNAS USA. 2017;[Epub ahead of print] doi: 10.1073/pnas.1703556114 Epub:
Yes Abstract:
Duchenne muscular dystrophy (DMD) is a progressive muscle wasting disease caused by X-linked inherited mutations in the... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Vieira NM, Spinazzola JM, Alexander MS, Moreira YB, Kawahara G, Gibbs DE, Mead LC, Verjovski-Almeida S, Zatz M, Kunkel LM. Repression of phosphatidylinositol transfer protein α ameliorates the pathology of Duchenne muscular dystrophy. PNAS USA. 2017;[Epub ahead of print] doi: 10.1073/pnas.1703556114. |
Modulation of nuclear REST by alternative splicing: a potential therapeutic target for Huntington's disease
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Citation:
J Cell Mol Med. 2017 May 19. doi: 10.1111/jcmm.13209. [Epub ahead of print] Epub:
Yes Abstract:
Huntington's disease (HD) is caused by a genetically mutated huntingtin (mHtt) protein with expanded polyQ stretch, which... Delivery Method:
Endo-Porter Organism or Cell Type:
cell culture: STHdhQ7/7 and STHdhQ111/111 from transgenic humanized mice Citation Extract: Chen GL, Ma Q, Goswami D, Shang J, Miller GM. Modulation of nuclear REST by alternative splicing: a potential therapeutic target for Huntington's disease. J Cell Mol Med. 2017 May 19. doi: 10.1111/jcmm.13209. [Epub ahead of print]. |
Activating transcription factor 3 promotes spinal cord regeneration of adult zebrafish
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Citation:
Biochem Biophys Res Commun. 2017 May 15. pii: S0006-291X(17)30953-1. doi: 10.1016/j.bbrc.2017.05.079. [Epub ahead of print] Epub:
Yes Abstract:
Zebrafish is an excellent model to study the mechanisms underlying successful central nervous system (CNS) regeneration.... Organism or Cell Type:
zebrafish Citation Extract: Wang LF, Huang SB, Zhao HD, Liu CJ, Yao L, Shen YQ. Activating transcription factor 3 promotes spinal cord regeneration of adult zebrafish. Biochem Biophys Res Commun. 2017 May 15. pii: S0006-291X(17)30953-1. doi: 10.1016/j.bbrc.2017.05.079. [Epub ahead of print]. |
Hif-1α regulates macrophage-endothelial interactions during blood vessel development in zebrafish
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Citation:
Nat Comm. 2017;8:15492. doi:10.1038/ncomms15492 Epub:
Not Epub Abstract:
Macrophages are known to interact with endothelial cells during developmental and pathological angiogenesis but the molecular... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Gerri C, Marín-Juez R, Marass M, Marks A, Maischein H-M, Stainier DYR. Hif-1α regulates macrophage-endothelial interactions during blood vessel development in zebrafish. Nat Comm. 2017;8:15492. doi:10.1038/ncomms15492. |
Characterization of TRPA channels in the starfish Patiria pectinifera: involvement of thermally activated TRPA1 in thermotaxis in marine planktonic larvae
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Citation:
Sci Rep. 2017;7:2173. doi:10.1038/s41598-017-02171-8 Epub:
Not Epub Abstract:
The vast majority of marine invertebrates spend their larval period as pelagic plankton and are exposed to various... Delivery Method:
microinjection Organism or Cell Type:
Patiria pectinifera (sea star) Citation Extract: Saito S, Hamanaka G, Kawai N, Furukawa R, Gojobori J, Tominaga M, Kaneko H, Satta Y. Characterization of TRPA channels in the starfish Patiria pectinifera: involvement of thermally activated TRPA1 in thermotaxis in marine planktonic larvae. Sci Rep. 2017;7:2173. doi:10.1038/s41598-017-02171-8. |
Quantitative determination of AVI-7100 (Radavirsen), a phosphorodiamidate morpholino oligomer (PMOplus®), in human plasma using LC-MS/MS
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Citation:
Bioanalysis. 2017 May 18. doi: 10.4155/bio-2016-0289. [Epub ahead of print] Epub:
Yes Abstract:
AIM: AVI-7100 (Radavirsen) is a 20-mer phosphorodiamidate morpholino oligomer (PMOplus®) for the treatment of influenza.... Organism or Cell Type:
human Citation Extract: Meng M, Zhang J, Liu A, Reuschel S, Sazani P, Wong M. Quantitative determination of AVI-7100 (Radavirsen), a phosphorodiamidate morpholino oligomer (PMOplus®), in human plasma using LC-MS/MS. Bioanalysis. 2017 May 18. doi: 10.4155/bio-2016-0289. [Epub ahead of print]. |
TGFβ mediated structural remodeling facilitates optic fissure fusion and the necessity of BMP antagonism in this process
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Citation:
bioRxiv. 2017;doi:10.1101/131599 Epub:
Not Epub Abstract:
The optic fissure is a transient gap in the developing vertebrate eye, which must be closed as development proceeds. A... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Knickmeyer MD, Mateo JL, Eckert P, Roussa E, Rahhal B, Zuniga A, Krieglstein K, Wittbrodt J, Heermann S. TGFβ mediated structural remodeling facilitates optic fissure fusion and the necessity of BMP antagonism in this process. bioRxiv. 2017;doi:10.1101/131599 . |
Ectopically expressed Slc34a2a sense-antisense transcripts cause a cerebellar phenotype in zebrafish embryos depending on RNA complementarity and Dicer
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Citation:
PLoS ONE. 2017;12(5):e0178219. doi:10.1371/journal.pone.0178219 Epub:
Not Epub Abstract:
Natural antisense transcripts (NATs) are complementary to protein coding genes and potentially regulate their expression.... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Piatek MJ, Henderson V, Fearn A, Chaudhry B, Werner A. Ectopically expressed Slc34a2a sense-antisense transcripts cause a cerebellar phenotype in zebrafish embryos depending on RNA complementarity and Dicer. PLoS ONE. 2017;12(5):e0178219. doi:10.1371/journal.pone.0178219. |
Interstitial fluid osmolarity modulates the action of differential tissue surface tension in progenitor cell segregation during gastrulation
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Citation:
Development. 2017;144:1798-806. doi:10.1242/dev.144964 Epub:
Not Epub Abstract:
The segregation of different cell types into distinct tissues is a fundamental process in metazoan development. Differences in... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Krens SFG, Veldhuis JH, Barone V, Čapek D, Maître J-L, Brodland GW, Heisenberg C-P. Interstitial fluid osmolarity modulates the action of differential tissue surface tension in progenitor cell segregation during gastrulation. Development. 2017;144:1798-806. doi:10.1242/dev.144964. |