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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12146 scientific papers returned from the database with the search filters currently being used below.
There are 12146 scientific papers returned from the database with the search filters currently being used below.
A switch in pdgfrb+ cell-derived ECM composition prevents inhibitory scarring and promotes axon regeneration in the zebrafish spinal cord
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Citation:
Dev Cell. 2021;[Epub ahead of print] doi:10.1016/j.devcel.2020.12.009 Epub:
Not Epub Abstract:
In mammals, perivascular cell-derived scarring after spinal cord injury impedes axonal regrowth. In contrast, the extracellular... Delivery Method:
Vivo-Morpholino pericardial vein injection Organism or Cell Type:
zebrafish Citation Extract: Tsata V, Möllmert S, Schweitzer C, Kolb J, Möckel C, Böhm B, Rosso G, Lange C, Lesche M, Hammer J, Kesavan G, Beis D, Guck J, Brand M, Wehner D. A switch in pdgfrb+ cell-derived ECM composition prevents inhibitory scarring and promotes axon regeneration in the zebrafish spinal cord. Dev Cell. 2021;[Epub ahead of print] doi:10.1016/j.devcel.2020.12.009. |
Ectoderm to mesoderm transition by down-regulation of actomyosin contractility
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Citation:
PLoS Biol. 2021;19(1):e3001060. doi:10.1371/journal.pbio.3001060 Epub:
Not Epub Abstract:
Collective migration of cohesive tissues is a fundamental process in morphogenesis and is particularly well illustrated during... Delivery Method:
microinjection Organism or Cell Type:
Xenopus Citation Extract: Kashkooli L, Rozema D, Espejo-Ramirez L, Lasko P, Fagotto F. Ectoderm to mesoderm transition by down-regulation of actomyosin contractility. PLoS Biol. 2021;19(1):e3001060. doi:10.1371/journal.pbio.3001060. |
The administration of antisense oligonucleotide golodirsen reduces pathological regeneration in patients with Duchenne muscular dystrophy
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Citation:
Acta Neuropathol Commun. 2021 Jan 6;9(1):7. doi: 10.1186/s40478-020-01106-1 Epub:
Not Epub Abstract:
During the last decade, multiple clinical trials for Duchenne muscular dystrophy (DMD) have focused on the induction of... Delivery Method:
i.v. infusion Organism or Cell Type:
human Citation Extract: Scaglioni D, Catapano F, Ellis M, Torelli S, Chambers D, Feng L, Beck M, Sewry C, Monforte M, Harriman S, Koenig E, Malhotra J, Popplewell L, Guglieri M, Straub V, Mercuri E, Servais L, Phadke R, Morgan J, Muntoni F. The administration of antisense oligonucleotide golodirsen reduces pathological regeneration in patients with Duchenne muscular dystrophy. Acta Neuropathol Commun. 2021 Jan 6;9(1):7. doi: 10.1186/s40478-020-01106-1. |
Attenuation of Antiviral Immune Response Caused by Perturbation of TRIM25-Mediated RIG-I Activation under Simulated Microgravity
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Citation:
Cell Rep. 2021;34(1):108600. doi:10.1016/j.celrep.2020.108600 Epub:
Not Epub Abstract:
Microgravity is a major environmental factor of space flight that triggers dysregulation of the immune system and increases... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Zhu L, Nie L, Xie S, Li M, Zhu C, Qiu X, Kuang J, Liu C, Lu C, Li W, Meng E, Zhang D, Zhu L. Attenuation of Antiviral Immune Response Caused by Perturbation of TRIM25-Mediated RIG-I Activation under Simulated Microgravity. Cell Rep. 2021;34(1):108600. doi:10.1016/j.celrep.2020.108600. |
Loss of PIGK function causes severe infantile encephalopathy and extensive neuronal apoptosis
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Citation:
Hum Genet. 2021 Jan 4. doi: 10.1007/s00439-020-02243-2. Online ahead of print Epub:
Yes Abstract:
PIGK gene, encoding a key component of glycosylphosphatidylinositol (GPI) transamidase, was recently reported to be associated... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Chen X, Yin W, Chen S, Zhang W, Li H, Kuang H, Zhou M, Teng Y, Zhang J, Shen G, Liang D, Li Z, Hu B, Wu L. Loss of PIGK function causes severe infantile encephalopathy and extensive neuronal apoptosis. Hum Genet. 2021 Jan 4. doi: 10.1007/s00439-020-02243-2. Online ahead of print. |
HSP60 regulates monosodium urate crystal-induced inflammation by activating the TLR4-NF- κ B-MyD88 signaling pathway and disrupting mitochondrial function
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Citation:
Oxid Med Cell Longev. 2020;[Epub] doi:10.1155/2020/8706898 Epub:
Yes Abstract:
Acute gout is an inflammatory response induced by monosodium urate (MSU) crystals. HSP60 is a highly conserved stress protein... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
mice Citation Extract: Gao W, Huang Q, Qin T, Mu H, Long F, Ren L, Tang H, Liu J, Zeng M. HSP60 regulates monosodium urate crystal-induced inflammation by activating the TLR4-NF- κ B-MyD88 signaling pathway and disrupting mitochondrial function. Oxid Med Cell Longev. 2020;[Epub] doi:10.1155/2020/8706898. |
A globin-family protein, cytoglobin 1, is involved in the development of neural crest-derived tissues and organs in zebrafish
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Citation:
Dev Biol. 2020 Dec 22:S0012-1606(20)30325-0. doi: 10.1016/j.ydbio.2020.12.016. Online ahead of print Epub:
Yes Abstract:
The zebrafish is an excellent model animal that is amenable to forward genetics approaches. To uncover unknown developmental... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Takahashi K, Ito Y, Yoshimura M, Nikaido M, Yuikawa T, Kawamura A, Tsuda S, Kage D, Yamasu K. A globin-family protein, cytoglobin 1, is involved in the development of neural crest-derived tissues and organs in zebrafish. Dev Biol. 2020 Dec 22:S0012-1606(20)30325-0. doi: 10.1016/j.ydbio.2020.12.016. Online ahead of print. |
CircRNA-SORE mediates sorafenib resistance in hepatocellular carcinoma by stabilizing YBX1
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Citation:
Signal Transduct Target Ther. 2020 Dec 26;5(1):298. doi: 10.1038/s41392-020-00375-5 Epub:
Not Epub Abstract:
Sorafenib is the first-line chemotherapeutic therapy for advanced hepatocellular carcinoma (HCC). However, sorafenib resistance... Organism or Cell Type:
cell culture: HepG2-SR Citation Extract: Xu J, Ji L, Liang Y, Wan Z, Zheng W, Song X, Gorshkov K, Sun Q, Lin H, Zheng X, Chen J, Jin RA, Liang X, Cai X. CircRNA-SORE mediates sorafenib resistance in hepatocellular carcinoma by stabilizing YBX1. Signal Transduct Target Ther. 2020 Dec 26;5(1):298. doi: 10.1038/s41392-020-00375-5. |
Mutation in epsilon-Sarcoglycan Induces a Myoclonus-Dystonia Syndrome-Like Movement Disorder in Mice
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Citation:
Neurosci Bull. 2020 Dec 23. doi: 10.1007/s12264-020-00612-5. Online ahead of print Epub:
Not Epub Abstract:
Myoclonus dystonia syndrome (MDS) is an inherited movement disorder, and most MDS-related mutations have so far been found in... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Li J, Liu Y, Li Q, Huang X, Zhou D, Xu H, Zhao F, Mi X, Wang R, Jia F, Xu F, Yang J, Liu D, Deng X, Zhang Y. Mutation in epsilon-Sarcoglycan Induces a Myoclonus-Dystonia Syndrome-Like Movement Disorder in Mice. Neurosci Bull. 2020 Dec 23. doi: 10.1007/s12264-020-00612-5. Online ahead of print. |
Discovery and Mechanistic Characterization of a Select Modulator of AhR-regulated Transcription (SMAhRT) with Anti-cancer Effects
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Citation:
Apoptosis. 2021 Jun;26(5-6):307-322. doi: 10.1007/s10495-021-01666-0. Epub 2021 Apr 24. PMID: 33893898 Epub:
Not Epub Abstract:
The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor and a member of the bHLH/PAS (basic Helix-Loop-... Delivery Method:
peptide-linked Organism or Cell Type:
cell culture: Hepa 1 Citation Extract: O'Donnell EF 3rd, Jang HS, Liefwalker DF, Kerkvliet NI, Kolluri SK. Discovery and Mechanistic Characterization of a Select Modulator of AhR-regulated Transcription (SMAhRT) with Anti-cancer Effects. Apoptosis. 2021 Jun;26(5-6):307-322. doi: 10.1007/s10495-021-01666-0. Epub 2021 Apr 24. PMID: 33893898. |